ATE338046T1 - 2-(aminomethyl)-tetrahydro-9-oxa-1,3-diaza- cyclopenta(a)naphthalenyl derivate mit antipsychotischer aktivität - Google Patents

2-(aminomethyl)-tetrahydro-9-oxa-1,3-diaza- cyclopenta(a)naphthalenyl derivate mit antipsychotischer aktivität

Info

Publication number: ATE338046T1
Authority: AT; Austria
Prior art keywords: diaza; cyclopenta; oxa; aminomethyl; tetrahydro
Prior art date: 2001-07-20

Application number

AT02756528T

Other languages

English (en)

Inventor

Richard Eric Mewshaw

Rulin Zhao

Original Assignee

Wyeth Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-07-20

Filing date

2002-07-19

Publication date

2006-09-15

2002-07-19 Application filed by Wyeth Corp filed Critical Wyeth Corp

2006-09-15 Application granted granted Critical

2006-09-15 Publication of ATE338046T1 publication Critical patent/ATE338046T1/de

Links

-1 2-(AMINOMETHYL)-TETRAHYDRO-9-OXA-1,3-DIAZA-CYCLOPENTA(A)NAPHTHALENYL Chemical class 0.000 title 1
230000000561 anti-psychotic effect Effects 0.000 title 1
VYFYYTLLBUKUHU-UHFFFAOYSA-N dopamine Chemical compound NCCC1=CC=C(O)C(O)=C1 VYFYYTLLBUKUHU-UHFFFAOYSA-N 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
208000035475 disorder Diseases 0.000 abstract 1
229960003638 dopamine Drugs 0.000 abstract 1
230000008482 dysregulation Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Neurology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Neurosurgery (AREA)
Medicinal Chemistry (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Addiction (AREA)
Psychology (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

AT02756528T 2001-07-20 2002-07-19 2-(aminomethyl)-tetrahydro-9-oxa-1,3-diaza- cyclopenta(a)naphthalenyl derivate mit antipsychotischer aktivität ATE338046T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US30693101P	2001-07-20	2001-07-20

Publications (1)

Publication Number	Publication Date
ATE338046T1 true ATE338046T1 (de)	2006-09-15

Family

ID=23187510

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT02756528T ATE338046T1 (de)	2001-07-20	2002-07-19	2-(aminomethyl)-tetrahydro-9-oxa-1,3-diaza- cyclopenta(a)naphthalenyl derivate mit antipsychotischer aktivität

Country Status (12)

Country	Link
US (1)	US6541502B1 (de)
EP (1)	EP1421086B1 (de)
JP (1)	JP2004537556A (de)
CN (1)	CN100369916C (de)
AT (1)	ATE338046T1 (de)
BR (1)	BR0211207A (de)
CA (1)	CA2454543A1 (de)
DE (1)	DE60214397T2 (de)
DK (1)	DK1421086T3 (de)
ES (1)	ES2271314T3 (de)
MX (1)	MXPA04000581A (de)
WO (1)	WO2003008419A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2006214233A1 (en)	2005-02-17	2006-08-24	Wyeth	Cycloalkylfused indole, benzothiophene, benzofuran and indene derivatives
WO2014030688A1 (ja) *	2012-08-24	2014-02-27	第一三共株式会社	鎖状側鎖を有するクロモン誘導体

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4135474A1 (de)	1991-10-28	1993-04-29	Bayer Ag	2-aminomethyl-chromane
DE4140540A1 (de)	1991-12-09	1993-06-17	Bayer Ag	Neue azaheterocyclylmethyl-chromane
US5756532A (en)	1995-11-06	1998-05-26	American Home Products Corporation	Aminomethyl-2 3 8 9-tetrahydro-7H-1 4-dioxino 2 3-E!-indol-8-ones and derivatives
IL119483A (en)	1995-11-06	1999-06-20	American Home Prod	2-(Aminomethyl)-3,4,7,9- tetrahydro- 2H-pyrano-2[3,3-e]indol-8-ones their derivatives and pharmaceutical compositions containing them
US5750556A (en)	1996-10-30	1998-05-12	American Home Products Corporation	2-(aminomethyl)-3,4,7,9-tetrahydro-2H-pyrano- 2,3-E!indol-8-ones and derivatives
BR9807701A (pt) *	1997-02-18	2000-05-02	American Home Prod	Derivados de 4-aminoalcóxi-1h-benzimidazol, seu preparo e seu uso como agonistas do auto-receptor (d2) de dopamina

2002
- 2002-07-18 US US10/197,797 patent/US6541502B1/en not_active Expired - Fee Related
- 2002-07-19 DK DK02756528T patent/DK1421086T3/da active
- 2002-07-19 WO PCT/US2002/022981 patent/WO2003008419A1/en not_active Ceased
- 2002-07-19 CN CNB028180232A patent/CN100369916C/zh not_active Expired - Fee Related
- 2002-07-19 AT AT02756528T patent/ATE338046T1/de not_active IP Right Cessation
- 2002-07-19 JP JP2003513978A patent/JP2004537556A/ja active Pending
- 2002-07-19 MX MXPA04000581A patent/MXPA04000581A/es active IP Right Grant
- 2002-07-19 DE DE60214397T patent/DE60214397T2/de not_active Expired - Fee Related
- 2002-07-19 EP EP02756528A patent/EP1421086B1/de not_active Expired - Lifetime
- 2002-07-19 CA CA002454543A patent/CA2454543A1/en not_active Abandoned
- 2002-07-19 BR BR0211207-8A patent/BR0211207A/pt not_active IP Right Cessation
- 2002-07-19 ES ES02756528T patent/ES2271314T3/es not_active Expired - Lifetime

Also Published As

Publication number	Publication date
MXPA04000581A (es)	2004-04-20
EP1421086A1 (de)	2004-05-26
EP1421086B1 (de)	2006-08-30
WO2003008419A1 (en)	2003-01-30
DE60214397D1 (en)	2006-10-12
DE60214397T2 (de)	2007-10-11
BR0211207A (pt)	2004-07-13
CA2454543A1 (en)	2003-01-30
ES2271314T3 (es)	2007-04-16
US6541502B1 (en)	2003-04-01
DK1421086T3 (da)	2006-12-11
CN1555377A (zh)	2004-12-15
JP2004537556A (ja)	2004-12-16
CN100369916C (zh)	2008-02-20

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Legal Events

Date	Code	Title	Description
2007-02-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties