DK166986A - Fremgangsmaade til racemisering af et optisk aktivt n-benzylidenamimosyreamid - Google Patents

Fremgangsmaade til racemisering af et optisk aktivt n-benzylidenamimosyreamid Download PDF

Info

Publication number: DK166986A
Authority: DK; Denmark
Prior art keywords: amino; acid amide; solution; acid; benzylidene
Prior art date: 1985-04-12

Application number

DK166986A

Other languages

Danish (da)

English (en)

Other versions

DK166986D0 (da

Inventor

Wilhelmus Hubertus Jos Boesten

Hans Egbert Schoemaker

Bernardus Henricus Nico Dassen

Original Assignee

Stamicarbon

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-04-12

Filing date

1986-04-11

Publication date

1986-10-13

1986-04-11 Application filed by Stamicarbon filed Critical Stamicarbon

1986-04-11 Publication of DK166986D0 publication Critical patent/DK166986D0/da

1986-10-13 Publication of DK166986A publication Critical patent/DK166986A/da

Links

238000000034 method Methods 0.000 title abstract 3
238000009434 installation Methods 0.000 title 1
235000021243 milk fat Nutrition 0.000 title 1
QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 2
HUMNYLRZRPPJDN-UHFFFAOYSA-N benzaldehyde Chemical compound O=CC1=CC=CC=C1 HUMNYLRZRPPJDN-UHFFFAOYSA-N 0.000 abstract 2
239000002244 precipitate Substances 0.000 abstract 2
150000008574 D-amino acids Chemical class 0.000 abstract 1
102000004190 Enzymes Human genes 0.000 abstract 1
108090000790 Enzymes Proteins 0.000 abstract 1
150000008575 L-amino acids Chemical class 0.000 abstract 1
241000589776 Pseudomonas putida Species 0.000 abstract 1
230000002255 enzymatic effect Effects 0.000 abstract 1
238000002955 isolation Methods 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
239000003960 organic solvent Substances 0.000 abstract 1
QNGNSVIICDLXHT-UHFFFAOYSA-N para-ethylbenzaldehyde Natural products CCC1=CC=C(C=O)C=C1 QNGNSVIICDLXHT-UHFFFAOYSA-N 0.000 abstract 1
238000002360 preparation method Methods 0.000 abstract 1
OVARTBFNCCXQKS-UHFFFAOYSA-N propan-2-one;hydrate Chemical compound O.CC(C)=O OVARTBFNCCXQKS-UHFFFAOYSA-N 0.000 abstract 1
238000000926 separation method Methods 0.000 abstract 1
235000011149 sulphuric acid Nutrition 0.000 abstract 1
239000001117 sulphuric acid Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
- C12P41/007—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures by reactions involving acyl derivatives of racemic amines

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Health & Medical Sciences (AREA)
General Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Microbiology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Analytical Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Seeds, Soups, And Other Foods (AREA)
Edible Oils And Fats (AREA)

DK166986A 1985-04-12 1986-04-11 Fremgangsmaade til racemisering af et optisk aktivt n-benzylidenamimosyreamid DK166986A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
NL8501093A NL8501093A (nl)	1985-04-12	1985-04-12	Werkwijze voor het racemiseren van een optisch aktief n- benzylideenaminozuuramide.

Publications (2)

Publication Number	Publication Date
DK166986D0 DK166986D0 (da)	1986-04-11
DK166986A true DK166986A (da)	1986-10-13

Family

ID=19845833

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK166986A DK166986A (da)	1985-04-12	1986-04-11	Fremgangsmaade til racemisering af et optisk aktivt n-benzylidenamimosyreamid

Country Status (13)

Country	Link
US (2)	US4847412A (de)
EP (1)	EP0199407B1 (de)
JP (1)	JPH0655702B2 (de)
AT (1)	ATE50241T1 (de)
BR (1)	BR8601656A (de)
CA (1)	CA1292434C (de)
DE (1)	DE3668883D1 (de)
DK (1)	DK166986A (de)
ES (1)	ES8706837A1 (de)
IL (1)	IL78462A0 (de)
NL (1)	NL8501093A (de)
PT (1)	PT82379B (de)
ZA (1)	ZA862746B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL8501093A (nl) *	1985-04-12	1986-11-03	Stamicarbon	Werkwijze voor het racemiseren van een optisch aktief n- benzylideenaminozuuramide.
ES2051892T3 (es) *	1987-08-17	1994-07-01	Novo Industri As	Procedimiento para preparar productos quimicos organicos.
NL8800260A (nl) *	1988-02-04	1989-09-01	Stamicarbon	Alpha-n-hydroxyaminozuren, amiden en andere derivaten daarvan.
DE3816063A1 (de) *	1988-05-06	1989-11-23	Schering Ag	Verfahren zur herstellung von l-aminosaeuren und aminosaeure-amiden
EP0383403A1 (de) *	1989-02-16	1990-08-22	Stamicarbon B.V.	Verfahren zur Herstellung von organischen chemischen Produkten
FR2655660B1 (fr) *	1989-12-11	1992-03-20	Rhone Poulenc Sante	Nouveaux polypeptides, sequences d'adn permettant leur expression, procede de preparation et leur utilisation.
NL9000387A (nl)	1990-02-16	1991-09-16	Stamicarbon	Werkwijze voor het racemiseren van een optisch aktief aminozuuramide.
FR2661909B1 (fr) *	1990-05-09	1997-08-14	Inst Nat Sante Rech Med	Nouveaux composes agonistes du recepteur h3 de l'histamine a usage therapeutique, compositions pharmaceutiques agissant comme agonistes dudit recepteur et procede de preparation.
NL9201230A (nl) *	1992-07-09	1994-02-01	Dsm Nv	Werkwijze voor de bereiding van optisch aktief methionineamide.
JPH08157437A (ja) *	1994-12-08	1996-06-18	Ajinomoto Co Inc	Ｄ−アミノ酸−Ｎ−（Ｓ）−α−アルキルベンジルアミドの製造法
DE19529293A1 (de) *	1995-08-09	1997-02-13	Bayer Ag	Verfahren zur Herstellung von racemischen Amino-Derivaten
HU226421B1 (en) *	1998-11-09	2008-12-29	Sanofi Aventis	Process for racemizing optically active 2-(2-chlorophenyl)-2-(2-(2-thienyl)-ethylamino)-acetamides
NL1015495C2 (nl) *	2000-06-22	2001-12-28	Dsm Nv	Werkwijze voor het racemiseren van een enantiomeer verrijkte schiffse base van een aminozuuramide.
NL1015715C2 (nl) *	2000-07-14	2002-01-17	Dsm Nv	Werkwijze voor de bereiding van (schiffse basen van) alfa-alkyl-alfa-aminozuuramiden.
JP2002241315A (ja) *	2001-02-14	2002-08-28	Mitsubishi Gas Chem Co Inc	光学活性ｎ−アルキル−アミノ酸アミドのラセミ化法
CA2610776C (en) *	2005-07-29	2010-09-14	Nagase & Co., Ltd.	Process for production of mono-substituted alkylated compound using aldimine or derivative thereof
CN101723773B (zh) *	2009-11-27	2011-09-21	天津大学	高纯度n-乙酰-dl-氨基酸的制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US440792A (en) *		1890-11-18		Process of making hydrogen peroxide
US2945883A (en) *	1953-05-20	1960-07-19	Farmaceutici Italia	Process for converting optically active aminodiols into racemic aminodiols by oxidation followed by racemization
BE795874A (fr) *	1972-02-25	1973-08-23	Glaxo Lab Ltd	Procede de preparation d'esters optiquement actifs d'alpha-amino-acides
NL182954C (nl) *	1975-08-20	1988-06-16	Stamicarbon	Werkwijze voor het bereiden van alfa-aminozuuramide.
NL7514300A (nl) *	1975-12-09	1977-06-13	Stamicarbon	Werkwijze voor de bereiding van optisch actief fenylglycineamide.
NL187110C (nl) *	1976-11-10	1991-06-03	Stamicarbon	Werkwijze voor het scheiden van een mengsel van een optisch aktief fenylglycine-amide en een optisch aktief fenylglycine.
NL188037C (nl) *	1977-11-30	1992-03-16	Stamicarbon	Werkwijze voor de bereiding van dl-fenylglycine-amide via racemisatie.
FR2430413A1 (fr) *	1978-07-07	1980-02-01	Anvar	Procede de preparation d'alpha-aminoacides optiquement actifs, et leurs derives
US4401820A (en) *	1981-01-23	1983-08-30	Tanabe Seiyaku Co., Ltd.	Process for racemizing optically active α-amino acids or a salt thereof
FR2523961B1 (fr) *	1982-03-23	1985-08-30	Centre Nat Rech Scient	Procede de preparation d'un alpha-amino-acide libre l
NL8501093A (nl) *	1985-04-12	1986-11-03	Stamicarbon	Werkwijze voor het racemiseren van een optisch aktief n- benzylideenaminozuuramide.
US4713470A (en) *	1985-05-22	1987-12-15	Stauffer Chemical Company	Racemization of amino acids

1985
- 1985-04-12 NL NL8501093A patent/NL8501093A/nl not_active Application Discontinuation
1986
- 1986-04-10 JP JP61081252A patent/JPH0655702B2/ja not_active Expired - Fee Related
- 1986-04-10 US US06/850,157 patent/US4847412A/en not_active Expired - Lifetime
- 1986-04-10 EP EP86200603A patent/EP0199407B1/de not_active Expired - Lifetime
- 1986-04-10 DE DE8686200603T patent/DE3668883D1/de not_active Expired - Lifetime
- 1986-04-10 CA CA000506281A patent/CA1292434C/en not_active Expired - Lifetime
- 1986-04-10 IL IL78462A patent/IL78462A0/xx unknown
- 1986-04-10 AT AT86200603T patent/ATE50241T1/de not_active IP Right Cessation
- 1986-04-11 ZA ZA862746A patent/ZA862746B/xx unknown
- 1986-04-11 ES ES553903A patent/ES8706837A1/es not_active Expired
- 1986-04-11 PT PT82379A patent/PT82379B/pt unknown
- 1986-04-11 DK DK166986A patent/DK166986A/da not_active Application Discontinuation
- 1986-04-11 BR BR8601656A patent/BR8601656A/pt unknown
1989
- 1989-04-03 US US07/332,576 patent/US5047585A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
BR8601656A (pt)	1986-12-16
CA1292434C (en)	1991-11-26
ES8706837A1 (es)	1987-07-01
IL78462A0 (en)	1986-08-31
JPS61238770A (ja)	1986-10-24
PT82379B (en)	1987-09-10
NL8501093A (nl)	1986-11-03
PT82379A (en)	1986-05-01
US4847412A (en)	1989-07-11
DK166986D0 (da)	1986-04-11
EP0199407A1 (de)	1986-10-29
DE3668883D1 (de)	1990-03-15
ATE50241T1 (de)	1990-02-15
US5047585A (en)	1991-09-10
EP0199407B1 (de)	1990-02-07
ES553903A0 (es)	1987-07-01
JPH0655702B2 (ja)	1994-07-27
ZA862746B (en)	1986-11-26

Legal Events

Date	Code	Title	Description
1993-08-16	B1	Patent granted (law 1993)
1993-12-27	AHB	Application shelved due to non-payment

Publication	Publication Date	Title
DK166986A (da)	1986-10-13	Fremgangsmaade til racemisering af et optisk aktivt n-benzylidenamimosyreamid
US4857462A (en)	1989-08-15	Process for obtaining D(+)-naproxen
IE870240L (en)	1987-07-31	Benzhydrylsulphinylacetamide
US4080259A (en)	1978-03-21	Process of preparing L and D α-amino acids by enzyme treatment of DL-α-amino acid amide
EP0043211B1 (de)	1984-05-09	Verfahren zur Herstellung optisch aktiver Tryptophane
ES2076398T3 (es)	1995-11-01	Procedimiento para la preparacion de sales de la l-ornitina.
TW347395B (en)	1998-12-11	Method for the production of nitrile rubber
AU4457385A (en)	1986-01-09	Synthesis of double stranded nucleic acids from single stranded nucleic acids
WO1988001298A3 (en)	1988-04-07	Enzymatic membrane method for the synthesis and separation of peptides
CA2239537A1 (en)	1997-06-12	Process for the preparation of substituted aryl lactic acid containing cyclodepsipeptides with 24 ring atoms
DE3378206D1 (en)	1988-11-17	Process for the preparation of a free alpha-l-amino acid
HUT39414A (en)	1986-09-29	Process for preparing aromatic l-aminoacids
CA2009295A1 (en)	1990-08-06	Process for the enzymatic resolution of 2-amino-4-methylphosphinobutyric acid derivatives
SE8403933D0 (sv)	1984-07-31	Production of l-amino acids from alpha-keto acids
GB1525907A (en)	1978-09-27	Ureidoacetohydroxamic acids
ATE35826T1 (de)	1988-08-15	Verfahren zur herstellung von l-alphaaminos\|uren.
ES2085487T3 (es)	1996-06-01	Un procedimiento para la preparacion de acidos 2-alcanoicos enantiomericos.
Onderka et al.	1969	Stereospecificity of the 3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase reaction
EP0805211A3 (de)	1998-12-02	Verfahren zur Herstellung von optisch-aktiven Aminopolycarbonsäuren
CA2123081A1 (en)	1993-05-13	Enzymatic preparation of n-(phosphonomethyl) glycine
EP0997535A3 (de)	2000-10-18	Stereoselektive mikrobielle Reduktion eines razemischen Tetralons
ATE17230T1 (de)	1986-01-15	Verfahren zur herstellung von 2'-4'-difluor-4hydroxy-(1,1'-diphenyl)-carbonsaeure.
US3703439A (en)	1972-11-21	Process for the preparation of l-beta-(3,4-dihydroxyphenyl)-alpha-alanine by fermentation
WO1999003821A3 (en)	1999-05-20	Process for isomerisation of tilidine
AU4958296A (en)	1996-10-16	Process for the recovery of ampicillin