DK1565746T3 - Fremgangsmåde og prober til detektion af et tumor-specifikt fusionsprotein - Google Patents

Fremgangsmåde og prober til detektion af et tumor-specifikt fusionsprotein

Info

Publication number
DK1565746T3
DK1565746T3 DK03772958.9T DK03772958T DK1565746T3 DK 1565746 T3 DK1565746 T3 DK 1565746T3 DK 03772958 T DK03772958 T DK 03772958T DK 1565746 T3 DK1565746 T3 DK 1565746T3
Authority
DK
Denmark
Prior art keywords
probes
fusion protein
detecting
tumor
methods
Prior art date
Application number
DK03772958.9T
Other languages
English (en)
Inventor
Dongen Jacobus Johannes Maria Van
Original Assignee
Univ Erasmus
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Erasmus filed Critical Univ Erasmus
Application granted granted Critical
Publication of DK1565746T3 publication Critical patent/DK1565746T3/da

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y10/00—Nanotechnology for information processing, storage or transmission, e.g. quantum computing or single electron logic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y20/00—Nanooptics, e.g. quantum optics or photonic crystals
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57505—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the blood, e.g. leukaemia
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • G01N33/57595—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving intracellular compounds
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/108331—Preservative, buffer, anticoagulant or diluent

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biophysics (AREA)
  • Theoretical Computer Science (AREA)
  • Mathematical Physics (AREA)
  • Optics & Photonics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
DK03772958.9T 2002-11-07 2003-11-06 Fremgangsmåde og prober til detektion af et tumor-specifikt fusionsprotein DK1565746T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02079666 2002-11-07
PCT/NL2003/000776 WO2004042398A1 (en) 2002-11-07 2003-11-06 Method and probes for the detection of a tunor specific fusion protein

Publications (1)

Publication Number Publication Date
DK1565746T3 true DK1565746T3 (da) 2011-01-10

Family

ID=32309413

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03772958.9T DK1565746T3 (da) 2002-11-07 2003-11-06 Fremgangsmåde og prober til detektion af et tumor-specifikt fusionsprotein

Country Status (13)

Country Link
US (2) US7575874B2 (da)
EP (1) EP1565746B1 (da)
JP (1) JP4594733B2 (da)
CN (1) CN1735805A (da)
AT (1) ATE480774T1 (da)
AU (1) AU2003279618B2 (da)
CA (1) CA2505509C (da)
DE (1) DE60334144D1 (da)
DK (1) DK1565746T3 (da)
ES (1) ES2352050T3 (da)
NZ (1) NZ540218A (da)
PT (1) PT1565746E (da)
WO (1) WO2004042398A1 (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1565746B1 (en) 2002-11-07 2010-09-08 Erasmus Universiteit Rotterdam Method and probes for the detection of a tumor specific fusion protein
JP2007040834A (ja) * 2005-08-03 2007-02-15 Japan Science & Technology Agency 免疫測定用試薬
DE212006000071U1 (de) * 2005-11-18 2008-07-24 Board of Regents, The University of Texas System, Austin Quantifizierung von Fusionsproteinen und ihrer Aktivität in Folge chromosomaler Translokation
US8134743B2 (en) * 2007-07-18 2012-03-13 Xerox Corporation Methods and systems for routing and processing jobs in a production environment
US20110229415A1 (en) * 2007-08-06 2011-09-22 Sylvia Daunert Semi-synthetic antibodies as recognition elements
CN101868728A (zh) * 2007-11-21 2010-10-20 鹿特丹伊拉斯姆斯大学医疗中心 改进的fret探针及其应用
WO2012057689A1 (en) * 2010-10-29 2012-05-03 Ge Healthcare Bio-Sciences Ab Proximity ligation technology for western blot applications
US9823246B2 (en) 2011-12-28 2017-11-21 The Board Of Trustees Of The Leland Stanford Junior University Fluorescence enhancing plasmonic nanoscopic gold films and assays based thereon
CN104155452A (zh) * 2013-05-15 2014-11-19 复旦大学 一种检测细胞内蛋白质降解的方法
ES2732476T3 (es) * 2014-10-30 2019-11-22 Univ Erasmus Med Ct Rotterdam Reactivos, métodos y kits para el diagnóstico de inmunodeficiencias primarias
US20160146799A1 (en) * 2014-11-05 2016-05-26 Nirmidas Biotech, Inc. Metal composites for enhanced imaging
CN106124500B (zh) * 2016-08-29 2019-09-03 华北理工大学 一种用菁染料可视化识别转铁蛋白的方法
MA47747A (fr) * 2017-03-09 2020-01-15 Shriners Hospitals Children Tests de mesure du collagène de type x et méthodes d'utilisation de ceux-ci
CN110407918B (zh) * 2019-07-22 2021-06-18 上海交通大学医学院附属瑞金医院 一种温敏靶向荧光探针及其制备方法和应用
WO2021041874A1 (en) 2019-08-29 2021-03-04 Martin David C Biofunctional thiophene monomers

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5091206A (en) * 1987-10-26 1992-02-25 Baxter Diagnostics Inc. Process for producing magnetically responsive polymer particles and application thereof
WO1992021032A1 (en) 1991-05-24 1992-11-26 The Regents Of The University Of California Methods for the detection of bcr-abl and abnormal abl proteins in leukemia patients
US5514340A (en) * 1994-01-24 1996-05-07 Magnetix Biotechnology, Inc. Device for separating magnetically labelled cells
US6107457A (en) * 1995-02-16 2000-08-22 Board Of Regents, The University Of Texas System Bcr-Abl directed compositions and uses for inhibiting Philadelphia chromosome stimulated cell growth
US6159748A (en) * 1995-03-13 2000-12-12 Affinitech, Ltd Evaluation of autoimmune diseases using a multiple parameter latex bead suspension and flow cytometry
US6686165B2 (en) 1997-05-20 2004-02-03 Erasmus Universiteit Rotterdam Recognition of tumor-specific gene products in cancer
EP0983510B1 (en) 1997-05-20 2004-03-03 Erasmus Universiteit Rotterdam Recognition of tumour-specific gene products in cancer
JP3513068B2 (ja) * 1999-05-12 2004-03-31 浜松ホトニクス株式会社 生細胞の細胞質内標的核酸を検出する方法
AU781992B2 (en) * 2000-04-04 2005-06-23 Medical Research Council Methods involving induced dimerisation by cellular components
WO2002088733A1 (fr) * 2001-04-23 2002-11-07 Eiken Kagaku Kabushiki Kaisha Methode d'analyse faisant intervenir une interaction intermoleculaire par rapporteur (marqueur)
CA2411392C (en) * 2001-11-07 2012-10-16 Stemcell Technologies Inc. Tetrameric antibody complexes for blocking non-specific binding of antigens
EP1565746B1 (en) 2002-11-07 2010-09-08 Erasmus Universiteit Rotterdam Method and probes for the detection of a tumor specific fusion protein
EP1507147A1 (en) 2003-08-12 2005-02-16 Erasmus University Medical Center Rotterdam Method for detecting low levels of a fusion protein

Also Published As

Publication number Publication date
ATE480774T1 (de) 2010-09-15
WO2004042398A1 (en) 2004-05-21
CA2505509C (en) 2013-08-20
PT1565746E (pt) 2010-12-07
EP1565746B1 (en) 2010-09-08
NZ540218A (en) 2009-03-31
US7575874B2 (en) 2009-08-18
ES2352050T3 (es) 2011-03-18
EP1565746A1 (en) 2005-08-24
US20050260684A1 (en) 2005-11-24
DE60334144D1 (de) 2010-10-21
CA2505509A1 (en) 2004-05-21
AU2003279618A1 (en) 2004-06-07
CN1735805A (zh) 2006-02-15
US20090305305A1 (en) 2009-12-10
US7993850B2 (en) 2011-08-09
JP4594733B2 (ja) 2010-12-08
AU2003279618B2 (en) 2009-07-16
JP2006505774A (ja) 2006-02-16
ES2352050T5 (es) 2011-02-15

Similar Documents

Publication Publication Date Title
DK1565746T3 (da) Fremgangsmåde og prober til detektion af et tumor-specifikt fusionsprotein
ATE511649T1 (de) Verbesserte fret-sonden und ihre verwendung
DK1137943T3 (da) Fremgangsmåde til påvisning af cancer og reagenser
DK0815257T3 (da) Fremgangsmåde til karakterisering af biologisk aktive stoffer
DK0932830T3 (da) Fluorescens-energioverførselsligandvekselvirkningsanalyse på en lipidfilm
AU2849300A (en) Methods and assay kits for detecting mononuclear cell phenotype
ATE381019T1 (de) Rückwärtsbestimmung von abo-blutgruppen
GB2430740A (en) System and method for tracking and quatitating chemical entites
ATE472107T1 (de) Ic-testverfahren und vorrichtungen
NO20010362L (no) Nukleinsyrer kodende for proteiner som er involvert i sensorisk transduksjon
ATE283486T1 (de) Differenz-nachweismethoden unter verwendung einer vielzahl von abgestimmten farbstoffen
WO2003006684A3 (de) Vorrichtung und verfahren zum nachweis der photosynthese-hemmung
ES2170152T3 (es) Virus de la hepatitis g y clon molecular del mismo.
GB2377272A (en) Method and apparatus for DNA sequencing
ATE326537T1 (de) Schnell erzeugung von stabilen säugertier- zellinien mit gewinnung eines hohen gehalts von recombinanten proteine
DK1179183T3 (da) Fremgangsmåde til identifikation af præneoplastiske og/eller neoplastiske tilstande hos pattedyr
DE69808930D1 (de) Leberfunktionstest
DK0960336T3 (da) Peptidreagens til påvisning af humant cytomelagovirus (CMV)
WO2003033650A3 (en) Recombinant renilla reniformis system for bioluminescence resonance energy transfer
WO2007068313A3 (en) Targeting and tracing of antigens in living cells
DK1386160T3 (da) Fremgangsmåde til påvisning af blodcelle-antigener og antistoffer rettet mod disse
EP1452595A4 (en) ES CELLS WITH INCREASED RNAI EFFECT
DE60216721D1 (de) Verfahren zum Nachweis von Protein-Proteininteraktionen in Membranen
WO2024138141A3 (en) Antibodies against metapneumovirus fusion (f) protein and uses thereof
WO2006024875A3 (en) Method for determinig protein solubility