DK168024B1 - Testmiddel og -materiale til visuel bestemmelse a f hydrogenperoxid - Google Patents

Testmiddel og -materiale til visuel bestemmelse a f hydrogenperoxid Download PDF

Info

Publication number: DK168024B1
Authority: DK; Denmark
Prior art keywords: indicator; hydrogen peroxide; oxidized; tint; oxidative
Prior art date: 1987-09-11

Application number

DK501388A

Other languages

Danish (da)

English (en)

Other versions

DK501388D0 (da

DK501388A (da

Inventor

Steven C Charlton

Elva Kurchacova

Original Assignee

Miles Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-09-11

Filing date

1988-09-09

Publication date

1994-01-17

1988-09-09 Application filed by Miles Inc filed Critical Miles Inc

1988-09-09 Publication of DK501388D0 publication Critical patent/DK501388D0/da

1989-03-12 Publication of DK501388A publication Critical patent/DK501388A/da

1994-01-17 Application granted granted Critical

1994-01-17 Publication of DK168024B1 publication Critical patent/DK168024B1/da

Links

MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 title claims abstract description 108
238000012360 testing method Methods 0.000 title claims abstract description 70
239000000463 material Substances 0.000 title claims description 19
230000000007 visual effect Effects 0.000 title claims description 17
230000001590 oxidative effect Effects 0.000 claims abstract description 36
239000012491 analyte Substances 0.000 claims abstract description 22
239000003795 chemical substances by application Substances 0.000 claims description 55
150000001875 compounds Chemical class 0.000 claims description 22
102000003992 Peroxidases Human genes 0.000 claims description 18
108040007629 peroxidase activity proteins Proteins 0.000 claims description 17
239000002253 acid Substances 0.000 claims description 15
230000008859 change Effects 0.000 claims description 14
239000007788 liquid Substances 0.000 claims description 14
239000002131 composite material Substances 0.000 claims description 13
102000004190 Enzymes Human genes 0.000 claims description 10
108090000790 Enzymes Proteins 0.000 claims description 10
BHNHHSOHWZKFOX-UHFFFAOYSA-N 2-methyl-1H-indole Chemical compound C1=CC=C2NC(C)=CC2=C1 BHNHHSOHWZKFOX-UHFFFAOYSA-N 0.000 claims description 9
239000013543 active substance Substances 0.000 claims description 9
-1 p-nitro-phenylazo Chemical group 0.000 claims description 9
239000011159 matrix material Substances 0.000 claims description 7
RLFWWDJHLFCNIJ-UHFFFAOYSA-N 4-aminoantipyrine Chemical compound CN1C(C)=C(N)C(=O)N1C1=CC=CC=C1 RLFWWDJHLFCNIJ-UHFFFAOYSA-N 0.000 claims description 6
239000000872 buffer Substances 0.000 claims description 5
LWKJNIMGNUTZOO-UHFFFAOYSA-M 3,5-dichloro-2-hydroxybenzenesulfonate Chemical compound OC1=C(Cl)C=C(Cl)C=C1S([O-])(=O)=O LWKJNIMGNUTZOO-UHFFFAOYSA-M 0.000 claims description 3
229910052739 hydrogen Inorganic materials 0.000 claims description 2
239000001257 hydrogen Substances 0.000 claims description 2
150000003839 salts Chemical class 0.000 claims description 2
125000004435 hydrogen atom Chemical class [H]* 0.000 claims 1
230000003647 oxidation Effects 0.000 abstract description 16
238000007254 oxidation reaction Methods 0.000 abstract description 16
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239000000203 mixture Substances 0.000 abstract description 6
235000019646 color tone Nutrition 0.000 description 20
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 17
239000008103 glucose Substances 0.000 description 17
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238000002360 preparation method Methods 0.000 description 12
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HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 8
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125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 6
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BPJYAXCTOHRFDQ-UHFFFAOYSA-L tetracopper;2,4,6-trioxido-1,3,5,2,4,6-trioxatriarsinane;diacetate Chemical compound [Cu+2].[Cu+2].[Cu+2].[Cu+2].CC([O-])=O.CC([O-])=O.[O-][As]1O[As]([O-])O[As]([O-])O1.[O-][As]1O[As]([O-])O[As]([O-])O1 BPJYAXCTOHRFDQ-UHFFFAOYSA-L 0.000 description 2
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ZYECOAILUNWEAL-NUDFZHEQSA-N (4z)-4-[[2-methoxy-5-(phenylcarbamoyl)phenyl]hydrazinylidene]-n-(3-nitrophenyl)-3-oxonaphthalene-2-carboxamide Chemical compound COC1=CC=C(C(=O)NC=2C=CC=CC=2)C=C1N\N=C(C1=CC=CC=C1C=1)/C(=O)C=1C(=O)NC1=CC=CC([N+]([O-])=O)=C1 ZYECOAILUNWEAL-NUDFZHEQSA-N 0.000 description 1
YQADLKDQAXAIKW-UHFFFAOYSA-N 2-amino-5-bromopyridin-3-ol Chemical compound NC1=NC=C(Br)C=C1O YQADLKDQAXAIKW-UHFFFAOYSA-N 0.000 description 1
UHGULLIUJBCTEF-UHFFFAOYSA-N 2-aminobenzothiazole Chemical compound C1=CC=C2SC(N)=NC2=C1 UHGULLIUJBCTEF-UHFFFAOYSA-N 0.000 description 1
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MNIQECRMTVGZBM-UHFFFAOYSA-N 3-(1-methylpyrrolidin-2-yl)pyridine;7h-purin-6-amine Chemical compound NC1=NC=NC2=C1NC=N2.CN1CCCC1C1=CC=CN=C1 MNIQECRMTVGZBM-UHFFFAOYSA-N 0.000 description 1
RZQXOGQSPBYUKH-UHFFFAOYSA-N 3-[[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]azaniumyl]-2-hydroxypropane-1-sulfonate Chemical compound OCC(CO)(CO)NCC(O)CS(O)(=O)=O RZQXOGQSPBYUKH-UHFFFAOYSA-N 0.000 description 1
CEOCHRYOARMIGS-UHFFFAOYSA-N 4,5-dichloro-2-hydroxybenzenesulfonic acid Chemical compound OC1=CC(Cl)=C(Cl)C=C1S(O)(=O)=O CEOCHRYOARMIGS-UHFFFAOYSA-N 0.000 description 1
QNGVNLMMEQUVQK-UHFFFAOYSA-N 4-n,4-n-diethylbenzene-1,4-diamine Chemical compound CCN(CC)C1=CC=C(N)C=C1 QNGVNLMMEQUVQK-UHFFFAOYSA-N 0.000 description 1
ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 description 1
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ROFVEXUMMXZLPA-UHFFFAOYSA-N Bipyridyl Chemical group N1=CC=CC=C1C1=CC=CC=N1 ROFVEXUMMXZLPA-UHFFFAOYSA-N 0.000 description 1
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RGHNJXZEOKUKBD-UHFFFAOYSA-N D-gluconic acid Natural products OCC(O)C(O)C(O)C(O)C(O)=O RGHNJXZEOKUKBD-UHFFFAOYSA-N 0.000 description 1
101100180051 Danio rerio isl2a gene Proteins 0.000 description 1
QXNVGIXVLWOKEQ-UHFFFAOYSA-N Disodium Chemical class [Na][Na] QXNVGIXVLWOKEQ-UHFFFAOYSA-N 0.000 description 1
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
CWYNVVGOOAEACU-UHFFFAOYSA-N Fe2+ Chemical compound [Fe+2] CWYNVVGOOAEACU-UHFFFAOYSA-N 0.000 description 1
BRDWIEOJOWJCLU-LTGWCKQJSA-N GS-441524 Chemical compound C=1C=C2C(N)=NC=NN2C=1[C@]1(C#N)O[C@H](CO)[C@@H](O)[C@H]1O BRDWIEOJOWJCLU-LTGWCKQJSA-N 0.000 description 1
RGHNJXZEOKUKBD-SQOUGZDYSA-N Gluconic acid Natural products OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O RGHNJXZEOKUKBD-SQOUGZDYSA-N 0.000 description 1
239000007995 HEPES buffer Substances 0.000 description 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 1
DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
FBWADIKARMIWNM-UHFFFAOYSA-N N-3,5-dichloro-4-hydroxyphenyl-1,4-benzoquinone imine Chemical compound C1=C(Cl)C(O)=C(Cl)C=C1N=C1C=CC(=O)C=C1 FBWADIKARMIWNM-UHFFFAOYSA-N 0.000 description 1
ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 1
239000004793 Polystyrene Substances 0.000 description 1
ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
101100126318 Rattus norvegicus Isl2 gene Proteins 0.000 description 1
229910006069 SO3H Inorganic materials 0.000 description 1
244000061456 Solanum tuberosum Species 0.000 description 1
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229920002253 Tannate Polymers 0.000 description 1
239000002250 absorbent Substances 0.000 description 1
230000002745 absorbent Effects 0.000 description 1
239000000370 acceptor Substances 0.000 description 1
125000000218 acetic acid group Chemical group C(C)(=O)* 0.000 description 1
ZXGIHDNEIWPDFW-UHFFFAOYSA-M acid red 4 Chemical compound [Na+].COC1=CC=CC=C1N=NC1=CC(S([O-])(=O)=O)=C(C=CC=C2)C2=C1O ZXGIHDNEIWPDFW-UHFFFAOYSA-M 0.000 description 1
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125000003277 amino group Chemical group 0.000 description 1
UKFWSNCTAHXBQN-UHFFFAOYSA-N ammonium iodide Chemical class [NH4+].[I-] UKFWSNCTAHXBQN-UHFFFAOYSA-N 0.000 description 1
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238000004458 analytical method Methods 0.000 description 1
WXLFIFHRGFOVCD-UHFFFAOYSA-L azophloxine Chemical compound [Na+].[Na+].OC1=C2C(NC(=O)C)=CC(S([O-])(=O)=O)=CC2=CC(S([O-])(=O)=O)=C1N=NC1=CC=CC=C1 WXLFIFHRGFOVCD-UHFFFAOYSA-L 0.000 description 1
WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
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125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 description 1
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DXTCFKRAUYBHRC-UHFFFAOYSA-L iron(2+);dithiocyanate Chemical compound [Fe+2].[S-]C#N.[S-]C#N DXTCFKRAUYBHRC-UHFFFAOYSA-L 0.000 description 1
230000002427 irreversible effect Effects 0.000 description 1
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125000001624 naphthyl group Chemical group 0.000 description 1
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125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 description 1
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UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 description 1
235000012739 red 2G Nutrition 0.000 description 1
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TVXXNOYZHKPKGW-UHFFFAOYSA-N sodium molybdate (anhydrous) Chemical compound [Na+].[Na+].[O-][Mo]([O-])(=O)=O TVXXNOYZHKPKGW-UHFFFAOYSA-N 0.000 description 1
STZCRXQWRGQSJD-UHFFFAOYSA-N sodium;4-[[4-(dimethylamino)phenyl]diazenyl]benzenesulfonic acid Chemical compound [Na+].C1=CC(N(C)C)=CC=C1N=NC1=CC=C(S(O)(=O)=O)C=C1 STZCRXQWRGQSJD-UHFFFAOYSA-N 0.000 description 1
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125000004079 stearyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
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Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
- C12Q1/28—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/54—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving glucose or galactose
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12Q2326/00—Chromogens for determinations of oxidoreductase enzymes
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2326/00—Chromogens for determinations of oxidoreductase enzymes
- C12Q2326/90—Developer
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Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
Investigating Or Analysing Biological Materials (AREA)
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DK501388A 1987-09-11 1988-09-09 Testmiddel og -materiale til visuel bestemmelse a f hydrogenperoxid DK168024B1 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US07/095,143 US4855228A (en)	1987-09-11	1987-09-11	Multiple oxidative indicator system for visual determination of hydrogen peroxide
US9514387		1987-09-11

Publications (3)

Publication Number	Publication Date
DK501388D0 DK501388D0 (da)	1988-09-09
DK501388A DK501388A (da)	1989-03-12
DK168024B1 true DK168024B1 (da)	1994-01-17

Family

ID=22250089

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK501388A DK168024B1 (da)	1987-09-11	1988-09-09	Testmiddel og -materiale til visuel bestemmelse a f hydrogenperoxid

Country Status (13)

Country	Link
US (1)	US4855228A (de)
EP (1)	EP0306803B1 (de)
JP (1)	JPH0690199B2 (de)
AT (1)	ATE96178T1 (de)
AU (1)	AU594254B2 (de)
CA (1)	CA1321535C (de)
DE (1)	DE3885048T2 (de)
DK (1)	DK168024B1 (de)
FI (1)	FI93277C (de)
IE (1)	IE61442B1 (de)
IL (1)	IL87438A (de)
NO (1)	NO172869C (de)
ZA (1)	ZA886281B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5436133A (en) *	1989-06-20	1995-07-25	Oriental Yeast Co., Ltd.	Enzyme assay of biochemical substances
JP2642527B2 (ja) *	1991-03-22	1997-08-20	淳一岩村	カタラーゼ活性測定法
JPH07155196A (ja) *	1993-12-10	1995-06-20	Dai Ichi Pure Chem Co Ltd	生体成分の測定法
US5702955A (en) *	1995-05-22	1997-12-30	Bayer Corporation	Ascorbate resistant detection of hydrogen peroxide
AU6852198A (en)	1997-04-17	1998-11-11	Fujimori Kogyo Co. Ltd.	Chemical indicator sheets and packaging bags for sterilization made with the useof the same
CN1318849C (zh)	1999-08-06	2007-05-30	Imi国际医学创新股份有限公司	以颜色为基础的生化和免疫分析中的光谱测量
US6790411B1 (en) *	1999-12-02	2004-09-14	3M Innovative Properties Company	Hydrogen peroxide indicator and method
US6635439B2 (en)	2000-12-21	2003-10-21	Ethicon, Inc.	Hydrogen peroxide indicator employing enzyme and dye
WO2014174818A1 (ja)	2013-04-26	2014-10-30	パナソニックＩｐマネジメント株式会社	酸化物質定量方法および酸化物質定量装置
EP3346836B1 (de) *	2015-09-10	2021-07-21	Ecolab USA Inc.	Selbstanzeigende antimikrobielle chemie
US11208675B2 (en)	2016-07-13	2021-12-28	Kikkoman Corporation	Reaction accelerating agent
US12613241B2 (en) *	2018-09-27	2026-04-28	Sekisui Medical Co., Ltd.	Immunochromatographic test strip

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2981606A (en) *	1955-06-20	1961-04-25	Lilly Co Eli	Glucose indicator and method
NL98884C (de) *	1957-01-08
US3008879A (en) *	1960-03-18	1961-11-14	Miles Lab	Diagnostic composition for the quantitative determination of glucose
US4132527A (en) *	1974-01-09	1979-01-02	Shionogi & Co., Ltd.	Diagnostic compositions, diagnosing instruments, and methods of manufacturing same
AT347600B (de) *	1974-11-11	1979-01-10	Wellcome Found	Testeinrichtungen
US4042329A (en) *	1974-12-18	1977-08-16	Becton, Dickinson And Company	Method and device for detecting cholesterol
JPS5645198A (en) *	1979-09-20	1981-04-24	Wako Pure Chem Ind Ltd	Determination of amount of hydrogen peroxide of activity of peroxidase
DE3211167A1 (de) *	1982-03-26	1983-09-29	Merck Patent Gmbh, 6100 Darmstadt	Testsystem und verfahren zur bestimmung von substanzen in fluessigkeiten
JPS59230161A (ja) *	1983-06-13	1984-12-24	Wako Pure Chem Ind Ltd	還元性物質の分解方法及び分解用試薬
US4810633A (en) *	1984-06-04	1989-03-07	Miles Inc.	Enzymatic ethanol test
JPS6152300A (ja) *	1984-08-22	1986-03-14	Eiken Kagaku Kk	過酸化水素測定用組成物
CA1295216C (en) *	1986-04-04	1992-02-04	James P. Albarella	Rainbow test device
US4898813A (en) *	1986-04-04	1990-02-06	Albarella James P	Catalytic test composition intended to produce a range of colors

1987
- 1987-09-11 US US07/095,143 patent/US4855228A/en not_active Expired - Lifetime
1988
- 1988-08-12 CA CA000574646A patent/CA1321535C/en not_active Expired - Fee Related
- 1988-08-12 IL IL87438A patent/IL87438A/xx not_active IP Right Cessation
- 1988-08-24 ZA ZA886281A patent/ZA886281B/xx unknown
- 1988-08-30 AT AT88114109T patent/ATE96178T1/de active
- 1988-08-30 NO NO883861A patent/NO172869C/no unknown
- 1988-08-30 EP EP88114109A patent/EP0306803B1/de not_active Expired - Lifetime
- 1988-08-30 DE DE88114109T patent/DE3885048T2/de not_active Expired - Fee Related
- 1988-09-07 AU AU21952/88A patent/AU594254B2/en not_active Ceased
- 1988-09-08 FI FI884131A patent/FI93277C/fi not_active IP Right Cessation
- 1988-09-09 JP JP63224884A patent/JPH0690199B2/ja not_active Expired - Lifetime
- 1988-09-09 DK DK501388A patent/DK168024B1/da not_active IP Right Cessation
- 1988-09-09 IE IE276388A patent/IE61442B1/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
DE3885048T2 (de)	1994-02-10
IL87438A (en)	1992-12-01
IE882763L (en)	1989-03-11
NO883861L (no)	1989-03-13
JPH01109261A (ja)	1989-04-26
EP0306803A3 (en)	1990-08-22
US4855228A (en)	1989-08-08
FI93277B (fi)	1994-11-30
DK501388D0 (da)	1988-09-09
FI93277C (fi)	1995-03-10
CA1321535C (en)	1993-08-24
AU2195288A (en)	1989-03-16
FI884131A0 (fi)	1988-09-08
NO172869B (no)	1993-06-07
DK501388A (da)	1989-03-12
DE3885048D1 (de)	1993-11-25
IE61442B1 (en)	1994-11-02
ZA886281B (en)	1989-05-30
ATE96178T1 (de)	1993-11-15
EP0306803A2 (de)	1989-03-15
FI884131L (fi)	1989-03-12
EP0306803B1 (de)	1993-10-20
NO172869C (no)	1993-09-15
NO883861D0 (no)	1988-08-30
IL87438A0 (en)	1989-01-31
AU594254B2 (en)	1990-03-01
JPH0690199B2 (ja)	1994-11-14

Legal Events

Date	Code	Title	Description
1994-01-17	B1	Patent granted (law 1993)
1996-05-20	PBP	Patent lapsed

Publication	Publication Date	Title
US3983005A (en)	1976-09-28	Integral element for the analysis of cholesterol
US4279993A (en)	1981-07-21	Indicator composition and test device containing amine oxide, and method of use
CA1339058C (en)	1997-07-29	Process and agent for the colorimetric determination of an analyte by means of enzymatic oxidation
US4089747A (en)	1978-05-16	Compositions for the detection of hydrogen peroxide
CA1225315A (en)	1987-08-11	Stabilized test composition, device and method for the determination of peroxidatively active substance
US4578245A (en)	1986-03-25	Multilayer analytical element
EP0102504A1 (de)	1984-03-14	Für einen breiten Bereich geeignete, ascorbat-unempfindliche Zusammensetzung zur Prüfung auf Glucose, Prüfmittel und Methode
PL114343B1 (en)	1981-01-31	Preparation for determining enzymatic substrates or enzyme activity
DK159171B (da)	1990-09-10	Materiale til detektering af naervaerelsen af et peroxidativt aktivt stof i en testproeve, testmiddel indeholdende materialet samt fremgangsmaade til fremstilling af testmidlet.
USRE32016E (en)	1985-10-29	Analysis of lactic acid or lactate using lactate oxidase
EP0020788B1 (de)	1983-07-13	Testprobe zum messen von glukose
JPH0464592B2 (de)	1992-10-15
CA1100021A (en)	1981-04-28	Test means and method for interference resistant determination of oxidizing substances
CA1095818A (en)	1981-02-17	Compositions, elements and method for the quantitative analysis of lactic or lactate using lactate oxidase
US4855228A (en)	1989-08-08	Multiple oxidative indicator system for visual determination of hydrogen peroxide
AU592440B2 (en)	1990-01-11	New derivatives as redox indicators, and the use thereof
EP0029926B1 (de)	1983-11-23	Einen Indikator des Benzidin-Typs enthaltende Zusammensetzung und Testgerät zum Nachweis eines Bestandteils in einer Probe
CA1056282A (en)	1979-06-12	Multilayer analytical elements for use in the assay of cholesterol
EP0036563A1 (de)	1981-09-30	Bilirubinbeständige Zusammensetzung zur Bestimmung von Cholesterin, diese Zusammensetzung enthaltende Probevorrichtung und Verfahren zur Herstellung dieser Probevorrichtung
EP0101945B1 (de)	1986-08-27	Mehrschichtiges analytisches Element
US5589347A (en)	1996-12-31	Multilayer analysis elements for the determination of total cholesterol
JPS6259782B2 (de)	1987-12-12
US4894472A (en)	1990-01-16	Dicyanoethylaryl derivatives and process for their preparation
CA1289443C (en)	1991-09-24	Test aids and method for the preparation thereof
EP0272578A2 (de)	1988-06-29	Mehrschichtige analytische Elemente zur Bestimmung von Gesamtcholesterin