DK1419167T3 - 1-(2,5'-anhydro-lyxofuranosyl) thyminer til syntese af radiomarkerede fluor-3 doxynucleotider - Google Patents
1-(2,5'-anhydro-lyxofuranosyl) thyminer til syntese af radiomarkerede fluor-3 doxynucleotiderInfo
- Publication number
- DK1419167T3 DK1419167T3 DK02796259T DK02796259T DK1419167T3 DK 1419167 T3 DK1419167 T3 DK 1419167T3 DK 02796259 T DK02796259 T DK 02796259T DK 02796259 T DK02796259 T DK 02796259T DK 1419167 T3 DK1419167 T3 DK 1419167T3
- Authority
- DK
- Denmark
- Prior art keywords
- sub
- unsubstituted
- doxynucleotides
- lyxofuranosyl
- thymines
- Prior art date
Links
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- RWQNBRDOKXIBIV-UHFFFAOYSA-N thymine Chemical class CC1=CNC(=O)NC1=O RWQNBRDOKXIBIV-UHFFFAOYSA-N 0.000 title 1
- 229910052794 bromium Inorganic materials 0.000 abstract 2
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052740 iodine Inorganic materials 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000006239 protecting group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/18—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10141300A DE10141300A1 (de) | 2001-08-23 | 2001-08-23 | Markierungsfähige Verbindungen zur einfachen Synthese von 3'-[·18·F]Fluor-3'-deoxythymidin und Verfahren zu deren Herstellung |
| PCT/EP2002/009361 WO2003018599A1 (de) | 2001-08-23 | 2002-08-21 | 1-(2,5'-anhydro-lyxofuranosyl) thymine zur synthese von radiomarkierten flour-3 deoxynucleotiden |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1419167T3 true DK1419167T3 (da) | 2005-06-13 |
Family
ID=7696335
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK02796259T DK1419167T3 (da) | 2001-08-23 | 2002-08-21 | 1-(2,5'-anhydro-lyxofuranosyl) thyminer til syntese af radiomarkerede fluor-3 doxynucleotider |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7145000B2 (da) |
| EP (1) | EP1419167B1 (da) |
| AT (1) | ATE289316T1 (da) |
| DE (2) | DE10141300A1 (da) |
| DK (1) | DK1419167T3 (da) |
| ES (1) | ES2236616T3 (da) |
| WO (1) | WO2003018599A1 (da) |
-
2001
- 2001-08-23 DE DE10141300A patent/DE10141300A1/de not_active Withdrawn
-
2002
- 2002-08-21 WO PCT/EP2002/009361 patent/WO2003018599A1/de not_active Ceased
- 2002-08-21 AT AT02796259T patent/ATE289316T1/de not_active IP Right Cessation
- 2002-08-21 DE DE50202288T patent/DE50202288D1/de not_active Expired - Fee Related
- 2002-08-21 ES ES02796259T patent/ES2236616T3/es not_active Expired - Lifetime
- 2002-08-21 DK DK02796259T patent/DK1419167T3/da active
- 2002-08-21 US US10/487,480 patent/US7145000B2/en not_active Expired - Fee Related
- 2002-08-21 EP EP02796259A patent/EP1419167B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE10141300A1 (de) | 2003-03-13 |
| ES2236616T3 (es) | 2005-07-16 |
| US7145000B2 (en) | 2006-12-05 |
| EP1419167A1 (de) | 2004-05-19 |
| US20050143338A1 (en) | 2005-06-30 |
| DE50202288D1 (de) | 2005-03-24 |
| WO2003018599A1 (de) | 2003-03-06 |
| EP1419167B1 (de) | 2005-02-16 |
| ATE289316T1 (de) | 2005-03-15 |
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