DK138501C - Analogifremgangsmaade til fremstilling af 3alfa-hydroxy-d-homo-5alfa-pregnan-11,20-dioner - Google Patents

Analogifremgangsmaade til fremstilling af 3alfa-hydroxy-d-homo-5alfa-pregnan-11,20-dioner

Info

Publication number
DK138501C
DK138501C DK588775A DK588775A DK138501C DK 138501 C DK138501 C DK 138501C DK 588775 A DK588775 A DK 588775A DK 588775 A DK588775 A DK 588775A DK 138501 C DK138501 C DK 138501C
Authority
DK
Denmark
Prior art keywords
dioner
3alfa
5alfa
pregnan
homo
Prior art date
Application number
DK588775A
Other languages
English (en)
Other versions
DK588775A (da
DK138501B (da
Inventor
U Kerb
R Wiechert
H Wachtel
O Engelfried
K Kieslich
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19742461312 external-priority patent/DE2461312A1/de
Priority claimed from DE19752506688 external-priority patent/DE2506688A1/de
Application filed by Schering Ag filed Critical Schering Ag
Publication of DK588775A publication Critical patent/DK588775A/da
Publication of DK138501B publication Critical patent/DK138501B/da
Application granted granted Critical
Publication of DK138501C publication Critical patent/DK138501C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK588775A 1974-12-23 1975-12-23 Analogifremgangsmaade til fremstilling af 3alfa-hydroxy-d-homo-5alfa-pregnan-11,20-dioner DK138501C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19742461312 DE2461312A1 (de) 1974-12-23 1974-12-23 D-homo-20-keto-pregnane und verfahren zu ihrer herstellung
DE19752506688 DE2506688A1 (de) 1975-02-14 1975-02-14 D-homo-19-nor-20-ketopregnane und verfahren zu ihrer herstellung

Publications (3)

Publication Number Publication Date
DK588775A DK588775A (da) 1976-06-24
DK138501B DK138501B (da) 1978-09-18
DK138501C true DK138501C (da) 1979-02-19

Family

ID=25768157

Family Applications (1)

Application Number Title Priority Date Filing Date
DK588775A DK138501C (da) 1974-12-23 1975-12-23 Analogifremgangsmaade til fremstilling af 3alfa-hydroxy-d-homo-5alfa-pregnan-11,20-dioner

Country Status (13)

Country Link
US (1) US4056633A (da)
JP (1) JPS5188953A (da)
AU (1) AU501685B2 (da)
CA (1) CA1051868A (da)
DD (1) DD123329A5 (da)
DK (1) DK138501C (da)
ES (1) ES443825A1 (da)
FR (1) FR2295739A1 (da)
GB (1) GB1538869A (da)
IL (1) IL48628A0 (da)
LU (1) LU74087A1 (da)
NL (1) NL7514976A (da)
SE (1) SE7514514L (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4104306A (en) * 1976-05-05 1978-08-01 Abbott Laboratories 12A-Deoxy chelocardin
US5439900A (en) * 1993-02-25 1995-08-08 Bukusoglu; Cuneyt Methods and compositions for providing analgesia and enhanced anesthesia
US20070066579A1 (en) * 2002-08-16 2007-03-22 White Michael J 5-androsten-3beta-ol steroid intermediates and processs for their preparation
JP2006507369A (ja) * 2002-08-16 2006-03-02 ファルマシア・アンド・アップジョン・カンパニー・エルエルシー ５−アンドロステン−３β−オールステロイド中間体およびそれらの製法
JP6470258B2 (ja) 2013-04-17 2019-02-13 セージ セラピューティクス， インコーポレイテッド １９−ノルｃ３，３−ジ置換ｃ２１−ｎ−ピラゾリルステロイドおよびその使用方法
ES2807264T3 (es) 2013-04-17 2021-02-22 Sage Therapeutics Inc Esteroides neuroactivos 19-nor para métodos de tratamiento
WO2014169831A1 (en) 2013-04-17 2014-10-23 Sage Therapeutics, Inc. 19-nor c3,3-disubstituted c21-c-bound heteroaryl steroids and methods of use thereof
WO2014169836A1 (en) 2013-04-17 2014-10-23 Sage Therapeutics, Inc. 19-nor neuroactive steroids and methods of use thereof
WO2015010054A2 (en) 2013-07-19 2015-01-22 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
ES2848823T3 (es) 2013-08-23 2021-08-12 Sage Therapeutics Inc Esteroides neuroactivos, composiciones y usos de los mismos
WO2015195962A1 (en) 2014-06-18 2015-12-23 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
ME03809B (me) 2014-10-16 2021-04-20 Sage Therapeutics Inc KOMPOZICIJE I POSTUPCI ZA LEČENJE POREMEĆAJA CNS-a
US10577390B2 (en) 2014-10-16 2020-03-03 Sage Therapeutics, Inc. Compositions and methods for treating CNS disorders
WO2016082789A1 (en) 2014-11-27 2016-06-02 Sage Therapeutics, Inc. Compositions and methods for treating cns disorders
WO2016123056A1 (en) 2015-01-26 2016-08-04 Sage Therapeutics, Inc. Compositions and methods for treating cns disorders
EP4155314A1 (en) 2015-02-20 2023-03-29 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
MA45599A (fr) 2016-07-11 2019-05-15 Sage Therapeutics Inc Stéroïdes neuroactifs substitués en c17, c20 et c21 et leurs procédés d'utilisation
US20190233465A1 (en) 2016-07-11 2019-08-01 Sage Therapeutics, Inc. C7, c12, and c16 substituted neuroactive steroids and their methods of use
CN111741965B (zh) * 2017-12-22 2024-06-25 萨奇治疗股份有限公司 治疗中枢神经系统疾病的组合物和方法
MA51568A (fr) * 2018-01-12 2021-04-21 Sage Therapeutics Inc Composés aza-, oxa et thia-pregnan-20-one-3.alpha.-ol s'utilisant dans le traitement de troubles du système nerveux central
IL283629B2 (en) 2018-12-05 2026-03-01 Sage Therapeutics Inc Neuroactive steroids and methods of using them
CN116589521B (zh) * 2019-01-08 2025-07-11 成都康弘药业集团股份有限公司 甾体类化合物、用途及其制备方法
CR20240234A (es) 2019-05-31 2024-07-09 Sage Therapeutics Inc ESTEROIDES NEUROACTIVOS Y COMPOSICIONES DE ESTOS (Divisional 2021-629)
US20230257415A1 (en) * 2019-06-27 2023-08-17 Sage Therapeutics, Inc. Compounds for treating cns disorders
AU2020304673A1 (en) * 2019-06-27 2022-01-20 Sage Therapeutics, Inc. Compositions and methods for treating CNS disorders
JP7787635B2 (ja) 2019-06-27 2025-12-17 セージ セラピューティクス， エルエルシー Ｃｎｓ障害を治療するための組成物及び方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3876705A (en) * 1972-06-12 1975-04-08 Univ New Brunswick Steroid total synthesis and intermediates

Also Published As

Publication number Publication date
JPS5188953A (en) 1976-08-04
AU501685B2 (en) 1979-06-28
AU8763775A (en) 1977-06-23
DD123329A5 (da) 1976-12-12
FR2295739A1 (fr) 1976-07-23
SE7514514L (sv) 1976-06-24
NL7514976A (nl) 1976-06-25
IL48628A0 (en) 1976-02-29
DK588775A (da) 1976-06-24
CA1051868A (en) 1979-04-03
ES443825A1 (es) 1977-05-01
GB1538869A (en) 1979-01-24
DK138501B (da) 1978-09-18
US4056633A (en) 1977-11-01
LU74087A1 (da) 1976-07-20

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