DK588775A - D-homo-20-ketopregnaner og fremgangsmade til deres fremstilling - Google Patents
D-homo-20-ketopregnaner og fremgangsmade til deres fremstillingInfo
- Publication number
- DK588775A DK588775A DK588775A DK588775A DK588775A DK 588775 A DK588775 A DK 588775A DK 588775 A DK588775 A DK 588775A DK 588775 A DK588775 A DK 588775A DK 588775 A DK588775 A DK 588775A
- Authority
- DK
- Denmark
- Prior art keywords
- calculators
- keto
- homo
- procedures
- preparation
- Prior art date
Links
- KJDGFQJCHFJTRH-YONAWACDSA-N 16-Ketoestradiol Chemical class OC1=CC=C2[C@H]3CC[C@](C)([C@H](C(=O)C4)O)[C@@H]4[C@@H]3CCC2=C1 KJDGFQJCHFJTRH-YONAWACDSA-N 0.000 title 1
- 229930194542 Keto Natural products 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
- C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19742461312 DE2461312A1 (de) | 1974-12-23 | 1974-12-23 | D-homo-20-keto-pregnane und verfahren zu ihrer herstellung |
| DE19752506688 DE2506688A1 (de) | 1975-02-14 | 1975-02-14 | D-homo-19-nor-20-ketopregnane und verfahren zu ihrer herstellung |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK588775A true DK588775A (da) | 1976-06-24 |
| DK138501B DK138501B (da) | 1978-09-18 |
| DK138501C DK138501C (da) | 1979-02-19 |
Family
ID=25768157
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK588775A DK138501C (da) | 1974-12-23 | 1975-12-23 | Analogifremgangsmaade til fremstilling af 3alfa-hydroxy-d-homo-5alfa-pregnan-11,20-dioner |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4056633A (da) |
| JP (1) | JPS5188953A (da) |
| AU (1) | AU501685B2 (da) |
| CA (1) | CA1051868A (da) |
| DD (1) | DD123329A5 (da) |
| DK (1) | DK138501C (da) |
| ES (1) | ES443825A1 (da) |
| FR (1) | FR2295739A1 (da) |
| GB (1) | GB1538869A (da) |
| IL (1) | IL48628A0 (da) |
| LU (1) | LU74087A1 (da) |
| NL (1) | NL7514976A (da) |
| SE (1) | SE7514514L (da) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4104306A (en) * | 1976-05-05 | 1978-08-01 | Abbott Laboratories | 12A-Deoxy chelocardin |
| US5439900A (en) * | 1993-02-25 | 1995-08-08 | Bukusoglu; Cuneyt | Methods and compositions for providing analgesia and enhanced anesthesia |
| DE60308388T2 (de) * | 2002-08-16 | 2007-09-20 | Pharmacia & Upjohn Co. Llc, Kalamazoo | 5-Androsten-3beta-ol-Steroide und Verfahren für ihre Herstellung |
| US20070066579A1 (en) * | 2002-08-16 | 2007-03-22 | White Michael J | 5-androsten-3beta-ol steroid intermediates and processs for their preparation |
| SMT202100509T1 (it) | 2013-04-17 | 2021-11-12 | Sage Therapeutics Inc | Steroide di c21-n-pirazolile 19-nor c3,3-disostituito per l'uso in terapia |
| CN117304245A (zh) | 2013-04-17 | 2023-12-29 | 萨奇治疗股份有限公司 | 刺激神经活性的19-去甲类固醇及其使用方法 |
| WO2014169836A1 (en) | 2013-04-17 | 2014-10-23 | Sage Therapeutics, Inc. | 19-nor neuroactive steroids and methods of use thereof |
| US9725481B2 (en) | 2013-04-17 | 2017-08-08 | Sage Therapeutics, Inc. | 19-nor C3, 3-disubstituted C21-C-bound heteroaryl steroids and methods of use thereof |
| CA2918735C (en) | 2013-07-19 | 2023-08-01 | Sage Therapeutics, Inc. | Neuroactive steroids, compositions, and uses thereof |
| CN105579043B (zh) | 2013-08-23 | 2021-09-14 | 萨奇治疗股份有限公司 | 神经活性类固醇、组合物和其用途 |
| US10246482B2 (en) | 2014-06-18 | 2019-04-02 | Sage Therapeutics, Inc. | Neuroactive steroids, compositions, and uses thereof |
| US20170233433A1 (en) | 2014-10-16 | 2017-08-17 | Sage Therapeutics, Inc. | Compositions and methods for treating cns disorders |
| MY190408A (en) | 2014-10-16 | 2022-04-21 | Sage Therapeutics Inc | Compositions and methods for treating cns disorders |
| WO2016082789A1 (en) | 2014-11-27 | 2016-06-02 | Sage Therapeutics, Inc. | Compositions and methods for treating cns disorders |
| LT3250210T (lt) | 2015-01-26 | 2021-04-12 | Sage Therapeutics, Inc. | Kompozicijos ir būdai, skirti gydyti cns sutrikimus |
| DK3258939T3 (da) | 2015-02-20 | 2022-12-12 | Sage Therapeutics Inc | Neuroaktive steroider, sammensætninger og anvendelser heraf |
| WO2018013613A1 (en) | 2016-07-11 | 2018-01-18 | Sage Therapeutics, Inc. | C17, c20, and c21 substituted neuroactive steroids and their methods of use |
| CA3030420C (en) | 2016-07-11 | 2025-11-18 | Sage Therapeutics, Inc. | C7, C12 AND C16 SUBSTITUTED NEUROACTIVE STEROIDS AND ASSOCIATED METHODS OF USE |
| EP3728285B1 (en) * | 2017-12-22 | 2026-04-08 | Sage Therapeutics, LLC | Compositions and methods for treating cns disorders |
| JP7538040B2 (ja) * | 2018-01-12 | 2024-08-21 | セージ セラピューティクス, インコーポレイテッド | CNS障害の処置における使用のためのアザ、オキサ、およびチア-プレグナン-20-オン-3α-オール化合物 |
| IL312610B2 (en) | 2018-12-05 | 2026-05-01 | Sage Therapeutics Llc | Neuroactive steroids and methods of using them |
| CN111410678B (zh) * | 2019-01-08 | 2023-02-28 | 成都康弘药业集团股份有限公司 | 甾体类化合物、用途及其制备方法 |
| JP7670626B2 (ja) | 2019-05-31 | 2025-04-30 | セージ セラピューティクス, インコーポレイテッド | 神経刺激性ステロイド及びその組成物 |
| BR112021026447A2 (pt) * | 2019-06-27 | 2022-04-12 | Sage Therapeutics Inc | Composições e métodos para tratamento de distúrbios de cns |
| JP7787635B2 (ja) | 2019-06-27 | 2025-12-17 | セージ セラピューティクス, エルエルシー | Cns障害を治療するための組成物及び方法 |
| CA3143545A1 (en) * | 2019-06-27 | 2020-12-30 | Sage Therapeutics, Inc. | Compounds for treating cns disorders |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3876705A (en) * | 1972-06-12 | 1975-04-08 | Univ New Brunswick | Steroid total synthesis and intermediates |
-
1975
- 1975-12-09 IL IL48628A patent/IL48628A0/xx unknown
- 1975-12-17 AU AU87637/75A patent/AU501685B2/en not_active Expired
- 1975-12-17 US US05/641,602 patent/US4056633A/en not_active Expired - Lifetime
- 1975-12-19 DD DD190370A patent/DD123329A5/xx unknown
- 1975-12-22 GB GB52351/75A patent/GB1538869A/en not_active Expired
- 1975-12-22 LU LU74087A patent/LU74087A1/xx unknown
- 1975-12-22 SE SE7514514A patent/SE7514514L/xx unknown
- 1975-12-23 NL NL7514976A patent/NL7514976A/xx not_active Application Discontinuation
- 1975-12-23 DK DK588775A patent/DK138501C/da active
- 1975-12-23 ES ES443825A patent/ES443825A1/es not_active Expired
- 1975-12-23 CA CA242,439A patent/CA1051868A/en not_active Expired
- 1975-12-23 JP JP50153888A patent/JPS5188953A/ja active Pending
- 1975-12-23 FR FR7539458A patent/FR2295739A1/fr not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| IL48628A0 (en) | 1976-02-29 |
| DK138501B (da) | 1978-09-18 |
| DD123329A5 (da) | 1976-12-12 |
| DK138501C (da) | 1979-02-19 |
| ES443825A1 (es) | 1977-05-01 |
| SE7514514L (sv) | 1976-06-24 |
| NL7514976A (nl) | 1976-06-25 |
| CA1051868A (en) | 1979-04-03 |
| JPS5188953A (en) | 1976-08-04 |
| FR2295739A1 (fr) | 1976-07-23 |
| AU8763775A (en) | 1977-06-23 |
| GB1538869A (en) | 1979-01-24 |
| LU74087A1 (da) | 1976-07-20 |
| AU501685B2 (en) | 1979-06-28 |
| US4056633A (en) | 1977-11-01 |
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