DK1697752T3 - Assaychip og anvendelser af assaychippen til bestemmelse af molekyl- strukturer og -funktioner - Google Patents
Assaychip og anvendelser af assaychippen til bestemmelse af molekyl- strukturer og -funktionerInfo
- Publication number
- DK1697752T3 DK1697752T3 DK04820800T DK04820800T DK1697752T3 DK 1697752 T3 DK1697752 T3 DK 1697752T3 DK 04820800 T DK04820800 T DK 04820800T DK 04820800 T DK04820800 T DK 04820800T DK 1697752 T3 DK1697752 T3 DK 1697752T3
- Authority
- DK
- Denmark
- Prior art keywords
- nanopores
- assay chip
- layer
- support layer
- membrane
- Prior art date
Links
- 238000003556 assay Methods 0.000 title abstract 3
- 239000000232 Lipid Bilayer Substances 0.000 abstract 2
- 108010052285 Membrane Proteins Proteins 0.000 abstract 2
- 239000012528 membrane Substances 0.000 abstract 2
- 239000000758 substrate Substances 0.000 abstract 2
- 238000003384 imaging method Methods 0.000 abstract 1
- 230000003993 interaction Effects 0.000 abstract 1
- 238000011835 investigation Methods 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- 238000005259 measurement Methods 0.000 abstract 1
- 230000002459 sustained effect Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- Nanotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Crystallography & Structural Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Medical Informatics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03029726 | 2003-12-23 | ||
| EP04002119A EP1548444A1 (de) | 2003-12-23 | 2004-01-31 | Vorrichtung (Assay Chip) und Verfahren zur Bestimmung von Molekularen Strukturen und Funktionen |
| PCT/EP2004/012925 WO2005064342A1 (en) | 2003-12-23 | 2004-11-15 | An assay chip, and uses of said assay chip to determine molecular structures and functions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1697752T3 true DK1697752T3 (da) | 2008-08-11 |
Family
ID=34553646
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK04820800T DK1697752T3 (da) | 2003-12-23 | 2004-11-15 | Assaychip og anvendelser af assaychippen til bestemmelse af molekyl- strukturer og -funktioner |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US8105820B2 (de) |
| EP (2) | EP1548444A1 (de) |
| JP (1) | JP4448142B2 (de) |
| CN (1) | CN1902497B (de) |
| AT (1) | ATE391916T1 (de) |
| DE (1) | DE602004013042T2 (de) |
| DK (1) | DK1697752T3 (de) |
| WO (1) | WO2005064342A1 (de) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7857978B2 (en) * | 2005-05-20 | 2010-12-28 | Aquaporin A/S | Membrane for filtering of water |
| KR100840619B1 (ko) | 2006-12-19 | 2008-06-24 | 한양대학교 산학협력단 | 표면개질된 리포좀, 이를 포함하는 바이오칩 및 그제조방법 |
| GB0724736D0 (en) | 2007-12-19 | 2008-01-30 | Oxford Nanolabs Ltd | Formation of layers of amphiphilic molecules |
| WO2013154750A1 (en) * | 2012-04-10 | 2013-10-17 | The Trustees Of Columbia Unversity In The City Of New York | Systems and methods for biological ion channel interfaces |
| JP5687683B2 (ja) * | 2009-03-26 | 2015-03-18 | トラスティーズ オブ ボストン ユニバーシティ | ２種類の流体間の薄い固相界面上における撮像方法 |
| EP2288917A1 (de) * | 2009-07-07 | 2011-03-02 | Leister Process Technologies | Chip zur bestimmung von molekülstrukturen und -funktionen |
| JP5325735B2 (ja) * | 2009-10-05 | 2013-10-23 | エスケー化研株式会社 | 塗膜形成方法 |
| AU2011218847B2 (en) | 2010-02-23 | 2015-03-12 | Christopher Gordon Atwood | Methods for the detection of biologically relevant molecules and their interaction characteristics |
| EP2474829A1 (de) | 2011-01-07 | 2012-07-11 | Axetris AG | Verfahren zur Bestimmung von Molekülstrukturen und Funktionen |
| CN103380369B (zh) | 2011-02-23 | 2016-12-28 | 纽约市哥伦比亚大学理事会 | 使用纳米孔进行单分子检测的系统和方法 |
| WO2012146458A2 (en) | 2011-04-26 | 2012-11-01 | Paul Scherrer Institut | A method for producing a polymer-based microfluidics system for bioanalytics using biological membranes |
| GB201202519D0 (en) * | 2012-02-13 | 2012-03-28 | Oxford Nanopore Tech Ltd | Apparatus for supporting an array of layers of amphiphilic molecules and method of forming an array of layers of amphiphilic molecules |
| KR101569891B1 (ko) * | 2012-02-13 | 2015-11-27 | 동국대학교 산학협력단 | 다공성 지지체를 이용한 저분자 포집용 졸-겔 칩 및 이를 이용한 저분자 특이적 물질의 스크리닝 방법 |
| GB201313121D0 (en) | 2013-07-23 | 2013-09-04 | Oxford Nanopore Tech Ltd | Array of volumes of polar medium |
| GB201300465D0 (en) | 2013-01-11 | 2013-02-27 | Aquaporin As | A hollow fiber module having tfc-aquaporin modified membranes |
| DK177696B1 (en) | 2013-02-25 | 2014-03-17 | Aquaporin As | Systems for water extraction |
| CN103592433A (zh) * | 2013-11-29 | 2014-02-19 | 南京祥中生物科技有限公司 | 一种生物芯片微阵列布点方法 |
| CN103940864B (zh) * | 2014-03-25 | 2016-03-09 | 西北大学 | 双管式单分子微流装置 |
| CN106573220B (zh) * | 2014-07-24 | 2019-08-16 | 凸版印刷株式会社 | 脂质膜结构体、脂质膜结构体固定化载体、及胞体的融合方法 |
| GB201611770D0 (en) | 2016-07-06 | 2016-08-17 | Oxford Nanopore Tech | Microfluidic device |
| WO2018217419A1 (en) * | 2017-05-26 | 2018-11-29 | Quantapore, Inc. | Stable lipid bilayers on nanopore arrays |
| WO2019008736A1 (ja) * | 2017-07-07 | 2019-01-10 | 株式会社日立ハイテクノロジーズ | 薄膜デバイス保管装置，保管方法及び生体分子計測方法 |
| CN109709185B (zh) * | 2017-10-25 | 2024-09-24 | 深圳宣泽生物医药有限公司 | 一种修饰生物探针的纳米孔检测装置及制作方法 |
| GB2568895B (en) | 2017-11-29 | 2021-10-27 | Oxford Nanopore Tech Ltd | Microfluidic device |
| GB2574048B (en) | 2018-05-24 | 2021-06-16 | Oxford Nanopore Tech Ltd | Nanopore sensor component with electrostatic discharge protection |
| JP7492200B2 (ja) | 2019-03-12 | 2024-05-29 | オックスフォード ナノポール テクノロジーズ ピーエルシー | ナノ細孔センシングデバイスと操作方法およびその成形方法 |
| EP3977137B1 (de) * | 2019-05-29 | 2026-04-01 | Nanjing University | Nachweis von analyten durch nanopore ohne verwendung von elektroden |
| EP4675256A3 (de) | 2020-07-17 | 2026-01-28 | Oxford Nanopore Technologies PLC | Nanoporenmessvorrichtung |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1157743T3 (da) * | 1993-10-28 | 2009-07-06 | Houston Advanced Res Ct | Mikrofremstillet poröst gennemströmningsapparat til diskret påvisning af bindingsreaktioner |
| US5716526A (en) * | 1994-01-14 | 1998-02-10 | The Liposome Company, Inc. | Method of separating materials from liposomes or lipid complexes |
| WO2000034527A2 (en) * | 1998-12-11 | 2000-06-15 | The Regents Of The University Of California | Targeted molecular bar codes |
| US6783643B2 (en) * | 1999-06-22 | 2004-08-31 | President And Fellows Of Harvard College | Control of solid state dimensional features |
| EP2083015B1 (de) * | 2000-02-11 | 2016-04-06 | The Texas A & M University System | Biosensorzusammensetzungen und Verfahren zu ihrer Verwendung |
| AU2001296809A1 (en) * | 2000-10-10 | 2002-04-22 | Biotrove, Inc. | Apparatus for assay, synthesis and storage, and methods of manufacture, use, and manipulation thereof |
| US6818907B2 (en) * | 2000-10-17 | 2004-11-16 | The President And Fellows Of Harvard College | Surface plasmon enhanced illumination system |
| JP2002218974A (ja) * | 2001-01-24 | 2002-08-06 | Ebara Corp | 反応プローブチップ及び検出システム |
| WO2003016040A1 (en) * | 2001-04-16 | 2003-02-27 | The Regents Of The University Of California | Membrane mimetic architectures on nanoporous materials |
| US6785432B2 (en) * | 2001-06-15 | 2004-08-31 | The Regents Of The University Of California | Target molecules detection by waveguiding in a photonic silicon membrane |
| DE10142691B4 (de) * | 2001-08-31 | 2006-04-20 | Infineon Technologies Ag | Verfahren zum Nachweis biochemischer Reaktionen sowie eine Vorrichtung hierfür |
| US6875671B2 (en) * | 2001-09-12 | 2005-04-05 | Reveo, Inc. | Method of fabricating vertical integrated circuits |
| US20050230272A1 (en) * | 2001-10-03 | 2005-10-20 | Lee Gil U | Porous biosensing device |
| US20030104512A1 (en) * | 2001-11-30 | 2003-06-05 | Freeman Alex R. | Biosensors for single cell and multi cell analysis |
| US20040120854A1 (en) * | 2002-04-04 | 2004-06-24 | Heath James R | Silicon-wafer based devices and methods for analyzing biological material |
| US7744816B2 (en) * | 2002-05-01 | 2010-06-29 | Intel Corporation | Methods and device for biomolecule characterization |
-
2004
- 2004-01-31 EP EP04002119A patent/EP1548444A1/de not_active Withdrawn
- 2004-11-15 DK DK04820800T patent/DK1697752T3/da active
- 2004-11-15 EP EP04820800A patent/EP1697752B1/de not_active Expired - Lifetime
- 2004-11-15 CN CN2004800385672A patent/CN1902497B/zh not_active Expired - Lifetime
- 2004-11-15 DE DE602004013042T patent/DE602004013042T2/de not_active Expired - Lifetime
- 2004-11-15 JP JP2006545940A patent/JP4448142B2/ja not_active Expired - Lifetime
- 2004-11-15 US US10/584,484 patent/US8105820B2/en active Active
- 2004-11-15 WO PCT/EP2004/012925 patent/WO2005064342A1/en not_active Ceased
- 2004-11-15 AT AT04820800T patent/ATE391916T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1697752B1 (de) | 2008-04-09 |
| EP1697752A1 (de) | 2006-09-06 |
| JP2007529003A (ja) | 2007-10-18 |
| US8105820B2 (en) | 2012-01-31 |
| JP4448142B2 (ja) | 2010-04-07 |
| CN1902497B (zh) | 2012-08-22 |
| DE602004013042T2 (de) | 2009-05-14 |
| WO2005064342A1 (en) | 2005-07-14 |
| DE602004013042D1 (de) | 2008-05-21 |
| US20070275480A1 (en) | 2007-11-29 |
| EP1548444A1 (de) | 2005-06-29 |
| CN1902497A (zh) | 2007-01-24 |
| ATE391916T1 (de) | 2008-04-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE391916T1 (de) | Testchip sowie verwendungen des testchips zur bestimmung molekularer strukturen und funktionen | |
| Funakoshi et al. | Lipid bilayer formation by contacting monolayers in a microfluidic device for membrane protein analysis | |
| Su et al. | Surface plasmon resonance spectroscopy and quartz crystal microbalance study of streptavidin film structure effects on biotinylated DNA assembly and target DNA hybridization | |
| ES2412887T3 (es) | Sensor piezoeléctrico en voladizo de autodetección, autoexcitable | |
| Römer et al. | Channel activity of a viral transmembrane peptide in micro-BLMs: Vpu1-32 from HIV-1 | |
| SE0403139D0 (sv) | Device and use thereof | |
| DE60225058D1 (de) | Teststreifen zur bestimmung von triglyceridkonzentrationen | |
| CA2951945C (en) | Apparatuses and methods for determining analyte charge | |
| SE0100875D0 (sv) | Method of preparing supported lipid film membranes and use thereof | |
| WO2003068947A8 (en) | Assay electrodes having immobilized lipid/protein layers and methods of making and using the same | |
| EP2154522A3 (de) | Biosensor | |
| EP1390730A4 (de) | Integrierter dünnfilm-flüssigkeitsleitfähigkeitsensor | |
| ATE527543T1 (de) | Testvorrichtung zur schnelldiagnose | |
| EA200601753A1 (ru) | Синтетические "мембранные якори" | |
| Anna et al. | Methods for 20S immunoproteasome and 20S constitutive proteasome determination based on SPRI biosensors | |
| Chen et al. | Target-protecting dumbbell molecular probe against exonucleases digestion for sensitive detection of ATP and streptavidin | |
| ATE389177T1 (de) | Immobilisierung von bindungsstoffen | |
| BRPI0416270A (pt) | método para detectar um analito em uma amostra, e, método e kit para detectar um anticorpo especìfico de uma amostra | |
| Suzuki et al. | Ninety-six-well planar lipid bilayer chip for ion channel recording fabricated by hybrid stereolithography | |
| Sikanen et al. | Hybrid ceramic polymers: New, nonbiofouling, and optically transparent materials for microfluidics | |
| CN117897501A (zh) | 纳米力学可致动核酸纳米孔 | |
| ATE367577T1 (de) | Optischer biosensor | |
| DE60328359D1 (de) | Für den chemilumineszenznachweis optimierte festphasen | |
| DE60138610D1 (de) | Teststreifen mit poröser Filterschicht | |
| NO20080908L (no) | Stasjonaer stotteseng til rensing, separering, pavising, modifisering og/eller immoblisering av malenheter og fremgangsmater for anvedelse derav |