DK1545546T3 - Behandling af dyskinesi med 2,3-benzodiazepiner - Google Patents

Behandling af dyskinesi med 2,3-benzodiazepiner

Info

Publication number: DK1545546T3
Authority: DK; Denmark
Prior art keywords: dyskinesia; benzodiazepines; treatment; pakinsonism; nerisopam
Prior art date: 2002-09-13

Application number

DK03795090T

Other languages

English (en)

Inventor

Alan Crossman

Michael Motac Hill

Jonathan Brotchie

Original Assignee

Motac Neuroscience Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-09-13

Filing date

2003-09-11

Publication date

2007-08-06

2002-09-13 Priority claimed from GB0221248A external-priority patent/GB0221248D0/en

2003-02-25 Priority claimed from GB0304227A external-priority patent/GB0304227D0/en

2003-09-11 Application filed by Motac Neuroscience Ltd filed Critical Motac Neuroscience Ltd

2007-08-06 Application granted granted Critical

2007-08-06 Publication of DK1545546T3 publication Critical patent/DK1545546T3/da

Links

208000012661 Dyskinesia Diseases 0.000 title abstract 3
RPBDCDQMCRHNLM-UHFFFAOYSA-N C1=NNC=C2C=CC=CC2=C1 Chemical class C1=NNC=C2C=CC=CC2=C1 RPBDCDQMCRHNLM-UHFFFAOYSA-N 0.000 title abstract 2
RUJBDQSFYCKFAA-UHFFFAOYSA-N Tofisopam Chemical compound N=1N=C(C)C(CC)C2=CC(OC)=C(OC)C=C2C=1C1=CC=C(OC)C(OC)=C1 RUJBDQSFYCKFAA-UHFFFAOYSA-N 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
VQYLGVVODFDFNK-UHFFFAOYSA-N girisopam Chemical compound C1=2C=C(OC)C(OC)=CC=2CC(C)=NN=C1C1=CC=CC(Cl)=C1 VQYLGVVODFDFNK-UHFFFAOYSA-N 0.000 abstract 1
229950002157 girisopam Drugs 0.000 abstract 1
WWQDEXGFYVSTCX-UHFFFAOYSA-N nerisopam Chemical compound C1=2C=C(OC)C(OC)=CC=2CC(C)=NN=C1C1=CC=C(N)C=C1 WWQDEXGFYVSTCX-UHFFFAOYSA-N 0.000 abstract 1
229950001811 nerisopam Drugs 0.000 abstract 1
238000002560 therapeutic procedure Methods 0.000 abstract 1
229960002501 tofisopam Drugs 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Chemical Kinetics & Catalysis (AREA)
Psychology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DK03795090T 2002-09-13 2003-09-11 Behandling af dyskinesi med 2,3-benzodiazepiner DK1545546T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GB0221248A GB0221248D0 (en)	2002-09-13	2002-09-13	Treatment of basal ganglia-related movement disorders
GB0304227A GB0304227D0 (en)	2003-02-25	2003-02-25	Treatment of basal ganglia-related movement disorders
PCT/GB2003/003951 WO2004024163A1 (en)	2002-09-13	2003-09-11	Treatment of basal ganglia-related movement disorders with 2,3-benzodiazepines

Publications (1)

Publication Number	Publication Date
DK1545546T3 true DK1545546T3 (da)	2007-08-06

Family

ID=31995700

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK03795090T DK1545546T3 (da)	2002-09-13	2003-09-11	Behandling af dyskinesi med 2,3-benzodiazepiner

Country Status (13)

Country	Link
US (1)	US20050261282A1 (da)
EP (1)	EP1545546B1 (da)
JP (1)	JP4630665B2 (da)
CN (1)	CN1681512B (da)
AT (1)	ATE358488T1 (da)
AU (1)	AU2003263357B2 (da)
CA (1)	CA2498735C (da)
CY (1)	CY1106689T1 (da)
DE (1)	DE60313005T2 (da)
DK (1)	DK1545546T3 (da)
ES (1)	ES2285245T3 (da)
PT (1)	PT1545546E (da)
WO (1)	WO2004024163A1 (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9924941D0 (en) *	1999-10-22	1999-12-22	Univ Manchester	Treatment of dyskinesia
CN102836162A (zh) *	2012-04-10	2012-12-26	珠海亿邦制药股份有限公司	一种以托非索泮为活性成分的口服固体制剂及其应用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HU179018B (en) *	1978-10-19	1982-08-28	Gyogyszerkutato Intezet	Process for producing new 5h-2,3-benzodiazepine derivatives
US4452808A (en) *	1982-12-07	1984-06-05	Smithkline Beckman Corporation	4-Aminoalkyl-2(3H)-indolones
US4582916A (en) *	1983-09-26	1986-04-15	Mcneilab, Inc.	Chlorosulfate and azidosulfate esters of tetrahydro-2H-pyran-2-yl-methanol
US4513006A (en) *	1983-09-26	1985-04-23	Mcneil Lab., Inc.	Anticonvulsant sulfamate derivatives
GB8712073D0 (en) *	1987-05-21	1987-06-24	Smith Kline French Lab	Medicament
DE19604920A1 (de) *	1996-02-01	1997-08-07	Schering Ag	Neue 2,3-Benzodiazepinderivate, deren Herstellung und Verwendung als Arzneimittel
HUP9701284A3 (en) *	1997-07-24	2005-11-28	Egyt Gyogyszervegyeszeti Gyar	Use of 2,3-benzodiazepine derivatives for producing pharmaceutical compositions for treating and prophylacting illnesses and conditions connected with the endogene opioide system
IL125950A0 (en) *	1997-09-05	1999-04-11	Pfizer Prod Inc	Methods of administering ampa receptor antagonists to treat dyskinesias associated with dopamine agonist therapy
US6583172B1 (en) *	1999-04-08	2003-06-24	Richard P. Shank	Anticonvulsant derivatives useful in treating chronic neurodegenerative disorders
US6420369B1 (en) *	1999-05-24	2002-07-16	Ortho-Mcneil Pharmaceutical, Inc.	Anticonvulsant derivatives useful in treating dementia
FR2824065A1 (fr) *	2001-04-26	2002-10-31	Neuro3D	Composes inhibiteurs des phosphodiesterases des nucleotides cycliques, preparation et utilisations
US6649607B2 (en) *	2001-05-18	2003-11-18	Vela Pharmaceuticals, Inc.	Compositions and methods for treating or preventing convulsions or seizures
RU2195284C1 (ru) *	2001-07-23	2002-12-27	Сибирский государственный медицинский университет	Способ лечения гипертонически-гиперкинетической формы дискинезии желчевыводящих путей у лиц молодого возраста
US6559293B1 (en) *	2002-02-15	2003-05-06	Transform Pharmaceuticals, Inc.	Topiramate sodium trihydrate

2003
- 2003-09-11 JP JP2004535674A patent/JP4630665B2/ja not_active Expired - Fee Related
- 2003-09-11 AT AT03795090T patent/ATE358488T1/de active
- 2003-09-11 CN CN038217309A patent/CN1681512B/zh not_active Expired - Fee Related
- 2003-09-11 ES ES03795090T patent/ES2285245T3/es not_active Expired - Lifetime
- 2003-09-11 DK DK03795090T patent/DK1545546T3/da active
- 2003-09-11 WO PCT/GB2003/003951 patent/WO2004024163A1/en not_active Ceased
- 2003-09-11 PT PT03795090T patent/PT1545546E/pt unknown
- 2003-09-11 DE DE60313005T patent/DE60313005T2/de not_active Expired - Lifetime
- 2003-09-11 CA CA2498735A patent/CA2498735C/en not_active Expired - Fee Related
- 2003-09-11 US US10/527,271 patent/US20050261282A1/en not_active Abandoned
- 2003-09-11 AU AU2003263357A patent/AU2003263357B2/en not_active Ceased
- 2003-09-11 EP EP03795090A patent/EP1545546B1/en not_active Expired - Lifetime
2007
- 2007-07-02 CY CY20071100867T patent/CY1106689T1/el unknown

Also Published As

Publication number	Publication date
WO2004024163A1 (en)	2004-03-25
DE60313005T2 (de)	2007-12-20
DE60313005D1 (de)	2007-05-16
CA2498735C (en)	2011-08-02
EP1545546A1 (en)	2005-06-29
ATE358488T1 (de)	2007-04-15
ES2285245T3 (es)	2007-11-16
PT1545546E (pt)	2007-07-02
US20050261282A1 (en)	2005-11-24
EP1545546B1 (en)	2007-04-04
CN1681512A (zh)	2005-10-12
JP2006502174A (ja)	2006-01-19
CA2498735A1 (en)	2004-03-25
AU2003263357B2 (en)	2009-02-26
AU2003263357A1 (en)	2004-04-30
JP4630665B2 (ja)	2011-02-09
CY1106689T1 (el)	2012-05-23
CN1681512B (zh)	2011-11-09

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