BRPI0401918A - Método para produzir uma substância de marcação, e, bactéria - Google Patents
Método para produzir uma substância de marcação, e, bactériaInfo
- Publication number
- BRPI0401918A BRPI0401918A BR0401918-0A BRPI0401918A BRPI0401918A BR PI0401918 A BRPI0401918 A BR PI0401918A BR PI0401918 A BRPI0401918 A BR PI0401918A BR PI0401918 A BRPI0401918 A BR PI0401918A
- Authority
- BR
- Brazil
- Prior art keywords
- target substance
- bacterium
- medium
- producing
- marking substance
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
- C12N15/69—Increasing the copy number of the vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
- C12P13/222—Phenylalanine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Plant Pathology (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicinal Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
"MéTODO PARA PRODUZIR UMA SUBSTâNCIA DE MARCAçãO, E, BACTéRIA". Uma substância de marcação é produzida por cultivo de uma bactéria que tem a capacidade de produzir a substância de marcação em um meio para provocar o acúmulo de referida substância de marcação no meio e coletar a substância de marcação do meio, em que a bactéria é modificada como um sistema para captação de um subproduto da substância de marcação ou um substrato para um sistema de biossíntese da substância de marcação na célula bacteriana.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003161181 | 2003-06-05 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BRPI0401918A true BRPI0401918A (pt) | 2005-06-28 |
| BRPI0401918B1 BRPI0401918B1 (pt) | 2014-12-09 |
Family
ID=33157205
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0401918-0A BRPI0401918B1 (pt) | 2003-06-05 | 2004-06-04 | Método para produzir uma substância alvo, e, Escherichia coli |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7335496B2 (pt) |
| EP (1) | EP1484410B1 (pt) |
| JP (1) | JP5287904B2 (pt) |
| KR (1) | KR101110580B1 (pt) |
| CN (1) | CN100564516C (pt) |
| AT (1) | ATE531803T1 (pt) |
| BR (1) | BRPI0401918B1 (pt) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR0304860A (pt) * | 2002-11-11 | 2004-08-31 | Ajinomoto Kk | Método para produzir uma substância alvo pela utilização de uma-bactéria pertencente ao gênero escherichia |
| JP4380305B2 (ja) * | 2003-11-21 | 2009-12-09 | 味の素株式会社 | 発酵法によるl−アミノ酸の製造法 |
| US7344874B2 (en) * | 2004-03-04 | 2008-03-18 | Ajinomoto Co., Inc. | L-glutamic acid-producing microorganism and a method for producing L-glutamic acid |
| US7482140B2 (en) * | 2004-06-15 | 2009-01-27 | Ajinomoto Co., Inc. | L-tyrosine-producing bacterium and a method for producing L-tyrosine |
| US7205132B2 (en) * | 2004-09-10 | 2007-04-17 | Ajinomoto Co., Inc. | L-glutamic acid-producing microorganism and a method for producing L-glutamic acid |
| EP2368905A3 (en) * | 2004-12-17 | 2012-08-29 | Metanomics GmbH | Process for the control of production of fine chemicals |
| US7794989B2 (en) | 2004-12-28 | 2010-09-14 | Ajinomoto Co., Inc. | L-glutamic acid-producing microorganism and a method for producing L-glutamic acid |
| WO2006078039A1 (en) | 2005-01-18 | 2006-07-27 | Ajinomoto Co., Inc. | L-amino acid producing microorganism and a method for producing l-amino acid |
| US20070004014A1 (en) * | 2005-06-29 | 2007-01-04 | Yuichiro Tsuji | Method for producing l-threonine |
| JP2008283863A (ja) | 2005-08-26 | 2008-11-27 | Ajinomoto Co Inc | L−アミノ酸生産菌及びl−アミノ酸の製造方法 |
| JP2010017082A (ja) | 2006-10-10 | 2010-01-28 | Ajinomoto Co Inc | L−アミノ酸の製造法 |
| JP2010110216A (ja) | 2007-02-20 | 2010-05-20 | Ajinomoto Co Inc | L−アミノ酸または核酸の製造方法 |
| JP2011067095A (ja) | 2008-01-10 | 2011-04-07 | Ajinomoto Co Inc | 発酵法による目的物質の製造法 |
| JP5526785B2 (ja) | 2008-01-23 | 2014-06-18 | 味の素株式会社 | L−アミノ酸の製造法 |
| WO2010137130A1 (ja) | 2009-05-27 | 2010-12-02 | 味の素株式会社 | 有機酸の製造方法 |
| JPWO2011013707A1 (ja) | 2009-07-29 | 2013-01-10 | 味の素株式会社 | L−アミノ酸の製造法 |
| JP2012223092A (ja) | 2009-08-28 | 2012-11-15 | Ajinomoto Co Inc | L−アミノ酸の製造法 |
| JP2013013329A (ja) | 2009-11-06 | 2013-01-24 | Ajinomoto Co Inc | L−アミノ酸の製造法 |
| BR112015007916B1 (pt) | 2013-05-13 | 2023-04-04 | Ajinomoto Co., Inc | Método para produzir l-aminoácido |
| CN106459857B (zh) | 2013-10-02 | 2019-04-19 | 味之素株式会社 | 氨控制装置及氨控制方法 |
| JP6459962B2 (ja) | 2013-10-21 | 2019-01-30 | 味の素株式会社 | L−アミノ酸の製造法 |
| EP3061828B1 (en) | 2013-10-23 | 2024-08-28 | Ajinomoto Co., Inc. | Method for producing target substance |
| WO2016136508A1 (ja) * | 2015-02-23 | 2016-09-01 | 国立大学法人静岡大学 | 2-アザ-8オキソヒポキサンチンの製造方法 |
| RU2015114955A (ru) | 2015-04-22 | 2016-11-10 | Аджиномото Ко., Инк. | Способ получения L-изолейцина с использованием бактерии семейства Enterobacteriaceae, в которой сверхэкспрессирован ген cycA |
| JP7066977B2 (ja) | 2017-04-03 | 2022-05-16 | 味の素株式会社 | L-アミノ酸の製造法 |
| EP3861109A1 (en) | 2018-10-05 | 2021-08-11 | Ajinomoto Co., Inc. | Method for producing target substance by bacterial fermentation |
| CN114369559B (zh) * | 2020-10-15 | 2024-05-03 | 宁夏伊品生物科技股份有限公司 | 一种产l-氨基酸的重组菌株及其构建方法与应用 |
| CN114540261B (zh) * | 2020-11-24 | 2024-02-02 | 北京化工大学 | 一种产氨基己二酸的基因工程菌 |
| EP4505875A1 (en) | 2022-04-04 | 2025-02-12 | Ajinomoto Co., Inc. | Method for controlling parasitic plants |
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| US5614396A (en) * | 1990-06-14 | 1997-03-25 | Baylor College Of Medicine | Methods for the genetic modification of endogenous genes in animal cells by homologous recombination |
| CA2090126C (en) * | 1990-08-02 | 2002-10-22 | John W. Schrader | Methods for the production of proteins with a desired function |
| DE69133557D1 (de) * | 1990-08-29 | 2007-03-15 | Pharming Intellectual Pty Bv | Homologe rekombination in säugetier-zellen |
| WO1993019660A1 (en) * | 1992-04-03 | 1993-10-14 | Baylor College Of Medicine | Gene therapy using the intestine |
| US5792751A (en) * | 1992-04-13 | 1998-08-11 | Baylor College Of Medicine | Tranformation of cells associated with fluid spaces |
| US5645986A (en) * | 1992-05-13 | 1997-07-08 | Board Of Reagents, The University Of Texas System | Therapy and diagnosis of conditions related to telomere length and/or telomerase activity |
| US5645829A (en) * | 1993-06-18 | 1997-07-08 | Beth Israel Hospital Association | Mesothelial cell gene therapy |
| PL180300B1 (pl) | 1993-10-08 | 2001-01-31 | Lonza Ag | wektor zawierajacy taki fragment DNA, a takze mikroorganizmzawierajacy wskazany fragment DNA badz wektor oraz biotechnologiczny sposób wytwarzania L-karnityny PL PL PL PL PL |
| US5665350A (en) * | 1994-11-23 | 1997-09-09 | University Of Massachusetts Medical Center | Cell cycle dependent transplantation and ex vivo gene therapy |
| US5780296A (en) * | 1995-01-17 | 1998-07-14 | Thomas Jefferson University | Compositions and methods to promote homologous recombination in eukaryotic cells and organisms |
| US5824655A (en) * | 1995-02-15 | 1998-10-20 | The University Of Utah | Anti-transforming growth factor-β gene therapy |
| US5656638A (en) * | 1995-04-18 | 1997-08-12 | Geron Corporation | Telomerase inhibitors |
| US5703116A (en) * | 1995-04-18 | 1997-12-30 | Geron Corporation | Telomerase Inhibitors |
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| AU705616B2 (en) * | 1995-04-21 | 1999-05-27 | Cell Genesys, Inc. | Generation of large genomic DNA deletions |
| US5756283A (en) * | 1995-06-05 | 1998-05-26 | The Trustees Of The University Of Pennsylvania | Method for improved production of recombinant adeno-associated viruses for gene therapy |
| US5776744A (en) * | 1995-06-07 | 1998-07-07 | Yale University | Methods and compositions for effecting homologous recombination |
| DE19523279A1 (de) | 1995-06-27 | 1997-01-09 | Forschungszentrum Juelich Gmbh | Verfahren zur mikrobiellen Herstellung von Aminosäuren mittels rekombinanter Mikroorganismen mit erhöhter Sekretionsrate |
| US5770613A (en) * | 1995-09-29 | 1998-06-23 | Geron Corporation | Telomerase inhibitors |
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| EP0861321B1 (en) * | 1995-10-13 | 2006-05-31 | President And Fellows Of Harvard College | Phosphopantetheinyl transferases and uses thereof |
| DE19548222A1 (de) | 1995-12-22 | 1997-06-26 | Forschungszentrum Juelich Gmbh | Verfahren zur mikrobiellen Herstellung von Aminosäuren durch gesteigerte Aktivität von Exportcarriern |
| US5874304A (en) * | 1996-01-18 | 1999-02-23 | University Of Florida Research Foundation, Inc. | Humanized green fluorescent protein genes and methods |
| DE19644566A1 (de) * | 1996-10-26 | 1998-04-30 | Forschungszentrum Juelich Gmbh | Mikrobielle Herstellung von Substanzen aus dem aromatischen Stoffwechsel / I |
| DE19644567A1 (de) | 1996-10-26 | 1998-04-30 | Forschungszentrum Juelich Gmbh | Mikrobielle Herstellung von Substanzen aus dem aromatischen Stoffwechsel / II |
| EP0839909A1 (en) | 1996-10-29 | 1998-05-06 | Rijksuniversiteit te Groningen | Nucleic acid sequences encoding citrate transporter proteins |
| US5925544A (en) * | 1996-11-18 | 1999-07-20 | Novo Nordisk A/S | Method of homologous recombination followed by in vivo selection of DNA amplification |
| US5830698A (en) * | 1997-03-14 | 1998-11-03 | Idec Pharmaceuticals Corporation | Method for integrating genes at specific sites in mammalian cells via homologous recombination and vectors for accomplishing the same |
| US5948653A (en) * | 1997-03-21 | 1999-09-07 | Pati; Sushma | Sequence alterations using homologous recombination |
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| MY121380A (en) * | 1998-04-13 | 2006-01-28 | Univ Georgia | Pyruvate carboxylase overexpression for enhanced production of oxaloacetate-derived biochemicals in microbial cells |
| US6027488A (en) * | 1998-06-03 | 2000-02-22 | Genetronics, Inc. | Flow-through electroporation system for ex vivo gene therapy |
| RU2144564C1 (ru) * | 1998-10-13 | 2000-01-20 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" | ФРАГМЕНТ ДНК rhtB, КОДИРУЮЩИЙ СИНТЕЗ БЕЛКА RhtB, ПРИДАЮЩЕГО УСТОЙЧИВОСТЬ К L-ГОМОСЕРИНУ БАКТЕРИЯМ ESCHERICHIA COLI, И СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТ |
| JP2002293797A (ja) | 1998-12-18 | 2002-10-09 | Ajinomoto Co Inc | Abcトランスポーター及びそれをコードする遺伝子 |
| RU2148642C1 (ru) * | 1998-12-23 | 2000-05-10 | ЗАО "Научно-исследовательский институт АДЖИНОМОТО-Генетика" (ЗАО "АГРИ") | Фрагмент днк rhtc, кодирующий синтез белка rhtc, придающего повышенную устойчивость к l-треонину бактериям escherichia coli, и способ получения l-аминокислоты |
| JP4061769B2 (ja) | 1999-03-25 | 2008-03-19 | 味の素株式会社 | L−グルタミン酸の製造法 |
| EP1197555B1 (en) | 1999-07-02 | 2006-04-05 | Ajinomoto Co., Inc. | Dna encoding sucrose pts enzyme ii |
| JP2003159065A (ja) | 1999-07-19 | 2003-06-03 | Ajinomoto Co Inc | 発酵法による目的物質の製造法 |
| ATE417094T1 (de) * | 1999-12-24 | 2008-12-15 | Ajinomoto Kk | Verfahren zur herstellung von l-aminosäure |
| RU2212447C2 (ru) * | 2000-04-26 | 2003-09-20 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" | Штамм escherichia coli - продуцент аминокислоты (варианты) и способ получения аминокислот (варианты) |
| JP4380029B2 (ja) * | 2000-07-05 | 2009-12-09 | 味の素株式会社 | 微生物を利用した物質の製造法 |
| DK1305421T3 (da) | 2000-08-04 | 2006-07-10 | Genencor Int | Foröget 2-keto-L-gulonsyre-produktion |
| CN1245215C (zh) * | 2001-02-28 | 2006-03-15 | 四川省生物工程研究中心 | 重组高效复合干扰素用作乙型肝炎表面抗原和e抗原抑制剂 |
| JP2002330763A (ja) * | 2001-05-02 | 2002-11-19 | Ajinomoto Co Inc | 発酵法による目的物質の製造法 |
| ATE441714T1 (de) | 2001-07-18 | 2009-09-15 | Evonik Degussa Gmbh | Verfahren zur herstellung von l-aminosäuren durch enterobakteriaceae-stämmen mit verstärkter exprimierung des rsea-gens |
-
2004
- 2004-06-03 US US10/859,210 patent/US7335496B2/en not_active Expired - Lifetime
- 2004-06-03 EP EP04013158A patent/EP1484410B1/en not_active Expired - Lifetime
- 2004-06-03 AT AT04013158T patent/ATE531803T1/de active
- 2004-06-04 BR BRPI0401918-0A patent/BRPI0401918B1/pt not_active IP Right Cessation
- 2004-06-04 KR KR1020040040950A patent/KR101110580B1/ko not_active Expired - Lifetime
- 2004-06-04 CN CNB2004100631895A patent/CN100564516C/zh not_active Expired - Lifetime
-
2011
- 2011-02-28 JP JP2011042797A patent/JP5287904B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ATE531803T1 (de) | 2011-11-15 |
| EP1484410A1 (en) | 2004-12-08 |
| JP5287904B2 (ja) | 2013-09-11 |
| KR101110580B1 (ko) | 2012-02-15 |
| US7335496B2 (en) | 2008-02-26 |
| CN1572868A (zh) | 2005-02-02 |
| BRPI0401918B1 (pt) | 2014-12-09 |
| KR20040105568A (ko) | 2004-12-16 |
| CN100564516C (zh) | 2009-12-02 |
| US20050170474A1 (en) | 2005-08-04 |
| EP1484410B1 (en) | 2011-11-02 |
| JP2011103899A (ja) | 2011-06-02 |
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Legal Events
| Date | Code | Title | Description |
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| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 09/12/2014, OBSERVADAS AS CONDICOES LEGAIS. |
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| B21A | Patent or certificate of addition expired [chapter 21.1 patent gazette] |
Free format text: PATENTE EXTINTA EM 09/12/2024 |