DK1486571T3 - Fremgangsmåde til rekombinant fremstilling af polypeptider - Google Patents

Fremgangsmåde til rekombinant fremstilling af polypeptider

Info

Publication number
DK1486571T3
DK1486571T3 DK03012295T DK03012295T DK1486571T3 DK 1486571 T3 DK1486571 T3 DK 1486571T3 DK 03012295 T DK03012295 T DK 03012295T DK 03012295 T DK03012295 T DK 03012295T DK 1486571 T3 DK1486571 T3 DK 1486571T3
Authority
DK
Denmark
Prior art keywords
polypeptide
host cell
recombinant production
polypeptides
inclusion bodies
Prior art date
Application number
DK03012295T
Other languages
Danish (da)
English (en)
Inventor
Rainer Gruenbeck
Erhard Kopetzki
Friedrich Popp
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of DK1486571T3 publication Critical patent/DK1486571T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK03012295T 2003-06-12 2003-06-12 Fremgangsmåde til rekombinant fremstilling af polypeptider DK1486571T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP03012295A EP1486571B1 (de) 2003-06-12 2003-06-12 Verfahren zur rekombinanten Herstellung von Polypeptiden

Publications (1)

Publication Number Publication Date
DK1486571T3 true DK1486571T3 (da) 2006-04-18

Family

ID=33185854

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03012295T DK1486571T3 (da) 2003-06-12 2003-06-12 Fremgangsmåde til rekombinant fremstilling af polypeptider

Country Status (13)

Country Link
US (1) US7034119B2 (de)
EP (1) EP1486571B1 (de)
JP (1) JP3783963B2 (de)
KR (1) KR100614020B1 (de)
CN (1) CN1284850C (de)
AT (1) ATE312939T1 (de)
CA (1) CA2467142C (de)
DE (1) DE60302776T2 (de)
DK (1) DK1486571T3 (de)
ES (1) ES2253604T3 (de)
IL (1) IL161994A (de)
MX (1) MXPA04004934A (de)
TW (1) TWI282370B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008054673A (ja) * 2006-08-03 2008-03-13 Hokkaido Univ 組み換え蛋白質の製造方法
MX2013001539A (es) 2010-08-30 2013-03-18 Hoffmann La Roche Metodo para producir una particula de tetranectina-apolipoproteina a-1, la particula lipidica obtenida por el mismoy su uso.
RU2013111677A (ru) * 2010-08-30 2014-10-10 Ф. Хоффманн-Ля Рош Аг Конструкция для экспрессии у прокариот
RU2013112562A (ru) 2010-08-30 2014-10-10 Ф. Хоффманн-Ля Рош Аг Тетранектин-аполипопротеин а-i, содержащие его липидные частицы и его применение
DE102011118029A1 (de) * 2011-06-20 2012-12-20 Universität Leipzig Modifizierte antibiotische Peptide mit variabler systemischer Freisetzung
EP2748191A1 (de) 2011-08-25 2014-07-02 F.Hoffmann-La Roche Ag Verkürztes tetranectin-apolipoprotein-a-i-fusionsprotein, lipidpartikel damit und verwendungen davon
RU2014137621A (ru) 2012-02-29 2016-04-20 Ф.Хоффманн-Ля Рош Аг Способ уменьшения 1->2 сдвига рамки считывания
SI2959006T1 (sl) 2013-02-22 2018-10-30 F. Hoffmann-La Roche Ag Uporaba prokariontskega seva, ozdravljenega aminokislinske avksotrofije, za proizvodnjo rekombinantnega polipeptida
JP6576650B2 (ja) * 2015-03-03 2019-09-18 旭化成株式会社 グルコースの溶出抑制方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9215540D0 (en) * 1992-07-22 1992-09-02 Celltech Ltd Protein expression system
US6291245B1 (en) * 1998-07-15 2001-09-18 Roche Diagnostics Gmbh Host-vector system

Also Published As

Publication number Publication date
CN1572872A (zh) 2005-02-02
IL161994A0 (en) 2005-11-20
CA2467142C (en) 2008-01-15
EP1486571B1 (de) 2005-12-14
US7034119B2 (en) 2006-04-25
TWI282370B (en) 2007-06-11
EP1486571A1 (de) 2004-12-15
IL161994A (en) 2010-02-17
KR20040107397A (ko) 2004-12-20
ES2253604T3 (es) 2006-06-01
MXPA04004934A (es) 2005-08-10
CA2467142A1 (en) 2004-12-12
US20050003485A1 (en) 2005-01-06
DE60302776T2 (de) 2006-08-17
KR100614020B1 (ko) 2006-08-22
DE60302776D1 (de) 2006-01-19
JP3783963B2 (ja) 2006-06-07
CN1284850C (zh) 2006-11-15
JP2005000170A (ja) 2005-01-06
TW200510544A (en) 2005-03-16
ATE312939T1 (de) 2005-12-15

Similar Documents

Publication Publication Date Title
DK1422237T3 (da) Fremgangsmåder til rekombinant frembringelse af antifusogene peptider
CY1110494T1 (el) Μεταστροφες μεταβολικου ρυθμου σε ζυμωσεις που εκφραζουν ανασυνδυασμενες πρωτεϊνες
WO2004061122A3 (en) Cell proliferation-related polypeptides and uses therefor
SI1863920T1 (sl) Postopek za izboljšano izolacijo rekombinantno proizvedenih proteinov
WO2006136831A3 (en) Gene expression technique
DK1486571T3 (da) Fremgangsmåde til rekombinant fremstilling af polypeptider
ATE454444T1 (de) Verfahren zur herstellung rekombinanter proteine
DK1897939T3 (da) Mikroorganismestamme til produktion af rekombinante proteiner
WO2005058945A3 (de) Genvarianten die für proteine aus dem stoffwechselweg von feinchemikalien kodieren
WO2006053021A3 (en) Methods for engineering polypeptide variants via somatic hypermutation and polypeptides made thereby
DK1819816T3 (da) Fremgangsmåder til fremstilling og udskillelse af modificerede peptider
WO2004111194A3 (en) Method to increase protein production in culture
WO2001075132A3 (en) Method for producing authentic cytokines in plants
WO2004024898A3 (en) Nematode fatty acid desaturase-like sequences
WO2006018205A3 (de) Neue essentielle gene von bacillus licheniformis und darauf aufbauende verbesserte biotechnologische produktionsverfahren
Laborde et al. Overexpression of ovine leptin in Pichia pastoris: physiological yeast response to leptin production and characterization of the recombinant hormone
WO2004078915A3 (en) Cell culture
WO2003042693A3 (en) Method for measuring intracellular atp and/or gene expression
DK1639119T3 (da) Fremgangsmåde til mikrobiologisk isomerisering af alpha-hydroxycarboxylsyrer
Ota et al. A parallel affinity purification method for selective isolation of polyubiquitinated proteins
NO20010246L (no) Fremgangsmåte for fremstilling av proteiner i transformerte gjærceller
SE9904247D0 (sv) Compositions and methods utilizing sequences for controlling nucleic acid expression in yeast
WO2005014807A3 (en) Moss expressing promoting regions
ATE403863T1 (de) Verfahren zum nachweis von intrazellulären atp und/oder genexpression
JO2429B1 (en) Ways to produce recombinant peptides of antigen - merger