DK132174B - Analogifremgangsmåde til fremstilling af 2,4-diamino-5-benzylpyrimider. - Google Patents

Analogifremgangsmåde til fremstilling af 2,4-diamino-5-benzylpyrimider.

Info

Publication number
DK132174B
DK132174B DK513771AA DK513771A DK132174B DK 132174 B DK132174 B DK 132174B DK 513771A A DK513771A A DK 513771AA DK 513771 A DK513771 A DK 513771A DK 132174 B DK132174 B DK 132174B
Authority
DK
Denmark
Prior art keywords
benzylpyrimides
diamino
preparation
analogous process
analogous
Prior art date
Application number
DK513771AA
Other languages
English (en)
Other versions
DK132174C (da
Inventor
B Roth
A Stuart
T Paterson
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of DK132174B publication Critical patent/DK132174B/da
Application granted granted Critical
Publication of DK132174C publication Critical patent/DK132174C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK513771A 1970-10-22 1971-10-21 Analogifremgangsmade til fremstilling af 2,4-diamino-5-benzylpyrimidiner DK132174C (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB963871*[A GB1375162A (da) 1970-10-22 1970-10-22
GB963871 1971-04-16
GB4749171 1971-10-12

Publications (2)

Publication Number Publication Date
DK132174B true DK132174B (da) 1975-11-03
DK132174C DK132174C (da) 1976-03-29

Family

ID=27255400

Family Applications (1)

Application Number Title Priority Date Filing Date
DK513771A DK132174C (da) 1970-10-22 1971-10-21 Analogifremgangsmade til fremstilling af 2,4-diamino-5-benzylpyrimidiner

Country Status (20)

Country Link
JP (2) JPS5536662B1 (da)
AR (3) AR192588A1 (da)
AT (1) AT319948B (da)
BE (1) BE774281A (da)
BG (4) BG20365A3 (da)
CA (1) CA967158A (da)
CH (3) CH568301A5 (da)
DD (1) DD100877A5 (da)
DK (1) DK132174C (da)
ES (1) ES396219A1 (da)
FI (1) FI56175C (da)
FR (1) FR2111769B1 (da)
GB (1) GB1375162A (da)
IE (1) IE37452B1 (da)
IL (2) IL37984A (da)
LU (1) LU64129A1 (da)
MC (1) MC894A1 (da)
NL (1) NL175178C (da)
SE (2) SE384505B (da)
ZM (1) ZM14971A1 (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE792096A (fr) * 1971-12-01 1973-05-30 Hoffmann La Roche Nouvelles benzylpyrimidines
FR2397407A2 (fr) * 1977-07-11 1979-02-09 Dick Pierre Derives de 2,4-diamino pyrimidines et leur mise en solution en association avec des sulfamides
MC1264A1 (fr) * 1978-05-24 1980-03-28 Wellcome Found Procede de preparation de benzylpyrimides et de medicaments contenant ces substances
JPS61156909A (ja) * 1984-12-27 1986-07-16 Matsushita Electric Ind Co Ltd カレント・ミラ−回路
JPS62145907A (ja) * 1985-12-20 1987-06-30 Hitachi Ltd トランジスタ回路
US8012964B2 (en) 2004-03-26 2011-09-06 Dainippon Sumitomo Pharma Co., Ltd. 9-substituted 8-oxoadenine compound
WO2008004948A1 (en) 2006-07-05 2008-01-10 Astrazeneca Ab 8-oxoadenine derivatives acting as modulators of tlr7
TW200831105A (en) 2006-12-14 2008-08-01 Astrazeneca Ab Novel compounds
JP5329444B2 (ja) 2007-03-19 2013-10-30 アストラゼネカ・アクチエボラーグ Toll様受容体(tlr7)モジュレーターとしての9−置換−8−オキソ−アデニン化合物
SI2132209T1 (sl) 2007-03-19 2014-05-30 Astrazeneca Ab Spojine 9-substituiranega-8-okso-adenina, kot modulatorji Toll-like receptorja (TLR7)
EP2138497A4 (en) 2007-03-20 2012-01-04 Dainippon Sumitomo Pharma Co NEW ADENINE CONNECTION
PE20091236A1 (es) * 2007-11-22 2009-09-16 Astrazeneca Ab Derivados de pirimidina como immunomoduladores de tlr7
PE20091156A1 (es) 2007-12-17 2009-09-03 Astrazeneca Ab Sales de (3-{[[3-(6-amino-2-butoxi-8-oxo-7,8-dihidro-9h-purin-9-il)propil](3-morfolin-4-ilpropil)amino]metil}fenil)acetato de metilo
GB0908772D0 (en) 2009-05-21 2009-07-01 Astrazeneca Ab New salts 756
BRPI1010937A2 (pt) 2009-05-21 2019-09-24 Astrazeneca Ab composto, uso de um composto, e, método para tratar câncer
WO2012080728A1 (en) 2010-12-16 2012-06-21 Astrazeneca Ab Imidazo [4, 5 -c] quinolin- 1 -yl derivative useful in therapy
ES2627433T3 (es) 2010-12-17 2017-07-28 Sumitomo Dainippon Pharma Co., Ltd. Derivados de purina
EP2850067B1 (en) 2012-05-18 2017-08-16 Sumitomo Dainippon Pharma Co., Ltd. Carboxylic acid compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE710100A (da) * 1967-02-02 1968-07-30
JPS511716A (ja) * 1974-06-25 1976-01-08 Toray Industries Horiesuterumaruchifuiramentono seiho

Also Published As

Publication number Publication date
IL45422A (en) 1976-03-31
CA967158A (en) 1975-05-06
FR2111769A1 (da) 1972-06-09
IL37984A (en) 1976-03-31
SE409705B (sv) 1979-09-03
BG20365A3 (bg) 1975-11-05
NL175178B (nl) 1984-05-01
DD100877A5 (da) 1973-10-12
JPS53135991A (en) 1978-11-28
CH568302A5 (da) 1975-10-31
BE774281A (fr) 1972-04-21
AR192588A1 (es) 1973-02-28
NL7114494A (da) 1972-04-25
AT319948B (de) 1975-01-10
BG20364A3 (bg) 1975-11-05
ES396219A1 (es) 1975-09-16
IE37452L (en) 1972-04-22
FR2111769B1 (da) 1974-10-18
ZM14971A1 (en) 1972-07-21
BG21406A3 (bg) 1976-05-20
DK132174C (da) 1976-03-29
CH568301A5 (da) 1975-10-31
AR192803A1 (es) 1973-03-14
FI56175C (fi) 1979-12-10
SE384505B (sv) 1976-05-10
GB1375162A (da) 1974-11-27
JPS5536662B1 (da) 1980-09-22
AR192802A1 (es) 1973-03-14
CH582681A5 (da) 1976-12-15
IL37984A0 (en) 1971-12-29
IE37452B1 (en) 1977-08-03
LU64129A1 (da) 1972-06-28
FI56175B (fi) 1979-08-31
NL175178C (nl) 1984-10-01
MC894A1 (fr) 1972-06-22
BG20797A3 (bg) 1975-12-20

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