DK1465535T3 - Mikrofremspring til gennemstikning af huden med stikdybdestyring - Google Patents

Mikrofremspring til gennemstikning af huden med stikdybdestyring

Info

Publication number
DK1465535T3
DK1465535T3 DK02805673T DK02805673T DK1465535T3 DK 1465535 T3 DK1465535 T3 DK 1465535T3 DK 02805673 T DK02805673 T DK 02805673T DK 02805673 T DK02805673 T DK 02805673T DK 1465535 T3 DK1465535 T3 DK 1465535T3
Authority
DK
Denmark
Prior art keywords
piercing
skin
depth control
micro projections
plug depth
Prior art date
Application number
DK02805673T
Other languages
Danish (da)
English (en)
Inventor
Joseph C Trautman
Michel J N Cormier
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Application granted granted Critical
Publication of DK1465535T3 publication Critical patent/DK1465535T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/20—Surgical instruments, devices or methods for vaccinating or cleaning the skin previous to the vaccination
    • A61B17/205—Vaccinating by means of needles or other puncturing devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
    • A61B5/1451—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid
    • A61B5/14514—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid using means for aiding extraction of interstitial fluid, e.g. microneedles or suction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A61N1/303—Constructional details
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/03—Automatic limiting or abutting means, e.g. for safety
    • A61B2090/033—Abutting means, stops, e.g. abutting on tissue or skin
    • A61B2090/034—Abutting means, stops, e.g. abutting on tissue or skin abutting on parts of the device itself
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0038—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a channel at the side surface
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046—Solid microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Medical Informatics (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Optics & Photonics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Surgical Instruments (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
DK02805673T 2001-12-20 2002-12-20 Mikrofremspring til gennemstikning af huden med stikdybdestyring DK1465535T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34255301P 2001-12-20 2001-12-20
PCT/US2002/041208 WO2003053258A1 (fr) 2001-12-20 2002-12-20 Microprojections pour le percage de la peau a regulation de la profondeur de percage

Publications (1)

Publication Number Publication Date
DK1465535T3 true DK1465535T3 (da) 2008-04-07

Family

ID=23342327

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02805673T DK1465535T3 (da) 2001-12-20 2002-12-20 Mikrofremspring til gennemstikning af huden med stikdybdestyring

Country Status (12)

Country Link
US (1) US20030181936A1 (fr)
EP (1) EP1465535B1 (fr)
AU (1) AU2002357372B2 (fr)
DE (1) DE60223844T2 (fr)
DK (1) DK1465535T3 (fr)
ES (1) ES2297056T3 (fr)
HU (1) HUP0402605A2 (fr)
NO (1) NO20043044L (fr)
PT (1) PT1465535E (fr)
RU (1) RU2314760C2 (fr)
WO (1) WO2003053258A1 (fr)
ZA (1) ZA200405732B (fr)

Families Citing this family (77)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0914178B1 (fr) * 1996-06-18 2003-03-12 Alza Corporation Dispositif d'amelioration d'apport ou d'echantillonnage d'agents transdermiques
US6918901B1 (en) * 1997-12-10 2005-07-19 Felix Theeuwes Device and method for enhancing transdermal agent flux
PL360998A1 (en) * 2000-10-13 2004-09-20 Alza Corporation Apparatus and method for piercing skin with microprotrusions
US7419481B2 (en) * 2000-10-13 2008-09-02 Alza Corporation Apparatus and method for piercing skin with microprotrusions
CA2425312C (fr) * 2000-10-13 2010-02-16 Alza Corporation Logement pour element a microprotrusions pour applicateur a percussion
BR0114909A (pt) * 2000-10-26 2004-02-03 Alza Corp Dispositivos de distribuição de drogas transdérmicas possuindo microprotuberâncias revestidas
US6855372B2 (en) * 2001-03-16 2005-02-15 Alza Corporation Method and apparatus for coating skin piercing microprojections
US20020193729A1 (en) * 2001-04-20 2002-12-19 Cormier Michel J.N. Microprojection array immunization patch and method
US6908453B2 (en) * 2002-01-15 2005-06-21 3M Innovative Properties Company Microneedle devices and methods of manufacture
KR20120087197A (ko) 2002-07-19 2012-08-06 쓰리엠 이노베이티브 프로퍼티즈 컴파니 마이크로 니들 장치, 마이크로 니들 장치를 사용하는 방법 및 마이크로 니들 장치를 송출하는 방법
US20040115167A1 (en) * 2002-09-30 2004-06-17 Michel Cormier Drug delivery device and method having coated microprojections incorporating vasoconstrictors
AR042815A1 (es) * 2002-12-26 2005-07-06 Alza Corp Dispositivo de suministro de agente activo que tiene miembros compuestos
US20050123507A1 (en) * 2003-06-30 2005-06-09 Mahmoud Ameri Formulations for coated microprojections having controlled solubility
MXPA06000281A (es) * 2003-06-30 2006-07-03 Johnson & Johnson Formulaciones para microproyecciones revestidas que contienen contraiones no volatiles.
EP1643918A1 (fr) * 2003-07-02 2006-04-12 Alza Corporation Timbre transdermique et methode d'immunisation mettant en oeuvre un reseau de microprojections
BRPI0413360A (pt) * 2003-08-04 2006-10-10 Alza Corp método e dispositivo para aumentar o fluxo de agentes transdérmicos
BRPI0415850A (pt) * 2003-10-23 2007-01-02 Alza Corp composição de dna estabilizado para o revestimento de micro projeções
EP1675539A4 (fr) * 2003-10-24 2007-09-12 Alza Corp Procede et systeme de pretraitement permettant d'ameliorer l'administration transdermique de medicaments
US7455654B2 (en) * 2003-10-28 2008-11-25 Alza Corporation Method and apparatus for reducing the incidence of tobacco use
CA2543641A1 (fr) 2003-10-31 2005-05-19 Alza Corporation Applicateur a actionnement automatique pour reseau de micro-protuberances
US8535299B2 (en) * 2004-01-23 2013-09-17 Joseph Giovannoli Method and apparatus for skin reduction
GB0402131D0 (en) 2004-01-30 2004-03-03 Isis Innovation Delivery method
EP1718452A1 (fr) * 2004-02-23 2006-11-08 3M Innovative Properties Company Procede de moulage de reseau de micro-aiguilles
CA2562642A1 (fr) * 2004-04-13 2005-11-03 Alza Corporation Appareil et procede d'administration transdermique de multiples vaccins
MXPA06013168A (es) * 2004-05-13 2007-05-15 Johnson & Johnson Aparato y metodo para el suministro transdermico de agentes de la hormona paratiroidea.
US20060030811A1 (en) * 2004-08-03 2006-02-09 Wong Patrick S Method and device for enhancing transdermal agent flux
KR20070099540A (ko) * 2004-09-08 2007-10-09 알자 코포레이션 향상된 피부 점착성 및 순응도를 갖는 미세돌출부 어레이
TW200700094A (en) * 2005-01-31 2007-01-01 Alza Corp Coated microprojections having reduced variability and method for producing same
EP1898807A1 (fr) * 2005-03-28 2008-03-19 Alza Corporation Microprojections dotees d'elements de commande capillaire et procede correspondant
US20070078414A1 (en) 2005-08-05 2007-04-05 Mcallister Devin V Methods and devices for delivering agents across biological barriers
CA2619452A1 (fr) * 2005-09-12 2007-03-22 Alza Corporation Dispositif d'administration transdermique enduisable a microprojections
US10299871B2 (en) 2005-09-30 2019-05-28 Restoration Robotics, Inc. Automated system and method for hair removal
US7962192B2 (en) * 2005-09-30 2011-06-14 Restoration Robotics, Inc. Systems and methods for aligning a tool with a desired location or object
US7658728B2 (en) * 2006-01-10 2010-02-09 Yuzhakov Vadim V Microneedle array, patch, and applicator for transdermal drug delivery
AU2007225056A1 (en) * 2006-03-15 2007-09-20 Alza Corporation Apparatus and method for transdermal delivery of parathyroid hormone agents to prevent or treat osteopenia
US20070224252A1 (en) * 2006-03-27 2007-09-27 Trautman Joseph C Microprojections with capillary control features and method
US20070293816A1 (en) * 2006-04-25 2007-12-20 Alza Corporation Microprojection Array Application with Grouped Microprojections for High Drug Loading
US20070299388A1 (en) * 2006-04-25 2007-12-27 Alza Corporation Microprojection array application with multilayered microprojection member for high drug loading
US9220678B2 (en) 2007-12-24 2015-12-29 The University Of Queensland Coating method
EP2247527A4 (fr) 2008-02-07 2014-10-29 Univ Queensland Fabrication de timbre transdermique
WO2009146072A1 (fr) 2008-04-01 2009-12-03 The General Hospital Corporation Procédé et appareil de dilatation de tissu
AU2009250341A1 (en) 2008-05-23 2009-11-26 The University Of Queensland Analyte detection using a needle projection patch
US20100331867A1 (en) * 2009-06-26 2010-12-30 Joseph Giovannoli Apparatus and method for dermal incision
EP2566568B1 (fr) * 2010-05-04 2019-04-10 Corium International, Inc. Applicateurs pour micro-aiguilles
WO2012006677A1 (fr) 2010-07-14 2012-01-19 The University Of Queensland Appareil d'application de timbre transdermique
US9498289B2 (en) 2010-12-21 2016-11-22 Restoration Robotics, Inc. Methods and systems for directing movement of a tool in hair transplantation procedures
KR20120119250A (ko) * 2011-04-21 2012-10-31 (주)마이티시스템 단턱이 형성된 미세바늘
WO2013053022A1 (fr) 2011-10-12 2013-04-18 The University Of Queensland Dispositif de distribution
WO2013187392A1 (fr) * 2012-06-12 2013-12-19 久光製薬株式会社 Feuille de micro-aiguilles
EP2958533B8 (fr) 2013-02-20 2022-02-16 Cytrellis Biosystems, Inc. Procédés et dispositifs pour le resserrement de la peau
EP3030175B1 (fr) 2013-08-09 2023-10-04 Cytrellis Biosystems, Inc. Appareils pour le traitement de la peau à l'aide d'une ablation de tissu non thermique
US20160206866A1 (en) * 2013-09-06 2016-07-21 Hisamitsu Pharmaceutical Co., Inc. Micro-Needle Sheet
US10953143B2 (en) 2013-12-19 2021-03-23 Cytrellis Biosystems, Inc. Methods and devices for manipulating subdermal fat
EP2905047A1 (fr) * 2014-02-10 2015-08-12 LTS LOHMANN Therapie-Systeme AG Système de micro-aiguille et son procédé de fabrication
FI3834824T3 (fi) 2014-03-28 2025-12-05 Univ Duke Estrogeenireseptoripositiivisen rintasyövän hoito selektiivisellä estrogeenireseptorin modulaattorilla
KR102670286B1 (ko) 2014-11-14 2024-05-30 사이트렐리스 바이오시스템즈, 인크. 피부 절제를 위한 디바이스 및 방법
AU2016214968B2 (en) 2015-02-02 2021-02-25 Vaxxas Pty Limited Microprojection array applicator and method
WO2016149152A1 (fr) 2015-03-13 2016-09-22 The University Of North Carolina At Chapel Hill Micro-aiguilles polymères et fabrication additive rapide de ces dernières
US9743949B2 (en) 2015-04-22 2017-08-29 Medline Industries, Inc. Two-dimensional needle array device and method of use
JP7019422B2 (ja) 2015-04-29 2022-02-15 ラジウス ファーマシューティカルズ，インコーポレイテッド 癌を治療するための方法
WO2017045031A1 (fr) 2015-09-18 2017-03-23 Vaxxas Pty Limited Réseaux de micro-saillies comportant des micro-saillies ayant des profils à surface élevée
EP3355981B1 (fr) 2015-09-28 2025-11-19 Vaxxas Pty Limited Réseau de microsaillies ayant des propriétés de pénétration de la peau améliorées et procédés associés
GB201517373D0 (en) 2015-10-01 2015-11-18 Ge Healthcare Uk Ltd Micro-Needle Sampling Device And Use Thereof
EP3363491B1 (fr) * 2015-10-15 2019-12-11 Toppan Printing Co., Ltd. Instrument d'administration
AU2017245174A1 (en) 2016-03-29 2018-10-04 Cytrellis Biosystems, Inc. Devices and methods for cosmetic skin resurfacing
CN109922740B (zh) 2016-09-21 2022-08-23 希特利斯生物系统有限公司 用于美容皮肤重建的装置和方法
KR102707399B1 (ko) 2017-01-05 2024-09-13 래디어스 파마슈티컬스, 인코포레이티드 Rad1901-2hcl의 다형 형태
EP3606760B1 (fr) 2017-03-31 2023-09-27 Vaxxas Pty Limited Dispositif et procédé de revêtement de surfaces
US11175128B2 (en) 2017-06-13 2021-11-16 Vaxxas Pty Limited Quality control of substrate coatings
US11464957B2 (en) 2017-08-04 2022-10-11 Vaxxas Pty Limited Compact high mechanical energy storage and low trigger force actuator for the delivery of microprojection array patches (MAP)
JP6920179B2 (ja) * 2017-11-15 2021-08-18 新光電気工業株式会社 生体用電極部品及びその製造方法
IL279853B2 (en) 2018-07-04 2025-01-01 Radius Pharmaceuticals Inc Polymorphic forms of RAD 1901-2HCL
AU2019352635B2 (en) 2018-10-02 2024-12-19 WearOptimo Pty Ltd Actuator system
US20210338158A1 (en) * 2018-10-02 2021-11-04 WearOptimo Pty Ltd Measurement system
WO2020069568A1 (fr) 2018-10-02 2020-04-09 WearOptimo Pty Ltd Système d'administration d'un traitement
CN113348163B (zh) 2019-02-12 2024-10-08 雷迪厄斯制药公司 方法和化合物
WO2025073879A1 (fr) * 2023-10-05 2025-04-10 Danmarks Tekniske Universitet Structures multifonctionnelles 3d à échelle micrométrique basées sur le principe du kirigami

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3123212A (en) * 1964-03-03 Multiple disposable intracutaneous injector package
US2619962A (en) * 1948-02-19 1952-12-02 Res Foundation Vaccination appliance
US2893392A (en) * 1958-01-08 1959-07-07 American Cyanamid Co Article of manufacture for intracutaneous injections
US3072122A (en) * 1959-01-15 1963-01-08 Rosenthal Sol Roy Package for transcutaneous injection
US3034507A (en) * 1960-05-10 1962-05-15 American Cyanamid Co Intracutaneous injection device
US3221739A (en) * 1962-03-26 1965-12-07 Rosenthal Sol Roy Injection device
US3221740A (en) * 1962-08-31 1965-12-07 Rosenthal Sol Roy Injection device
US3678150A (en) * 1971-07-27 1972-07-18 American Cyanamid Co Process for improving the stability of ppd, qt and histoplasmin on tine applicators
SE8501990D0 (sv) * 1985-04-24 1985-04-24 Pharmacia Ab Beleggningsforfarande
US5810857A (en) 1993-08-12 1998-09-22 Mackool; Richard J. Surgical knife for controlled lengthening of an incision
US5643308A (en) * 1995-02-28 1997-07-01 Markman; Barry Stephen Method and apparatus for forming multiple cavities for placement of hair grafts
WO1996037155A1 (fr) 1995-05-22 1996-11-28 Silicon Microdevices, Inc. Dispositif micromecanique et procede pour ameliorer l'administration percutanee de composes
EP0914178B1 (fr) * 1996-06-18 2003-03-12 Alza Corporation Dispositif d'amelioration d'apport ou d'echantillonnage d'agents transdermiques
US5820562A (en) * 1997-11-05 1998-10-13 Hsiao; Ray-Ling Skin allergy test device having step-shaped punctures
US6918901B1 (en) * 1997-12-10 2005-07-19 Felix Theeuwes Device and method for enhancing transdermal agent flux
CA2313698C (fr) * 1997-12-11 2008-04-15 Alza Corporation Dispositif renforcant le flux d'agents transdermiques
DE69839969D1 (de) * 1997-12-11 2008-10-16 Alza Corp Vorrichtung zur verbesserung des transdermalen flusses von medikamenten
JP4061022B2 (ja) * 1997-12-11 2008-03-12 アルザ・コーポレーション 経皮輸送剤の流量促進装置
JP3109470B2 (ja) * 1998-03-11 2000-11-13 日本電気株式会社 角質層穿刺針及び角質層穿刺部材
US6091975A (en) * 1998-04-01 2000-07-18 Alza Corporation Minimally invasive detecting device
GB2354446A (en) * 1999-09-21 2001-03-28 John Arthur Lunn Multiple puncture device
US6623457B1 (en) * 1999-09-22 2003-09-23 Becton, Dickinson And Company Method and apparatus for the transdermal administration of a substance
US6197039B1 (en) 1999-12-09 2001-03-06 Bahman Ashraf Triple pointed micro knife
HK1048604B (en) 1999-12-10 2006-05-04 Alza Corporation Device and method for enhancing microprotrusion skin piercing
US6558361B1 (en) * 2000-03-09 2003-05-06 Nanopass Ltd. Systems and methods for the transport of fluids through a biological barrier and production techniques for such systems
US6645226B1 (en) * 2000-05-19 2003-11-11 Coapt Systems, Inc. Multi-point tension distribution system device and method of tissue approximation using that device to improve wound healing
US6589202B1 (en) * 2000-06-29 2003-07-08 Becton Dickinson And Company Method and apparatus for transdermally sampling or administering a substance to a patient
PL360998A1 (en) 2000-10-13 2004-09-20 Alza Corporation Apparatus and method for piercing skin with microprotrusions
PL360978A1 (en) * 2000-10-13 2004-09-20 Alza Corporation Microblade array impact applicator
CA2425312C (fr) * 2000-10-13 2010-02-16 Alza Corporation Logement pour element a microprotrusions pour applicateur a percussion
BR0114909A (pt) * 2000-10-26 2004-02-03 Alza Corp Dispositivos de distribuição de drogas transdérmicas possuindo microprotuberâncias revestidas
US6855372B2 (en) * 2001-03-16 2005-02-15 Alza Corporation Method and apparatus for coating skin piercing microprojections
NZ529029A (en) * 2001-04-20 2005-07-29 Alza Corp Microprojection array having a beneficial agent containing coating

Also Published As

Publication number Publication date
HUP0402605A2 (hu) 2005-06-28
ZA200405732B (en) 2005-08-11
ES2297056T3 (es) 2008-05-01
EP1465535A1 (fr) 2004-10-13
WO2003053258A1 (fr) 2003-07-03
US20030181936A1 (en) 2003-09-25
DE60223844D1 (de) 2008-01-10
PT1465535E (pt) 2008-02-08
DE60223844T2 (de) 2008-08-28
NO20043044L (no) 2004-09-17
RU2314760C2 (ru) 2008-01-20
RU2004122100A (ru) 2005-03-20
AU2002357372A1 (en) 2003-07-09
AU2002357372B2 (en) 2008-11-20
EP1465535B1 (fr) 2007-11-28

Similar Documents

Publication Publication Date Title
DK1465535T3 (da) Mikrofremspring til gennemstikning af huden med stikdybdestyring
DK1638468T3 (da) Fremgangsmåde til coating af hudpiercingmikrofremspring
DE602004004227D1 (de) Lanzette mit Auslösevorrichtung zur Steuerung der Eindringtiefe
PL339530A1 (en) Puncturing depth adjusting assembly for puncturing devices
DK1383560T4 (da) Infusionssæt
DE60238879D1 (de) Polymere elektrochrome Vorrichtung
DE60103669T2 (de) Einstichnadel
BR0106287B1 (pt) seringa de segurança.
DE60142664D1 (de) Fuzzy-logic Steuerung
DE50114713D1 (de) Mikrostrukturbauelement
DE10055987B8 (de) Elektronisch gesteuerter oder geregelter Thermostat
DE60113760D1 (de) Synchronregelungsvorrichtung
AU2003301204A8 (en) Precision controlled thermostat
DE60222937D1 (de) Schubsteuervorrichtung
ATA13512001A (de) Stecker
DE50110880D1 (de) Gleitelementvorrichtung
ATE459085T1 (de) Temperaturbegrenzer
DE60221939D1 (de) Kupplungssteuerungsverfahren
DE50111203D1 (de) Synchronisiereinrichtung mit asymmetrischer verzahnung
EP1544161A4 (fr) Element structurel tridimensionnel et procede de fabrication de l'element, commutateur optique et microdispositif
GB0319822D0 (en) Temperature controlled membrane interface device
DE60135131D1 (de) Stecker
ES1055827Y (es) Puntal con dispositivo de seguridad.
FI20002308A7 (fi) Saunan kiuas
FI20035068A0 (fi) Läpivientikappale