DK147086D0 - Farmaceutisk komposition til kombinationsterapi af hormonafhaengige cancertyper - Google Patents

Farmaceutisk komposition til kombinationsterapi af hormonafhaengige cancertyper

Info

Publication number
DK147086D0
DK147086D0 DK147086A DK147086A DK147086D0 DK 147086 D0 DK147086 D0 DK 147086D0 DK 147086 A DK147086 A DK 147086A DK 147086 A DK147086 A DK 147086A DK 147086 D0 DK147086 D0 DK 147086D0
Authority
DK
Denmark
Prior art keywords
cancer types
sex steroid
antiandrogen
inhibitor
combination therapy
Prior art date
Application number
DK147086A
Other languages
English (en)
Other versions
DK168516B1 (da
DK147086A (da
Inventor
Fernand Labrie
Alain Belanger
Andre Dupont
Original Assignee
Fernand Labrie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/636,883 external-priority patent/US4775660A/en
Priority claimed from US06/699,702 external-priority patent/US4666885A/en
Priority claimed from US06/699,710 external-priority patent/US5023234A/en
Priority claimed from US06/699,711 external-priority patent/US4659695A/en
Application filed by Fernand Labrie filed Critical Fernand Labrie
Publication of DK147086A publication Critical patent/DK147086A/da
Publication of DK147086D0 publication Critical patent/DK147086D0/da
Application granted granted Critical
Publication of DK168516B1 publication Critical patent/DK168516B1/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
DK147086A 1984-08-02 1986-04-01 Sæt til kombinationsterapi af visse kønshormonafhængige cancertyper hos et varmblodet dyr DK168516B1 (da)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US63688384 1984-08-02
US06/636,883 US4775660A (en) 1984-08-02 1984-08-02 Treatment of breast cancer by combination therapy
US06/699,702 US4666885A (en) 1985-02-08 1985-02-08 Combination therapy for treatment of female breast cancer
US06/699,710 US5023234A (en) 1985-02-08 1985-02-08 Combination male breast cancer therapy
US69971185 1985-02-08
US69970285 1985-02-08
US69971085 1985-02-08
US06/699,711 US4659695A (en) 1985-02-08 1985-02-08 Method of treatment of prostate cancer
PCT/US1985/001454 WO1986001105A1 (en) 1984-08-02 1985-08-02 Pharmaceutical composition for combination therapy of hormone dependent cancers
US8501454 1985-08-02

Publications (3)

Publication Number Publication Date
DK147086A DK147086A (da) 1986-04-01
DK147086D0 true DK147086D0 (da) 1986-04-01
DK168516B1 DK168516B1 (da) 1994-04-11

Family

ID=27505215

Family Applications (1)

Application Number Title Priority Date Filing Date
DK147086A DK168516B1 (da) 1984-08-02 1986-04-01 Sæt til kombinationsterapi af visse kønshormonafhængige cancertyper hos et varmblodet dyr

Country Status (8)

Country Link
EP (1) EP0195015B1 (da)
JP (1) JPH0680016B2 (da)
AT (1) ATE75947T1 (da)
AU (1) AU594309B2 (da)
DE (2) DE3586053D1 (da)
DK (1) DK168516B1 (da)
IE (1) IE58836B1 (da)
WO (1) WO1986001105A1 (da)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2012488A (en) * 1987-07-31 1989-02-02 Syntex (U.S.A.) Inc. Combination therapy with lhrh antagonist analogs and 19nor progestational steroids
DE3733478A1 (de) * 1987-10-01 1989-04-13 Schering Ag Antigestagen- und antioestrogenwirksame verbindungen zur geburtseinleitung und zum schwangerschaftsabbruch sowie zur behandlung gynaekologischer stoerungen und hormonabhaengiger tumore
HU199694B (en) * 1988-05-10 1990-03-28 Innofinance Altalanos Innovaci Process for producing citostatic pharmaceutical compositions containing gonadoliberin derivatives
US5204337A (en) * 1988-10-31 1993-04-20 Endorecherche Inc. Estrogen nucleus derivatives for use in inhibition of sex steroid activity
US5395842A (en) * 1988-10-31 1995-03-07 Endorecherche Inc. Anti-estrogenic compounds and compositions
US5686465A (en) * 1988-10-31 1997-11-11 Endorecherche Inc. Sex steroid activity inhibitors
US5364847A (en) * 1989-03-10 1994-11-15 Endorecherche Inhibitors of sex steroid biosynthesis and methods for their production and use
ES2077675T3 (es) * 1989-03-10 1995-12-01 Endorecherche Inc Terapia combinada para el tratamiento de enfermedades sensibles a los estrogenos.
US5595985A (en) 1989-03-10 1997-01-21 Endorecherche Inc. Combination therapy for prophylaxis and/or treatment of benign prostatic hyperplasia
US5372996A (en) * 1989-03-10 1994-12-13 Endorecherche, Inc. Method of treatment of androgen-related diseases
DE3921059A1 (de) * 1989-06-23 1991-01-10 Schering Ag 11(beta)-aryl-4-estrene, verfahren zu ihrer herstellung sowie deren verwendung als arzneimittel
ATE269066T1 (de) * 1989-07-07 2004-07-15 Endorech Inc Kombinationstherapie zur prophylaxe und/oder behandlung von gutartiger prostatischer hyperplasie
HUT60139A (en) * 1989-07-07 1992-08-28 Endorecherche Inc Process for producing pharmaceutical composition suitable for treating prostate cancer connected with androgen
US4990538A (en) * 1989-08-23 1991-02-05 Harris Adrian L Use of toremifene and its metabolites for the reversal of multidrug resistance of cancer cells against cytotoxic drugs
HU222501B1 (hu) * 1991-06-28 2003-07-28 Endorecherche Inc. MPA-t vagy MGA-t tartalmazó nyújtott hatóanyag-felszabadulású gyógyászati készítmény és eljárás előállítására
ZA924811B (en) * 1991-06-28 1993-12-29 Endorecherche Inc Controlled release systems and low dose androgens
US6060503A (en) * 1991-12-02 2000-05-09 Endorecherche, Inc. Benzopyran-containing compounds and method for their use
JPH07506575A (ja) * 1992-05-21 1995-07-20 アンドルシェルシュ・インコーポレイテッド テストステロン5α−レダクターゼ活性の阻害剤
ZA961564B (en) * 1995-02-28 1997-08-27 Lilly Co Eli Methods of inhibiting ovarian cancer.
EP0729754A2 (en) * 1995-02-28 1996-09-04 Eli Lilly And Company 2-Phenyl-3-aroylbonzothiophenes for inhibiting estrogen positive tumors of the brain or CNS
BE1009856A5 (fr) * 1995-07-14 1997-10-07 Sandoz Sa Composition pharmaceutique sous la forme d'une dispersion solide comprenant un macrolide et un vehicule.
TR200002784T2 (tr) 1998-03-11 2000-12-21 Endorecherche, Inc Tip 5 ve tip 3 17beta-Hidroksisteroid dehidrojenaz inhibitörleri ve bunların kullanımı için metodlar
US6465445B1 (en) 1998-06-11 2002-10-15 Endorecherche, Inc. Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors
US7005428B1 (en) 1998-06-11 2006-02-28 Endorecherche, Inc. Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors
DE60239207D1 (de) * 2001-08-10 2011-03-31 Takeda Pharmaceutical Gnrh-agonistische kombinationsmittel
AR036492A1 (es) 2001-09-06 2004-09-15 Schering Corp Inhibidores de la 17beta-hidroxiesteroide deshidrogenasa tipo 3, composiciones farmaceuticas y el uso de dichos inhibidores para la elaboracion de un medicamento para el tratamiento de enfermedades androgeno dependientes
MXPA04003611A (es) 2001-10-17 2004-07-30 Schering Corp Piperidina- y piperazinacetaminas como inhibidores de la 17 beta-hidroxiesteroide deshidrogenasa tipo 3 para el tratamiento de enfermedades androgeno-dependientes.
WO2004046111A1 (en) 2002-11-18 2004-06-03 Schering Corporation 17beta-hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases
MXPA05006485A (es) 2002-12-17 2005-08-26 Schering Corp Inhibidores de la 17 beta-hidroxiesteroide deshidrogenasa tipo 3 para el tratamiento de enfermedades dependientes de androgeno.
GB0513702D0 (en) 2005-07-04 2005-08-10 Sterix Ltd Compound
GB0722779D0 (en) 2007-11-20 2008-01-02 Sterix Ltd Compound
CN115862804B (zh) * 2022-11-25 2023-12-19 成都诺医德医学检验实验室有限公司 双药联用的联合用药的推荐方法及装置

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4329364A (en) * 1974-09-11 1982-05-11 Schering Corporation Antiandrogenic agents and methods for the treatment of androgen dependent disease states
FR2329276A1 (fr) * 1975-10-29 1977-05-27 Roussel Uclaf Nouvelles imidazolidines substituees, procede de preparation, application comme medicament et compositions les renfermant
DE2921593C2 (de) * 1979-05-28 1984-02-02 Gränges Nyby AB, Nybybruk Verfahren und Vorrichtung zum Weiterzerkleinern von hydriertem, grobstückigem Material, insbes. Schrott aus Titan oder dessen Legierungen
ZA822247B (en) * 1981-04-03 1983-11-30 Lilly Co Eli Benzothiophene compounds and process for preparing them

Also Published As

Publication number Publication date
EP0195015B1 (en) 1992-05-13
IE851929L (en) 1986-02-02
DK168516B1 (da) 1994-04-11
AU4728285A (en) 1986-03-07
AU594309B2 (en) 1990-03-08
DK147086A (da) 1986-04-01
DE3590389T1 (de) 1986-08-28
WO1986001105A1 (en) 1986-02-27
EP0195015A1 (en) 1986-09-24
ATE75947T1 (de) 1992-05-15
IE58836B1 (en) 1993-11-17
JPS62500451A (ja) 1987-02-26
DE3586053D1 (de) 1992-06-17
JPH0680016B2 (ja) 1994-10-12

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PBP Patent lapsed
B1 Patent granted (law 1993)
PUP Patent expired