ATE202381T1 - Neue prosequenz zur sekretion heterologer proteine aus hefezellen - Google Patents

Neue prosequenz zur sekretion heterologer proteine aus hefezellen

Info

Publication number
ATE202381T1
ATE202381T1 AT94400062T AT94400062T ATE202381T1 AT E202381 T1 ATE202381 T1 AT E202381T1 AT 94400062 T AT94400062 T AT 94400062T AT 94400062 T AT94400062 T AT 94400062T AT E202381 T1 ATE202381 T1 AT E202381T1
Authority
AT
Austria
Prior art keywords
new
secretion
proteins
pro sequence
heterologue
Prior art date
Application number
AT94400062T
Other languages
English (en)
Inventor
Tilman Achstetter
Original Assignee
Transgene Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Transgene Sa filed Critical Transgene Sa
Application granted granted Critical
Publication of ATE202381T1 publication Critical patent/ATE202381T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/555Interferons [IFN]
    • C07K14/56IFN-alpha
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43563Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
    • C07K14/43577Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects from flies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • C07K14/815Protease inhibitors from leeches, e.g. hirudin, eglin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Insects & Arthropods (AREA)
  • Wood Science & Technology (AREA)
  • Mycology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
AT94400062T 1993-01-11 1994-01-11 Neue prosequenz zur sekretion heterologer proteine aus hefezellen ATE202381T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9300171A FR2700338B1 (fr) 1993-01-11 1993-01-11 Nouvelle séquence pro permettant la secrétion de protéines hétérologues à partir d'une cellule de levure.

Publications (1)

Publication Number Publication Date
ATE202381T1 true ATE202381T1 (de) 2001-07-15

Family

ID=9442934

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94400062T ATE202381T1 (de) 1993-01-11 1994-01-11 Neue prosequenz zur sekretion heterologer proteine aus hefezellen

Country Status (8)

Country Link
EP (1) EP0607080B1 (de)
AT (1) ATE202381T1 (de)
DE (1) DE69427496T2 (de)
DK (1) DK0607080T3 (de)
ES (1) ES2157963T3 (de)
FR (1) FR2700338B1 (de)
GR (1) GR3036648T3 (de)
PT (1) PT607080E (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2714908A1 (fr) * 1994-01-11 1995-07-13 Transgene Sa Famille de peptides appelés xénoxines.
DK0706567T3 (da) * 1993-06-29 2001-09-17 Transgene Sa Peptidfamilie betegnet xenoxiner
CN1062017C (zh) * 1995-09-01 2001-02-14 中国科学院遗传研究所 防御素基因的植物表达载体质粒
GB9724307D0 (en) * 1997-11-17 1998-01-14 Zeneca Ltd Improvements relating to protein accumulation
FR2777568B1 (fr) 1998-04-15 2002-10-31 Rhone Poulenc Agrochimie Gene codant pour l'heliomicine, proteine obtenue, vecteur le contenant, organismes transformes obtenus et procede de preparation
RU2460795C1 (ru) * 2011-07-06 2012-09-10 Федеральное государственное унитарное предприятие "Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов" (ФГУП "ГосНИИгенетика") Способ микробиологического синтеза секретируемого соматотропина человека и штамм дрожжей saccharomyces cerevisiae - продуцент секретируемого соматотропина человека

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL83435A (en) * 1986-09-23 1993-01-14 Miles Lab Dna construct for expression of genes in yeast, an expression vector containing it and yeast transformed with said expression vector
FR2633296B1 (fr) * 1988-06-24 1991-11-15 Centre Nat Rech Scient Molecules peptidiques a action sur les germes a gram positif
FR2646437B1 (fr) * 1989-04-28 1991-08-30 Transgene Sa Nouvelles sequences d'adn, leur application en tant que sequence codant pour un peptide signal pour la secretion de proteines matures par des levures recombinantes, cassettes d'expression, levures transformees et procede de preparation de proteines correspondant

Also Published As

Publication number Publication date
DK0607080T3 (da) 2001-10-01
ES2157963T3 (es) 2001-09-01
EP0607080A1 (de) 1994-07-20
EP0607080B1 (de) 2001-06-20
FR2700338A1 (fr) 1994-07-13
FR2700338B1 (fr) 1995-03-31
DE69427496T2 (de) 2002-06-06
DE69427496D1 (de) 2001-07-26
PT607080E (pt) 2001-10-31
GR3036648T3 (en) 2001-12-31

Similar Documents

Publication Publication Date Title
KR920012442A (ko) 피치아 파스토리스 산성 인산효소 유전자의 dna 단편 및 이를 사용하는 방법
DE69922978D1 (de) Transformationsystem in filamentösen fungiziden chrysosporium-wirtszellen
ES532825A0 (es) Un metodo de sintetizar un polipeptido seleccionado
AU2002243190A1 (en) Phosphatase stress-related proteins and methods of use in plants
AU2734001A (en) Protein kinase stress-related proteins and methods of use in plants
DK0894126T3 (da) Alkalisk phosphatase-deficient trådformet svamp
BG46159A3 (bg) Метод за получаване на протеин,хетероложен на дрожден микроорганизъм
ATE77104T1 (de) Menge und verfahren zur herstellung rekombinierter erzeugnisse in grosser ausbeute.
IE811715L (en) Urogastrone gene, plasmid recombinants, transformed cells
FI970200A0 (fi) Termofiilinen sieniekspressiojärjestelmä
DK1332222T3 (da) Stofskifteændringer i fermenteringer der udtrykker rekombinante proteiner
ATA192895A (de) Herstellung von proteinen aus pro-proteinen durch fusionsproteine abgeleitet von furin oder furinanalogen
ATE202381T1 (de) Neue prosequenz zur sekretion heterologer proteine aus hefezellen
ATE117371T1 (de) Saccharomyces-cerevisiae-stamm, der ein heterologes protein produziert, und verfahren zur herstellung dieses heterologen proteins durch fermentation dieses stammes.
DK620084D0 (da) Fremgangsmaade til fremstilling af ethanol
DK0396436T3 (da) Gærstammer til fremstilling af modne heterologe proteiner, især hirudin
ATE312939T1 (de) Verfahren zur rekombinanten herstellung von polypeptiden
EE03074B1 (et) Rekombinantsed eukarüootsed rakud, nende saamiseks vajalikud DNA järjestused, meetod eukarüootsete rakkude konstrueerimiseks ja sekreteeritavate valkude ning biomassi tootmismeetod
ATE220104T1 (de) Expressionssystem zur produktion von proteinen
WO2002002771A3 (en) Human sparc-homologous (hsparc-h1) gene and methods and uses thereof
KR900003370A (ko) 인간 췌장 포스포리파제 a₂의 제조방법
WO2004046359A3 (en) Method of controlling gene expression in plants or plant cells
ATE288495T1 (de) Phosphoglycerat-kinase-1-promotor aus rhizopus oryzae und dessen verwendung
DE60024596D1 (de) Sequenzen zur verbesserung der sekretionseffizienz von nicht-sekretierten proteinen in säugetier- und insektenzellen
ATE470700T1 (de) Bazillus zelle für die herstellung von proteinen

Legal Events

Date Code Title Description
REN Ceased due to non-payment of the annual fee