DK1451143T3 - Fremgangsmåder til fremstilling af O-desmethylvenlafaxin - Google Patents

Fremgangsmåder til fremstilling af O-desmethylvenlafaxin

Info

Publication number: DK1451143T3
Authority: DK; Denmark
Prior art keywords: desmethylvenlafaxine; preparation; methods
Prior art date: 2001-12-04

Application number

DK02804479T

Other languages

Danish (da)

English (en)

Inventor

Beat Theodor Weber

Original Assignee

Wyeth Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-12-04

Filing date

2002-12-03

Publication date

2008-11-10

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23309595&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1451143(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2002-12-03 Application filed by Wyeth Corp filed Critical Wyeth Corp

2008-11-10 Application granted granted Critical

2008-11-10 Publication of DK1451143T3 publication Critical patent/DK1451143T3/da

Links

KYYIDSXMWOZKMP-UHFFFAOYSA-N O-desmethylvenlafaxine Chemical compound C1CCCCC1(O)C(CN(C)C)C1=CC=C(O)C=C1 KYYIDSXMWOZKMP-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/10—Separation; Purification; Stabilisation; Use of additives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Engineering & Computer Science (AREA)
Pain & Pain Management (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

DK02804479T 2001-12-04 2002-12-03 Fremgangsmåder til fremstilling af O-desmethylvenlafaxin DK1451143T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US33495301P	2001-12-04	2001-12-04
PCT/US2002/038403 WO2003048104A1 (en)	2001-12-04	2002-12-03	Methods for preparing o-desmethylvenlafaxine

Publications (1)

Publication Number	Publication Date
DK1451143T3 true DK1451143T3 (da)	2008-11-10

Family

ID=23309595

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK02804479T DK1451143T3 (da)	2001-12-04	2002-12-03	Fremgangsmåder til fremstilling af O-desmethylvenlafaxin

Country Status (28)

Country	Link
US (4)	US6689912B2 (de)
EP (1)	EP1451143B9 (de)
JP (1)	JP4342312B2 (de)
KR (1)	KR100939650B1 (de)
CN (1)	CN1319934C (de)
AR (1)	AR037622A1 (de)
AT (1)	ATE403641T1 (de)
AU (1)	AU2002357049B2 (de)
BR (1)	BR0214701A (de)
CA (1)	CA2466779C (de)
CO (1)	CO5580816A2 (de)
DE (1)	DE60228118D1 (de)
DK (1)	DK1451143T3 (de)
EC (1)	ECSP045135A (de)
ES (1)	ES2311647T4 (de)
HU (1)	HUP0402269A3 (de)
IL (3)	IL162253A0 (de)
MX (1)	MXPA04005309A (de)
NO (1)	NO20042680L (de)
NZ (1)	NZ533316A (de)
PL (1)	PL369299A1 (de)
PT (1)	PT1451143E (de)
RU (1)	RU2317286C2 (de)
SI (1)	SI1451143T1 (de)
TW (1)	TWI260982B (de)
UA (1)	UA80543C2 (de)
WO (1)	WO2003048104A1 (de)
ZA (1)	ZA200405250B (de)

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CA2368083A1 (en) *	1999-04-06	2000-10-12	Sepracor Inc.	Derivatives of venlafaxine and methods of preparing and using the same
EA011451B1 (ru) *	2001-02-12	2009-04-28	Уайт	Новая соль сукцинат о-десметилвенлафаксина
UA80543C2 (en) *	2001-12-04	2007-10-10	Wyeth Corp	Method for the preparation of o-desmethylvenlafaxine
EP1904046A4 (de) *	2005-07-06	2008-10-01	Sepracor Inc	Kombinationen von eszopiclon und o-desmethylvenlafaxin und verfahren zur behandlung der menopause und von stimmungsschwankungen; angstzuständen und kognitiven störungen
WO2007067501A1 (en) *	2005-12-05	2007-06-14	Wyeth	Process for selective synthesis of enantiomers of substituted 1-(2-amino-1-phenyl-ethyl)-cyclohexanols
WO2007071404A1 (en) *	2005-12-20	2007-06-28	Synthon B.V.	Process for making desvenlafaxine
EP2007708A1 (de)	2006-04-17	2008-12-31	Teva Pharmaceutical Industries Ltd	Substanziell reines o-desmethylvenlafaxin und herstellungsverfahren dafür
MX2007016179A (es) *	2006-04-17	2008-03-11	Teva Pharma	Formas cristalinas de o-desmetilvenlafaxina.
WO2008035369A2 (en) *	2006-06-30	2008-03-27	Alembic Limited	Novel form of o-desmethyl venlafaxine
US20090069601A1 (en) *	2006-07-26	2009-03-12	Valerie Niddam-Hildesheim	Processes for the synthesis of O-desmethylvenlafaxine
US20080221356A1 (en) *	2006-07-26	2008-09-11	Valerie Niddam-Hildesheim	Processes for the synthesis of O-desmethylvenlafaxine
JP4763788B2 (ja) *	2006-07-26	2011-08-31	テバファーマシューティカルインダストリーズリミティド	Ｏ−デスメチルベンラファキシンの合成方法
WO2008013994A2 (en)	2006-07-26	2008-01-31	Teva Pharmaceutical Industries Ltd.	Processes for the synthesis of o-desmethylvenlafaxine
WO2008013995A2 (en) *	2006-07-26	2008-01-31	Teva Pharmaceutical Industries Ltd.	Tridesmethylvenlafaxine and processes for the synthesis of o-desmethylvenlafaxine
US20080183016A1 (en) *	2006-07-26	2008-07-31	Valerie Niddam-Hildesheim	Process for the synthesis of O-desmethylvenlafaxine
US20090137846A1 (en) *	2006-07-26	2009-05-28	Valerie Niddam-Hildesheim	Processes for the synthesis of O-Desmethylvenlafaxine
ES2334765B1 (es) *	2006-08-04	2010-12-20	Medichem, S.A.	Proceso mejorado para sintetizar la base libre de la desvenlafaxina ysales o solvatos de la misma.
AU2008211711A1 (en) *	2007-01-31	2008-08-07	Generics [Uk] Limited	Process for the preparation of O-desmethyl venlafaxine
WO2008112313A2 (en) *	2007-03-14	2008-09-18	Teva Pharmaceutical Industries Ltd.	Processes for preparing solid states of o-desmethylvenlafaxine succinate
US20100210719A1 (en) *	2007-07-12	2010-08-19	Dr. Reddy's Laboratories Ltd.	O-desmethylvenlafaxine
IN2007CH01519A (de) *	2007-07-16	2009-09-11	Matrix Lab Ltd
WO2009034434A2 (en) *	2007-09-10	2009-03-19	Cadila Pharmaceuticals Limited	An improved process for the preparation of o-desmethylvenlafaxine
US20110118357A1 (en) *	2007-10-26	2011-05-19	Generics Limited	Process for preparing o-desmethylvenlafaxine
KR101343027B1 (ko) *	2007-11-26	2013-12-18	테바 파마슈티컬 인더스트리즈 리미티드	Ｏ-데스메틸벤라팍신 푸마레이트의 결정형
WO2009084038A2 (en) *	2007-12-28	2009-07-09	Ind-Swift Laboratories Limited	Improved process for the preparation of 0-desmethyl-venlafaxine
EP2252574A1 (de) *	2008-03-06	2010-11-24	Teva Pharmaceutical Industries Ltd.	Verfahren zur herstellung von dimer-unreinheitsfreiem o-desmethylvenlafaxin
EP2119696A1 (de)	2008-05-16	2009-11-18	Krka	Zubereitung von O-Desmethylvenlafaxin-Salzen
EP2119695A1 (de)	2008-05-16	2009-11-18	Krka	Zubereitung von O-Desmethylvenlafaxin-Salzen
US20110112200A1 (en) *	2008-06-16	2011-05-12	Valerie Niddam-Hildesheim	Solid states of o-desmethylvenlafaxine salts
US20100016638A1 (en) *	2008-07-21	2010-01-21	Zdenko Hamersak	Method for preparation of o-desmethylvenlafaxine using polythiolates
US20110263718A1 (en) *	2008-07-30	2011-10-27	Generics [Uk] Limited	Process for the preparation of o-desmethylvenlafaxine
CZ301503B6 (cs)	2008-11-27	2010-03-24	Zentiva, A. S.	Zpusob prípravy desvenlafaxinu a jeho solí
CZ301820B6 (cs)	2009-02-06	2010-06-30	Zentiva, K.S.	Nové soli desvenlafaxinu a zpusob jejich prípravy
CZ2009454A3 (cs)	2009-07-15	2010-11-10	Zentiva, K. S.	Zpusob prípravy desvenlafaxinu a jeho solí
JP2012532923A (ja)	2009-07-16	2012-12-20	シプラ・リミテッド	Ｏ−デスメチルベンラファキシンの製造方法及びそれに使用される中間体
US20110098506A1 (en) *	2009-10-26	2011-04-28	Intas Pharmaceuticals Limited	Method of preparing o-desmethylvenlafaxine
US20110184067A1 (en) *	2010-01-25	2011-07-28	Intas Pharmaceuticals Ltd.	O-desmethylvenlafaxine succinate polymorph & process for preparing thereof
CA2795023A1 (en)	2010-03-29	2011-10-06	Pliva Hrvatska D.O.O.	Crystal forms of o-desmethylvenlafaxine fumarate
CZ303249B6 (cs)	2010-04-06	2012-06-20	Zentiva, K.S.	Zpusob výroby 4-(2-(substituovaných)-1-(1-hydroxycyklohexyl)ethyl)fenolu O-demethylací jejich methyletheru pomocí nepáchnoucích aromatických thiolu
EP2394976A1 (de)	2010-06-11	2011-12-14	LEK Pharmaceuticals d.d.	Verfahren zur Demethylierung aromatischer Methylether unter Verwendung von 3-Mercaptopropionsäure
US10464873B2 (en)	2017-02-09	2019-11-05	R L Finechem Private Limited	Process for preparation of 1-[2-(dimethyl amino)-1-(4-hydroxyphenyl) ethyl]-cyclohexanol and salts thereof
CN109232189B (zh) *	2018-09-25	2021-10-08	杭州盛弗泰新材料科技有限公司	一种高纯度1-羟基芘的制备方法
CN109665966A (zh) *	2018-11-01	2019-04-23	山东蒲济医药科技有限公司	一种琥珀酸去甲文拉法辛化合物的制备方法

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DE2741009A1 (de) *	1976-09-22	1978-03-23	Sandoz Ag	4-styryl-4-indolinol-derivate, ihre verwendung und herstellung
US4535186A (en)	1983-04-19	1985-08-13	American Home Products Corporation	2-Phenyl-2-(1-hydroxycycloalkyl or 1-hydroxycycloalk-2-enyl)ethylamine derivatives
CA1227304A (en)	1984-08-01	1987-09-29	Raymond C. Francis	Delignification of pulp
GB8902209D0 (en)	1989-02-01	1989-03-22	Wyeth John And Brother Limited	Preparation of cyclohexanol derivatives and novel thioamide intermediates
US6342533B1 (en) *	1998-12-01	2002-01-29	Sepracor, Inc.	Derivatives of (−)-venlafaxine and methods of preparing and using the same
US6197828B1 (en) *	1998-12-01	2001-03-06	Sepracor, Inc.	Derivatives of (+)-venlafaxine and methods of preparing and using the same
CA2368083A1 (en)	1999-04-06	2000-10-12	Sepracor Inc.	Derivatives of venlafaxine and methods of preparing and using the same
AU5738700A (en)	1999-06-15	2001-01-02	American Home Products Corporation	Enantiomers of o-desmethyl venlafaxine
JP2004504026A (ja)	2000-07-18	2004-02-12	バイエル　アクチェンゲゼルシャフト	ヒトｄｅｓｃ１様セリンプロテアーゼの調節
EA011451B1 (ru) *	2001-02-12	2009-04-28	Уайт	Новая соль сукцинат о-десметилвенлафаксина
UA80543C2 (en) *	2001-12-04	2007-10-10	Wyeth Corp	Method for the preparation of o-desmethylvenlafaxine

2002
- 2002-03-12 UA UA20040705306A patent/UA80543C2/uk unknown
- 2002-11-26 US US10/304,871 patent/US6689912B2/en not_active Expired - Fee Related
- 2002-11-27 TW TW091134427A patent/TWI260982B/zh not_active IP Right Cessation
- 2002-12-03 DK DK02804479T patent/DK1451143T3/da active
- 2002-12-03 WO PCT/US2002/038403 patent/WO2003048104A1/en not_active Ceased
- 2002-12-03 EP EP02804479A patent/EP1451143B9/de not_active Expired - Lifetime
- 2002-12-03 JP JP2003549297A patent/JP4342312B2/ja not_active Expired - Fee Related
- 2002-12-03 CN CNB028242386A patent/CN1319934C/zh not_active Expired - Fee Related
- 2002-12-03 HU HU0402269A patent/HUP0402269A3/hu active IP Right Revival
- 2002-12-03 PT PT02804479T patent/PT1451143E/pt unknown
- 2002-12-03 DE DE60228118T patent/DE60228118D1/de not_active Expired - Lifetime
- 2002-12-03 CA CA2466779A patent/CA2466779C/en not_active Expired - Lifetime
- 2002-12-03 AT AT02804479T patent/ATE403641T1/de not_active IP Right Cessation
- 2002-12-03 NZ NZ533316A patent/NZ533316A/en unknown
- 2002-12-03 IL IL16225302A patent/IL162253A0/xx active IP Right Grant
- 2002-12-03 PL PL02369299A patent/PL369299A1/xx unknown
- 2002-12-03 AU AU2002357049A patent/AU2002357049B2/en not_active Ceased
- 2002-12-03 ES ES02804479T patent/ES2311647T4/es not_active Expired - Lifetime
- 2002-12-03 BR BR0214701-7A patent/BR0214701A/pt not_active Application Discontinuation
- 2002-12-03 AR ARP020104669A patent/AR037622A1/es unknown
- 2002-12-03 SI SI200230743T patent/SI1451143T1/sl unknown
- 2002-12-03 RU RU2004120284/04A patent/RU2317286C2/ru not_active IP Right Cessation
- 2002-12-03 KR KR1020047008512A patent/KR100939650B1/ko not_active Expired - Fee Related
- 2002-12-03 MX MXPA04005309A patent/MXPA04005309A/es active IP Right Grant
2003
- 2003-12-31 US US10/750,196 patent/US20040158101A1/en not_active Abandoned
2004
- 2004-05-31 IL IL162253A patent/IL162253A/en not_active IP Right Cessation
- 2004-06-01 CO CO04050957A patent/CO5580816A2/es active IP Right Grant
- 2004-06-04 EC EC2004005135A patent/ECSP045135A/es unknown
- 2004-06-25 NO NO20042680A patent/NO20042680L/no not_active Application Discontinuation
- 2004-07-01 ZA ZA2004/05250A patent/ZA200405250B/en unknown
2007
- 2007-06-01 US US11/756,772 patent/US7435854B2/en not_active Expired - Fee Related
2008
- 2008-09-11 US US12/208,990 patent/US20090018365A1/en not_active Abandoned
- 2008-09-11 IL IL194034A patent/IL194034A/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
KR20050044671A (ko)	2005-05-12
US20040158101A1 (en)	2004-08-12
HK1065778A1 (en)	2005-03-04
EP1451143B9 (de)	2009-08-12
PT1451143E (pt)	2008-10-21
AU2002357049A1 (en)	2003-06-17
US6689912B2 (en)	2004-02-10
JP4342312B2 (ja)	2009-10-14
CN1319934C (zh)	2007-06-06
EP1451143B1 (de)	2008-08-06
EP1451143A1 (de)	2004-09-01
SI1451143T1 (sl)	2008-12-31
MXPA04005309A (es)	2004-09-13
IL162253A0 (en)	2005-11-20
NO20042680L (no)	2004-06-25
CN1625546A (zh)	2005-06-08
PL369299A1 (en)	2005-04-18
IL162253A (en)	2009-02-11
HUP0402269A2 (hu)	2005-02-28
TWI260982B (en)	2006-09-01
KR100939650B1 (ko)	2010-02-05
UA80543C2 (en)	2007-10-10
US20070225525A1 (en)	2007-09-27
HUP0402269A3 (en)	2010-06-28
CA2466779C (en)	2013-11-19
NZ533316A (en)	2005-12-23
CO5580816A2 (es)	2005-11-30
AR037622A1 (es)	2004-11-17
JP2005511681A (ja)	2005-04-28
ES2311647T3 (es)	2009-02-16
ATE403641T1 (de)	2008-08-15
WO2003048104A1 (en)	2003-06-12
US20090018365A1 (en)	2009-01-15
CA2466779A1 (en)	2003-06-12
US7435854B2 (en)	2008-10-14
DE60228118D1 (de)	2008-09-18
US20030105358A1 (en)	2003-06-05
ZA200405250B (en)	2005-12-28
BR0214701A (pt)	2004-08-31
RU2004120284A (ru)	2005-04-10
IL194034A (en)	2010-12-30
ECSP045135A (es)	2004-07-23
RU2317286C2 (ru)	2008-02-20
AU2002357049B2 (en)	2009-07-16
ES2311647T4 (es)	2009-11-10
TW200301102A (en)	2003-07-01

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