DK165778A - Fremgangsmaade til fremstilling af analoge af ergotalkaloider - Google Patents

Fremgangsmaade til fremstilling af analoge af ergotalkaloider

Info

Publication number
DK165778A
DK165778A DK165778A DK165778A DK165778A DK 165778 A DK165778 A DK 165778A DK 165778 A DK165778 A DK 165778A DK 165778 A DK165778 A DK 165778A DK 165778 A DK165778 A DK 165778A
Authority
DK
Denmark
Prior art keywords
kaloid
ergotal
analogs
preparing
procedure
Prior art date
Application number
DK165778A
Other languages
English (en)
Other versions
DK145701C (da
DK145701B (da
Inventor
E Beacco
M L Blanchi
A Minghetti
C Spalla
Original Assignee
Farmaceutici Italia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmaceutici Italia filed Critical Farmaceutici Italia
Publication of DK165778A publication Critical patent/DK165778A/da
Publication of DK145701B publication Critical patent/DK145701B/da
Application granted granted Critical
Publication of DK145701C publication Critical patent/DK145701C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/182—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system
    • C12P17/183—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system containing an indolo[4,3-F,G]quinoleine nucleus, e.g. compound containing the lysergic acid nucleus as well as the dimeric ergot nucleus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/02—Ergot alkaloids of the cyclic peptide type

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK165778A 1977-04-19 1978-04-17 Fremgangsmaade til fremstilling af ergotalkaloider DK145701C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB16096/77A GB1584464A (en) 1977-04-19 1977-04-19 Ergot alkaloids
GB1609677 2016-06-02

Publications (3)

Publication Number Publication Date
DK165778A true DK165778A (da) 1978-10-20
DK145701B DK145701B (da) 1983-01-31
DK145701C DK145701C (da) 1983-07-18

Family

ID=10071128

Family Applications (1)

Application Number Title Priority Date Filing Date
DK165778A DK145701C (da) 1977-04-19 1978-04-17 Fremgangsmaade til fremstilling af ergotalkaloider

Country Status (16)

Country Link
US (1) US4230854A (da)
JP (1) JPS53132599A (da)
AT (1) AT369783B (da)
BE (1) BE865921A (da)
CA (1) CA1113410A (da)
CH (1) CH637658A5 (da)
CS (1) CS212760B2 (da)
DE (1) DE2816773A1 (da)
DK (1) DK145701C (da)
FR (1) FR2387989A1 (da)
GB (1) GB1584464A (da)
HU (1) HU175173B (da)
IE (1) IE46797B1 (da)
NL (1) NL7804174A (da)
SE (1) SE7804362L (da)
SU (1) SU735154A3 (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH646166A5 (it) * 1980-09-30 1984-11-15 Linnea Sa Procedimento di sintesi parziale della vincamina e di alcaloidi indolici correlati.
FR2499589B1 (fr) * 1981-02-06 1985-11-15 Richter Gedeon Vegyeszet Procede pour regler la quantite et les proportions des alcaloides qui se forment lors de la fermentation
US4390625A (en) 1981-02-06 1983-06-28 Richter Gedeon Vegyeszeti Gyar Rt Method for controlling the amount and distribution of alkaloids formed in a fermentation process
CH649300A5 (de) * 1981-08-07 1985-05-15 Sandoz Ag Ergopeptinderivate, ihre herstellung und verwendung.
HU190141B (en) * 1983-08-10 1986-08-28 Richter Gedeon Vegyeszeti Gyar Rt,Hu New process for production of clavin-type rye-smut alcaloids
US5891885A (en) * 1996-10-09 1999-04-06 Algos Pharmaceutical Corporation Method for treating migraine
EP2515654A4 (en) * 2009-12-23 2013-04-24 Map Pharmaceuticals Inc NEW ERGOLINANALOGA
EP2723735A4 (en) * 2011-06-23 2015-02-18 Map Pharmaceuticals Inc NOVEL ANALOGUES OF FLUORO-ERGOLINE
AU2012355982A1 (en) 2011-12-19 2014-07-10 Map Pharmaceuticals, Inc. Novel iso-ergoline derivatives
US8946420B2 (en) 2011-12-21 2015-02-03 Map Pharmaceuticals, Inc. Neuromodulatory compounds
US9012640B2 (en) 2012-06-22 2015-04-21 Map Pharmaceuticals, Inc. Cabergoline derivatives
KR20230024378A (ko) 2020-06-12 2023-02-20 벡클리 싸이테크 리미티드 5-메톡시-n, n-디메틸트립타민의 벤조에이트 염을 포함하는 조성물
WO2022153266A1 (en) 2021-01-15 2022-07-21 Beckley Psytech Limited Ergoline analogues
GB202212116D0 (en) 2022-08-19 2022-10-05 Beckley Psytech Ltd Pharmaceutically acceptable salts and Compositions thereof
US12264131B2 (en) 2022-08-19 2025-04-01 Beckley Psytech Limited Pharmaceutically acceptable salts and compositions thereof
US12246005B2 (en) 2023-06-13 2025-03-11 Beckley Psytech Limited 5-methoxy-n,n-dimethyltryptamine (5-MeO-DMT) formulations

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH508628A (de) * 1968-06-25 1971-06-15 Sandoz Ag Verfahren zur Herstellung neuer heterocyclischer Verbindungen
CH534683A (de) * 1970-05-26 1973-03-15 Sandoz Ag Verfahren zur Herstellung neuer Mutterkornpeptidalkaloide
DK140017B (da) * 1973-07-09 1979-06-05 Sandoz Ag Fremgangsmåde til fremstilling af octahydro-oxazolo(3,2-a)pyrrolo(2,1-c)pyrazinderivater.
HU172649B (hu) * 1975-04-24 1978-11-28 Gyogyszerkutato Intezet Sposob poluchenija novykh biologicheski aktivnykh lizergamidov
CH619468A5 (da) * 1976-01-12 1980-09-30 Sandoz Ag
US4124712A (en) * 1976-09-06 1978-11-07 Sandoz Ltd. Ergot peptide alkaloid derivatives

Also Published As

Publication number Publication date
FR2387989A1 (fr) 1978-11-17
DE2816773A1 (de) 1978-10-26
FR2387989B1 (da) 1980-07-04
SE7804362L (sv) 1978-10-20
NL7804174A (nl) 1978-10-23
ATA260378A (de) 1982-06-15
JPS53132599A (en) 1978-11-18
IE780759L (en) 1978-10-19
HU175173B (hu) 1980-05-28
AT369783B (de) 1983-01-25
CH637658A5 (it) 1983-08-15
IE46797B1 (en) 1983-09-21
CS212760B2 (en) 1982-03-26
CA1113410A (en) 1981-12-01
SU735154A3 (ru) 1980-05-15
GB1584464A (en) 1981-02-11
US4230854A (en) 1980-10-28
DK145701C (da) 1983-07-18
DK145701B (da) 1983-01-31
BE865921A (fr) 1978-07-31

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Legal Events

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PBP Patent lapsed