DK153406C - Poroest, uorganisk stoettemateriale, der er belagt med en organisk, stationaer fase, til anvendelse i kromatografi og fremgangsmaade til dets fremstilling - Google Patents

Poroest, uorganisk stoettemateriale, der er belagt med en organisk, stationaer fase, til anvendelse i kromatografi og fremgangsmaade til dets fremstilling

Info

Publication number
DK153406C
DK153406C DK282681A DK282681A DK153406C DK 153406 C DK153406 C DK 153406C DK 282681 A DK282681 A DK 282681A DK 282681 A DK282681 A DK 282681A DK 153406 C DK153406 C DK 153406C
Authority
DK
Denmark
Prior art keywords
chromatography
organic
stationary phase
poroest
inorganic
Prior art date
Application number
DK282681A
Other languages
English (en)
Other versions
DK153406B (da
DK282681A (da
Inventor
Jan Andre Jozef Schutijser
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nv filed Critical Akzo Nv
Publication of DK282681A publication Critical patent/DK282681A/da
Publication of DK153406B publication Critical patent/DK153406B/da
Application granted granted Critical
Publication of DK153406C publication Critical patent/DK153406C/da

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26Synthetic macromolecular compounds
    • B01J20/261Synthetic macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26Synthetic macromolecular compounds
    • B01J20/264Synthetic macromolecular compounds derived from different types of monomers, e.g. linear or branched copolymers, block copolymers, graft copolymers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26Synthetic macromolecular compounds
    • B01J20/265Synthetic macromolecular compounds modified or post-treated polymers
    • B01J20/267Cross-linked polymers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28054Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
    • B01J20/28057Surface area, e.g. B.E.T specific surface area
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28054Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
    • B01J20/28078Pore diameter
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B01J20/289Phases chemically bonded to a substrate, e.g. to silica or to polymers bonded via a spacer
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30Processes for preparing, regenerating, or reactivating
    • B01J20/3092Packing of a container, e.g. packing a cartridge or column
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30Processes for preparing, regenerating, or reactivating
    • B01J20/32Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3204Inorganic carriers, supports or substrates
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30Processes for preparing, regenerating, or reactivating
    • B01J20/32Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3214Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating
    • B01J20/3217Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30Processes for preparing, regenerating, or reactivating
    • B01J20/32Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3214Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating
    • B01J20/3217Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond
    • B01J20/3219Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond involving a particular spacer or linking group, e.g. for attaching an active group
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30Processes for preparing, regenerating, or reactivating
    • B01J20/32Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3244Non-macromolecular compounds
    • B01J20/3246Non-macromolecular compounds having a well defined chemical structure
    • B01J20/3257Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one of the heteroatoms nitrogen, oxygen or sulfur together with at least one silicon atom, these atoms not being part of the carrier as such
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30Processes for preparing, regenerating, or reactivating
    • B01J20/32Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3244Non-macromolecular compounds
    • B01J20/3246Non-macromolecular compounds having a well defined chemical structure
    • B01J20/3257Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one of the heteroatoms nitrogen, oxygen or sulfur together with at least one silicon atom, these atoms not being part of the carrier as such
    • B01J20/3263Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one of the heteroatoms nitrogen, oxygen or sulfur together with at least one silicon atom, these atoms not being part of the carrier as such comprising a cyclic structure containing at least one of the heteroatoms nitrogen, oxygen or sulfur, e.g. an heterocyclic or heteroaromatic structure
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30Processes for preparing, regenerating, or reactivating
    • B01J20/32Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268Macromolecular compounds
    • B01J20/327Polymers obtained by reactions involving only carbon to carbon unsaturated bonds
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30Processes for preparing, regenerating, or reactivating
    • B01J20/32Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268Macromolecular compounds
    • B01J20/3276Copolymers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30Processes for preparing, regenerating, or reactivating
    • B01J20/32Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268Macromolecular compounds
    • B01J20/328Polymers on the carrier being further modified
    • B01J20/3282Crosslinked polymers
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F292/00Macromolecular compounds obtained by polymerising monomers on to inorganic materials
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00Aspects relating to sorbent materials
    • B01J2220/50Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/54Sorbents specially adapted for analytical or investigative chromatography
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00Aspects relating to sorbent materials
    • B01J2220/50Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/58Use in a single column
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/29Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991Coated
    • Y10T428/2993Silicic or refractory material containing [e.g., tungsten oxide, glass, cement, etc.]
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/29Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991Coated
    • Y10T428/2993Silicic or refractory material containing [e.g., tungsten oxide, glass, cement, etc.]
    • Y10T428/2995Silane, siloxane or silicone coating
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/31504Composite [nonstructural laminate]
    • Y10T428/31652Of asbestos
    • Y10T428/31663As siloxane, silicone or silane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Graft Or Block Polymers (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Polymerisation Methods In General (AREA)
  • Pigments, Carbon Blacks, Or Wood Stains (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Ceramic Products (AREA)
  • Laminated Bodies (AREA)
DK282681A 1980-06-27 1981-06-26 Poroest, uorganisk stoettemateriale, der er belagt med en organisk, stationaer fase, til anvendelse i kromatografi og fremgangsmaade til dets fremstilling DK153406C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL8003727 1980-06-27
NL8003727 1980-06-27

Publications (3)

Publication Number Publication Date
DK282681A DK282681A (da) 1981-12-28
DK153406B DK153406B (da) 1988-07-11
DK153406C true DK153406C (da) 1988-11-28

Family

ID=19835525

Family Applications (1)

Application Number Title Priority Date Filing Date
DK282681A DK153406C (da) 1980-06-27 1981-06-26 Poroest, uorganisk stoettemateriale, der er belagt med en organisk, stationaer fase, til anvendelse i kromatografi og fremgangsmaade til dets fremstilling

Country Status (13)

Country Link
US (1) US4415631A (da)
EP (1) EP0043159B1 (da)
JP (1) JPS5738937A (da)
AT (1) ATE15378T1 (da)
AU (1) AU548877B2 (da)
CA (1) CA1170643A (da)
DE (1) DE3172131D1 (da)
DK (1) DK153406C (da)
ES (1) ES8303463A1 (da)
FI (1) FI68636C (da)
GR (1) GR74357B (da)
IE (1) IE51337B1 (da)
ZA (1) ZA814216B (da)

Families Citing this family (86)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58202043A (ja) * 1982-05-19 1983-11-25 Sumitomo Chem Co Ltd グラフトしたクロマトグラフ充填剤およびそれを用いる鏡像体混合物の分析法
US4560704A (en) * 1982-11-12 1985-12-24 Purdue Research Foundation Polyamine based bonded phase chromatography
JPS59193141A (ja) * 1983-04-18 1984-11-01 Asahi Chem Ind Co Ltd 新規複合体とその製法
DE3328348A1 (de) * 1983-08-05 1985-02-14 Degussa Ag, 6000 Frankfurt Verfahren zur duennschichtchromatographischen trennung von enantiomeren
EP0143369B2 (en) * 1983-11-25 1997-09-24 Asahi Kasei Kogyo Kabushiki Kaisha A porous adsorbent for adsorbing low density lipoproteins
US4724207A (en) * 1984-02-02 1988-02-09 Cuno Incorporated Modified siliceous chromatographic supports
CA1253129A (en) * 1984-02-09 1989-04-25 Thomas R. Jones Porous inorganic materials
US4523997A (en) * 1984-03-02 1985-06-18 J. T. Baker Chemical Company Affinity chromatography matrix with built-in reaction indicator
US4782040A (en) * 1984-04-09 1988-11-01 Dow Corning Corporation Porous materials having a dual surface
US4600646A (en) * 1984-08-15 1986-07-15 E. I. Du Pont De Nemours And Company Metal oxide stabilized chromatography packings
JPS61210956A (ja) * 1985-03-15 1986-09-19 Cosmo Co Ltd クロマトグラフイ−用薄層棒
JPS6210005A (ja) * 1985-07-08 1987-01-19 Nippon Shiken Kogyo Kk 抗歯髄等組織刺激性及び抗為害性組成物
US4793920A (en) * 1985-12-11 1988-12-27 Lee Scientific, Inc. Chromatography columns with cast porous plugs and methods of fabricating same
US4927749A (en) * 1986-04-09 1990-05-22 Jeanette Simpson Reagent for cell separation
US4927750A (en) * 1986-04-09 1990-05-22 Jeanette Simpson Cell separation process
DE3619303A1 (de) * 1986-06-07 1987-12-10 Merck Patent Gmbh Optisch aktive adsorbentien
JP2504005B2 (ja) * 1986-11-17 1996-06-05 東ソー株式会社 充填剤およびその製法
US5000848A (en) * 1987-01-28 1991-03-19 Membrex, Inc. Rotary filtration device with hyperphilic membrane
US4906379A (en) * 1987-01-28 1990-03-06 Membrex, Inc. Hydrophilic article and method of producing same
CA1339812C (en) * 1988-02-19 1998-04-14 Tamami Koyama Filler for measuring enzyme activity, column packed with the filler, andmethod of measuring enzyme activity by using the column
US4919804A (en) * 1988-03-01 1990-04-24 University Of Florida Ultrasound driven synthesis of reversed and normal phase stationary phases for liquid chromatography
DE3811042A1 (de) * 1988-03-31 1989-10-19 Merck Patent Gmbh Ionenaustauscher
IL87004A (en) * 1988-07-06 1992-08-18 Technion Res & Dev Foundation Method and apparatus for bioaffinity separation
CA1327023C (en) * 1988-07-27 1994-02-15 Leonard T. Hodgins Rotary filtration device with hyperphilic membrane
US4957620A (en) * 1988-11-15 1990-09-18 Hoechst Celanese Corporation Liquid chromatography using microporous hollow fibers
US5645717A (en) * 1989-01-13 1997-07-08 Bio-Rad Laboratories, Inc. Hydrophobic polymers from water-soluble monomers and their use as chromatography media
JPH0678347B2 (ja) * 1989-01-13 1994-10-05 信越化学工業株式会社 有機けい素化合物
US5770416A (en) * 1989-05-26 1998-06-23 Upfront Chromatography A/S Permeable hollow particles having an outer shell of mechanically rigid porous material
DK259789D0 (da) * 1989-05-26 1989-05-26 Kem En Tec Ltd Aps Partikulaert materiale
US5053133A (en) * 1990-02-09 1991-10-01 Elias Klein Affinity separation with activated polyamide microporous membranes
US5211993A (en) * 1990-12-10 1993-05-18 Advanced Surface Technology, Inc. Method of making novel separation media
US5470463A (en) * 1992-06-19 1995-11-28 Sepracor Inc. Passivated porous supports and methods for the preparation and use of same
US5445732A (en) * 1992-06-19 1995-08-29 Sepracor Inc. Passivated porous polymer supports and methods for the preparation and use of same
US5906734A (en) * 1992-06-19 1999-05-25 Biosepra Inc. Passivated porous polymer supports and methods for the preparation and use of same
US5268097A (en) * 1992-06-19 1993-12-07 Sepracor Inc. Passivated and stabilized porous mineral oxide supports and method for the preparation and use of same
US5641403A (en) * 1993-07-16 1997-06-24 Merck Patent Gesellschaft Mit Beschrankter Haftung Separating materials for hydrophobic chromatography
DE4333674A1 (de) * 1993-10-02 1995-04-06 Merck Patent Gmbh Nukleotidhaltiges Sorbens für die Affinitätschromatographie
DE4333821A1 (de) * 1993-10-04 1995-04-06 Merck Patent Gmbh Ionenaustauscher
DE4334353A1 (de) * 1993-10-08 1995-04-13 Merck Patent Gmbh Verfahren und Träger für die Gelpermeationschromatographie
US5374339A (en) * 1993-10-14 1994-12-20 Guillet; James E. Production of hydrogen peroxide
US5547760A (en) 1994-04-26 1996-08-20 Ibc Advanced Technologies, Inc. Compositions and processes for separating and concentrating certain ions from mixed ion solutions using ion-binding ligands bonded to membranes
US5633085A (en) * 1994-06-10 1997-05-27 Potters Industries Inc. Durable composite particle and method of making same
US5906747A (en) * 1995-11-13 1999-05-25 Biosepra Inc. Separation of molecules from dilute solutions using composite chromatography media having high dynamic sorptive capacity at high flow rates
JP2862509B2 (ja) * 1996-05-28 1999-03-03 東洋電化工業株式会社 リパーゼ固定化用担体及び固定化リパーゼ
US5935429A (en) * 1997-01-03 1999-08-10 Bio-Rad Laboratories, Inc. Chromatography columns with continuous beds formed in situ from aqueous solutions
SE9700769D0 (sv) * 1997-03-04 1997-03-04 Pharmacia Biotech Ab Matriser för separation och separation som utnyttjar matriserna
US6156431A (en) * 1999-01-04 2000-12-05 United Chemical Technologies, Inc. Extraction material comprising treated silica and method for determination of gamma-hydroxybutyrate
US6689715B1 (en) * 2000-02-09 2004-02-10 Hammen Corporation Tethered polymer ligands
US6994791B2 (en) * 2002-06-27 2006-02-07 Akzo Nobel N.V. Adsorbent material and method of preparing an adsorbent material
EP1515800A1 (en) * 2002-06-27 2005-03-23 Akzo Nobel N.V. Adsorbent material and method of preparing an adsorbent material
EP1552013A1 (en) * 2002-07-26 2005-07-13 Applera Corporation Microfluidic device including purification column with excess diluent, and method
US8137548B2 (en) * 2003-10-17 2012-03-20 Zirchrom Separations, Inc. Chelator-modified inorganic oxide particles
JP3922648B2 (ja) * 2004-05-24 2007-05-30 株式会社資生堂 アフィニティー粒子及びアフィニティー分離方法
US7402243B2 (en) 2004-09-10 2008-07-22 Dionex Corporation Organosilanes and substrate bonded with same
US7468130B2 (en) * 2005-02-15 2008-12-23 Dionex Corporation Organosilanes and substrates covalently bonded with same and methods for synthesis and use same
FR2889078B1 (fr) * 2005-07-27 2007-11-02 Aventis Pharma Sa Nouvelle methode de chromatographie d'affinite d'antithrombine iii
US20070089604A1 (en) * 2005-10-20 2007-04-26 Wu Chen Novel chromatographic stationary phase
DE102006061327A1 (de) * 2006-12-22 2008-06-26 Basf Construction Polymers Gmbh Pfropf-Copolymer, Verfahren zu dessen Herstellung und seine Verwendung
WO2008106043A2 (en) * 2007-02-26 2008-09-04 Alltech Associates Inc. Ultra-fast chromatography
WO2008131026A1 (en) * 2007-04-16 2008-10-30 James Hardie International Finance B.V. Light weight additive, method of making and uses thereof
US7557232B2 (en) * 2007-05-25 2009-07-07 Dionex Corporation Compositions useful as chromatography stationary phases
JP5421900B2 (ja) * 2008-03-19 2014-02-19 株式会社 資生堂 アフィニティー粒子の製造方法
RU2470041C2 (ru) * 2008-05-21 2012-12-20 Басф Се Привитой сополимер, способ его получения и его применение
WO2010141426A1 (en) 2009-06-01 2010-12-09 Waters Technologies Corporation Hybrid material for chromatographic separations
US11439977B2 (en) 2009-06-01 2022-09-13 Waters Technologies Corporation Hybrid material for chromatographic separations comprising a superficially porous core and a surrounding material
US9272260B2 (en) * 2009-08-14 2016-03-01 University Of Louisville Research Foundation, Inc. Methods of synthesis and purification by use of a solid support
US20130112605A1 (en) 2010-07-26 2013-05-09 Waters Technologies Corporation Superficially porous materials comprising a substantially nonporous core having narrow particle size distribution; process for the preparation thereof; and use thereof for chromatographic separations
JP6223347B2 (ja) * 2011-11-01 2017-11-01 パーデュー・リサーチ・ファウンデーションPurdue Research Foundation 親水性コポリマーコーティングを有するタンパク質クロマトグラフィーマトリックス
US9669402B2 (en) * 2012-03-08 2017-06-06 Bio-Rad Laboratories, Inc. Anionic exchange-hydrophobic mixed mode
WO2013173501A2 (en) 2012-05-15 2013-11-21 Waters Technologies Corporation Chromatographic materials
EP2811983B1 (en) * 2012-09-17 2019-05-01 W.R. Grace & CO. - CONN. Functionalized particulate support material and methods of making and using the same
EP2812091B1 (en) 2012-09-17 2021-03-10 W.R. Grace & CO. - CONN. Chromatography media and devices
US9610576B2 (en) * 2012-09-27 2017-04-04 Agilent Technologies, Inc. Hydrolytically stable ion-exchange stationary phases and uses thereof
WO2014061411A1 (ja) * 2012-10-18 2014-04-24 Jnc株式会社 抗体精製用陽イオン交換クロマトグラフィー担体および抗体医薬の製造過程で生産される抗体単量体とその重合体の分離方法
WO2014201033A1 (en) * 2013-06-11 2014-12-18 Waters Technologies Corporation Chromatographic columns and separation devices comprising a superficially porous material; and use thereof for supercritical fluid chromatography and other chromatography
US9518960B2 (en) * 2013-10-02 2016-12-13 Waters Technologies Corporation System and method for rapid analysis of polycyclic aromatic hydrocarbons
EP3084058B1 (en) * 2013-12-19 2017-11-08 3M Innovative Properties Company Laminated articles for microbial removal and low pressure drop filtration, methods of making, and methods of using same
ES2887110T3 (es) 2014-01-16 2021-12-21 Grace W R & Co Medios para cromatografía de afinidad y dispositivos para cromatografía
WO2015133507A1 (ja) * 2014-03-05 2015-09-11 Jsr株式会社 固相担体、リガンド結合固相担体、標的物質の検出又は分離方法、固相担体の製造方法、及びリガンド結合固相担体の製造方法
PL3137209T3 (pl) 2014-05-02 2023-01-02 W.R. Grace & Co. - Conn. Funkcjonalizowany materiał nośnikowy i sposoby wytwarzania oraz stosowania funkcjonalizowanego materiału nośnikowego
KR102566292B1 (ko) 2015-06-05 2023-08-10 더블유.알. 그레이스 앤드 캄파니-콘. 흡착성 바이오프로세싱 정화제와 이의 제조 및 사용 방법
US20190015815A1 (en) 2016-03-06 2019-01-17 Waters Technologies Corporation Superficially porous materials comprising a coated core having narrow particle size distribution; process for the preparation thereof; and use thereof for chromatographic separations
BR112018075607B1 (pt) * 2016-07-14 2022-08-30 Akzo Nobel Chemicals International B.V Processo para a fabricação de microesferas termoplásticas termicamente expansíveis, processo para produção de microesferas expandidas, microesferas termoplásticas termicamente expansíveis obteníveis pelo processo, microesferas expandidas, produto fabricado, e uso de uma sílica coloidal que é modificada pela superfície com pelo menos grupos organossilanos hidrofóbicos
CN116569043A (zh) * 2020-11-13 2023-08-08 科罗拉多大学董事会法人团体 固定化的酶的稳定性和活性
US20250073647A1 (en) * 2023-08-28 2025-03-06 Cytiva Us Llc Diethylamino ethyl polymers and methods of use
US12434218B2 (en) * 2023-11-28 2025-10-07 Phenomenex, Inc. Pore structure for separation of adeno-associated viruses (AAVS) from their aggregates

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2078974A5 (da) * 1970-02-25 1971-11-05 Hoffmann La Roche
US3799799A (en) * 1971-04-01 1974-03-26 Fiberglas Canada Ltd Coating of mica reinforcement for composite materials
US3984349A (en) * 1971-07-26 1976-10-05 Societe Rhone-Progil Modified porous bodies
GB1456974A (en) * 1973-01-10 1976-12-01 Nat Res Dev Ion exchange materials
GB1456865A (en) * 1973-12-14 1976-12-01 Pye Ltd Method of bonding copolymers
US3983299A (en) * 1974-03-04 1976-09-28 Purdue Research Foundation Bonded carbohydrate stationary phases for chromatography
SE7712058L (sv) * 1976-11-12 1978-05-13 Ceskoslovenska Akademie Ved Tredimensionell berare av oorganiskt, porost material och en reaktiv polymer och ett forfarande for framstellning derav
JPS5383680A (en) * 1976-12-29 1978-07-24 Toray Silicone Co Filler for gas separation column
JPS54137398A (en) * 1978-04-18 1979-10-25 Sekisui Chemical Co Ltd Filled material for liquid chromatography

Also Published As

Publication number Publication date
CA1170643A (en) 1984-07-10
US4415631A (en) 1983-11-15
DK153406B (da) 1988-07-11
DE3172131D1 (en) 1985-10-10
EP0043159A1 (en) 1982-01-06
EP0043159B1 (en) 1985-09-04
JPS6216133B2 (da) 1987-04-10
ATE15378T1 (de) 1985-09-15
AU7231681A (en) 1982-01-07
FI812002L (fi) 1981-12-28
IE811394L (en) 1981-12-27
JPS5738937A (en) 1982-03-03
IE51337B1 (en) 1986-12-10
FI68636B (fi) 1985-06-28
FI68636C (fi) 1985-10-10
DK282681A (da) 1981-12-28
ZA814216B (en) 1982-07-28
AU548877B2 (en) 1986-01-09
GR74357B (da) 1984-06-27
ES503455A0 (es) 1982-12-16
ES8303463A1 (es) 1983-02-16

Similar Documents

Publication Publication Date Title
DK153406C (da) Poroest, uorganisk stoettemateriale, der er belagt med en organisk, stationaer fase, til anvendelse i kromatografi og fremgangsmaade til dets fremstilling
EP0386926A3 (en) Silica gel supports suitable for chromatographic separations
US4118316A (en) Quaternized siliceous supports for gel permeation chromatography
ATE53307T1 (de) Mit polyethylenimid gebundene packung fuer chromatographie.
IE43952L (en) Composition having affinity for hepatitis virus
EA200200837A1 (ru) Полипептиды, повышающие эффективность генного переноса в клетки-мишени с помощью ретровируса, и гены, их кодирующие
DK361488D0 (da) Fremgangsmaade til indhylling af granulater
SE7909262L (sv) Fixering av toxiska material genom jonbyte i en glasmatrix
EP0597503A3 (en) ECK receptor ligands.
GB1511969A (en) Dextran derivative gel for use in electrophoretic separation processes
DE2966596D1 (en) Improvements in or relating to media for affinity chromatography
GB1506226A (en) Method of chemically modifying the surface of solids
SE8700949L (sv) Adsorbent for affinitetskromatografi
EP0194578A3 (en) Proteins immobilised on polyamides or cellulose hydrate and the use thereof for the preparation of biocatalysts, test strips or chromatography materials
DK535383D0 (da) Vinylencarbonat-polymerisat samt fremgangsmade til dets fremstilling og dets anvendelse
EP0295808A3 (en) Liquid chromatography packing materials and method for making and using same
NO180558C (no) Ligandholdig medium for kromatografisk adsorpsjon, fremgangsmåte for fremstilling av mediet, samt anvendelse av mediet
JPS57197034A (en) Preparation of immobilized nucleic acid
KR910009283A (ko) 백일해 독소 및 또는 사상혈구 응집소 항원의 정제 방법(Process)
DE3476457D1 (en) Method for the detection of an oligomer in a liquid medium containing corresponding monomers, device for use with the method, and its application, especially with respect to the detection of allergens
FR2422699A1 (fr) Procede de preparation d'un materiau solide poreux revetu de cellulose ou de cellulose modifiee
EP0113452A3 (en) Magnetic particles as supports for organic synthesis
DK544085A (da) Fremgangsmaade til fremstilling af paa en baerer immobiliserede, hoejaktive, biologisk virksomme forbindelser
ATE13192T1 (de) Perlpolymerisat und dessen verwendung zur immobilisierung von enzymen.
SU857860A1 (ru) Способ получени сорбента дл хроматографии

Legal Events

Date Code Title Description
PUP Patent expired