DK165010C - Fremgangsmaade til fremstilling af 7-halogen-7-deoxylincomyciner ud fra lincomycin eller en dermed analog forbindelse - Google Patents

Fremgangsmaade til fremstilling af 7-halogen-7-deoxylincomyciner ud fra lincomycin eller en dermed analog forbindelse

Info

Publication number: DK165010C
Authority: DK; Denmark
Prior art keywords: preparing; lincomycin; deoxylincomycines; analogical; halogen
Prior art date: 1984-11-29

Application number

DK542785A

Other languages

Danish (da)

English (en)

Other versions

DK542785A (da

DK165010B (da

DK542785D0 (da

Inventor

Douglas Alan Livingston

Janet Elizabeth Petre

Original Assignee

Upjohn Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-11-29

Filing date

1985-11-22

Publication date

1993-02-22

1985-11-22 Application filed by Upjohn Co filed Critical Upjohn Co

1985-11-22 Publication of DK542785D0 publication Critical patent/DK542785D0/da

1986-05-30 Publication of DK542785A publication Critical patent/DK542785A/da

1992-09-28 Publication of DK165010B publication Critical patent/DK165010B/da

1993-02-22 Application granted granted Critical

1993-02-22 Publication of DK165010C publication Critical patent/DK165010C/da

Links

OJMMVQQUTAEWLP-UHFFFAOYSA-N Lincomycin Natural products CN1CC(CCC)CC1C(=O)NC(C(C)O)C1C(O)C(O)C(O)C(SC)O1 OJMMVQQUTAEWLP-UHFFFAOYSA-N 0.000 title abstract 2
OJMMVQQUTAEWLP-KIDUDLJLSA-N lincomycin Chemical compound CN1C[C@H](CCC)C[C@H]1C(=O)N[C@H]([C@@H](C)O)[C@@H]1[C@H](O)[C@H](O)[C@@H](O)[C@@H](SC)O1 OJMMVQQUTAEWLP-KIDUDLJLSA-N 0.000 title abstract 2
229960005287 lincomycin Drugs 0.000 title abstract 2
150000001875 compounds Chemical class 0.000 title 1
ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 abstract 3
238000004519 manufacturing process Methods 0.000 abstract 1
-1 thionyl halide Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/14—Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical
- C07H15/16—Lincomycin; Derivatives thereof

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Crystallography & Structural Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Peptides Or Proteins (AREA)
Cephalosporin Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Indole Compounds (AREA)

DK542785A 1984-11-29 1985-11-22 Fremgangsmaade til fremstilling af 7-halogen-7-deoxylincomyciner ud fra lincomycin eller en dermed analog forbindelse DK165010C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US67615784A	1984-11-29	1984-11-29
US67615784		1984-11-29

Publications (4)

Publication Number	Publication Date
DK542785D0 DK542785D0 (da)	1985-11-22
DK542785A DK542785A (da)	1986-05-30
DK165010B DK165010B (da)	1992-09-28
DK165010C true DK165010C (da)	1993-02-22

Family

ID=24713464

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK542785A DK165010C (da)	1984-11-29	1985-11-22	Fremgangsmaade til fremstilling af 7-halogen-7-deoxylincomyciner ud fra lincomycin eller en dermed analog forbindelse

Country Status (19)

Country	Link
US (1)	US4710565A (fr)
EP (1)	EP0183505B1 (fr)
JP (1)	JPH0649714B2 (fr)
KR (1)	KR930003492B1 (fr)
CN (2)	CN1004002B (fr)
AT (1)	ATE50265T1 (fr)
AU (1)	AU574232B2 (fr)
CA (1)	CA1238319A (fr)
DE (1)	DE3575930D1 (fr)
DK (1)	DK165010C (fr)
ES (1)	ES8605817A1 (fr)
FI (1)	FI78708C (fr)
GR (1)	GR852861B (fr)
HU (1)	HU199497B (fr)
IL (1)	IL76778A (fr)
MX (1)	MX162251A (fr)
PT (1)	PT81496B (fr)
SU (1)	SU1405705A3 (fr)
ZA (1)	ZA858117B (fr)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4568741A (en) *	1984-05-15	1986-02-04	The Upjohn Company	Synthesis of 7-halo-7-deoxylincomycins
JP2531876Y2 (ja) *	1988-12-15	1997-04-09	日東工器株式会社	電磁式ダイアフラムポンプ用マグネットホルダ
JP2531877Y2 (ja) *	1988-12-15	1997-04-09	日東工器株式会社	電磁式ダイアフラムポンプ
JP2544782Y2 (ja) *	1988-12-27	1997-08-20	日東工器株式会社	電磁式ダイアフラムポンプ用マグネットホルダ
US6544555B2 (en)	2000-02-24	2003-04-08	Advancis Pharmaceutical Corp.	Antibiotic product, use and formulation thereof
US6565882B2 (en)	2000-02-24	2003-05-20	Advancis Pharmaceutical Corp	Antibiotic composition with inhibitor
US20020068078A1 (en)	2000-10-13	2002-06-06	Rudnic Edward M.	Antifungal product, use and formulation thereof
US6541014B2 (en)	2000-10-13	2003-04-01	Advancis Pharmaceutical Corp.	Antiviral product, use and formulation thereof
US20030073648A1 (en) *	2001-08-28	2003-04-17	Chao Robert S.	Crystaline clindamycin free base
US7164011B2 (en) *	2002-08-15	2007-01-16	Vicuron Pharmaceuticals, Inc.	Lincomycin derivatives possessing antibacterial activity
US7199105B2 (en) *	2002-08-15	2007-04-03	Vicuron Pharmaceuticals, Inc.	Lincomycin derivatives possessing antibacterial activity
ES2637956T3 (es)	2003-01-24	2017-10-18	Stiefel Research Australia Pty Ltd	Espuma farmacéutica
US7199106B2 (en)	2003-06-17	2007-04-03	Vicuron Pharmaceuticals, Inc.	Lincomycin derivatives possessing antimicrobial activity
US7256177B2 (en)	2003-06-17	2007-08-14	Vicuron Pharmaceuticals, Inc.	Lincomycin derivatives possessing antibacterial activity
AU2004258953B2 (en)	2003-07-21	2011-02-10	Shionogi, Inc.	Antibiotic product, use and formulation thereof
AU2004258949B2 (en)	2003-07-21	2011-02-10	Shionogi, Inc.	Antibiotic product, use and formulation thereof
JP2006528185A (ja)	2003-07-21	2006-12-14	アドバンシスファーマスーティカルコーポレイション	抗生物質製剤、その使用法及び作成方法
CA2535177A1 (fr)	2003-08-11	2005-02-24	Advancis Pharmaceutical Corporation	Pastille robuste
US8062672B2 (en)	2003-08-12	2011-11-22	Shionogi Inc.	Antibiotic product, use and formulation thereof
AU2004270170B2 (en)	2003-08-29	2011-01-27	Shionogi, Inc.	Antibiotic product, use and formulation thereof
CA2538064C (fr)	2003-09-15	2013-12-17	Advancis Pharmaceutical Corporation	Antibiotique, son utilisation et sa formulation
US7361743B2 (en) *	2004-02-11	2008-04-22	Pfizer Inc	Lincomycin derivatives possessing antibacterial activity
CA2572292A1 (fr)	2004-07-02	2006-02-09	Advancis Pharmaceutical Corporation	Comprime pour distribution par impulsion
US8778924B2 (en)	2006-12-04	2014-07-15	Shionogi Inc.	Modified release amoxicillin products
US8357394B2 (en)	2005-12-08	2013-01-22	Shionogi Inc.	Compositions and methods for improved efficacy of penicillin-type antibiotics
EA200801745A1 (ru) *	2006-02-28	2009-02-27	В.Б. Медикэр Пвт. Лтд.	Новый хлорирующий реагент и новый способ для хлорирования сахаров с использованием тионил хлорида
EP2010133B1 (fr)	2006-03-31	2016-05-04	Stiefel Research Australia Pty Ltd	Gel de suspension moussant
US8299052B2 (en)	2006-05-05	2012-10-30	Shionogi Inc.	Pharmaceutical compositions and methods for improved bacterial eradication
CN101205245B (zh) *	2007-12-06	2011-04-06	河南天方药业股份有限公司	盐酸克林霉素的制备方法
CN102675146A (zh) *	2012-05-22	2012-09-19	山东凯盛新材料股份有限公司	新型固体氯化剂（氯亚甲基）二甲基氯化铵的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3496163A (en) *	1965-02-08	1970-02-17	Upjohn Co	7-halo-7-deoxylincomycins and process for preparing the same
US3435025A (en) *	1966-03-18	1969-03-25	Upjohn Co	7-deoxylincomycin and analogs and isomers thereof and process for making the same
US3580904A (en) *	1969-04-03	1971-05-25	Upjohn Co	7-halo-7-deoxy-lincomycin derivatives
US3574186A (en) *	1969-10-08	1971-04-06	Upjohn Co	Process for making 7-chloro-7-deoxylincomycin and related compounds and novel intermediates produced therein
US4568741A (en) *	1984-05-15	1986-02-04	The Upjohn Company	Synthesis of 7-halo-7-deoxylincomycins

1985
- 1985-04-01 CN CN85101921.8A patent/CN1004002B/zh not_active Expired
- 1985-10-11 CA CA000492862A patent/CA1238319A/fr not_active Expired
- 1985-10-18 AU AU48837/85A patent/AU574232B2/en not_active Expired
- 1985-10-22 ZA ZA858117A patent/ZA858117B/xx unknown
- 1985-10-22 IL IL76778A patent/IL76778A/xx not_active IP Right Cessation
- 1985-10-23 ES ES548152A patent/ES8605817A1/es not_active Expired
- 1985-11-14 PT PT81496A patent/PT81496B/pt unknown
- 1985-11-14 CN CN85108244A patent/CN1016694B/zh not_active Expired
- 1985-11-19 MX MX661A patent/MX162251A/es unknown
- 1985-11-22 DK DK542785A patent/DK165010C/da not_active IP Right Cessation
- 1985-11-25 EP EP85308539A patent/EP0183505B1/fr not_active Expired - Lifetime
- 1985-11-25 AT AT85308539T patent/ATE50265T1/de not_active IP Right Cessation
- 1985-11-25 DE DE8585308539T patent/DE3575930D1/de not_active Expired - Lifetime
- 1985-11-27 GR GR852861A patent/GR852861B/el unknown
- 1985-11-28 SU SU853984283A patent/SU1405705A3/ru active
- 1985-11-28 JP JP60269229A patent/JPH0649714B2/ja not_active Expired - Lifetime
- 1985-11-28 FI FI854711A patent/FI78708C/fi not_active IP Right Cessation
- 1985-11-28 KR KR1019850008893A patent/KR930003492B1/ko not_active Expired - Lifetime
- 1985-11-29 HU HU854580A patent/HU199497B/hu unknown
1986
- 1986-01-24 US US06/822,044 patent/US4710565A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
CN85101921A (zh)	1987-01-10
DK542785A (da)	1986-05-30
FI854711A0 (fi)	1985-11-28
AU4883785A (en)	1986-06-05
PT81496A (en)	1985-12-01
DK165010B (da)	1992-09-28
EP0183505B1 (fr)	1990-02-07
CA1238319A (fr)	1988-06-21
KR930003492B1 (ko)	1993-05-01
GR852861B (fr)	1986-03-28
KR860004077A (ko)	1986-06-16
CN1004002B (zh)	1989-04-26
FI854711L (fi)	1986-05-30
EP0183505A2 (fr)	1986-06-04
IL76778A (en)	1991-09-16
US4710565A (en)	1987-12-01
ES548152A0 (es)	1986-04-01
DK542785D0 (da)	1985-11-22
FI78708C (fi)	1989-09-11
IL76778A0 (en)	1986-02-28
ZA858117B (en)	1986-06-25
CN85108244A (zh)	1986-08-20
PT81496B (pt)	1987-11-11
ES8605817A1 (es)	1986-04-01
JPS61137892A (ja)	1986-06-25
FI78708B (fi)	1989-05-31
HU199497B (en)	1990-02-28
JPH0649714B2 (ja)	1994-06-29
ATE50265T1 (de)	1990-02-15
MX162251A (es)	1991-04-17
SU1405705A3 (ru)	1988-06-23
AU574232B2 (en)	1988-06-30
DE3575930D1 (de)	1990-03-15
EP0183505A3 (en)	1987-06-24
HUT40806A (en)	1987-02-27
CN1016694B (zh)	1992-05-20

Legal Events

Date	Code	Title	Description
2005-12-12	PUP	Patent expired

Publication	Publication Date	Title
DK165010C (da)	1993-02-22	Fremgangsmaade til fremstilling af 7-halogen-7-deoxylincomyciner ud fra lincomycin eller en dermed analog forbindelse
ES2103433T3 (es)	1997-09-16	Procedimiento para preparar derivados de 1-halo-2-desoxi-2,2-difluoro-d-ribofuranosilo enriquecidos en anomero alfa.
DK0655454T3 (da)	2001-10-08	Fremgangsmåde til fremstilling af 2,2-difluorketensilylacetaler og alfa,alfa-difluor-beta-silyloxy-1,3-dioxolan-4-propansyreestere
KR890700388A (ko)	1989-04-24	대기로부터 휘발성 화합물을 회수하는 방법
DK87190D0 (da)	1990-04-06	Fremgangsmaade til at regulere plantevaekst under anvendelse af svovlholdige organiske syrer
DE69131286D1 (de)	1999-07-08	L-Gulono-Gamma-Lacton Dehydrogenase
DE3586926D1 (de)	1993-02-11	Schweinepankreas-elastase.
DK168681A (da)	1981-10-16	Fremgangsmaade til fremstilling af carbonhydrider ud fra skiferler skiferolie og lignende udgangsmaterialer
ATE9564T1 (de)	1984-10-15	Schiene zum befestigen biegsamer, blattfoermiger strukturen.
MX9203684A (es)	1992-09-01	Benzotiazepinas.
DK443788D0 (da)	1988-08-09	Fremgangsmaade til formering af plantevarianter
DE3876266D1 (de)	1993-01-14	Schaltung zur korrektur der moewenfluegelverzerrung.
DK0502735T3 (da)	1996-04-09	Fremgangsmåde og mellemprodukter til fremstilling af 2,2-dimethyl-2,3-dihydrobenzofuran-7- carboxylsyrer
DK93884D0 (da)	1984-02-23	Fremgangsmade til fremstilling af 1,5-dibeskyttede-1,5,10-triazadecaner, mellemprodukter derfor samt disses fremstilling
EA200000705A1 (ru)	2000-12-25	Промежуточные соединения и способ синтеза 17-замещенных 16.бета.-арилокси 4-азастероидов
FR2571370B1 (fr)	1986-11-21	Procede de preparation de diamines substituees
DK87290D0 (da)	1990-04-06	Fremgangsmaade til at regulere plantevaekst under anvendelse af xanthater
DK281385D0 (da)	1985-06-21	Fremgangsmaade til fremstilling af hydroquinonmonocarboxylater
DK564588A (da)	1988-10-10	Fremgangsmaade til udvinding af flygtige forbindelser fra atmosfaeren
SE8202388L (sv)	1982-10-17	Forfarande for riktning av sagblad
DK51893A (da)	1993-05-05	1,2,3-thiadiazol-4-thio-forbindelser
SE8704332D0 (sv)	1987-11-05	Hothouse for cultivation
DE3770441D1 (de)	1991-07-04	Korrelierter abtastverstaerker.
GR851013B (fr)	1985-11-25