DK167768B1 - Fluorescerende mono- eller polyamider af en aminodicarboxylsyre og en tetrapyrrolforbindelse indeholdende mindst en carboxylgruppe samt terapeutisk praeparat indeholdende disse forbindelser - Google Patents

Fluorescerende mono- eller polyamider af en aminodicarboxylsyre og en tetrapyrrolforbindelse indeholdende mindst en carboxylgruppe samt terapeutisk praeparat indeholdende disse forbindelser Download PDF

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Publication number
DK167768B1
DK167768B1 DK326785A DK326785A DK167768B1 DK 167768 B1 DK167768 B1 DK 167768B1 DK 326785 A DK326785 A DK 326785A DK 326785 A DK326785 A DK 326785A DK 167768 B1 DK167768 B1 DK 167768B1
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DK
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Prior art keywords
mono
acid
methanol
chlorine
compound
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DK326785A
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Danish (da)
English (en)
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DK326785A (da
DK326785D0 (da
Inventor
Jerry Charles Bommer
Bruce Franklin Burnham
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Nippon Petrochemicals Co Ltd
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Publication of DK326785A publication Critical patent/DK326785A/da
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/44—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0036—Porphyrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
    • A61K49/0052—Small organic molecules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795—Porphyrin- or corrin-ring-containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0819—Tripeptides with the first amino acid being acidic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1021—Tetrapeptides with the first amino acid being acidic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Pyrrole Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Rolls And Other Rotary Bodies (AREA)
DK326785A 1984-07-18 1985-07-18 Fluorescerende mono- eller polyamider af en aminodicarboxylsyre og en tetrapyrrolforbindelse indeholdende mindst en carboxylgruppe samt terapeutisk praeparat indeholdende disse forbindelser DK167768B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63192584 1984-07-18
US06/631,925 US4675338A (en) 1984-07-18 1984-07-18 Tetrapyrrole therapeutic agents

Publications (3)

Publication Number Publication Date
DK326785D0 DK326785D0 (da) 1985-07-18
DK326785A DK326785A (da) 1986-01-19
DK167768B1 true DK167768B1 (da) 1993-12-13

Family

ID=24533344

Family Applications (1)

Application Number Title Priority Date Filing Date
DK326785A DK167768B1 (da) 1984-07-18 1985-07-18 Fluorescerende mono- eller polyamider af en aminodicarboxylsyre og en tetrapyrrolforbindelse indeholdende mindst en carboxylgruppe samt terapeutisk praeparat indeholdende disse forbindelser

Country Status (11)

Country Link
US (1) US4675338A (de)
EP (1) EP0168832B1 (de)
JP (2) JPH0689000B2 (de)
AT (1) ATE94547T1 (de)
AU (1) AU579387B2 (de)
CA (1) CA1262862A (de)
DE (1) DE3587579T2 (de)
DK (1) DK167768B1 (de)
HK (1) HK135994A (de)
NO (1) NO169290C (de)
SG (1) SG103194G (de)

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Also Published As

Publication number Publication date
EP0168832A3 (en) 1988-05-04
AU579387B2 (en) 1988-11-24
JPH0688902B2 (ja) 1994-11-09
EP0168832B1 (de) 1993-09-15
DE3587579D1 (de) 1993-10-21
NO852871L (no) 1986-01-20
AU4515885A (en) 1986-03-27
US4675338A (en) 1987-06-23
NO169290B (no) 1992-02-24
DK326785A (da) 1986-01-19
ATE94547T1 (de) 1993-10-15
JPH0689000B2 (ja) 1994-11-09
JPS6183186A (ja) 1986-04-26
DK326785D0 (da) 1985-07-18
DE3587579T2 (de) 1994-02-17
SG103194G (en) 1994-10-28
EP0168832A2 (de) 1986-01-22
JPS61129163A (ja) 1986-06-17
HK135994A (en) 1994-12-09
CA1262862C (en) 1989-11-14
CA1262862A (en) 1989-11-14
NO169290C (no) 1992-06-03

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