DK1343523T3 - Anvendelse af aktiveret faktor VII til behandling af thrombolytisk terapi-inducerede alvorlige blödninger - Google Patents

Anvendelse af aktiveret faktor VII til behandling af thrombolytisk terapi-inducerede alvorlige blödninger

Info

Publication number
DK1343523T3
DK1343523T3 DK01995705T DK01995705T DK1343523T3 DK 1343523 T3 DK1343523 T3 DK 1343523T3 DK 01995705 T DK01995705 T DK 01995705T DK 01995705 T DK01995705 T DK 01995705T DK 1343523 T3 DK1343523 T3 DK 1343523T3
Authority
DK
Denmark
Prior art keywords
treatment
factor vii
activated factor
thrombolytic therapy
severe bleeding
Prior art date
Application number
DK01995705T
Other languages
Danish (da)
English (en)
Inventor
Gerhard Heusel
Cord Skamira
Jean Marie Stassen
Wolfgang Wienen
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Application granted granted Critical
Publication of DK1343523T3 publication Critical patent/DK1343523T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482Serine endopeptidases (3.4.21)
    • A61K38/4846Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DK01995705T 2000-12-21 2001-12-20 Anvendelse af aktiveret faktor VII til behandling af thrombolytisk terapi-inducerede alvorlige blödninger DK1343523T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00128252A EP1216709A1 (en) 2000-12-21 2000-12-21 Use of activated coagulation factor VII for treating thrombolytic therapy-induced major bleedings
PCT/EP2001/015132 WO2002049665A2 (en) 2000-12-21 2001-12-20 Use of activated coagulation factor vii for treating thrombolytic therapy-induced major bleedings

Publications (1)

Publication Number Publication Date
DK1343523T3 true DK1343523T3 (da) 2007-04-10

Family

ID=8170769

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01995705T DK1343523T3 (da) 2000-12-21 2001-12-20 Anvendelse af aktiveret faktor VII til behandling af thrombolytisk terapi-inducerede alvorlige blödninger

Country Status (25)

Country Link
US (2) US20040087502A1 (cs)
EP (2) EP1216709A1 (cs)
JP (1) JP2004516273A (cs)
KR (1) KR20030063454A (cs)
CN (1) CN1482919A (cs)
AT (1) ATE353666T1 (cs)
AU (2) AU2638602A (cs)
BR (1) BR0116151A (cs)
CA (1) CA2431986A1 (cs)
CY (1) CY1106363T1 (cs)
CZ (1) CZ300670B6 (cs)
DE (1) DE60126650T2 (cs)
DK (1) DK1343523T3 (cs)
EC (1) ECSP034647A (cs)
ES (1) ES2280429T3 (cs)
HU (1) HUP0302574A3 (cs)
IL (1) IL155886A0 (cs)
MX (1) MXPA03005641A (cs)
NZ (1) NZ549850A (cs)
PL (1) PL205878B1 (cs)
PT (1) PT1343523E (cs)
RU (1) RU2286796C2 (cs)
SI (1) SI1343523T1 (cs)
WO (1) WO2002049665A2 (cs)
ZA (1) ZA200304140B (cs)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2570330A1 (en) * 2004-06-21 2005-12-29 Novo Nordisk Health Care A/S Use of factor viia or factor viia equivalents for preventing or attenuating haemorrhage growth, and/or oedema generation following intracerebral haemorrhage (ich)
RU2396086C2 (ru) * 2004-09-10 2010-08-10 Фармаоригин Апс Способы лечения трахеального, бронхиального или альвеолярного кровотечения или кровохарканья
EP1906993A2 (en) * 2005-07-15 2008-04-09 Novo Nordisk Health Care AG USE OF FACTOR VIIa OR FACTOR VIIa EQUIVALENTS FOR PREVENTING OR ATTENUATING HAEMORRHAGE GROWTH, AND/OR OEDEMA GENERATION FOLLOWING INTRACEREBRAL HAEMORRHAGE (ICH) IN PATIENTS TREATED WITH ANTIPLATELET THERAPY
CN101918025A (zh) 2008-01-18 2010-12-15 诺沃-诺迪斯克保健股份有限公司 因子Ⅶa或因子Ⅶa等同物用于防止或减弱选择的脑内出血患者亚群在脑内出血(ICH)后出血增多和/或水肿形成的用途
RU2552339C1 (ru) * 2014-02-19 2015-06-10 Общество с ограниченной ответственностью фирма "Технология-Стандарт" Способ профилактики кровотечений, вызванных применением стрептокиназы, в эксперименте

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4382082A (en) * 1980-12-18 1983-05-03 Uop Inc. Recovery of cobalt values by absorption from ammoniacal solution
ZA862768B (en) * 1985-04-17 1986-12-30 Zymogenetics Inc Expression of factor vii and ix activities in mammalian cells
US5374617A (en) * 1992-05-13 1994-12-20 Oklahoma Medical Research Foundation Treatment of bleeding with modified tissue factor in combination with FVIIa
US5846517A (en) * 1996-09-11 1998-12-08 Imarx Pharmaceutical Corp. Methods for diagnostic imaging using a renal contrast agent and a vasodilator
WO1998058661A1 (en) * 1997-06-23 1998-12-30 Novo Nordisk A/S Use of fviia for the treatment of bleedings in patients with a normal blood clotting cascade and normal platelet function

Also Published As

Publication number Publication date
HUP0302574A2 (hu) 2003-10-28
RU2286796C2 (ru) 2006-11-10
NZ549850A (en) 2008-04-30
CA2431986A1 (en) 2002-06-27
PT1343523E (pt) 2007-03-30
BR0116151A (pt) 2003-10-21
EP1343523A2 (en) 2003-09-17
HUP0302574A3 (en) 2010-01-28
US20040087502A1 (en) 2004-05-06
DE60126650T2 (de) 2007-10-31
KR20030063454A (ko) 2003-07-28
MXPA03005641A (es) 2004-12-03
IL155886A0 (en) 2003-12-23
EP1343523B1 (en) 2007-02-14
ECSP034647A (es) 2003-07-25
WO2002049665A2 (en) 2002-06-27
EP1216709A1 (en) 2002-06-26
PL361855A1 (en) 2004-10-04
DE60126650D1 (de) 2007-03-29
SI1343523T1 (sl) 2007-04-30
US20080286259A1 (en) 2008-11-20
WO2002049665A3 (en) 2002-09-26
PL205878B1 (pl) 2010-06-30
AU2638602A (en) 2002-07-01
CY1106363T1 (el) 2011-10-12
AU2002226386B2 (en) 2005-12-22
JP2004516273A (ja) 2004-06-03
CN1482919A (zh) 2004-03-17
ES2280429T3 (es) 2007-09-16
ATE353666T1 (de) 2007-03-15
ZA200304140B (en) 2004-04-22
CZ20031743A3 (cs) 2003-11-12
CZ300670B6 (cs) 2009-07-15
RU2003122362A (ru) 2005-02-10

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