DK155977C - Fremgangsmaade til fremstilling af en stabil injicerbar vandig oploesning af et tetracyclin-antibiotikum og en jordalkalimetalforbindelse - Google Patents

Fremgangsmaade til fremstilling af en stabil injicerbar vandig oploesning af et tetracyclin-antibiotikum og en jordalkalimetalforbindelse

Info

Publication number: DK155977C
Authority: DK; Denmark
Prior art keywords: earthal; preparing; procedure; aqueous solution; metal compound
Prior art date: 1977-04-27

Application number

DK182578A

Other languages

Danish (da)

English (en)

Other versions

DK182578A (da

DK155977B (da

Inventor

William Wellesley Armstrong

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-04-27

Filing date

1978-04-26

Publication date

1989-10-30

1978-04-26 Application filed by Pfizer filed Critical Pfizer

1978-10-28 Publication of DK182578A publication Critical patent/DK182578A/da

1989-06-12 Publication of DK155977B publication Critical patent/DK155977B/da

1989-10-30 Application granted granted Critical

1989-10-30 Publication of DK155977C publication Critical patent/DK155977C/da

Links

239000007864 aqueous solution Substances 0.000 title 1
230000003115 biocidal effect Effects 0.000 title 1
150000002736 metal compounds Chemical class 0.000 title 1
OFVLGDICTFRJMM-WESIUVDSSA-N tetracycline Chemical compound C1=CC=C2[C@](O)(C)[C@H]3C[C@H]4[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]4(O)C(O)=C3C(=O)C2=C1O OFVLGDICTFRJMM-WESIUVDSSA-N 0.000 title 1
229930101283 tetracycline Natural products 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Oil, Petroleum & Natural Gas (AREA)
Inorganic Chemistry (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Hydrogenated Pyridines (AREA)

DK182578A 1977-04-27 1978-04-26 Fremgangsmaade til fremstilling af en stabil injicerbar vandig oploesning af et tetracyclin-antibiotikum og en jordalkalimetalforbindelse DK155977C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US79162777		1977-04-27
US05/791,627 US4126680A (en)	1977-04-27	1977-04-27	Tetracycline antibiotic compositions

Publications (3)

Publication Number	Publication Date
DK182578A DK182578A (da)	1978-10-28
DK155977B DK155977B (da)	1989-06-12
DK155977C true DK155977C (da)	1989-10-30

Family

ID=25154289

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK182578A DK155977C (da)	1977-04-27	1978-04-26	Fremgangsmaade til fremstilling af en stabil injicerbar vandig oploesning af et tetracyclin-antibiotikum og en jordalkalimetalforbindelse

Country Status (38)

Country	Link
US (1)	US4126680A (el)
JP (1)	JPS53136514A (el)
AR (1)	AR217844A1 (el)
AT (1)	AT360148B (el)
AU (1)	AU503139B1 (el)
BE (1)	BE866419A (el)
BG (1)	BG47943A3 (el)
CA (1)	CA1100875A (el)
CH (1)	CH630260A5 (el)
CS (1)	CS199527B2 (el)
DD (1)	DD135445A5 (el)
DE (1)	DE2817335C3 (el)
DK (1)	DK155977C (el)
EG (1)	EG14348A (el)
ES (1)	ES468749A1 (el)
FI (3)	FI801196A7 (el)
FR (1)	FR2388561A1 (el)
GB (1)	GB1563478A (el)
GR (1)	GR70062B (el)
HU (1)	HU179050B (el)
IE (1)	IE47049B1 (el)
IL (1)	IL54581A0 (el)
IN (1)	IN148197B (el)
IT (1)	IT1094557B (el)
LU (1)	LU79547A1 (el)
MX (1)	MX6087E (el)
NL (1)	NL7804455A (el)
NO (1)	NO148280C (el)
NZ (1)	NZ187046A (el)
OA (1)	OA05949A (el)
PH (1)	PH12962A (el)
PL (1)	PL110459B1 (el)
PT (1)	PT67895B (el)
RO (2)	RO77953A (el)
SE (1)	SE443507B (el)
YU (1)	YU87178A (el)
ZA (1)	ZA782400B (el)
ZM (1)	ZM3878A1 (el)

Families Citing this family (80)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4386083A (en) *	1980-04-10	1983-05-31	Walter Hacke	Injectable oxytetracycline compositions
US4399127A (en) *	1980-04-10	1983-08-16	Diamond Shamrock Corporation	Injectable oxytetracycline compositions
US4806529A (en) *	1982-11-18	1989-02-21	Trustees Of Tufts College, Tufts University	Tetracycline activity enhancement
US5589470A (en) *	1990-02-26	1996-12-31	Trustees Of Tufts College	Reducing tetracycline resistance in living cells
US5064821A (en) *	1982-11-18	1991-11-12	Trustees Of Tufts College	Method and compositions for overcoming tetracycline resistance within living cells
US4769232A (en) *	1984-03-22	1988-09-06	Pfizer Inc.	Parenteral formulations of indolmycin
US6756365B2 (en)	1991-11-06	2004-06-29	Trustees Of Tufts College	Reducing tetracycline resistance in living cells
EP0621033A1 (en) *	1993-04-20	1994-10-26	Nostras S.A.	Antibiotic composition containing oxytetracycline and glycofurol
US8106225B2 (en) *	1999-09-14	2012-01-31	Trustees Of Tufts College	Methods of preparing substituted tetracyclines with transition metal-based chemistries
US6500812B2 (en)	1999-09-14	2002-12-31	Paratek Pharmaceuticals, Inc.	13-substituted methacycline compounds
PT1240133E (pt)	1999-09-14	2006-07-31	Tufts College	Processos para preparar tetraciclinas substituidas com quimicas baseadas em metais de transicao
US6849615B2 (en)	1999-09-14	2005-02-01	Paratek Pharmaceuticals, Inc.	13-substituted methacycline compounds
CA2397863A1 (en)	2000-01-24	2001-07-26	Trustees Of Tufts College	Tetracycline compounds for treatment of cryptosporidium parvum related disorders
WO2001074761A1 (en) *	2000-03-31	2001-10-11	Trustees Of Tufts College	7-and 9-carbamate, urea, thiourea, thiocarbamate, and heteroaryl-amino substituted tetracycline compounds
US6642270B2 (en)	2000-05-15	2003-11-04	Paratek Pharmaceuticals, Inc.	7-substituted fused ring tetracycline compounds
US20040224927A1 (en) *	2000-06-16	2004-11-11	Trustees Of Tufts College	7-N-substituted phenyl tetracycline compounds
WO2001098236A2 (en)	2000-06-16	2001-12-27	Trustees Of Tufts College	7-phenyl-substituted tetracycline compounds
US20020132798A1 (en) *	2000-06-16	2002-09-19	Nelson Mark L.	7-phenyl-substituted tetracycline compounds
US20050143353A1 (en) *	2000-07-07	2005-06-30	Paratek Pharmaceuticals, Inc.	13-Substituted methacycline compounds
IL153672A0 (en) *	2000-07-07	2003-07-06	Tufts College	7-substituted tetracycline compounds
MXPA03000036A (es)	2000-07-07	2003-07-14	Tufts College	Compuestos de metaciclina sustituidos en posicion 13.
US7094806B2 (en) *	2000-07-07	2006-08-22	Trustees Of Tufts College	7, 8 and 9-substituted tetracycline compounds
SI1301467T1 (sl)	2000-07-07	2007-02-28	Tufts College	9-substituirane minociklinske spojine
ATE504562T1 (de)	2000-07-07	2011-04-15	Tufts College	7-, 8- und 9-substitutierte tetracyclinverbindungen
US7553828B2 (en)	2001-03-13	2009-06-30	Paratek Pharmaceuticals, Inc.	9-aminomethyl substituted minocycline compounds
AU2002250331A1 (en)	2001-03-13	2002-09-24	Paratek Pharmaceuticals, Inc.	7-pyrollyl tetracycline compounds and methods of use thereof
EP1368305B1 (en)	2001-03-13	2008-08-13	Paratek Pharmaceuticals, Inc.	7, 9-substituted tetracycline compounds
WO2002072031A2 (en)	2001-03-14	2002-09-19	Paratek Pharmaceuticals, Inc.	Substituted tetracycline compounds as synergistic antifungal agents
CA2457234A1 (en)	2001-03-14	2002-09-19	Mark L. Nelson	Substituted tetracycline compounds as antifungal agents
DE60235083D1 (de)	2001-04-24	2010-03-04	Paratek Pharm Innc	Substituierte tetracyclin-verbindungen zur behandlung von malaria
US8088820B2 (en) *	2001-04-24	2012-01-03	Paratek Pharmaceuticals, Inc.	Substituted tetracycline compounds for the treatment of malaria
ES2551708T3 (es)	2002-01-08	2015-11-23	Paratek Pharmaceuticals, Inc.	Compuestos de 4-desdimetilamino tetraciclina
EP1482926A4 (en)	2002-03-08	2006-04-12	Paratek Pharm Innc	AMINO METHYL SUBSTITUTED TETRACYCLINE COMPOUNDS
WO2003079984A2 (en)	2002-03-21	2003-10-02	Paratek Pharmaceuticals, Inc.	Substituted tetracycline compounds
EA200900540A1 (ru)	2002-07-12	2009-12-30	Пэрэтек Фамэсьютикэлс, Инк.	Замещённые соединения тетрациклина, фармацевтическая композиция и способ лечения чувствительного к тетрациклину состояния у субъекта
AU2003287218C1 (en)	2002-10-24	2010-07-15	Paratek Pharmaceuticals, Inc.	Substituted tetracycline compounds for the treatment of malaria
EP1648859B1 (en)	2003-07-09	2013-02-27	Paratek Pharmaceuticals, Inc.	Substituted tetracycline compounds
JP4738333B2 (ja)	2003-07-09	2011-08-03	パラテックファーマシューティカルズインコーポレイテッド	９−アミノメチルテトラサイクリン化合物のプロドラッグ
NZ544826A (en) *	2003-07-25	2008-07-31	Warner Chilcott Co Inc	A doxycycline metal complex in a solid dosage form
US7786099B2 (en) *	2004-01-15	2010-08-31	Paratek Pharmaceuticals, Inc.	Aromatic a-ring derivatives of tetracycline compounds
TWI261038B (en) *	2004-08-11	2006-09-01	Bo-Cheng Chen	Bicycle gear-shifting handgrip
WO2006047671A2 (en) *	2004-10-25	2006-05-04	Paratek Pharmaceuticals, Inc.	4-aminotetracyclines and methods of use thereof
EP2269991A3 (en)	2004-10-25	2011-09-21	Paratek Pharmaceuticals, Inc.	Substituted tetracycline compounds
WO2006084265A1 (en)	2005-02-04	2006-08-10	Paratek Pharmaceuticals, Inc.	11a, 12-DERIVATIVES OF TETRACYCLINE COMPOUNDS
US7919483B2 (en) *	2005-06-24	2011-04-05	Medicis Pharmaceutical Corporation	Method for the treatment of acne
US8722650B1 (en)	2005-06-24	2014-05-13	Medicis Pharmaceutical Corporation	Extended-release minocycline dosage forms
US7541347B2 (en) *	2007-04-02	2009-06-02	Medicis Pharmaceutical Coropration	Minocycline oral dosage forms for the treatment of acne
US20080241235A1 (en) *	2007-04-02	2008-10-02	Medicis Pharmaceutical Corporation	Minocycline oral dosage forms for the treatment of acne
US7544373B2 (en) *	2007-04-02	2009-06-09	Medicis Pharmaceutical Corporation	Minocycline oral dosage forms for the treatment of acne
US8252776B2 (en)	2007-04-02	2012-08-28	Medicis Pharmaceutical Corporation	Minocycline oral dosage forms for the treatment of acne
US20080242642A1 (en) *	2007-04-02	2008-10-02	Medicis Pharmaceutical Corporation	Minocycline oral dosage forms for the treatment of acne
US9192615B2 (en)	2008-08-06	2015-11-24	Medicis Pharmaceutical Corporation	Method for the treatment of acne and certain dosage forms thereof
US9078811B2 (en) *	2006-01-24	2015-07-14	Paratek Pharmaceuticals, Inc.	Methods of increasing oral bioavailability of tetracyclines
CN101489987A (zh) *	2006-04-17	2009-07-22	特瓦制药工业有限公司	四环素衍生物的分离
US8198470B2 (en) *	2006-04-24	2012-06-12	Teva Pharmaceutical Industries Ltd.	Crystalline form II of tigecycline and processes for preparation thereof
DK2016045T3 (en) *	2006-04-24	2015-02-02	Teva Pharma	TIGECYCLIN CRYSTAL FORM AND PROCEDURES FOR PREPARING IT
CA2652347A1 (en) *	2006-05-15	2007-11-22	Paratek Pharmaceuticals, Inc.	Methods of regulating expression of genes or of gene products using substituted tetracycline compounds
ES2315123B1 (es) *	2006-09-25	2009-12-30	Divasa-Farmavic, S.A.	Composiciones farmaceuticas estables de tetraciclinas en solucion, procedimiento para su obtencion y sus usos.
US8440646B1 (en)	2006-10-11	2013-05-14	Paratek Pharmaceuticals, Inc.	Substituted tetracycline compounds for treatment of Bacillus anthracis infections
EP2450347B1 (en)	2006-12-21	2015-06-24	Paratek Pharmaceuticals, Inc.	Tetracycline derivatives for the treatment of bacterial, viral and parasitic infections
PT2120963T (pt)	2006-12-21	2018-12-17	Paratek Pharm Innc	Compostos tetraciclina substituídos para tratamento de distúrbios inflamatórios da pele
AU2012230089B2 (en) *	2007-03-23	2013-11-21	Molecular Research Center, Inc.	Anti-inflammatory compositions comprising tetracyclines and use thereof in therapy
KR20090122994A (ko) *	2007-03-23	2009-12-01	몰레큘러 리서치 센터, 인크.	테트라사이클린류를 함유하는 항염증성 조성물 및 이의 치료 용도
US20080241197A1 (en) *	2007-04-02	2008-10-02	Medicis Pharmaceutical Corporation	Minocycline dosage forms for the treatment of acne
WO2008127722A1 (en) *	2007-04-12	2008-10-23	Paratek Pharmaceuticals, Inc.	Methods for treating spinal muscular atrophy using tetracycline compounds
JP2010525069A (ja) *	2007-04-27	2010-07-22	パラテックファーマシューティカルズインコーポレイテッド	アミノアルキルテトラサイクリン化合物の合成方法および精製方法
BRPI0813990A2 (pt)	2007-07-06	2011-09-13	Paratek Pharmaceuticals, Inc.	métodos para sintetizar compostos de minociclina substituìda
US20090253660A1 (en)	2008-03-05	2009-10-08	Paratek Pharmaceuticals, Inc.	Minocycline Compounds and Methods of Use Thereof
PT2271348T (pt)	2008-03-28	2018-04-16	Paratek Pharm Innc	Formulação de comprimido oral de composto de tetraciclina
JP2011517697A (ja) *	2008-04-14	2011-06-16	パラテックファーマシューティカルズインコーポレイテッド	置換テトラサイクリン化合物
TWI680117B (zh)	2008-05-19	2019-12-21	派洛泰克藥物股份有限公司	四環素化合物之甲苯磺酸鹽及同素異形體
US20100190755A1 (en) *	2008-09-19	2010-07-29	Paul Abato	Tetracycline compounds for the treatment of rheumatoid arthritis and related methods of treatment
EP2416799B1 (en)	2009-04-10	2017-11-01	Tufts Medical Center, Inc.	Par-1 activation by metalloproteinase-1 (mmp-1)
US9255068B2 (en)	2011-05-12	2016-02-09	Warner Chilcott Company, Llc	Crystalline salts of (4S,4AS,5AR,12AS)-4-dimethylamino-3,10,12,12A-tetrahydroxy-7-[methoxy(methyl)amino)-methyl] acid amide and methods of using the same
US9561241B1 (en)	2011-06-28	2017-02-07	Medicis Pharmaceutical Corporation	Gastroretentive dosage forms for minocycline
EP2805732B1 (en) *	2013-05-20	2016-09-28	Fundación Comunidad Valenciana Centro de Investigación Principe Felipe	Polymer-drug conjugates for the treatment of amyloidosis
AU2016235237B2 (en)	2015-03-23	2021-03-11	BioPharmX, Inc.	Pharmaceutical tetracycline composition for dermatological use
SG10201913599RA (en)	2016-11-01	2020-02-27	Paratek Pharm Innc	9-aminomethyl minocycline compounds and use thereof in treating community-acquired bacterial pneumonia (cabp)
AU2018303807B2 (en)	2017-07-21	2023-08-24	Almirall, Llc	Treatment of non-inflammatory lesions
CN113655052B (zh) *	2021-08-03	2023-12-12	哈尔滨工程大学	基于高活性MgO对四环素类抗生素可视化检测的方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US1913323A (en) *	1931-02-28	1933-06-06	Hoffmann La Roche	Stable concentrated solution for therapeutic purposes
DE647766C (de) *	1931-03-01	1937-07-12	Hoffmanni La Roche & Co Akt Ge	Verfahren zur Darstellung haltbarer, konzentrierter, waessriger Loesungen der Cinchonaalkaloide
GB381012A (en) *	1931-12-04	1932-09-29	Andrew Home Morton	Process for the manufacture of stable concentrated solutions for therapeutic use
DE662812C (de) *	1931-12-08	1938-07-22	Hoffmanni La Roche & Co Akt Ge	Verfahren zur Herstellung haltbarer, waessriger Arzneimittelloesungen
DE673500C (de) *	1933-01-15	1939-03-23	Hoffmann La Roche & Co Akt Ges	Verfahren zur Herstellung von haltbaren Loesungen schwer loeslicher Arzneimittel
GB1019164A (en) *	1963-01-30	1966-02-02	Chugai Pharmaceutical Co Ltd	Hemostatic preparation for injection and process for the production thereof
DK129969B (da) *	1973-01-11	1974-12-09	Rosco Ak	Fremgangsmåde til fremstilling af en klar, stabil, i det væsentlige vandig opløsning af oxytetracyclin.
GB1508601A (en) *	1974-01-19	1978-04-26	Norbrook Labor Ltd	Oxytetracycline solution
US4018889A (en) *	1976-01-02	1977-04-19	Pfizer Inc.	Oxytetracycline compositions

1977
- 1977-04-27 US US05/791,627 patent/US4126680A/en not_active Expired - Lifetime
1978
- 1978-02-16 SE SE7801816A patent/SE443507B/sv not_active IP Right Cessation
- 1978-03-30 IN IN234/DEL/78A patent/IN148197B/en unknown
- 1978-04-03 PH PH20970A patent/PH12962A/en unknown
- 1978-04-07 DD DD78204656A patent/DD135445A5/xx unknown
- 1978-04-07 MX MX787004U patent/MX6087E/es unknown
- 1978-04-08 RO RO78102215A patent/RO77953A/ro unknown
- 1978-04-08 RO RO7893756A patent/RO75099A/ro unknown
- 1978-04-11 ZM ZM38/78A patent/ZM3878A1/xx unknown
- 1978-04-12 PT PT67895A patent/PT67895B/pt unknown
- 1978-04-12 YU YU00871/78A patent/YU87178A/xx unknown
- 1978-04-13 ES ES468749A patent/ES468749A1/es not_active Expired
- 1978-04-13 PL PL1978206050A patent/PL110459B1/pl unknown
- 1978-04-13 HU HU78PI616A patent/HU179050B/hu not_active IP Right Cessation
- 1978-04-14 BG BG039431A patent/BG47943A3/xx unknown
- 1978-04-14 CS CS782444A patent/CS199527B2/cs unknown
- 1978-04-14 AR AR271783A patent/AR217844A1/es active
- 1978-04-15 EG EG256/78A patent/EG14348A/xx active
- 1978-04-20 DE DE2817335A patent/DE2817335C3/de not_active Expired
- 1978-04-21 NZ NZ187046A patent/NZ187046A/xx unknown
- 1978-04-24 JP JP4865978A patent/JPS53136514A/ja active Granted
- 1978-04-24 AU AU35378/78A patent/AU503139B1/en not_active Expired
- 1978-04-25 GB GB16167/78A patent/GB1563478A/en not_active Expired
- 1978-04-25 CA CA301,904A patent/CA1100875A/en not_active Expired
- 1978-04-26 BE BE187143A patent/BE866419A/xx not_active IP Right Cessation
- 1978-04-26 AT AT300478A patent/AT360148B/de not_active IP Right Cessation
- 1978-04-26 IE IE828/78A patent/IE47049B1/en not_active IP Right Cessation
- 1978-04-26 FI FI801196A patent/FI801196A7/fi not_active Application Discontinuation
- 1978-04-26 FI FI801197A patent/FI801197A7/fi not_active Application Discontinuation
- 1978-04-26 FI FI781300A patent/FI781300A7/fi not_active Application Discontinuation
- 1978-04-26 IL IL54581A patent/IL54581A0/xx not_active IP Right Cessation
- 1978-04-26 FR FR7812299A patent/FR2388561A1/fr active Granted
- 1978-04-26 OA OA56480A patent/OA05949A/xx unknown
- 1978-04-26 IT IT22720/78A patent/IT1094557B/it active
- 1978-04-26 GR GR56113A patent/GR70062B/el unknown
- 1978-04-26 DK DK182578A patent/DK155977C/da active
- 1978-04-26 NO NO781457A patent/NO148280C/no unknown
- 1978-04-26 NL NL7804455A patent/NL7804455A/xx not_active Application Discontinuation
- 1978-04-26 ZA ZA00782400A patent/ZA782400B/xx unknown
- 1978-04-26 CH CH453678A patent/CH630260A5/fr not_active IP Right Cessation
- 1978-04-27 LU LU79547A patent/LU79547A1/xx unknown

Also Published As

Publication number	Publication date
FR2388561B1 (el)	1980-07-18
IE47049B1 (en)	1983-12-14
BG47943A3 (bg)	1990-10-15
AR217844A1 (es)	1980-04-30
DK182578A (da)	1978-10-28
RO75099A (ro)	1980-12-30
LU79547A1 (fr)	1979-11-07
PT67895A (en)	1978-05-01
IT1094557B (it)	1985-08-02
YU87178A (en)	1984-04-30
SE443507B (sv)	1986-03-03
DD135445A5 (de)	1979-05-09
PH12962A (en)	1979-10-19
DE2817335B2 (de)	1981-06-11
JPS5632290B2 (el)	1981-07-27
NL7804455A (nl)	1978-10-31
CH630260A5 (fr)	1982-06-15
HU179050B (en)	1982-08-28
OA05949A (fr)	1981-06-30
NO781457L (no)	1978-10-30
AU503139B1 (en)	1979-08-23
PL206050A1 (pl)	1979-03-26
SE7801816L (sv)	1978-10-28
US4126680A (en)	1978-11-21
RO77953A (ro)	1981-12-25
NZ187046A (en)	1980-03-05
MX6087E (es)	1984-11-08
CA1100875A (en)	1981-05-12
IT7822720A0 (it)	1978-04-26
ZA782400B (en)	1979-04-25
BE866419A (fr)	1978-10-26
FI801197A7 (fi)	1981-01-01
NO148280B (no)	1983-06-06
JPS53136514A (en)	1978-11-29
AT360148B (de)	1980-12-29
IL54581A0 (en)	1978-07-31
FR2388561A1 (fr)	1978-11-24
ES468749A1 (es)	1979-01-01
CS199527B2 (en)	1980-07-31
DE2817335C3 (de)	1982-04-22
FI781300A7 (fi)	1978-10-28
DE2817335A1 (de)	1978-11-16
FI801196A7 (fi)	1981-01-01
GB1563478A (en)	1980-03-26
GR70062B (el)	1982-07-26
DK155977B (da)	1989-06-12
ZM3878A1 (en)	1978-11-21
ATA300478A (de)	1980-05-15
PT67895B (en)	1979-11-14
NO148280C (no)	1983-09-21
IE780828L (en)	1978-10-27
PL110459B1 (en)	1980-07-31
IN148197B (el)	1980-11-29
EG14348A (en)	1984-09-30

Publication	Publication Date	Title
DK145753C (da)	1983-08-08	Fremgangsmaade til fremstilling af en stabil vandig oploesning af et tetracyclin-antibioticum og en jordalkalimetalforbindelse
RO75099A (ro)	1980-12-30	Procedeu de preparare a unor compozitii stabile de antibiotice continind tetraciclina
DK113878A (da)	1978-09-15	Substituerede pyridylmethylestere af cyklopropancarboxylsyrer der er anvendelige som insekticider
IT1101202B (it)	1985-09-28	Siringa
DK491877A (da)	1978-12-17	Sproejte
FI783844A7 (fi)	1979-06-30	Ftalazin-4-ylaettiksyraderivat
SE7808960L (sv)	1979-02-27	Spruta
IT7849175A0 (it)	1978-05-03	Derivati n-alchil-n-acilici della tienamicina
PL212223A1 (pl)	1979-08-27	Sposob wytwarzania pochodnych guanidyny
PL206450A1 (pl)	1979-03-26	Sposob wytwarzania pochodnych mocznika
PL209363A1 (pl)	1979-06-04	Srodek owadobojczy i roztoczobojczy oraz sposob wytwarzania podstawionych fluorem pochodnych fenoksybenzyloksykarbonylowych
DK96380A (da)	1980-10-17	Fremgangsmaade til fremstilling af stabile injicerbare oploesninger af et oxytetracyclinchelatt
IT1094656B (it)	1985-08-02	Circuito amplificatore di impulsi
AU3728478A (en)	1980-01-03	Derivatives of amidinopenicillanic acid
DK302578A (da)	1979-01-06	Reduktion af phosphinoxider
SE7803404L (sv)	1978-10-20	Losning och substans for dess framstellning
GB2002764B (en)	1982-08-04	Derivatives of n-substituted-2-aminobenzoic acid
IT1093710B (it)	1985-07-26	Derivati della chinazolina
IT1097159B (it)	1985-08-26	Analoghi di prostaglandige
DK28078A (da)	1978-07-21	Fremgangsmaade til fremstilling af et tetraalkylthiuramdisulfid
IT1096628B (it)	1985-08-26	Derivati di 15-sostituita-w-pentanorprostaglandina
GB2003149B (en)	1982-03-03	Derivatives of oxanilic acid
DK196178A (da)	1978-11-07	Fremgangsmaade til fremstilling af pregn-4-enderivater
RO78489A (ro)	1982-02-26	Procedeu pentru prepararea tiadiazolil-benzamidelor
IT1110865B (it)	1986-01-06	Derivati della penicillina