DK132174C - Analogifremgangsmade til fremstilling af 2,4-diamino-5-benzylpyrimidiner - Google Patents

Analogifremgangsmade til fremstilling af 2,4-diamino-5-benzylpyrimidiner

Info

Publication number
DK132174C
DK132174C DK513771A DK513771A DK132174C DK 132174 C DK132174 C DK 132174C DK 513771 A DK513771 A DK 513771A DK 513771 A DK513771 A DK 513771A DK 132174 C DK132174 C DK 132174C
Authority
DK
Denmark
Prior art keywords
benzylpyrimidines
diamino
preparation
analogical procedure
analogical
Prior art date
Application number
DK513771A
Other languages
English (en)
Other versions
DK132174B (da
Inventor
B Roth
A Stuart
T Paterson
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of DK132174B publication Critical patent/DK132174B/da
Application granted granted Critical
Publication of DK132174C publication Critical patent/DK132174C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK513771A 1970-10-22 1971-10-21 Analogifremgangsmade til fremstilling af 2,4-diamino-5-benzylpyrimidiner DK132174C (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB963871*[A GB1375162A (da) 1970-10-22 1970-10-22
GB963871 1971-04-16
GB4749171 1971-10-12

Publications (2)

Publication Number Publication Date
DK132174B DK132174B (da) 1975-11-03
DK132174C true DK132174C (da) 1976-03-29

Family

ID=27255400

Family Applications (1)

Application Number Title Priority Date Filing Date
DK513771A DK132174C (da) 1970-10-22 1971-10-21 Analogifremgangsmade til fremstilling af 2,4-diamino-5-benzylpyrimidiner

Country Status (20)

Country Link
JP (2) JPS5536662B1 (da)
AR (3) AR192588A1 (da)
AT (1) AT319948B (da)
BE (1) BE774281A (da)
BG (4) BG20365A3 (da)
CA (1) CA967158A (da)
CH (3) CH568301A5 (da)
DD (1) DD100877A5 (da)
DK (1) DK132174C (da)
ES (1) ES396219A1 (da)
FI (1) FI56175C (da)
FR (1) FR2111769B1 (da)
GB (1) GB1375162A (da)
IE (1) IE37452B1 (da)
IL (2) IL37984A (da)
LU (1) LU64129A1 (da)
MC (1) MC894A1 (da)
NL (1) NL175178C (da)
SE (2) SE384505B (da)
ZM (1) ZM14971A1 (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE792096A (fr) * 1971-12-01 1973-05-30 Hoffmann La Roche Nouvelles benzylpyrimidines
FR2397407A2 (fr) * 1977-07-11 1979-02-09 Dick Pierre Derives de 2,4-diamino pyrimidines et leur mise en solution en association avec des sulfamides
ZW9979A1 (en) * 1978-05-24 1980-12-24 Wellcome Found Benzylpyrimidine compositions
JPS61156909A (ja) * 1984-12-27 1986-07-16 Matsushita Electric Ind Co Ltd カレント・ミラ−回路
JPS62145907A (ja) * 1985-12-20 1987-06-30 Hitachi Ltd トランジスタ回路
BRPI0509258A8 (pt) 2004-03-26 2019-01-22 Astrazeneca Ab composto de 8-oxoadenina 9-substituída
JP2009542645A (ja) 2006-07-05 2009-12-03 アストラゼネカ・アクチエボラーグ Tlr7のモジュレーターとして作用する8−オキソアデニン誘導体
TW200831105A (en) 2006-12-14 2008-08-01 Astrazeneca Ab Novel compounds
EP2132209B8 (en) 2007-03-19 2014-04-16 AstraZeneca AB 9-substituted-8-oxo-adenine compounds as toll-like receptor (tlr7 ) modulators
JP5329444B2 (ja) 2007-03-19 2013-10-30 アストラゼネカ・アクチエボラーグ Toll様受容体(tlr7)モジュレーターとしての9−置換−8−オキソ−アデニン化合物
EP2138497A4 (en) 2007-03-20 2012-01-04 Dainippon Sumitomo Pharma Co NEW ADENINE CONNECTION
PE20091236A1 (es) * 2007-11-22 2009-09-16 Astrazeneca Ab Derivados de pirimidina como immunomoduladores de tlr7
UY31531A1 (es) 2007-12-17 2009-08-03 Sales derivadas de 8-oxoadenina composiciones farmacéuticas que las contienen y su uso en terapia como moduladores de receptor tipo toll (tlr)
GB0908772D0 (en) 2009-05-21 2009-07-01 Astrazeneca Ab New salts 756
AU2010250923A1 (en) 2009-05-21 2011-11-17 Astrazeneca Ab Novel pyrimidine derivatives and their use in the treatment of cancer and further diseases
CN103370317B (zh) 2010-12-16 2015-10-07 阿斯利康(瑞典)有限公司 可用于治疗的咪唑并[4,5-c]喹啉-1-基衍生物
WO2012080730A1 (en) 2010-12-17 2012-06-21 Astrazeneca Ab Purine derivatives
CA2871589C (en) 2012-05-18 2020-12-22 Seiji Hori Pyrimidine carboxylic acid derivatives and their use as tlr7 agonists

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE710100A (da) * 1967-02-02 1968-07-30
JPS511716A (ja) * 1974-06-25 1976-01-08 Toray Industries Horiesuterumaruchifuiramentono seiho

Also Published As

Publication number Publication date
JPS5536662B1 (da) 1980-09-22
AR192802A1 (es) 1973-03-14
NL7114494A (da) 1972-04-25
LU64129A1 (da) 1972-06-28
FI56175C (fi) 1979-12-10
SE409705B (sv) 1979-09-03
DD100877A5 (da) 1973-10-12
IE37452B1 (en) 1977-08-03
DK132174B (da) 1975-11-03
CA967158A (en) 1975-05-06
ES396219A1 (es) 1975-09-16
CH568302A5 (da) 1975-10-31
BG20365A3 (bg) 1975-11-05
FR2111769B1 (da) 1974-10-18
AR192803A1 (es) 1973-03-14
NL175178B (nl) 1984-05-01
AT319948B (de) 1975-01-10
JPS53135991A (en) 1978-11-28
FR2111769A1 (da) 1972-06-09
SE384505B (sv) 1976-05-10
IE37452L (en) 1972-04-22
BG20364A3 (bg) 1975-11-05
MC894A1 (fr) 1972-06-22
AR192588A1 (es) 1973-02-28
GB1375162A (da) 1974-11-27
CH568301A5 (da) 1975-10-31
IL45422A (en) 1976-03-31
IL37984A0 (en) 1971-12-29
BG21406A3 (bg) 1976-05-20
CH582681A5 (da) 1976-12-15
BE774281A (fr) 1972-04-21
FI56175B (fi) 1979-08-31
NL175178C (nl) 1984-10-01
ZM14971A1 (en) 1972-07-21
BG20797A3 (bg) 1975-12-20
IL37984A (en) 1976-03-31

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