DK147086A - Farmaceutisk komposition til kombinationsterapi af hormonafhaengige cancertyper - Google Patents

Farmaceutisk komposition til kombinationsterapi af hormonafhaengige cancertyper Download PDF

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Publication number
DK147086A
DK147086A DK147086A DK147086A DK147086A DK 147086 A DK147086 A DK 147086A DK 147086 A DK147086 A DK 147086A DK 147086 A DK147086 A DK 147086A DK 147086 A DK147086 A DK 147086A
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DK
Denmark
Prior art keywords
cancer types
antiandrogen
biosynthesis
inhibitor
pharmaceutical composition
Prior art date
Application number
DK147086A
Other languages
English (en)
Other versions
DK168516B1 (da
DK147086D0 (da
Inventor
Fernand Labrie
Alain Belanger
Andre Dupont
Original Assignee
Fernand Labrie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/636,883 external-priority patent/US4775660A/en
Priority claimed from US06/699,702 external-priority patent/US4666885A/en
Priority claimed from US06/699,711 external-priority patent/US4659695A/en
Priority claimed from US06/699,710 external-priority patent/US5023234A/en
Application filed by Fernand Labrie filed Critical Fernand Labrie
Publication of DK147086D0 publication Critical patent/DK147086D0/da
Publication of DK147086A publication Critical patent/DK147086A/da
Application granted granted Critical
Publication of DK168516B1 publication Critical patent/DK168516B1/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
DK147086A 1984-08-02 1986-04-01 Sæt til kombinationsterapi af visse kønshormonafhængige cancertyper hos et varmblodet dyr DK168516B1 (da)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US63688384 1984-08-02
US06/636,883 US4775660A (en) 1984-08-02 1984-08-02 Treatment of breast cancer by combination therapy
US69971085 1985-02-08
US69970285 1985-02-08
US69971185 1985-02-08
US06/699,702 US4666885A (en) 1985-02-08 1985-02-08 Combination therapy for treatment of female breast cancer
US06/699,711 US4659695A (en) 1985-02-08 1985-02-08 Method of treatment of prostate cancer
US06/699,710 US5023234A (en) 1985-02-08 1985-02-08 Combination male breast cancer therapy
PCT/US1985/001454 WO1986001105A1 (en) 1984-08-02 1985-08-02 Pharmaceutical composition for combination therapy of hormone dependent cancers
US8501454 1985-08-02

Publications (3)

Publication Number Publication Date
DK147086D0 DK147086D0 (da) 1986-04-01
DK147086A true DK147086A (da) 1986-04-01
DK168516B1 DK168516B1 (da) 1994-04-11

Family

ID=27505215

Family Applications (1)

Application Number Title Priority Date Filing Date
DK147086A DK168516B1 (da) 1984-08-02 1986-04-01 Sæt til kombinationsterapi af visse kønshormonafhængige cancertyper hos et varmblodet dyr

Country Status (8)

Country Link
EP (1) EP0195015B1 (da)
JP (1) JPH0680016B2 (da)
AT (1) ATE75947T1 (da)
AU (1) AU594309B2 (da)
DE (2) DE3586053D1 (da)
DK (1) DK168516B1 (da)
IE (1) IE58836B1 (da)
WO (1) WO1986001105A1 (da)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2012488A (en) * 1987-07-31 1989-02-02 Syntex (U.S.A.) Inc. Combination therapy with lhrh antagonist analogs and 19nor progestational steroids
DE3733478A1 (de) * 1987-10-01 1989-04-13 Schering Ag Antigestagen- und antioestrogenwirksame verbindungen zur geburtseinleitung und zum schwangerschaftsabbruch sowie zur behandlung gynaekologischer stoerungen und hormonabhaengiger tumore
HU199694B (en) * 1988-05-10 1990-03-28 Innofinance Altalanos Innovaci Process for producing citostatic pharmaceutical compositions containing gonadoliberin derivatives
US5686465A (en) * 1988-10-31 1997-11-11 Endorecherche Inc. Sex steroid activity inhibitors
US5395842A (en) * 1988-10-31 1995-03-07 Endorecherche Inc. Anti-estrogenic compounds and compositions
US5204337A (en) * 1988-10-31 1993-04-20 Endorecherche Inc. Estrogen nucleus derivatives for use in inhibition of sex steroid activity
US5364847A (en) * 1989-03-10 1994-11-15 Endorecherche Inhibitors of sex steroid biosynthesis and methods for their production and use
US5372996A (en) * 1989-03-10 1994-12-13 Endorecherche, Inc. Method of treatment of androgen-related diseases
US5595985A (en) 1989-03-10 1997-01-21 Endorecherche Inc. Combination therapy for prophylaxis and/or treatment of benign prostatic hyperplasia
PH30747A (en) * 1989-03-10 1997-10-17 Endorech Inc Combination therapy for the treatment of estrogen sensitive disease.
DE3921059A1 (de) * 1989-06-23 1991-01-10 Schering Ag 11(beta)-aryl-4-estrene, verfahren zu ihrer herstellung sowie deren verwendung als arzneimittel
WO1991000731A1 (en) * 1989-07-07 1991-01-24 Endorecherche Inc. Combination therapy for prophylaxis and/or treatment of benign prostatic hyperplasia
CA2062792C (en) * 1989-07-07 2006-03-21 Fernard Labrie Treatment of androgen-related diseases
US4990538A (en) * 1989-08-23 1991-02-05 Harris Adrian L Use of toremifene and its metabolites for the reversal of multidrug resistance of cancer cells against cytotoxic drugs
ZA924811B (en) * 1991-06-28 1993-12-29 Endorecherche Inc Controlled release systems and low dose androgens
HU222501B1 (hu) * 1991-06-28 2003-07-28 Endorecherche Inc. MPA-t vagy MGA-t tartalmazó nyújtott hatóanyag-felszabadulású gyógyászati készítmény és eljárás előállítására
US6060503A (en) * 1991-12-02 2000-05-09 Endorecherche, Inc. Benzopyran-containing compounds and method for their use
HUT71514A (en) * 1992-05-21 1995-12-28 Endorecherche Inc Inhibitors of testosterone 5 alfa-reductase activity and pharmaceutical compositions containing the same
ZA961564B (en) * 1995-02-28 1997-08-27 Lilly Co Eli Methods of inhibiting ovarian cancer.
EP0729754A2 (en) * 1995-02-28 1996-09-04 Eli Lilly And Company 2-Phenyl-3-aroylbonzothiophenes for inhibiting estrogen positive tumors of the brain or CNS
FR2736550B1 (fr) * 1995-07-14 1998-07-24 Sandoz Sa Composition pharmaceutique sous la forme d'une dispersion solide comprenant un macrolide et un vehicule
JP2002506077A (ja) 1998-03-11 2002-02-26 アンドルシェルシュ・インコーポレイテッド タイプ５およびタイプ３１７β−ヒドロキシステロイドデヒドロゲナーゼのインヒビターおよびその使用法
US6465445B1 (en) * 1998-06-11 2002-10-15 Endorecherche, Inc. Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors
US7005428B1 (en) 1998-06-11 2006-02-28 Endorecherche, Inc. Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors
EP1424080B1 (en) * 2001-08-10 2011-02-16 Takeda Pharmaceutical Company Limited Gnrh agonist combination drugs
RU2315763C2 (ru) 2001-09-06 2008-01-27 Шеринг Корпорейшн Соединение и фармацевтическая композиция
CN1571782A (zh) 2001-10-17 2005-01-26 先灵公司 作为3型17β－羟基类固醇脱氢酶抑制剂用于治疗雄激素依赖疾病的哌啶乙酰胺类化合物和哌嗪乙酰胺类化合物
PE20040750A1 (es) 2002-11-18 2004-11-06 Schering Corp Derivados de n-(1-acetilpiperidin-4-il)-4-benzidril-2-isopropilpiperazin-1-carboxamida como inhibidores de 17beta-hidroxiesteroide deshidrogenasa de tipo 3
CA2509758A1 (en) 2002-12-17 2004-07-22 Schering Corporation 17 beta-hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases
GB0513702D0 (en) 2005-07-04 2005-08-10 Sterix Ltd Compound
GB0722779D0 (en) 2007-11-20 2008-01-02 Sterix Ltd Compound
CN115862804B (zh) * 2022-11-25 2023-12-19 成都诺医德医学检验实验室有限公司 双药联用的联合用药的推荐方法及装置

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4329364A (en) * 1974-09-11 1982-05-11 Schering Corporation Antiandrogenic agents and methods for the treatment of androgen dependent disease states
FR2329276A1 (fr) * 1975-10-29 1977-05-27 Roussel Uclaf Nouvelles imidazolidines substituees, procede de preparation, application comme medicament et compositions les renfermant
DE2921593C2 (de) * 1979-05-28 1984-02-02 Gränges Nyby AB, Nybybruk Verfahren und Vorrichtung zum Weiterzerkleinern von hydriertem, grobstückigem Material, insbes. Schrott aus Titan oder dessen Legierungen
ZA822247B (en) * 1981-04-03 1983-11-30 Lilly Co Eli Benzothiophene compounds and process for preparing them

Also Published As

Publication number Publication date
DE3590389T1 (de) 1986-08-28
DK168516B1 (da) 1994-04-11
DE3586053D1 (de) 1992-06-17
EP0195015B1 (en) 1992-05-13
AU4728285A (en) 1986-03-07
DK147086D0 (da) 1986-04-01
IE58836B1 (en) 1993-11-17
ATE75947T1 (de) 1992-05-15
IE851929L (en) 1986-02-02
JPH0680016B2 (ja) 1994-10-12
JPS62500451A (ja) 1987-02-26
EP0195015A1 (en) 1986-09-24
WO1986001105A1 (en) 1986-02-27
AU594309B2 (en) 1990-03-08

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PBP Patent lapsed
B1 Patent granted (law 1993)
PUP Patent expired