DK1553984T4 - Anvendelse af et farvemiddel til farvning af Membrana Limitans - Google Patents

Anvendelse af et farvemiddel til farvning af Membrana Limitans Download PDF

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Publication number
DK1553984T4
DK1553984T4 DK03757950.5T DK03757950T DK1553984T4 DK 1553984 T4 DK1553984 T4 DK 1553984T4 DK 03757950 T DK03757950 T DK 03757950T DK 1553984 T4 DK1553984 T4 DK 1553984T4
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DK
Denmark
Prior art keywords
dye
use according
blue
buffer
solution
Prior art date
Application number
DK03757950.5T
Other languages
English (en)
Other versions
DK1553984T5 (da
DK1553984T3 (da
Inventor
Hasso Meinert
Bernhard Günther
Wilfried Hiebl
Yong-Keun; Kim
Original Assignee
Fluoron Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32108784&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1553984(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Fluoron Gmbh filed Critical Fluoron Gmbh
Application granted granted Critical
Publication of DK1553984T3 publication Critical patent/DK1553984T3/da
Publication of DK1553984T4 publication Critical patent/DK1553984T4/da
Publication of DK1553984T5 publication Critical patent/DK1553984T5/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0063—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres
    • A61K49/0069—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form
    • A61K49/0071—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form solution, solute
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0023—Di-or triarylmethane dye

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Claims (7)

1. Anvendelse af en vandig fysiologisk kompatibel opløsning, i hvilken et biokompatibelt triphenylmethanfarvestof er opløst, til fremstilling af et farvemiddel til farvning af Membrana limitans interna, der skal fjernes fra øjet ved nethinde- eller glaslegemekirurgi, hvorved farvemidlet foruden døde celler til adskillelse af levende materiale også farver levende celler.
2. Anvendelse ifølge krav 1, hvorved farvestoffet opløses i en neutral eller svag sur eller svag alkalisk buffer.
3. Anvendelse ifølge krav 1, hvorved farvestoffet opløses i en buffer med en pH-værdi på 6,8 til 7,8.
4. Anvendelse ifølge et af kravene 1 til 3, hvorved der anvendes en phosphat-, hydrogencarbonat- eller citrat-buffer.
5. Anvendelse ifølge et af kravene 1 til 4, hvorved koncentrationen af farvestoffet i bufferopløsningen udgør 0,3 til 2,5 g/l, især ca. 1,2 g/liter.
6. Anvendelse ifølge et af kravene 1 til 5, hvorved der som farvestof anvendes patentblå V.
7. Anvendelse ifølge et af kravene 1 til 6, hvorved der som farvestof anvendes brillantblå R.
DK03757950.5T 2002-10-14 2003-10-10 Anvendelse af et farvemiddel til farvning af Membrana Limitans DK1553984T5 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10247781 2002-10-14
DE10255601.6A DE10255601C5 (de) 2002-10-14 2002-11-28 Verwendung eines Triphenylmethanfarbstoffs zur Herstellung eines Färbemittels bei der Netzhaut- und Glaskörperchirurgie
PCT/EP2003/011251 WO2004035091A1 (de) 2002-10-14 2003-10-10 Herstellung eines färbemittels zur anfärbung von zellen im menschlichen oder tierischen körper

Publications (3)

Publication Number Publication Date
DK1553984T3 DK1553984T3 (da) 2009-02-23
DK1553984T4 true DK1553984T4 (da) 2018-08-20
DK1553984T5 DK1553984T5 (da) 2018-09-03

Family

ID=32108784

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03757950.5T DK1553984T5 (da) 2002-10-14 2003-10-10 Anvendelse af et farvemiddel til farvning af Membrana Limitans

Country Status (8)

Country Link
US (1) US20060140863A1 (da)
EP (1) EP1553984B2 (da)
AT (1) ATE412435T1 (da)
DE (4) DE10255601C5 (da)
DK (1) DK1553984T5 (da)
ES (1) ES2319759T5 (da)
PT (1) PT1553984E (da)
WO (1) WO2004035091A1 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE602005013423D1 (de) * 2004-12-06 2009-04-30 Univ Kyushu Nat Univ Corp Farbzusammensetzung zum einfärben einer ophthalmischen membran
EP1733744A1 (en) * 2005-06-17 2006-12-20 Ludwig-Maximilians-Universität München Method, dye and medicament for staining the internal limiting membrane and/or the capsule of an eye
DE102008064065B9 (de) * 2008-12-19 2011-01-05 Fluoron Gmbh Farbstofflösung
GB2493568B (en) * 2011-08-09 2018-08-29 Zeiss Carl Meditec Ag Opthalmologic composition comprising an aqueous solution of at least one viscoelastic polysaccharide
FR2980363B1 (fr) * 2011-09-22 2014-11-28 Arcadophta Composition a toxicite reduite d'au moins un colorant stable et pouvant etre sterilisee
US20130272962A1 (en) * 2012-04-11 2013-10-17 Fluoron Gmbh Staining agent for corneal staining
DE102012110745A1 (de) * 2012-11-09 2014-05-15 Fluoron Gmbh Färbemittel für Hornhautfärbung
DE102012103097A1 (de) 2012-04-11 2013-10-17 Fluoron Gmbh Färbemittel zum Einfärben einer ophthalmischen Membran
EP4204016A1 (en) 2020-08-28 2023-07-05 Vitreq B.V. Ophthalmic dye

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2832491A1 (de) * 1978-07-24 1980-02-07 Merck Patent Gmbh Mittel und verfahren zur anfaerbung von zellabstrichen
DE3014563A1 (de) * 1980-04-16 1981-10-29 Merck Patent Gmbh, 6100 Darmstadt Verfahren zur bestimmung leukaemischer zellen
SE454842B (sv) * 1984-11-01 1988-06-06 Pharmacia Ab Komposition for anvendning vid oftalmologiska applikationer innehallande en vattenlosning av en hogmolekyler polymer och ett lost polymert fergemne
US5122432A (en) * 1990-12-14 1992-06-16 The Mead Corporation Photosensitive microcapsule imaging system having improved gray scale
EP0974367A1 (en) * 1998-05-08 2000-01-26 Gerrit Reinold Jacob Melles The use of a vital dye for facilitating surgical procedures for vitreo-retinal surgery
EP0963759A1 (en) * 1998-05-08 1999-12-15 Gerrit Reinold Jacob Melles The use of a vital dye for facilitating surgical procedures for cataract extraction
JP2004504615A (ja) * 2000-07-20 2004-02-12 ジラ・インク 形成異常の上皮組織を検出するための改良された診断方法
US7014991B2 (en) * 2001-11-16 2006-03-21 Infinite Vision, Llc Use of injectable dyes for staining an anterior lens capsule and vitreo-retinal interface
AU2002366209A1 (en) * 2001-11-20 2003-06-10 Visco Dye Aps Visco dye

Also Published As

Publication number Publication date
DE20321722U1 (de) 2009-05-14
DE10255601B4 (de) 2012-10-25
PT1553984E (pt) 2009-02-05
US20060140863A1 (en) 2006-06-29
EP1553984B9 (de) 2011-09-14
EP1553984A1 (de) 2005-07-20
ES2319759T5 (es) 2018-10-26
DE50310718D1 (de) 2008-12-11
ES2319759T3 (es) 2009-05-12
DK1553984T5 (da) 2018-09-03
WO2004035091A1 (de) 2004-04-29
DE10255601A1 (de) 2004-04-29
EP1553984B2 (de) 2018-05-30
EP1553984B1 (de) 2008-10-29
DE10255601C5 (de) 2017-10-19
DE20321721U1 (de) 2009-05-14
DK1553984T3 (da) 2009-02-23
ATE412435T1 (de) 2008-11-15

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