DK1352966T3 - Fremgangsmåde til fremstilling af L-aminosyrer - Google Patents

Fremgangsmåde til fremstilling af L-aminosyrer

Info

Publication number
DK1352966T3
DK1352966T3 DK03006936T DK03006936T DK1352966T3 DK 1352966 T3 DK1352966 T3 DK 1352966T3 DK 03006936 T DK03006936 T DK 03006936T DK 03006936 T DK03006936 T DK 03006936T DK 1352966 T3 DK1352966 T3 DK 1352966T3
Authority
DK
Denmark
Prior art keywords
amino acid
medium
preparation
amino acids
microorganism
Prior art date
Application number
DK03006936T
Other languages
English (en)
Inventor
Tsuyoshi Nakamatsu
Yoshihiko Hara
Hiroshi Izui
Takahiro Asano
Yasuyuki Watanabe
Original Assignee
Ajinomoto Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk
Application granted granted Critical
Publication of DK1352966T3 publication Critical patent/DK1352966T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/14Glutamic acid; Glutamine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
DK03006936T 2002-03-27 2003-03-26 Fremgangsmåde til fremstilling af L-aminosyrer DK1352966T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2002088668A JP3932945B2 (ja) 2002-03-27 2002-03-27 L−アミノ酸の製造法

Publications (1)

Publication Number Publication Date
DK1352966T3 true DK1352966T3 (da) 2005-08-08

Family

ID=28449463

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03006936T DK1352966T3 (da) 2002-03-27 2003-03-26 Fremgangsmåde til fremstilling af L-aminosyrer

Country Status (16)

Country Link
US (2) US7037690B2 (da)
EP (1) EP1352966B1 (da)
JP (1) JP3932945B2 (da)
KR (1) KR100949048B1 (da)
CN (1) CN100529094C (da)
AT (1) ATE299945T1 (da)
AU (1) AU2003202509B2 (da)
BR (1) BR0300978B1 (da)
DE (1) DE60301031T2 (da)
DK (1) DK1352966T3 (da)
ES (1) ES2243826T3 (da)
MY (1) MY130526A (da)
PE (1) PE20031014A1 (da)
PL (1) PL359383A1 (da)
RU (1) RU2307165C2 (da)
TW (1) TWI308594B (da)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU756507B2 (en) * 1998-03-18 2003-01-16 Ajinomoto Co., Inc. L-glutamic acid-producing bacterium and method for producing L-glutamic acid
JP4427878B2 (ja) 1999-08-20 2010-03-10 味の素株式会社 析出を伴う発酵法によるl−グルタミン酸の製造法
JP4599726B2 (ja) 2001-02-20 2010-12-15 味の素株式会社 L−グルタミン酸の製造法
JP3932945B2 (ja) * 2002-03-27 2007-06-20 味の素株式会社 L−アミノ酸の製造法
JP2004166595A (ja) 2002-11-20 2004-06-17 Ajinomoto Co Inc メチロトローフを用いたl−アミノ酸の製造法
EP1624069A4 (en) 2003-05-07 2011-06-29 Ajinomoto Kk PROCESS FOR THE PREPARATION OF L-GLUTAMINE ACID
JPWO2004111258A1 (ja) 2003-06-10 2006-07-27 味の素株式会社 L−グルタミン酸の製造法
DE102004003410A1 (de) * 2004-01-23 2005-08-25 Degussa Ag Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae
DE102004014280A1 (de) * 2004-03-22 2005-10-27 Degussa Ag Verfahren zur Herstellung von optisch aktiven Aminosäuren mittels eines Ganzzellkatalysators
JP4984423B2 (ja) * 2004-04-26 2012-07-25 味の素株式会社 L−アミノ酸生産菌及びl−アミノ酸の製造法
US7300776B2 (en) * 2004-04-26 2007-11-27 Ajinomoto Co., Inc. L-amino acid-producing bacterium and a method for producing L-amino acid
RU2004124226A (ru) 2004-08-10 2006-01-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) Использование фосфокетолазы для продукции полезных метаболитов
US7501282B2 (en) 2005-02-25 2009-03-10 Ajinomoto Co., Inc. Plasmid autonomously replicable in Enterobacteriaceae family
JP2009118740A (ja) * 2006-03-03 2009-06-04 Ajinomoto Co Inc L−アミノ酸の製造法
KR100885616B1 (ko) * 2006-06-26 2009-02-24 씨제이제일제당 (주) 글리세롤을 이용한 아미노산의 생산 방법
JP2010041920A (ja) 2006-12-19 2010-02-25 Ajinomoto Co Inc L−アミノ酸の製造法
WO2008090770A1 (ja) 2007-01-22 2008-07-31 Ajinomoto Co., Inc. L-アミノ酸を生産する微生物及びl-アミノ酸の製造法
JP2010088301A (ja) 2007-02-01 2010-04-22 Ajinomoto Co Inc L−アミノ酸の製造法
JP2010130899A (ja) 2007-03-14 2010-06-17 Ajinomoto Co Inc L−グルタミン酸系アミノ酸生産微生物及びアミノ酸の製造法
JP5218400B2 (ja) 2007-04-17 2013-06-26 味の素株式会社 カルボキシル基を有する酸性物質の製造法
RU2395579C2 (ru) 2007-12-21 2010-07-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТЫ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ, ПРИНАДЛЕЖАЩЕЙ К РОДУ Escherichia
JP5488467B2 (ja) 2008-09-05 2014-05-14 味の素株式会社 L−アミノ酸生産菌及びl−アミノ酸の製造法
CN102177246B (zh) 2008-09-08 2015-02-11 味之素株式会社 生产l-氨基酸的微生物和l-氨基酸的生产方法
US8647642B2 (en) 2008-09-18 2014-02-11 Aviex Technologies, Llc Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment
BRPI0914521A2 (pt) * 2008-10-27 2016-07-26 Butamax Advanced Biofuels Llc célula hospedeira microbiana recombinante, método de aumento da produção de isobutanol e método de produção de isobutanol
AP3766A (en) * 2009-07-09 2016-07-31 Du Pont Engineered microorganisms with enhanced fermentation activity
BR112013016373B1 (pt) 2011-11-11 2021-05-18 Ajinomoto Co., Inc método para produzir uma substância alvo
US20140322779A1 (en) * 2011-11-11 2014-10-30 Genomatica, Inc. Eukaryotic organisms and methods for increasing the availability of cytosolic acetyl-coa, and for the producing 1,3-butanediol
DK2811028T3 (da) 2013-06-03 2017-05-01 Evonik Degussa Gmbh Fremgangsmåde til fremstilling af L-valin under anvendelse af rekombinante corynebakterier indeholdende det ved hjælp af propionat inducerbare ilvBN-operon
JP2016165225A (ja) 2013-07-09 2016-09-15 味の素株式会社 有用物質の製造方法
JP2016192903A (ja) * 2013-09-17 2016-11-17 味の素株式会社 海藻由来バイオマスからのl−アミノ酸の製造方法
EP2886651B1 (en) 2013-10-21 2018-08-22 Ajinomoto Co., Inc. Method for producing l-amino acid
KR101835173B1 (ko) * 2014-06-23 2018-03-07 씨제이제일제당 (주) L-트립토판 생산능을 갖는 에스케리키아속 미생물 및 이를 이용한 l-트립토판의 제조 방법
US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
JP7066977B2 (ja) 2017-04-03 2022-05-16 味の素株式会社 L-アミノ酸の製造法
US11459574B2 (en) 2018-05-01 2022-10-04 Research Institute Of Innovative Technology For The Earth Transformant having Entner-Doudoroff pathway and production method for organic compound using same
WO2020071538A1 (en) 2018-10-05 2020-04-09 Ajinomoto Co., Inc. Method for producing target substance by bacterial fermentation
WO2020171227A1 (en) 2019-02-22 2020-08-27 Ajinomoto Co., Inc. METHOD FOR PRODUCING L-AMINO ACIDS USING A BACTERIUM BELONGING TO THE FAMILY Enterobacteriaceae HAVING OVEREXPRESSED ydiJ GENE
JP7524909B2 (ja) 2019-04-05 2024-07-30 味の素株式会社 L-アミノ酸の製造方法
JP7655312B2 (ja) 2019-09-25 2025-04-02 味の素株式会社 細菌の発酵によるl-アミノ酸の製造方法
CN113278568B (zh) * 2020-05-27 2022-10-21 安徽华恒生物科技股份有限公司 生产l-缬氨酸的重组大肠杆菌及其应用
US20240117393A1 (en) 2022-09-30 2024-04-11 Ajinomoto Co., Inc. Method for producing l-amino acid
CN116536292A (zh) * 2022-11-04 2023-08-04 吉林梅花氨基酸有限责任公司 磷酸葡萄糖酸脱水酶突变体及其应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU1694643A1 (ru) * 1987-11-26 1991-11-30 Всесоюзный научно-исследовательский институт генетики и селекции промышленных микроорганизмов Штамм бактерий ЕSснеRIснIа coLI - продуцент L-треонина
JPH07155184A (ja) * 1993-12-08 1995-06-20 Ajinomoto Co Inc 発酵法によるl−リジンの製造法
GB9405629D0 (en) * 1994-03-22 1994-05-11 Whitbread & Co Ltd Recombinant DNA for use in yeast
AU756507B2 (en) * 1998-03-18 2003-01-16 Ajinomoto Co., Inc. L-glutamic acid-producing bacterium and method for producing L-glutamic acid
AU761990B2 (en) 1998-10-19 2003-06-12 Ajinomoto Co., Inc. L-glutamic acid producing bacterium and process for producing L-glutamic acid
JP2003180355A (ja) 1999-07-02 2003-07-02 Ajinomoto Co Inc L−アミノ酸の製造法
JP2003159092A (ja) 1999-07-02 2003-06-03 Ajinomoto Co Inc L−アミノ酸の製造法
JP4427878B2 (ja) 1999-08-20 2010-03-10 味の素株式会社 析出を伴う発酵法によるl−グルタミン酸の製造法
KR20020073153A (ko) 1999-12-24 2002-09-19 아지노모토 가부시키가이샤 L-아미노산의 제조법 및 신규 유전자
JP2002238592A (ja) * 2001-02-20 2002-08-27 Ajinomoto Co Inc L−グルタミン酸の製造法
DE10135051A1 (de) * 2001-07-18 2003-02-06 Degussa Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae
JP3932945B2 (ja) * 2002-03-27 2007-06-20 味の素株式会社 L−アミノ酸の製造法
JP2004166595A (ja) * 2002-11-20 2004-06-17 Ajinomoto Co Inc メチロトローフを用いたl−アミノ酸の製造法

Also Published As

Publication number Publication date
DE60301031T2 (de) 2006-06-01
PE20031014A1 (es) 2004-02-05
KR100949048B1 (ko) 2010-03-25
DE60301031D1 (de) 2005-08-25
EP1352966B1 (en) 2005-07-20
TW200306352A (en) 2003-11-16
EP1352966A2 (en) 2003-10-15
BR0300978A (pt) 2004-09-08
US20030219882A1 (en) 2003-11-27
CN1446920A (zh) 2003-10-08
JP3932945B2 (ja) 2007-06-20
CN100529094C (zh) 2009-08-19
US7037690B2 (en) 2006-05-02
BR0300978B1 (pt) 2014-02-25
KR20030078036A (ko) 2003-10-04
JP2003274988A (ja) 2003-09-30
MY130526A (en) 2007-06-29
ES2243826T3 (es) 2005-12-01
RU2307165C2 (ru) 2007-09-27
EP1352966A3 (en) 2004-01-21
US7432085B2 (en) 2008-10-07
AU2003202509A1 (en) 2003-10-16
AU2003202509B2 (en) 2007-12-13
TWI308594B (en) 2009-04-11
US20060115878A1 (en) 2006-06-01
PL359383A1 (en) 2003-10-06
ATE299945T1 (de) 2005-08-15

Similar Documents

Publication Publication Date Title
DK1352966T3 (da) Fremgangsmåde til fremstilling af L-aminosyrer
BR0106255A (pt) Método papa produzir uma substância alvo pela utilização de um microorganismo
DK1664318T3 (da) L-aminosyre-producerende mikroorganisme og fremgangsmåde til fremstilling af L-aminosyre
DK1651758T3 (da) Fremgangsmåde tl fremstilling af L-lysin eller L-threonin ved anvendelse af Escherichia bakterier med svækket æblesyreenzymaktivitet
DE60144205D1 (de) Verfahren zur Herstellung von L-Lysin unter Verwendung von Escherichia coli
ATE554159T1 (de) Zur produktion von l-aminosäure fähiger mikroorganismus und verfahren zur produktion von l-aminosäure
BRPI0401918A (pt) Método para produzir uma substância de marcação, e, bactéria
ID24398A (id) Metode untuk menghasilkan asam l-amino
EP0976829A3 (en) Protein-deamidating enzyme, gene encoding the same, production process therefor, and use thereof
ATE486949T1 (de) Verfahren zur herstellung von n- acetylneuraminsäure
BR0016656A (pt) Bactéria corineforme, método para produzir um l-aminoácido, e, dna
JP2002249390A5 (da)
RU2002123836A (ru) Способ получения целевого вещества
ATE415470T1 (de) Herstellungsverfahren für iturin a und dessen homologe
RU2003126289A (ru) Способ получения l-аминокислот с использованием бактерий семейства enterobacteriaceae, содержащих инактивированный оперон nir
DE60032046D1 (de) Verfahren zur Herstellung von L-Glutaminsäure
BR0011672A (pt) Bactéria corineforme, processo para produzir l-lisina, e, dna
DE60311463D1 (de) Ausflockung mit zweiwertigem salz
TW200716755A (en) A method for producing amino acids
ATE279527T1 (de) Verfahren zur herstellung von l-2- aminoadipinsäure
JPS56144088A (en) Acylpolyamine amidohydrolase
MX9707921A (es) Procedimiento para la produccion de l-aminoacido mediante fermentacion.