DK156644C - 3-acetoxy-24,24-difluor-25-hydroxy-cholestan-5,7-dien - Google Patents

3-acetoxy-24,24-difluor-25-hydroxy-cholestan-5,7-dien

Info

Publication number: DK156644C
Authority: DK; Denmark
Prior art keywords: cholestane; acetoxy; difluoro; diene; hydroxy
Prior art date: 1979-03-05

Application number

DK446482A

Other languages

English (en)

Other versions

DK156644B (da

DK446482A (da

Inventor

Hector F Deluca

Nobuo Ikekawa

Yoko Tanaka

Yoshiro Kobayashi

Original Assignee

Wisconsin Alumni Res Found

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-03-05

Filing date

1982-10-08

Publication date

1990-02-12

1982-10-08 Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found

1982-10-08 Publication of DK446482A publication Critical patent/DK446482A/da

1989-09-18 Publication of DK156644B publication Critical patent/DK156644B/da

1990-02-12 Application granted granted Critical

1990-02-12 Publication of DK156644C publication Critical patent/DK156644C/da

Links

QFJZFUWPKOFYCY-HWHNCCJPSA-N [(9S,10R,13R,14R,17R)-17-[(2R)-5,5-difluoro-6-hydroxy-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,9,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate Chemical compound C1C(OC(C)=O)CC[C@]2(C)[C@@H](CC[C@@]3([C@@H]([C@@H](CCC(F)(F)C(C)(C)O)C)CC[C@H]33)C)C3=CC=C21 QFJZFUWPKOFYCY-HWHNCCJPSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicinal Chemistry (AREA)
Hematology (AREA)
Obesity (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Diabetes (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Rheumatology (AREA)
Endocrinology (AREA)
Nutrition Science (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Steroid Compounds (AREA)

DK446482A 1979-03-05 1982-10-08 3-acetoxy-24,24-difluor-25-hydroxy-cholestan-5,7-dien DK156644C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US1716879		1979-03-05
US06/017,168 US4196133A (en)	1979-03-05	1979-03-05	24,24-Difluoro-25-hydroxycholecalciferol

Publications (3)

Publication Number	Publication Date
DK446482A DK446482A (da)	1982-10-08
DK156644B DK156644B (da)	1989-09-18
DK156644C true DK156644C (da)	1990-02-12

Family

ID=21781101

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
DK467780A DK156635C (da)	1979-03-05	1980-11-04	Analogifremgangsmaade til fremstilling af 24,24-difluor-25-hydroxycholecalciferol
DK446482A DK156644C (da)	1979-03-05	1982-10-08	3-acetoxy-24,24-difluor-25-hydroxy-cholestan-5,7-dien
DK425183A DK156726C (da)	1979-03-05	1983-09-19	3-hydroxy-24,24-difluor-25-hydroxy-cholestan-5,7-dien

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
DK467780A DK156635C (da)	1979-03-05	1980-11-04	Analogifremgangsmaade til fremstilling af 24,24-difluor-25-hydroxycholecalciferol

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
DK425183A DK156726C (da)	1979-03-05	1983-09-19	3-hydroxy-24,24-difluor-25-hydroxy-cholestan-5,7-dien

Country Status (16)

Country	Link
US (1)	US4196133A (da)
JP (2)	JPS6310946B2 (da)
AU (1)	AU532388B2 (da)
BE (1)	BE882036A (da)
CA (1)	CA1157049A (da)
CH (2)	CH654015A5 (da)
DK (3)	DK156635C (da)
FR (2)	FR2450814B1 (da)
GB (1)	GB2044770B (da)
IE (1)	IE49532B1 (da)
IL (1)	IL58525A (da)
IT (1)	IT1151077B (da)
NL (1)	NL7920160A (da)
NZ (1)	NZ191899A (da)
SE (1)	SE8007427L (da)
WO (1)	WO1980001915A1 (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4284577A (en) *	1979-02-16	1981-08-18	Sachiko Yamada	Novel vitamin D3 derivative and process for preparing the same
US4248791A (en) *	1980-02-04	1981-02-03	Wisconsin Alumni Research Foundation	25-Hydroxy-26,26,26,27,27,27-hexafluorocholecalciferol
US4254045A (en) *	1980-04-21	1981-03-03	Wisconsin Alumni Research Foundation	1α-Hydroxy-2β-fluorocholecalciferol
US4307025A (en) *	1981-02-17	1981-12-22	Wisconsin Alumni Research Foundation	1α, 25-dihydroxy-2β-fluorovitamin D3
US4428946A (en) *	1982-07-26	1984-01-31	Wisconsin Alumni Research Foundation	Method of preventing milk fever in dairy cattle
US4500460A (en) *	1983-08-18	1985-02-19	Wisconsin Alumni Research Foundation	23,23-Difluoro-25-hydroxy-vitamin D3 and process for preparing same
FR2550789B1 (fr) *	1983-08-18	1987-12-04	Wisconsin Alumni Res Found	23,23-difluoro-25-hydroxy- et 1a,25-dihydroxy-vitamine d3
US4564474A (en) *	1983-08-18	1986-01-14	Wisconsin Alumni Research Foundation	23,23-Difluoro-25-hydroxy-vitamin D3 and process for preparing same
ATE45347T1 (de) *	1985-05-30	1989-08-15	Taisho Pharmaceutical Co Ltd	Vitamin d3-derivate.
KR20010043558A (ko) *	1998-05-13	2001-05-25	한센 핀 베네드, 안네 제헤르, 웨이콥 마리안느	감수분열 조절 화합물
JP3485097B2 (ja)	2001-03-13	2004-01-13	日本電気株式会社	移動無線通信における適応再送要求制御方式、及び適応再送要求制御装置

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3993675A (en) *	1975-02-24	1976-11-23	Hoffmann-La Roche Inc.	Process for the preparation of 1α,25-dihydroxycholecalciferol
US4069321A (en) *	1975-10-14	1978-01-17	Merck & Co., Inc.	Blocked cholecalciferol and dihydrotachysterol 3 derivatives
US4028349A (en) *	1976-03-08	1977-06-07	Hoffmann-La Roche Inc.	Syntheses of 24R,25- and 24S,25-dihydroxycholesterol 24,25-ketals and alkanoyl derivatives thereof
JPS595432B2 (ja) *	1976-11-09	1984-02-04	凸版印刷株式会社	容器の製造方法
US4188345A (en) *	1978-07-26	1980-02-12	Wisconsin Alumni Research Foundation	Fluorovitamin D compounds and processes for their preparation
US4284577A (en) *	1979-02-16	1981-08-18	Sachiko Yamada	Novel vitamin D3 derivative and process for preparing the same

1979
- 1979-03-05 US US06/017,168 patent/US4196133A/en not_active Expired - Lifetime
- 1979-10-15 JP JP55500008A patent/JPS6310946B2/ja not_active Expired
- 1979-10-15 WO PCT/US1979/000898 patent/WO1980001915A1/en not_active Ceased
- 1979-10-15 CH CH1133/85A patent/CH654015A5/de not_active IP Right Cessation
- 1979-10-15 CH CH8306/80A patent/CH653018A5/de not_active IP Right Cessation
- 1979-10-15 NL NL7920160A patent/NL7920160A/xx unknown
- 1979-10-22 IL IL58525A patent/IL58525A/xx unknown
- 1979-10-23 NZ NZ191899A patent/NZ191899A/en unknown
1980
- 1980-02-22 AU AU55809/80A patent/AU532388B2/en not_active Ceased
- 1980-02-28 CA CA000346646A patent/CA1157049A/en not_active Expired
- 1980-03-03 GB GB8007118A patent/GB2044770B/en not_active Expired
- 1980-03-03 BE BE0/199639A patent/BE882036A/fr not_active IP Right Cessation
- 1980-03-03 IT IT20326/80A patent/IT1151077B/it active
- 1980-03-03 IE IE420/80A patent/IE49532B1/en unknown
- 1980-03-04 FR FR8004852A patent/FR2450814B1/fr not_active Expired
- 1980-09-02 FR FR8018944A patent/FR2455609A1/fr active Granted
- 1980-10-22 SE SE8007427A patent/SE8007427L/xx unknown
- 1980-11-04 DK DK467780A patent/DK156635C/da not_active IP Right Cessation
1982
- 1982-10-08 DK DK446482A patent/DK156644C/da not_active IP Right Cessation
1983
- 1983-09-19 DK DK425183A patent/DK156726C/da not_active IP Right Cessation
1987
- 1987-09-16 JP JP62229954A patent/JPS63183559A/ja active Granted

Also Published As

Publication number	Publication date
DK425183D0 (da)	1983-09-19
GB2044770B (en)	1983-05-11
AU5580980A (en)	1980-09-11
DK156726C (da)	1990-03-05
FR2450814B1 (fr)	1986-04-11
DK156644B (da)	1989-09-18
IT8020326A0 (it)	1980-03-03
IL58525A0 (en)	1980-01-31
IL58525A (en)	1983-02-23
NL7920160A (nl)	1980-12-31
AU532388B2 (en)	1983-09-29
NZ191899A (en)	1984-11-09
IE800420L (en)	1980-09-05
DK425183A (da)	1983-09-19
CA1157049A (en)	1983-11-15
SE8007427L (sv)	1980-10-22
DK446482A (da)	1982-10-08
IT1151077B (it)	1986-12-17
FR2455609B1 (da)	1983-07-01
CH654015A5 (de)	1986-01-31
JPH0142944B2 (da)	1989-09-18
CH653018A5 (de)	1985-12-13
DK156635B (da)	1989-09-18
FR2450814A1 (fr)	1980-10-03
GB2044770A (en)	1980-10-22
US4196133A (en)	1980-04-01
JPS63183559A (ja)	1988-07-28
IE49532B1 (en)	1985-10-16
DK156726B (da)	1989-09-25
DK156635C (da)	1990-02-12
FR2455609A1 (fr)	1980-11-28
DK467780A (da)	1980-11-04
JPS6310946B2 (da)	1988-03-10
BE882036A (fr)	1980-07-01
JPS56500064A (da)	1981-01-22
WO1980001915A1 (en)	1980-09-18

Legal Events

Date	Code	Title	Description
1992-06-29	PBP	Patent lapsed

Publication	Publication Date	Title
FI850198L (fi)	1985-01-16	Expressionsplasmid.
FI870555A7 (fi)	1987-02-11	Nya -laktamasinhibitorfoereningar.
ES256673Y (es)	1981-12-16	Guardavistas.
ES254327Y (es)	1982-02-16	Portillon.
FI73548B (fi)	1987-06-30	Oeverstroemskyddskrets foer effekttransistor.
DK156644C (da)	1990-02-12	3-acetoxy-24,24-difluor-25-hydroxy-cholestan-5,7-dien
FI872955A0 (fi)	1987-07-03	1-cyklohexenylmetyletyl-pyrrolidinderivat.
FI803403A7 (fi)	1981-05-01	Uusia pyridotienotriatsideja.
NO802888L (no)	1981-04-02	2-klor-4,5-disubstituerte-thiazoler
IT8023118A0 (it)	1980-06-30	Immagazzinatore.
IT1209290B (it)	1989-07-16	Tetraidrofuran-derivato.
FI854729A0 (fi)	1985-11-28	Vedhuggningsmaskin.
NO144471C (no)	1981-09-09	Trinse for skistav.
IT8023753A0 (it)	1980-07-28	Colecalciferol-derivati.
IT7920853A0 (it)	1979-03-09	Piretroidi.
IT8025832A0 (it)	1980-11-07	Fenossifeniluree.
FI73539B (fi)	1987-06-30	Multiplexanslutningsenhet foer en digitalstation.
IT8026120A0 (it)	1980-11-20	Mercaptoorganopolisilossani.
IT8021496A0 (it)	1980-04-18	N-alchinilanilidi.
BE881358A (fr)	1980-05-16	25-hydroxycholecalciferol-26,23-lactone
NO812109L (no)	1981-06-19	Z-profilfoeringsinnretning.
ES241403Y (es)	1979-10-16	Caja-archivador.
ES241938Y (es)	1979-11-16	Parrilla gratinadora.
ES241511Y (es)	1979-11-01	Papelera-cenicero.
ES241690Y (es)	1979-11-01	Estuche-expositor.