DK1453520T3 - Sammensætning af östrogen og andre hormoner med askorbinsyre, lysin, prolin og andre stoffer - Google Patents

Sammensætning af östrogen og andre hormoner med askorbinsyre, lysin, prolin og andre stoffer

Info

Publication number: DK1453520T3
Authority: DK; Denmark
Prior art keywords: estrogen; proline; lysine; substances; hormones
Prior art date: 2001-12-14

Application number

DK01984842T

Other languages

English (en)

Inventor

Aleksandra Niedzwiecki

Vadim Ivanov

Shrirang Netke

Matthias Rath

Original Assignee

Matthias Rath

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-12-14

Filing date

2001-12-14

Publication date

2007-01-15

2001-12-14 Application filed by Matthias Rath filed Critical Matthias Rath

2007-01-15 Application granted granted Critical

2007-01-15 Publication of DK1453520T3 publication Critical patent/DK1453520T3/da

Links

CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 title abstract 4
ONIBWKKTOPOVIA-BYPYZUCNSA-N L-Proline Chemical compound OC(=O)[C@@H]1CCCN1 ONIBWKKTOPOVIA-BYPYZUCNSA-N 0.000 title abstract 2
KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 title abstract 2
KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 title abstract 2
239000004472 Lysine Substances 0.000 title abstract 2
ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 title abstract 2
235000010323 ascorbic acid Nutrition 0.000 title abstract 2
239000011668 ascorbic acid Substances 0.000 title abstract 2
229940011871 estrogen Drugs 0.000 title abstract 2
239000000262 estrogen Substances 0.000 title abstract 2
229940088597 hormone Drugs 0.000 title abstract 2
239000005556 hormone Substances 0.000 title abstract 2
239000000203 mixture Substances 0.000 title abstract 2
239000000126 substance Substances 0.000 title abstract 2
229960005070 ascorbic acid Drugs 0.000 title 1
239000003814 drug Substances 0.000 abstract 2
229940072107 ascorbate Drugs 0.000 abstract 1
210000002808 connective tissue Anatomy 0.000 abstract 1
239000002537 cosmetic Substances 0.000 abstract 1
230000003054 hormonal effect Effects 0.000 abstract 1
230000009245 menopause Effects 0.000 abstract 1
230000035479 physiological effects, processes and functions Effects 0.000 abstract 1
238000009256 replacement therapy Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/401—Proline; Derivatives thereof, e.g. captopril
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/26—Iron; Compounds thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/34—Copper; Compounds thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Endocrinology (AREA)
Physical Education & Sports Medicine (AREA)
Diabetes (AREA)
Inorganic Chemistry (AREA)
Molecular Biology (AREA)
Rheumatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Dermatology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Reproductive Health (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Steroid Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Plant Substances (AREA)

DK01984842T 2001-12-14 2001-12-14 Sammensætning af östrogen og andre hormoner med askorbinsyre, lysin, prolin og andre stoffer DK1453520T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
PCT/EP2001/014726 WO2003051371A1 (en)	2001-12-14	2001-12-14	Composition of estrogen and other hormones with ascorbate, lysine, proline and other substances

Publications (1)

Publication Number	Publication Date
DK1453520T3 true DK1453520T3 (da)	2007-01-15

Family

ID=8164723

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK01984842T DK1453520T3 (da)	2001-12-14	2001-12-14	Sammensætning af östrogen og andre hormoner med askorbinsyre, lysin, prolin og andre stoffer

Country Status (22)

Country	Link
EP (1)	EP1453520B1 (da)
JP (1)	JP2005511768A (da)
KR (1)	KR20040063950A (da)
CN (1)	CN1582152A (da)
AT (1)	ATE338555T1 (da)
AU (1)	AU2002233257B2 (da)
BR (1)	BR0116856A (da)
CA (1)	CA2467964C (da)
CZ (1)	CZ2004809A3 (da)
DE (1)	DE60122943T2 (da)
DK (1)	DK1453520T3 (da)
EE (1)	EE200300310A (da)
ES (1)	ES2272555T3 (da)
HR (1)	HRP20040611B1 (da)
HU (1)	HUP0500896A3 (da)
IL (1)	IL162013A0 (da)
MX (1)	MXPA04005771A (da)
NO (1)	NO20033555L (da)
NZ (1)	NZ532976A (da)
PT (1)	PT1453520E (da)
SI (1)	SI21785A (da)
WO (1)	WO2003051371A1 (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20040253319A1 (en) *	2003-06-11	2004-12-16	Shrirang Netke	Pharmaceutical compositions and method for alleviating side-effects of estrogen replacement therapy
KR100903984B1 (ko) *	2005-02-01	2009-06-25	주식회사 이매진	Aimp1 폴리펩티드 또는 이의 단편을 유효성분으로 포함하는 피부 노화 방지, 주름 개선, 피부 유연 증진 및 탄력 증진용 화장료 조성물
WO2008139314A1 (en) *	2007-05-11	2008-11-20	Horphag Research (Luxembourg) Holding Sa	Compositions and methods for treating joint disorders
WO2010146078A2 (en) *	2009-06-16	2010-12-23	Bergen Teknologioverføring As	Novel uses of hydroxyproline compositions
JP6125899B2 (ja) *	2012-05-25	2017-05-10	ライオン株式会社	骨粗鬆症予防および／または改善剤
WO2013176054A1 (ja) *	2012-05-25	2013-11-28	ライオン株式会社	アスコルビン酸誘導体を含む剤およびその用途
JP6018800B2 (ja) *	2012-05-25	2016-11-02	ライオン株式会社	経口投与組成物
CN113244227B (zh) *	2020-02-12	2022-09-02	浙江医药股份有限公司新昌制药厂	一种17β-雌二醇与维生素C的分子复合物及其制备方法及应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB888631A (en) *	1959-02-24	1962-01-31	Upjohn Co	Improvements in or relating to oral therapeutic compositions comprising steroids
US4980358A (en) *	1988-04-04	1990-12-25	George D. McAdory	Method employing gonadal hormones and dopamine agonist intended for combined use in the improvement of lymphocyte function
CA2078804C (en) *	1991-10-01	2003-02-25	Takehiko Suzuki	Manufacture and use of novel glycosides of catechol estrogens
EP1068868A3 (en) *	1997-07-08	2001-01-31	Rath, Matthias, Dr. med.	Synergistic compositions comprising ascorbate and lysine for states related to extracellular matrix degeneration
DE29916231U1 (de) *	1999-09-15	2000-02-17	Renner, Jobst, Dr., 81479 München	Multivitamin- und -mineralpräparat

2001
- 2001-12-14 DK DK01984842T patent/DK1453520T3/da active
- 2001-12-14 CN CNA018238793A patent/CN1582152A/zh active Pending
- 2001-12-14 KR KR10-2004-7009041A patent/KR20040063950A/ko not_active Ceased
- 2001-12-14 SI SI200120070A patent/SI21785A/sl not_active IP Right Cessation
- 2001-12-14 CZ CZ2004809A patent/CZ2004809A3/cs unknown
- 2001-12-14 DE DE60122943T patent/DE60122943T2/de not_active Expired - Fee Related
- 2001-12-14 MX MXPA04005771A patent/MXPA04005771A/es active IP Right Grant
- 2001-12-14 IL IL16201301A patent/IL162013A0/xx unknown
- 2001-12-14 HU HU0500896A patent/HUP0500896A3/hu unknown
- 2001-12-14 AU AU2002233257A patent/AU2002233257B2/en not_active Ceased
- 2001-12-14 JP JP2003552304A patent/JP2005511768A/ja active Pending
- 2001-12-14 BR BR0116856-8A patent/BR0116856A/pt not_active IP Right Cessation
- 2001-12-14 WO PCT/EP2001/014726 patent/WO2003051371A1/en not_active Ceased
- 2001-12-14 EP EP01984842A patent/EP1453520B1/en not_active Expired - Lifetime
- 2001-12-14 ES ES01984842T patent/ES2272555T3/es not_active Expired - Lifetime
- 2001-12-14 CA CA002467964A patent/CA2467964C/en not_active Expired - Fee Related
- 2001-12-14 NZ NZ532976A patent/NZ532976A/en unknown
- 2001-12-14 HR HR20040611A patent/HRP20040611B1/xx not_active IP Right Cessation
- 2001-12-14 EE EEP200300310A patent/EE200300310A/xx unknown
- 2001-12-14 AT AT01984842T patent/ATE338555T1/de not_active IP Right Cessation
- 2001-12-14 PT PT01984842T patent/PT1453520E/pt unknown
2003
- 2003-08-11 NO NO20033555A patent/NO20033555L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
CA2467964A1 (en)	2003-06-26
SI21785A (sl)	2005-12-31
DE60122943D1 (de)	2006-10-19
IL162013A0 (en)	2005-11-20
CZ2004809A3 (cs)	2004-12-15
CA2467964C (en)	2008-06-03
NZ532976A (en)	2006-02-24
ES2272555T3 (es)	2007-05-01
BR0116856A (pt)	2004-08-03
WO2003051371A1 (en)	2003-06-26
EP1453520A1 (en)	2004-09-08
CN1582152A (zh)	2005-02-16
HUP0500896A2 (en)	2007-02-28
HRP20040611A2 (en)	2005-04-30
EE200300310A (et)	2003-10-15
DE60122943T2 (de)	2007-04-26
ATE338555T1 (de)	2006-09-15
MXPA04005771A (es)	2004-09-10
PT1453520E (pt)	2006-12-29
EP1453520B1 (en)	2006-09-06
NO20033555D0 (no)	2003-08-11
KR20040063950A (ko)	2004-07-14
HUP0500896A3 (en)	2008-04-28
NO20033555L (no)	2003-10-02
HRP20040611B1 (hr)	2008-03-31
AU2002233257B2 (en)	2008-08-14
AU2002233257A1 (en)	2003-06-30
JP2005511768A (ja)	2005-04-28

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BG108225A (en)	2005-04-30	Thiohydantoins and use thereof for treating diabetes
ATE383849T1 (de)	2008-02-15	Transdermale pharmazeutische zusammensetzung
MY144992A (en)	2011-12-15	Substituted 1,2,3,4-tetrahydroisoquinoline derivatives.
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ATE269846T1 (de)	2004-07-15	N-substituierte aminotetraline als neuropeptid y y5 rezeptor-liganden und ihre anwendung zur behandlung von fettleibigkeit und anderen erkrankungen
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SG146648A1 (en)	2008-10-30	Pharmaceutical compositions for treating premature ejaculation by pulmonary inhalation
EA200201000A1 (ru)	2003-02-27	Гормон-заместительная терапия
DE60331236D1 (de)	2010-03-25	Orale zusammensetzungen zur behandlung von diabetes
BRPI0113286B8 (pt)	2021-05-25	pirazóis substituídos e composição farmacêutica compreendendo os mesmos.
BRPI0416700A (pt)	2007-03-06	métodos para tratar obesidade, para alcançar perda de peso desejável, para evitar ganho de peso indesejável, e para facilitar a perda de peso em um indivìduo não sofrendo de depressão, métodos de manutenção de um peso estável e de redução do peso corporal em um indivìduo, composição farmacêutica, e, kit
ATE312090T1 (de)	2005-12-15	4-(piperidyl- und pyrrolidyl-alkyl-ureido)- chinoline als urotensin ii rezeptor antagonisten
AR057060A1 (es)	2007-11-14	Composiciones de tanaproget que contienen etinil estradiol
EA200301022A1 (ru)	2004-02-26	Гормональная заместительная терапия
BR9702200A (pt)	1999-07-20	Compostos bicíclicos-aromáticos composição farmacéutica composição cosmética e utilização de uma composição cosmética
DE60233433D1 (de)	2009-10-01	PHARMAZEUTISCHE ZUBEREITUNG enthaltend ein Catechin, Ascorbinsäure, Prolin und Lysin ZUR BEHANDLUNG VON NEOPLASTISCHEN KRANKHEITEN
MY144897A (en)	2011-11-30	2,3,4,9-tetrahydro-1h-carbazole derivatives as crth2 receptor antagonists
DE60324431D1 (de)	2008-12-11	Derivate des 3-hydroxy-4-(cyclyl-alkylaminoalkyl)-5-phenyl-1h-pyrazols als antagonisten des gonadotropin freisetzenden hormons (gnrh) zur anwendung in de behandlung von geschlechtshormonellen erkrankungen, wie prostata- oder gebahrmutterkrebs
AU1727797A (en)	1997-08-28	Heterocyclic biaryl compounds, pharmaceutical and cosmetic compositions containing them and uses thereof
NO20033555L (no)	2003-10-02	Sammensetning av östrogen og andre hormoner med askorbatlysin, prolin og andre stoffer
BR9708297A (pt)	1999-08-03	Compostos composição farmacéutica cosmposição e uso de uma composição cosmética
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BRPI0407039A (pt)	2006-01-17	Uso de uma combinação de um inibidor de aromatase, uma progestina e um estrogênio, composição farmacêutica, e, método do tratamento de endometriose
MX2007003119A (es)	2007-05-24	Nuevas amidas heterociclicas.
EP1474396A4 (en)	2006-01-18	N-SUBSTITUTE3-HYDROXY-4-PYRIDINONES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME