DK147086D0 - Farmaceutisk komposition til kombinationsterapi af hormonafhaengige cancertyper - Google Patents
Farmaceutisk komposition til kombinationsterapi af hormonafhaengige cancertyperInfo
- Publication number
- DK147086D0 DK147086D0 DK147086A DK147086A DK147086D0 DK 147086 D0 DK147086 D0 DK 147086D0 DK 147086 A DK147086 A DK 147086A DK 147086 A DK147086 A DK 147086A DK 147086 D0 DK147086 D0 DK 147086D0
- Authority
- DK
- Denmark
- Prior art keywords
- cancer types
- sex steroid
- antiandrogen
- inhibitor
- combination therapy
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 3
- 238000002648 combination therapy Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 201000011510 cancer Diseases 0.000 title 2
- 239000003163 gonadal steroid hormone Substances 0.000 abstract 4
- 230000002280 anti-androgenic effect Effects 0.000 abstract 3
- 239000000051 antiandrogen Substances 0.000 abstract 3
- 230000015572 biosynthetic process Effects 0.000 abstract 3
- 239000003112 inhibitor Substances 0.000 abstract 3
- 229940046836 anti-estrogen Drugs 0.000 abstract 2
- 230000001833 anti-estrogenic effect Effects 0.000 abstract 2
- 239000000328 estrogen antagonist Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 206010006187 Breast cancer Diseases 0.000 abstract 1
- 208000026310 Breast neoplasm Diseases 0.000 abstract 1
- 206010060862 Prostate cancer Diseases 0.000 abstract 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000001419 dependent effect Effects 0.000 abstract 1
- 239000005556 hormone Substances 0.000 abstract 1
- 229940088597 hormone Drugs 0.000 abstract 1
- 210000001672 ovary Anatomy 0.000 abstract 1
- 238000012360 testing method Methods 0.000 abstract 1
- 210000001550 testis Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63688384 | 1984-08-02 | ||
| US06/636,883 US4775660A (en) | 1984-08-02 | 1984-08-02 | Treatment of breast cancer by combination therapy |
| US06/699,702 US4666885A (en) | 1985-02-08 | 1985-02-08 | Combination therapy for treatment of female breast cancer |
| US06/699,710 US5023234A (en) | 1985-02-08 | 1985-02-08 | Combination male breast cancer therapy |
| US69971185 | 1985-02-08 | ||
| US69970285 | 1985-02-08 | ||
| US69971085 | 1985-02-08 | ||
| US06/699,711 US4659695A (en) | 1985-02-08 | 1985-02-08 | Method of treatment of prostate cancer |
| PCT/US1985/001454 WO1986001105A1 (en) | 1984-08-02 | 1985-08-02 | Pharmaceutical composition for combination therapy of hormone dependent cancers |
| US8501454 | 1985-08-02 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK147086A DK147086A (da) | 1986-04-01 |
| DK147086D0 true DK147086D0 (da) | 1986-04-01 |
| DK168516B1 DK168516B1 (da) | 1994-04-11 |
Family
ID=27505215
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK147086A DK168516B1 (da) | 1984-08-02 | 1986-04-01 | Sæt til kombinationsterapi af visse kønshormonafhængige cancertyper hos et varmblodet dyr |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0195015B1 (da) |
| JP (1) | JPH0680016B2 (da) |
| AT (1) | ATE75947T1 (da) |
| AU (1) | AU594309B2 (da) |
| DE (2) | DE3586053D1 (da) |
| DK (1) | DK168516B1 (da) |
| IE (1) | IE58836B1 (da) |
| WO (1) | WO1986001105A1 (da) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2012488A (en) * | 1987-07-31 | 1989-02-02 | Syntex (U.S.A.) Inc. | Combination therapy with lhrh antagonist analogs and 19nor progestational steroids |
| DE3733478A1 (de) * | 1987-10-01 | 1989-04-13 | Schering Ag | Antigestagen- und antioestrogenwirksame verbindungen zur geburtseinleitung und zum schwangerschaftsabbruch sowie zur behandlung gynaekologischer stoerungen und hormonabhaengiger tumore |
| HU199694B (en) * | 1988-05-10 | 1990-03-28 | Innofinance Altalanos Innovaci | Process for producing citostatic pharmaceutical compositions containing gonadoliberin derivatives |
| US5204337A (en) * | 1988-10-31 | 1993-04-20 | Endorecherche Inc. | Estrogen nucleus derivatives for use in inhibition of sex steroid activity |
| US5395842A (en) * | 1988-10-31 | 1995-03-07 | Endorecherche Inc. | Anti-estrogenic compounds and compositions |
| US5686465A (en) * | 1988-10-31 | 1997-11-11 | Endorecherche Inc. | Sex steroid activity inhibitors |
| US5364847A (en) * | 1989-03-10 | 1994-11-15 | Endorecherche | Inhibitors of sex steroid biosynthesis and methods for their production and use |
| ES2077675T3 (es) * | 1989-03-10 | 1995-12-01 | Endorecherche Inc | Terapia combinada para el tratamiento de enfermedades sensibles a los estrogenos. |
| US5595985A (en) | 1989-03-10 | 1997-01-21 | Endorecherche Inc. | Combination therapy for prophylaxis and/or treatment of benign prostatic hyperplasia |
| US5372996A (en) * | 1989-03-10 | 1994-12-13 | Endorecherche, Inc. | Method of treatment of androgen-related diseases |
| DE3921059A1 (de) * | 1989-06-23 | 1991-01-10 | Schering Ag | 11(beta)-aryl-4-estrene, verfahren zu ihrer herstellung sowie deren verwendung als arzneimittel |
| ATE269066T1 (de) * | 1989-07-07 | 2004-07-15 | Endorech Inc | Kombinationstherapie zur prophylaxe und/oder behandlung von gutartiger prostatischer hyperplasie |
| HUT60139A (en) * | 1989-07-07 | 1992-08-28 | Endorecherche Inc | Process for producing pharmaceutical composition suitable for treating prostate cancer connected with androgen |
| US4990538A (en) * | 1989-08-23 | 1991-02-05 | Harris Adrian L | Use of toremifene and its metabolites for the reversal of multidrug resistance of cancer cells against cytotoxic drugs |
| HU222501B1 (hu) * | 1991-06-28 | 2003-07-28 | Endorecherche Inc. | MPA-t vagy MGA-t tartalmazó nyújtott hatóanyag-felszabadulású gyógyászati készítmény és eljárás előállítására |
| ZA924811B (en) * | 1991-06-28 | 1993-12-29 | Endorecherche Inc | Controlled release systems and low dose androgens |
| US6060503A (en) * | 1991-12-02 | 2000-05-09 | Endorecherche, Inc. | Benzopyran-containing compounds and method for their use |
| JPH07506575A (ja) * | 1992-05-21 | 1995-07-20 | アンドルシェルシュ・インコーポレイテッド | テストステロン5α−レダクターゼ活性の阻害剤 |
| ZA961564B (en) * | 1995-02-28 | 1997-08-27 | Lilly Co Eli | Methods of inhibiting ovarian cancer. |
| EP0729754A2 (en) * | 1995-02-28 | 1996-09-04 | Eli Lilly And Company | 2-Phenyl-3-aroylbonzothiophenes for inhibiting estrogen positive tumors of the brain or CNS |
| BE1009856A5 (fr) * | 1995-07-14 | 1997-10-07 | Sandoz Sa | Composition pharmaceutique sous la forme d'une dispersion solide comprenant un macrolide et un vehicule. |
| TR200002784T2 (tr) | 1998-03-11 | 2000-12-21 | Endorecherche, Inc | Tip 5 ve tip 3 17beta-Hidroksisteroid dehidrojenaz inhibitörleri ve bunların kullanımı için metodlar |
| US6465445B1 (en) | 1998-06-11 | 2002-10-15 | Endorecherche, Inc. | Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors |
| US7005428B1 (en) | 1998-06-11 | 2006-02-28 | Endorecherche, Inc. | Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors |
| DE60239207D1 (de) * | 2001-08-10 | 2011-03-31 | Takeda Pharmaceutical | Gnrh-agonistische kombinationsmittel |
| AR036492A1 (es) | 2001-09-06 | 2004-09-15 | Schering Corp | Inhibidores de la 17beta-hidroxiesteroide deshidrogenasa tipo 3, composiciones farmaceuticas y el uso de dichos inhibidores para la elaboracion de un medicamento para el tratamiento de enfermedades androgeno dependientes |
| MXPA04003611A (es) | 2001-10-17 | 2004-07-30 | Schering Corp | Piperidina- y piperazinacetaminas como inhibidores de la 17 beta-hidroxiesteroide deshidrogenasa tipo 3 para el tratamiento de enfermedades androgeno-dependientes. |
| WO2004046111A1 (en) | 2002-11-18 | 2004-06-03 | Schering Corporation | 17beta-hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases |
| MXPA05006485A (es) | 2002-12-17 | 2005-08-26 | Schering Corp | Inhibidores de la 17 beta-hidroxiesteroide deshidrogenasa tipo 3 para el tratamiento de enfermedades dependientes de androgeno. |
| GB0513702D0 (en) | 2005-07-04 | 2005-08-10 | Sterix Ltd | Compound |
| GB0722779D0 (en) | 2007-11-20 | 2008-01-02 | Sterix Ltd | Compound |
| CN115862804B (zh) * | 2022-11-25 | 2023-12-19 | 成都诺医德医学检验实验室有限公司 | 双药联用的联合用药的推荐方法及装置 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4329364A (en) * | 1974-09-11 | 1982-05-11 | Schering Corporation | Antiandrogenic agents and methods for the treatment of androgen dependent disease states |
| FR2329276A1 (fr) * | 1975-10-29 | 1977-05-27 | Roussel Uclaf | Nouvelles imidazolidines substituees, procede de preparation, application comme medicament et compositions les renfermant |
| DE2921593C2 (de) * | 1979-05-28 | 1984-02-02 | Gränges Nyby AB, Nybybruk | Verfahren und Vorrichtung zum Weiterzerkleinern von hydriertem, grobstückigem Material, insbes. Schrott aus Titan oder dessen Legierungen |
| ZA822247B (en) * | 1981-04-03 | 1983-11-30 | Lilly Co Eli | Benzothiophene compounds and process for preparing them |
-
1985
- 1985-08-02 DE DE8585904034T patent/DE3586053D1/de not_active Expired - Lifetime
- 1985-08-02 WO PCT/US1985/001454 patent/WO1986001105A1/en not_active Ceased
- 1985-08-02 DE DE19853590389 patent/DE3590389T1/de not_active Withdrawn
- 1985-08-02 JP JP60503509A patent/JPH0680016B2/ja not_active Expired - Lifetime
- 1985-08-02 AU AU47282/85A patent/AU594309B2/en not_active Expired
- 1985-08-02 AT AT85904034T patent/ATE75947T1/de not_active IP Right Cessation
- 1985-08-02 IE IE192985A patent/IE58836B1/en not_active IP Right Cessation
- 1985-08-02 EP EP85904034A patent/EP0195015B1/en not_active Expired - Lifetime
-
1986
- 1986-04-01 DK DK147086A patent/DK168516B1/da not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0195015B1 (en) | 1992-05-13 |
| IE851929L (en) | 1986-02-02 |
| DK168516B1 (da) | 1994-04-11 |
| AU4728285A (en) | 1986-03-07 |
| AU594309B2 (en) | 1990-03-08 |
| DK147086A (da) | 1986-04-01 |
| DE3590389T1 (de) | 1986-08-28 |
| WO1986001105A1 (en) | 1986-02-27 |
| EP0195015A1 (en) | 1986-09-24 |
| ATE75947T1 (de) | 1992-05-15 |
| IE58836B1 (en) | 1993-11-17 |
| JPS62500451A (ja) | 1987-02-26 |
| DE3586053D1 (de) | 1992-06-17 |
| JPH0680016B2 (ja) | 1994-10-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed | ||
| B1 | Patent granted (law 1993) | ||
| PUP | Patent expired |