ATE338046T1 - 2-(aminomethyl)-tetrahydro-9-oxa-1,3-diaza- cyclopenta(a)naphthalenyl derivate mit antipsychotischer aktivität - Google Patents

2-(aminomethyl)-tetrahydro-9-oxa-1,3-diaza- cyclopenta(a)naphthalenyl derivate mit antipsychotischer aktivität

Info

Publication number: ATE338046T1
Authority: AT; Austria
Prior art keywords: diaza; cyclopenta; oxa; aminomethyl; tetrahydro
Prior art date: 2001-07-20

Application number

AT02756528T

Other languages

English (en)

Inventor

Richard Eric Mewshaw

Rulin Zhao

Original Assignee

Wyeth Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-07-20

Filing date

2002-07-19

Publication date

2006-09-15

2002-07-19 Application filed by Wyeth Corp filed Critical Wyeth Corp

2006-09-15 Application granted granted Critical

2006-09-15 Publication of ATE338046T1 publication Critical patent/ATE338046T1/de

Links

-1 2-(AMINOMETHYL)-TETRAHYDRO-9-OXA-1,3-DIAZA-CYCLOPENTA(A)NAPHTHALENYL Chemical class 0.000 title 1
230000000561 anti-psychotic effect Effects 0.000 title 1
VYFYYTLLBUKUHU-UHFFFAOYSA-N dopamine Chemical compound NCCC1=CC=C(O)C(O)=C1 VYFYYTLLBUKUHU-UHFFFAOYSA-N 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
208000035475 disorder Diseases 0.000 abstract 1
229960003638 dopamine Drugs 0.000 abstract 1
230000008482 dysregulation Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Neurology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Biomedical Technology (AREA)
Medicinal Chemistry (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Addiction (AREA)
Psychology (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

AT02756528T 2001-07-20 2002-07-19 2-(aminomethyl)-tetrahydro-9-oxa-1,3-diaza- cyclopenta(a)naphthalenyl derivate mit antipsychotischer aktivität ATE338046T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US30693101P	2001-07-20	2001-07-20

Publications (1)

Publication Number	Publication Date
ATE338046T1 true ATE338046T1 (de)	2006-09-15

Family

ID=23187510

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT02756528T ATE338046T1 (de)	2001-07-20	2002-07-19	2-(aminomethyl)-tetrahydro-9-oxa-1,3-diaza- cyclopenta(a)naphthalenyl derivate mit antipsychotischer aktivität

Country Status (12)

Country	Link
US (1)	US6541502B1 (de)
EP (1)	EP1421086B1 (de)
JP (1)	JP2004537556A (de)
CN (1)	CN100369916C (de)
AT (1)	ATE338046T1 (de)
BR (1)	BR0211207A (de)
CA (1)	CA2454543A1 (de)
DE (1)	DE60214397T2 (de)
DK (1)	DK1421086T3 (de)
ES (1)	ES2271314T3 (de)
MX (1)	MXPA04000581A (de)
WO (1)	WO2003008419A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN101120002A (zh)	2005-02-17	2008-02-06	惠氏公司	环烷基稠合的吲哚、苯并噻吩、苯并呋喃和茚衍生物
TW201412727A (zh) *	2012-08-24	2014-04-01	Daiichi Sankyo Co Ltd	具有鏈狀側鏈之色酮衍生物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4135474A1 (de)	1991-10-28	1993-04-29	Bayer Ag	2-aminomethyl-chromane
DE4140540A1 (de)	1991-12-09	1993-06-17	Bayer Ag	Neue azaheterocyclylmethyl-chromane
US5756532A (en)	1995-11-06	1998-05-26	American Home Products Corporation	Aminomethyl-2 3 8 9-tetrahydro-7H-1 4-dioxino 2 3-E!-indol-8-ones and derivatives
IL119483A (en) *	1995-11-06	1999-06-20	American Home Prod	2-(Aminomethyl)-3,4,7,9- tetrahydro- 2H-pyrano-2[3,3-e]indol-8-ones their derivatives and pharmaceutical compositions containing them
US5750556A (en)	1996-10-30	1998-05-12	American Home Products Corporation	2-(aminomethyl)-3,4,7,9-tetrahydro-2H-pyrano- 2,3-E!indol-8-ones and derivatives
WO1998035945A1 (en)	1997-02-18	1998-08-20	American Home Products Corporation	4-aminoalkoxy-1h-benzimidazole derivatives, their preparation and their use as dopamine autoreceptor (d2) agonists

2002
- 2002-07-18 US US10/197,797 patent/US6541502B1/en not_active Expired - Fee Related
- 2002-07-19 CN CNB028180232A patent/CN100369916C/zh not_active Expired - Fee Related
- 2002-07-19 CA CA002454543A patent/CA2454543A1/en not_active Abandoned
- 2002-07-19 ES ES02756528T patent/ES2271314T3/es not_active Expired - Lifetime
- 2002-07-19 JP JP2003513978A patent/JP2004537556A/ja active Pending
- 2002-07-19 AT AT02756528T patent/ATE338046T1/de not_active IP Right Cessation
- 2002-07-19 DK DK02756528T patent/DK1421086T3/da active
- 2002-07-19 EP EP02756528A patent/EP1421086B1/de not_active Expired - Lifetime
- 2002-07-19 BR BR0211207-8A patent/BR0211207A/pt not_active IP Right Cessation
- 2002-07-19 WO PCT/US2002/022981 patent/WO2003008419A1/en not_active Ceased
- 2002-07-19 DE DE60214397T patent/DE60214397T2/de not_active Expired - Fee Related
- 2002-07-19 MX MXPA04000581A patent/MXPA04000581A/es active IP Right Grant

Also Published As

Publication number	Publication date
EP1421086B1 (de)	2006-08-30
JP2004537556A (ja)	2004-12-16
ES2271314T3 (es)	2007-04-16
US6541502B1 (en)	2003-04-01
DE60214397D1 (en)	2006-10-12
DE60214397T2 (de)	2007-10-11
MXPA04000581A (es)	2004-04-20
CA2454543A1 (en)	2003-01-30
EP1421086A1 (de)	2004-05-26
CN1555377A (zh)	2004-12-15
WO2003008419A1 (en)	2003-01-30
BR0211207A (pt)	2004-07-13
DK1421086T3 (da)	2006-12-11
CN100369916C (zh)	2008-02-20

Similar Documents

Publication	Publication Date	Title
DE60210944D1 (de)	2006-06-01	N-substituierte heterocyclische nichtaryl-nmda/nr2b-antagonisten
EA200600203A1 (ru)	2006-08-25	Производные 2-(хиноксалин-5-илсульфониламино)бензамида в качестве модуляторов сск2
ATE302775T1 (de)	2005-09-15	Carbolinderivate
CY1113578T1 (el)	2016-06-22	2,3-διυδρο-6-νιτροϊμιδαζο 2,1 -b-οξαζολια
ECSP045081A (es)	2004-06-28	Derivados de 1,8-naftiridina y su uso para el tratamiento de la diabetes y trastornos relacionados
DK1558579T3 (da)	2008-01-14	N-alkyl-4-methylenamino-3-hydroxy-2-pyridoner som antimikrobialer
DK1499577T3 (da)	2007-09-24	2-(2,6-dichlorphenyl)-diarylimidazoler
EA200300717A1 (ru)	2003-12-25	Гетероциклилиндазольные и -азаиндазольные соединения в качестве 5-гидрокситриптамин-6-лигандов
HRP20090281T1 (hr)	2009-06-30	1,2,3,4-tetrasubstituirani indol za liječenje respiratornih bolesti
IS7857A (is)	2005-08-18	Setnar pýrróló-pýrasól afleiður sem kínasa hindrar
EA200301142A1 (ru)	2004-02-26	Производные гетероциклилокси-, -тиокси- и -аминобензазола в качестве лигандов 5-гидрокситриптамина-6
ATE346067T1 (de)	2006-12-15	Carbolinderivate
CY1110130T1 (el)	2015-01-14	Παραγωγα μορφολινης για χρηση ως αγωνιστες ντοπαμινης στην θεραπευτικη αγωγη σεξουαλικης δυσλειτουργιας i.α.
PE20030061A1 (es)	2003-02-08	1-biaril-1,8-naftiridin-4-ona como inhibidores de fosfodiesterasa-4
EA200970372A1 (ru)	2009-10-30	Ингибитор развития болезни альцгеймера, содержащий гетероциклическое соединение
NO20052908L (no)	2005-09-12	Aromatic compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents.
BRPI0409276A (pt)	2006-04-11	derivados de piperazina inibidores de renina
BRPI0417858A (pt)	2007-04-27	composto, composição farmacêutica, e, uso de uma composição farmacêutica
HRP20080057T3 (en)	2008-02-29	9,10-alpha,alpha-oh-taxane analogs and methods for production thereof
ATE308325T1 (de)	2005-11-15	Triaryl-oxy-aryloxy-pyrimidine-2,4,6-trion derivate als metalloproteinase inhibitoren
ATE549024T1 (de)	2012-03-15	Chinazolin-kaliumkanalhemmer
DK1558580T3 (da)	2008-01-14	N-sulfonyl-4-methylenamino-3-hydroxy-2-pyridoner
SE0200198D0 (sv)	2002-01-23	New use
DK1421086T3 (da)	2006-12-11	2-(Aminomethyl)-tetrahydro-9-oxa-1,3-diaza-cyclopenta[a]-naphthalenyl-derivater med antipsykotisk aktivitet
DK1409490T3 (da)	2006-10-30	2-(Aminomethyl)tetrahydro-9-oxa-1,3-diazacyclopenta[a]-naphthalenylderivater med antipsykotisk virkning

Legal Events

Date	Code	Title	Description
2007-02-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties