DK138501C - Analogifremgangsmaade til fremstilling af 3alfa-hydroxy-d-homo-5alfa-pregnan-11,20-dioner - Google Patents

Analogifremgangsmaade til fremstilling af 3alfa-hydroxy-d-homo-5alfa-pregnan-11,20-dioner

Info

Publication number
DK138501C
DK138501C DK588775A DK588775A DK138501C DK 138501 C DK138501 C DK 138501C DK 588775 A DK588775 A DK 588775A DK 588775 A DK588775 A DK 588775A DK 138501 C DK138501 C DK 138501C
Authority
DK
Denmark
Prior art keywords
dioner
3alfa
5alfa
pregnan
homo
Prior art date
Application number
DK588775A
Other languages
English (en)
Other versions
DK588775A (da
DK138501B (da
Inventor
U Kerb
R Wiechert
H Wachtel
O Engelfried
K Kieslich
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19742461312 external-priority patent/DE2461312A1/de
Priority claimed from DE19752506688 external-priority patent/DE2506688A1/de
Application filed by Schering Ag filed Critical Schering Ag
Publication of DK588775A publication Critical patent/DK588775A/da
Publication of DK138501B publication Critical patent/DK138501B/da
Application granted granted Critical
Publication of DK138501C publication Critical patent/DK138501C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK588775A 1974-12-23 1975-12-23 Analogifremgangsmaade til fremstilling af 3alfa-hydroxy-d-homo-5alfa-pregnan-11,20-dioner DK138501C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19742461312 DE2461312A1 (de) 1974-12-23 1974-12-23 D-homo-20-keto-pregnane und verfahren zu ihrer herstellung
DE19752506688 DE2506688A1 (de) 1975-02-14 1975-02-14 D-homo-19-nor-20-ketopregnane und verfahren zu ihrer herstellung

Publications (3)

Publication Number Publication Date
DK588775A DK588775A (da) 1976-06-24
DK138501B DK138501B (da) 1978-09-18
DK138501C true DK138501C (da) 1979-02-19

Family

ID=25768157

Family Applications (1)

Application Number Title Priority Date Filing Date
DK588775A DK138501C (da) 1974-12-23 1975-12-23 Analogifremgangsmaade til fremstilling af 3alfa-hydroxy-d-homo-5alfa-pregnan-11,20-dioner

Country Status (13)

Country Link
US (1) US4056633A (da)
JP (1) JPS5188953A (da)
AU (1) AU501685B2 (da)
CA (1) CA1051868A (da)
DD (1) DD123329A5 (da)
DK (1) DK138501C (da)
ES (1) ES443825A1 (da)
FR (1) FR2295739A1 (da)
GB (1) GB1538869A (da)
IL (1) IL48628A0 (da)
LU (1) LU74087A1 (da)
NL (1) NL7514976A (da)
SE (1) SE7514514L (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4104306A (en) * 1976-05-05 1978-08-01 Abbott Laboratories 12A-Deoxy chelocardin
US5439900A (en) * 1993-02-25 1995-08-08 Bukusoglu; Cuneyt Methods and compositions for providing analgesia and enhanced anesthesia
BR0313523A (pt) * 2002-08-16 2005-06-28 Upjohn Co Intermediários do esteróide 5-androsten-3(beta)-ol e processos para a sua preparação
US20070066579A1 (en) * 2002-08-16 2007-03-22 White Michael J 5-androsten-3beta-ol steroid intermediates and processs for their preparation
CN113527400B (zh) 2013-04-17 2024-06-28 萨奇治疗股份有限公司 19-去甲c3,3-二取代的c21-n-吡唑基类固醇及其使用方法
US20160068563A1 (en) 2013-04-17 2016-03-10 Boyd L. Harrison 19-nor neuroactive steroids and methods of use thereof
RU2019126333A (ru) 2013-04-17 2019-10-08 Сейдж Терапьютикс, Инк. 19-нор нейроактивные стероиды и способы их применения
WO2014169831A1 (en) 2013-04-17 2014-10-23 Sage Therapeutics, Inc. 19-nor c3,3-disubstituted c21-c-bound heteroaryl steroids and methods of use thereof
WO2015010054A2 (en) 2013-07-19 2015-01-22 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
AU2014308621C1 (en) 2013-08-23 2022-01-06 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
WO2015195962A1 (en) 2014-06-18 2015-12-23 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
MX2021004492A (es) 2014-10-16 2022-12-05 Sage Therapeutics Inc Composiciones para el tratamiento de trastornos del snc.
SMT202000414T1 (it) 2014-10-16 2020-09-10 Sage Therapeutics Inc Composizioni e metodi per trattare disturbi del snc
ME03749B (me) 2014-11-27 2021-04-20 Sage Therapeutics Inc KOMPOZICIJE I POSTUPCIZA LEČENJE POREMEĆAJA CNS-a
DK3250210T3 (da) 2015-01-26 2021-03-08 Sage Therapeutics Inc Sammensætninger og fremgangsmåder til behandling af cns-forstyrrelser
JP6875996B2 (ja) 2015-02-20 2021-05-26 セージ セラピューティクス， インコーポレイテッド 神経刺激性ステロイド、組成物、およびその使用
WO2018013613A1 (en) 2016-07-11 2018-01-18 Sage Therapeutics, Inc. C17, c20, and c21 substituted neuroactive steroids and their methods of use
CA3030420C (en) 2016-07-11 2025-11-18 Sage Therapeutics, Inc. C7, C12 AND C16 SUBSTITUTED NEUROACTIVE STEROIDS AND ASSOCIATED METHODS OF USE
US20220315621A1 (en) * 2017-12-22 2022-10-06 Sage Therapeutics, Inc. Compositions and methods for treating cns disorders
MA51568A (fr) * 2018-01-12 2021-04-21 Sage Therapeutics Inc Composés aza-, oxa et thia-pregnan-20-one-3.alpha.-ol s'utilisant dans le traitement de troubles du système nerveux central
IL312610B2 (en) 2018-12-05 2026-05-01 Sage Therapeutics Llc Neuroactive steroids and methods of using them
US12415830B2 (en) * 2019-01-08 2025-09-16 Chengdu kanghong pharmaceutical co ltd Steroid compound, and use thereof and preparation method therefor
CN114206900A (zh) 2019-05-31 2022-03-18 萨奇治疗股份有限公司 神经活性类固醇及其组合物
WO2020264495A1 (en) * 2019-06-27 2020-12-30 Sage Therapeutics, Inc. Compositions and methods for treating cns disorders
EP3990468A1 (en) * 2019-06-27 2022-05-04 Sage Therapeutics, Inc. Compounds for treating cns disorders
TWI896547B (zh) 2019-06-27 2025-09-11 美商賽吉醫療公司 用於治療cns病症之組合物及方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3876705A (en) * 1972-06-12 1975-04-08 Univ New Brunswick Steroid total synthesis and intermediates

Also Published As

Publication number Publication date
LU74087A1 (da) 1976-07-20
SE7514514L (sv) 1976-06-24
NL7514976A (nl) 1976-06-25
FR2295739A1 (fr) 1976-07-23
DK588775A (da) 1976-06-24
JPS5188953A (en) 1976-08-04
CA1051868A (en) 1979-04-03
AU501685B2 (en) 1979-06-28
DD123329A5 (da) 1976-12-12
ES443825A1 (es) 1977-05-01
US4056633A (en) 1977-11-01
DK138501B (da) 1978-09-18
AU8763775A (en) 1977-06-23
IL48628A0 (en) 1976-02-29
GB1538869A (en) 1979-01-24

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