DK1421086T3 - 2-(Aminomethyl)-tetrahydro-9-oxa-1,3-diaza-cyclopenta[a]-naphthalenyl-derivater med antipsykotisk aktivitet - Google Patents

2-(Aminomethyl)-tetrahydro-9-oxa-1,3-diaza-cyclopenta[a]-naphthalenyl-derivater med antipsykotisk aktivitet

Info

Publication number: DK1421086T3
Authority: DK; Denmark
Prior art keywords: diaza; cyclopenta; oxa; aminomethyl; tetrahydro
Prior art date: 2001-07-20

Application number

DK02756528T

Other languages

English (en)

Inventor

Richard Eric Mewshaw

Rulin Zhao

Original Assignee

Wyeth Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-07-20

Filing date

2002-07-19

Publication date

2006-12-11

2002-07-19 Application filed by Wyeth Corp filed Critical Wyeth Corp

2006-12-11 Application granted granted Critical

2006-12-11 Publication of DK1421086T3 publication Critical patent/DK1421086T3/da

Links

-1 2- (Aminomethyl) -tetrahydro-9-oxa-1,3-diaza-cyclopenta [a] naphthalenyl Chemical class 0.000 title 1
230000000561 anti-psychotic effect Effects 0.000 title 1
VYFYYTLLBUKUHU-UHFFFAOYSA-N dopamine Chemical compound NCCC1=CC=C(O)C(O)=C1 VYFYYTLLBUKUHU-UHFFFAOYSA-N 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
208000035475 disorder Diseases 0.000 abstract 1
229960003638 dopamine Drugs 0.000 abstract 1
230000008482 dysregulation Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Neurology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Biomedical Technology (AREA)
Medicinal Chemistry (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Addiction (AREA)
Psychology (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

DK02756528T 2001-07-20 2002-07-19 2-(Aminomethyl)-tetrahydro-9-oxa-1,3-diaza-cyclopenta[a]-naphthalenyl-derivater med antipsykotisk aktivitet DK1421086T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US30693101P	2001-07-20	2001-07-20

Publications (1)

Publication Number	Publication Date
DK1421086T3 true DK1421086T3 (da)	2006-12-11

Family

ID=23187510

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK02756528T DK1421086T3 (da)	2001-07-20	2002-07-19	2-(Aminomethyl)-tetrahydro-9-oxa-1,3-diaza-cyclopenta[a]-naphthalenyl-derivater med antipsykotisk aktivitet

Country Status (12)

Country	Link
US (1)	US6541502B1 (da)
EP (1)	EP1421086B1 (da)
JP (1)	JP2004537556A (da)
CN (1)	CN100369916C (da)
AT (1)	ATE338046T1 (da)
BR (1)	BR0211207A (da)
CA (1)	CA2454543A1 (da)
DE (1)	DE60214397T2 (da)
DK (1)	DK1421086T3 (da)
ES (1)	ES2271314T3 (da)
MX (1)	MXPA04000581A (da)
WO (1)	WO2003008419A1 (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2008530229A (ja)	2005-02-17	2008-08-07	ワイス	シクロアルキル縮合インドール、ベンゾチオフェン、ベンゾフランおよびインデン誘導体
TW201412727A (zh) *	2012-08-24	2014-04-01	Daiichi Sankyo Co Ltd	具有鏈狀側鏈之色酮衍生物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4135474A1 (de)	1991-10-28	1993-04-29	Bayer Ag	2-aminomethyl-chromane
DE4140540A1 (de)	1991-12-09	1993-06-17	Bayer Ag	Neue azaheterocyclylmethyl-chromane
US5756532A (en)	1995-11-06	1998-05-26	American Home Products Corporation	Aminomethyl-2 3 8 9-tetrahydro-7H-1 4-dioxino 2 3-E!-indol-8-ones and derivatives
IL119483A (en)	1995-11-06	1999-06-20	American Home Prod	2-(Aminomethyl)-3,4,7,9- tetrahydro- 2H-pyrano-2[3,3-e]indol-8-ones their derivatives and pharmaceutical compositions containing them
US5750556A (en)	1996-10-30	1998-05-12	American Home Products Corporation	2-(aminomethyl)-3,4,7,9-tetrahydro-2H-pyrano- 2,3-E!indol-8-ones and derivatives
IL131158A0 (en)	1997-02-18	2001-01-28	American Home Prod	4-Aminoalkoxy-1h-benzimidazole derivatives their preparation and their use as dopamine autoreceptor (d2) agonists

2002
- 2002-07-18 US US10/197,797 patent/US6541502B1/en not_active Expired - Fee Related
- 2002-07-19 DE DE60214397T patent/DE60214397T2/de not_active Expired - Fee Related
- 2002-07-19 AT AT02756528T patent/ATE338046T1/de not_active IP Right Cessation
- 2002-07-19 MX MXPA04000581A patent/MXPA04000581A/es active IP Right Grant
- 2002-07-19 CA CA002454543A patent/CA2454543A1/en not_active Abandoned
- 2002-07-19 ES ES02756528T patent/ES2271314T3/es not_active Expired - Lifetime
- 2002-07-19 WO PCT/US2002/022981 patent/WO2003008419A1/en not_active Ceased
- 2002-07-19 DK DK02756528T patent/DK1421086T3/da active
- 2002-07-19 CN CNB028180232A patent/CN100369916C/zh not_active Expired - Fee Related
- 2002-07-19 EP EP02756528A patent/EP1421086B1/en not_active Expired - Lifetime
- 2002-07-19 JP JP2003513978A patent/JP2004537556A/ja active Pending
- 2002-07-19 BR BR0211207-8A patent/BR0211207A/pt not_active IP Right Cessation

Also Published As

Publication number	Publication date
CN1555377A (zh)	2004-12-15
ATE338046T1 (de)	2006-09-15
CN100369916C (zh)	2008-02-20
MXPA04000581A (es)	2004-04-20
BR0211207A (pt)	2004-07-13
EP1421086B1 (en)	2006-08-30
ES2271314T3 (es)	2007-04-16
DE60214397D1 (en)	2006-10-12
US6541502B1 (en)	2003-04-01
WO2003008419A1 (en)	2003-01-30
DE60214397T2 (de)	2007-10-11
EP1421086A1 (en)	2004-05-26
JP2004537556A (ja)	2004-12-16
CA2454543A1 (en)	2003-01-30

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ATE324371T1 (de)	2006-05-15	N-substituierte heterocyclische nichtaryl- nmda/nr2b-antagonisten
SE9900100D0 (sv)	1999-01-15	New compounds
PL377285A1 (pl)	2006-01-23	Podstawione pochodne pirolo-pirazolowe jako inhibitory kinazy
PT2279737E (pt)	2013-02-01	Compostos heterocíclicos, activos como inibidores de beta-lactamases
MY135841A (en)	2008-07-31	Novel benzodioxoles
NO20054852L (no)	2005-12-13	GFAT inhibitorer
EA200600203A1 (ru)	2006-08-25	Производные 2-(хиноксалин-5-илсульфониламино)бензамида в качестве модуляторов сск2
EE05362B1 (et)	2010-12-15	Aniliini derivaadid, mis on kasulikud kui fosfodiesteraas 4 inhibiitorid
TR200200579T2 (tr)	2002-12-23	Amino-tirazolpiridin türevleri.
PE20030061A1 (es)	2003-02-08	1-biaril-1,8-naftiridin-4-ona como inhibidores de fosfodiesterasa-4
BRPI0409276A (pt)	2006-04-11	derivados de piperazina inibidores de renina
NO20052908L (no)	2005-09-12	Aromatic compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents.
BRPI0417858A (pt)	2007-04-27	composto, composição farmacêutica, e, uso de uma composição farmacêutica
NO20062256L (no)	2006-06-06	Hydroksyalkylsubstituerte pyrido-7-pyrimidin-7-oner
NO20062629L (no)	2006-09-06	Oksazolderivater av tetrackliner
AU2003249535A1 (en)	2004-02-25	1,6-fused uracil derivatives as matrix metalloproteinase inhibitors
DK1558580T3 (da)	2008-01-14	N-sulfonyl-4-methylenamino-3-hydroxy-2-pyridoner
SE0200198D0 (sv)	2002-01-23	New use
ATE515266T1 (de)	2011-07-15	2-(amino-3,4-dioxo-1-cyclobuten-1- yl)aminoalkylsäure-derivate für die schmerzbehandlung
BR0211207A (pt)	2004-07-13	Derivados de 2-(aminometil)-tetrahidro-9-oxa-1,3-diaza-ciclopenta[ a]naftalenila com atividade antipsicótica
AU2002365288A1 (en)	2003-06-10	Tropane derivatives having dopamine reuptake inhibitor activity for the treatment of ischemic diseases
AU2003250465A1 (en)	2004-02-25	5,6-fused uracil derivatives as matrix metalloproteinase inhibitors
DK1409490T3 (da)	2006-10-30	2-(Aminomethyl)tetrahydro-9-oxa-1,3-diazacyclopenta[a]-naphthalenylderivater med antipsykotisk virkning
UY26568A1 (es)	2001-08-27	Nuevos derivados de amidas heterocíclicas
UY27560A1 (es)	2003-05-30	Compuestos hexaciclicos-