DK1713458T5 - Fremgangsmåde til forstærkning af biotilgængeligheden af ospemifen - Google Patents

Fremgangsmåde til forstærkning af biotilgængeligheden af ospemifen

Info

Publication number: DK1713458T5
Authority: DK; Denmark
Prior art keywords: bioavailability; enhancing; ospemifene; compound; stereoisomer
Prior art date: 2004-02-13

Application number

DK05701734T

Other languages

Danish (da)

English (en)

Other versions

DK1713458T3 (da

Inventor

Markku Anttila

Original Assignee

Hormos Medical Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-02-13

Filing date

2005-01-14

Publication date

2008-09-29

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34837941&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1713458(T5) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2005-01-14 Application filed by Hormos Medical Ltd filed Critical Hormos Medical Ltd

2008-07-07 Application granted granted Critical

2008-07-07 Publication of DK1713458T3 publication Critical patent/DK1713458T3/da

2008-09-29 Publication of DK1713458T5 publication Critical patent/DK1713458T5/da

Links

230000002708 enhancing effect Effects 0.000 title abstract 2
LUMKNAVTFCDUIE-VHXPQNKSSA-N ospemifene Chemical compound C1=CC(OCCO)=CC=C1C(\C=1C=CC=CC=1)=C(\CCCl)C1=CC=CC=C1 LUMKNAVTFCDUIE-VHXPQNKSSA-N 0.000 title 1
229960003969 ospemifene Drugs 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 2
150000002148 esters Chemical class 0.000 abstract 1
239000002207 metabolite Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/075—Ethers or acetals
- A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/30—Dietetic or nutritional methods, e.g. for losing weight
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/075—Ethers or acetals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Nutrition Science (AREA)
Physical Education & Sports Medicine (AREA)
Endocrinology (AREA)
Food Science & Technology (AREA)
Polymers & Plastics (AREA)
Mycology (AREA)
Rheumatology (AREA)
Reproductive Health (AREA)
Orthopedic Medicine & Surgery (AREA)
Physiology (AREA)
Diabetes (AREA)
Dermatology (AREA)
Urology & Nephrology (AREA)
Gynecology & Obstetrics (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Hydrogenated Pyridines (AREA)
Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)

DK05701734T 2004-02-13 2005-01-14 Fremgangsmåde til forstærkning af biotilgængeligheden af ospemifen DK1713458T5 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US10/777,211 US8236861B2 (en)	2004-02-13	2004-02-13	Method for enhancing the bioavailablity of ospemifene
PCT/FI2005/000018 WO2005077350A1 (en)	2004-02-13	2005-01-14	Method for enhancing the bioavailability of ospemifene

Publications (2)

Publication Number	Publication Date
DK1713458T3 DK1713458T3 (da)	2008-07-07
DK1713458T5 true DK1713458T5 (da)	2008-09-29

Family

ID=34837941

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK05701734T DK1713458T5 (da)	2004-02-13	2005-01-14	Fremgangsmåde til forstærkning af biotilgængeligheden af ospemifen

Country Status (23)

Country	Link
US (5)	US8236861B2 (2)
EP (1)	EP1713458B1 (2)
JP (2)	JP5577011B2 (2)
CN (1)	CN1925847A (2)
AT (1)	ATE387910T1 (2)
AU (1)	AU2005211958B2 (2)
BE (1)	BE2015C033I2 (2)
BR (1)	BRPI0507661A (2)
CA (1)	CA2556089C (2)
CY (2)	CY1111014T1 (2)
DE (1)	DE602005005165T2 (2)
DK (1)	DK1713458T5 (2)
ES (1)	ES2302177T3 (2)
FR (1)	FR15C0041I2 (2)
HU (1)	HUS1500030I1 (2)
LT (1)	LTC1713458I2 (2)
LU (1)	LU92736I2 (2)
MX (1)	MXPA06009274A (2)
NO (2)	NO337656B1 (2)
PL (1)	PL1713458T3 (2)
PT (1)	PT1713458E (2)
RU (1)	RU2385716C2 (2)
WO (1)	WO2005077350A1 (2)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US8236861B2 (en)	2004-02-13	2012-08-07	Hormos Medical Corporation	Method for enhancing the bioavailablity of ospemifene
US8642079B2 (en) *	2004-02-23	2014-02-04	Hormos Medical Corporation	Solid formulations of ospemifene
US8758821B2 (en) *	2004-05-04	2014-06-24	Hormos Medical Ltd.	Oral formulations of ospemifene
DK1742618T3 (da)	2004-05-04	2012-10-01	Hormos Medical Ltd	Flydende orale formuleringer af ospemifen
CN101304738A (zh) *	2005-11-09	2008-11-12	霍尔莫斯医疗有限公司	非培米芬的制剂
US8637706B2 (en)	2005-11-28	2014-01-28	Gtx, Inc.	Nuclear receptor binding agents
US8546451B2 (en) *	2005-11-28	2013-10-01	Gtx, Inc.	Estrogen receptor ligands and methods of use thereof
US8158828B2 (en) *	2005-11-28	2012-04-17	Gtx, Inc.	Nuclear receptor binding agents
US9409856B2 (en)	2005-11-28	2016-08-09	Gtx, Inc.	Estrogen receptor ligands and methods of use thereof
EA201500845A1 (ru) *	2005-11-28	2016-04-29	Джи Ти Икс, ИНК.	Агенты, связывающиеся с ядерными рецепторами
US7504530B2 (en) *	2007-02-14	2009-03-17	Hormos Medical Ltd.	Methods for the preparation of fispemifene from ospemifene
CA2677861C (en) *	2007-02-14	2015-05-19	Hormos Medical Ltd.	Method for the preparation of therapeutically valuable triphenylbutene derivatives
US9624161B2 (en)	2009-02-23	2017-04-18	Gtx, Inc.	Estrogen receptor ligands and methods of use thereof
US9427418B2 (en)	2009-02-23	2016-08-30	Gtx, Inc.	Estrogen receptor ligands and methods of use thereof
WO2014060639A1 (en)	2012-10-19	2014-04-24	Fermion Oy	A process for the preparation of ospemifene
CN103739456A (zh) *	2013-12-03	2014-04-23	镇江圣安医药有限公司	2-（对-（（z-4-氯-1,2-二苯基-1-丁烯基）苯氧基）乙醇的新型衍生物及其应用
GR1009542B (el)	2018-04-25	2019-06-07	Φαρματεν Α.Β.Ε.Ε.	Καψουλα μαλακης γελης που περιλαμβανει εναν εκλεκτικο ρυθμιστη οιστρογονικων υποδοχεων
FI3790548T3 (fi)	2018-05-11	2023-11-17	Xenon Pharmaceuticals Inc	Menetelmiä jänniteriippuvaisen kaliumkanavan avaajan biosaatavuuden ja eksposition tehostamiseksi
TWI886158B (zh)	2019-10-10	2025-06-11	加拿大商再諾製藥公司	選擇性鉀通道調節劑之固態晶型
WO2021092439A1 (en)	2019-11-08	2021-05-14	Xenon Pharmaceuticals Inc.	Methods of treating depressive disorders
IL304920A (en)	2021-02-09	2023-10-01	Xenon Pharmaceuticals Inc	A voltage-gated potassium channel opener for use in the treatment of anhedonia

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9007052D0 (en) *	1990-03-29	1990-05-30	Skua Investments Ltd	Pharmaceutical formulations
GB9207437D0 (en)	1992-04-03	1992-05-20	Orion Yhtymae Oy	Topical administration of toremifene and its metabolites
GB9418067D0 (en)	1994-09-07	1994-10-26	Orion Yhtymae Oy	Triphenylethylenes for the prevention and treatment of osteoporosis
GB9604577D0 (en)	1996-03-04	1996-05-01	Orion Yhtymae Oy	Serum cholesterol lowering agent
EP1102755B1 (en) *	1998-08-07	2006-01-04	Chiron Corporation	Substituted isoxazole derivatives as estrogen receptor modulators
US6219674B1 (en)	1999-11-24	2001-04-17	Classen Immunotherapies, Inc.	System for creating and managing proprietary product data
US6245819B1 (en) *	2000-07-21	2001-06-12	Hormos Medical Oy, Ltd.	Method for the treatment of vaginal dryness and sexual dysfunction in women during or after the menopause
US6653639B1 (en) *	2000-10-17	2003-11-25	Nikon Corporation	Chuck for mounting reticle to a reticle stage
WO2002069254A2 (en)	2001-02-22	2002-09-06	Classen Immunotherapies, Inc.	Improved algorithms and methods for products safety
FR2826811B1 (fr)	2001-06-27	2003-11-07	France Telecom	Procede d'authentification cryptographique
SI1509215T1 (sl)	2002-06-06	2007-02-28	Hormos Medical Ltd	Zdravljenje ali preprecevanje urogenitalne atrofije in njenih simptomov pri zenskah
US8236861B2 (en) *	2004-02-13	2012-08-07	Hormos Medical Corporation	Method for enhancing the bioavailablity of ospemifene
US8642079B2 (en)	2004-02-23	2014-02-04	Hormos Medical Corporation	Solid formulations of ospemifene
US20050187302A1 (en)	2004-02-23	2005-08-25	Hormos Medical Corporation	Method for treatment or prevention of osteoporosis in individuals with high bone turnover
US8758821B2 (en)	2004-05-04	2014-06-24	Hormos Medical Ltd.	Oral formulations of ospemifene
US20060293294A1 (en)	2004-09-03	2006-12-28	Hormos Medical Corporation	Method for treatment or prevention of androgen deficiency
KR100665758B1 (ko) *	2005-09-15	2007-01-09	제일모직주식회사	반사방지성을 갖는 하드마스크 조성물

2004
- 2004-02-13 US US10/777,211 patent/US8236861B2/en active Active
2005
- 2005-01-14 WO PCT/FI2005/000018 patent/WO2005077350A1/en not_active Ceased
- 2005-01-14 AU AU2005211958A patent/AU2005211958B2/en not_active Ceased
- 2005-01-14 BR BRPI0507661-7A patent/BRPI0507661A/pt not_active Application Discontinuation
- 2005-01-14 PT PT05701734T patent/PT1713458E/pt unknown
- 2005-01-14 JP JP2006552639A patent/JP5577011B2/ja not_active Expired - Fee Related
- 2005-01-14 DE DE602005005165T patent/DE602005005165T2/de not_active Expired - Lifetime
- 2005-01-14 AT AT05701734T patent/ATE387910T1/de active
- 2005-01-14 DK DK05701734T patent/DK1713458T5/da active
- 2005-01-14 EP EP05701734A patent/EP1713458B1/en not_active Expired - Lifetime
- 2005-01-14 CN CNA200580004550XA patent/CN1925847A/zh active Pending
- 2005-01-14 MX MXPA06009274A patent/MXPA06009274A/es active IP Right Grant
- 2005-01-14 PL PL05701734T patent/PL1713458T3/pl unknown
- 2005-01-14 CA CA2556089A patent/CA2556089C/en not_active Expired - Lifetime
- 2005-01-14 ES ES05701734T patent/ES2302177T3/es not_active Expired - Lifetime
- 2005-01-14 RU RU2006132719/15A patent/RU2385716C2/ru active
2006
- 2006-09-05 NO NO20063960A patent/NO337656B1/no unknown
2008
- 2008-04-24 CY CY20081100456T patent/CY1111014T1/el unknown
2012
- 2012-07-06 US US13/543,166 patent/US8470890B2/en not_active Expired - Fee Related
2013
- 2013-05-29 US US13/904,818 patent/US8772353B2/en not_active Expired - Lifetime
2014
- 2014-05-12 JP JP2014098549A patent/JP6023119B2/ja not_active Expired - Fee Related
- 2014-06-20 US US14/310,822 patent/US9241915B2/en not_active Expired - Fee Related
2015
- 2015-06-10 LU LU92736C patent/LU92736I2/xx unknown
- 2015-06-10 BE BE2015C033C patent/BE2015C033I2/fr unknown
- 2015-06-11 FR FR15C0041C patent/FR15C0041I2/fr active Active
- 2015-06-16 HU HUS1500030C patent/HUS1500030I1/hu unknown
- 2015-06-25 LT LTPA2015023C patent/LTC1713458I2/lt unknown
- 2015-07-08 CY CY2015027C patent/CY2015027I1/el unknown
- 2015-11-25 NO NO20151603A patent/NO339190B1/no unknown
- 2015-12-16 US US14/971,252 patent/US9855224B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
FR15C0041I1 (2)	2015-07-17
DE602005005165D1 (de)	2008-04-17
JP5577011B2 (ja)	2014-08-20
US20050182143A1 (en)	2005-08-18
US8470890B2 (en)	2013-06-25
HUS1500030I1 (hu)	2015-08-28
CA2556089C (en)	2013-04-02
ATE387910T1 (de)	2008-03-15
BRPI0507661A (pt)	2007-07-17
PT1713458E (pt)	2008-05-07
AU2005211958A1 (en)	2005-08-25
NO20151603L (no)	2006-11-03
LU92736I2 (fr)	2015-08-10
US20140303259A1 (en)	2014-10-09
US20130324614A1 (en)	2013-12-05
CY2015027I2 (el)	2016-04-13
US20120270952A1 (en)	2012-10-25
CY2015027I1 (el)	2016-04-13
EP1713458B1 (en)	2008-03-05
CA2556089A1 (en)	2005-08-25
LTPA2015023I1 (lt)	2015-08-25
LTC1713458I2 (lt)	2017-06-26
AU2005211958B2 (en)	2010-11-25
WO2005077350A1 (en)	2005-08-25
CY1111014T1 (el)	2015-06-11
DK1713458T3 (da)	2008-07-07
US8236861B2 (en)	2012-08-07
RU2385716C2 (ru)	2010-04-10
PL1713458T3 (pl)	2008-08-29
ES2302177T3 (es)	2008-07-01
BE2015C033I2 (2)	2024-08-08
MXPA06009274A (es)	2007-04-16
US8772353B2 (en)	2014-07-08
JP2007522190A (ja)	2007-08-09
US9241915B2 (en)	2016-01-26
FR15C0041I2 (fr)	2015-11-13
DE602005005165T2 (de)	2009-04-30
JP6023119B2 (ja)	2016-11-09
US9855224B2 (en)	2018-01-02
NO337656B1 (no)	2016-05-23
NO339190B1 (no)	2016-11-14
US20160101065A1 (en)	2016-04-14
CN1925847A (zh)	2007-03-07
JP2014141533A (ja)	2014-08-07
RU2006132719A (ru)	2008-03-20
NO20063960L (no)	2006-11-03
EP1713458A1 (en)	2006-10-25

Publication	Publication Date	Title
HUS1500030I1 (hu)	2015-08-28	Eljárás az ospemifene biohasznosulásának javítására
CY1111689T1 (el)	2015-10-07	Στερεες φαρμακοτεχνικες μορφες ospemifene
AR107474A2 (es)	2018-05-02	Proceso para la preparación de un ácido de 1,2,4-oxadiazol benzoico
WO2009066326A3 (en)	2009-07-30	Improved process for the preparation of prasugrel and its pharmaceutically acceptable salts
EA201100795A1 (ru)	2012-01-30	Фармацевтическая композиция эффективного ингибитора всг для перорального введения
MX2009003739A (es)	2009-09-04	Derivados de hidrobenzamida como inhibidores de hsp90.
EA200901563A1 (ru)	2010-06-30	Новый способ синтеза ивабрадина и его солей присоединения с фармацевтически приемлемой кислотой
ATE433988T1 (de)	2009-07-15	Phosphoramidatderivate
EA200800147A1 (ru)	2008-06-30	Способ получения олмесартан медоксомила
AR051754A1 (es)	2007-02-07	Metodos para preparar compuestos de indazol
EA201100994A1 (ru)	2012-03-30	Способ получения производных бисфуранового спирта, соединения, соль, фармацевтическая композиция на ее основе, способ лечения или профилактики ретровирусных инфекций с ее помощью
EA200970449A1 (ru)	2009-08-28	Композиции ацетаминофена, обладающие сведенными к минимуму побочными эффектами, включая пониженную гепатотоксичность
FR2983409B1 (fr)	2013-12-27	Comprime susceptible de lutter contre le detournement par voie injectable
DK1678162T3 (da)	2010-08-02	P-glycoprotein-inhibitor, fremgangsmåde til fremstilling heraf og farmaceutisk sammensætning omfattende denne
NO20082181L (no)	2008-05-27	Formuleringer av Fispemifen
UA97348C2 (en)	2012-02-10	HETEROCYCLIC NF-kB INHIBITORS
WO2009011901A3 (en)	2009-03-26	Methods for promoting wakefulness
DK1791537T3 (da)	2010-03-01	3-arylthioindol-2-carboxamidderivater og analoger deraf som inhibitorer af casein-kinase
CR10506A (es)	2009-02-02	Derivados de acido fenilacetico
BRPI0512251A (pt)	2008-02-19	método enantioseletivo para separação de derivados do ácido 2-trifluormetil-2h-cromeno-3-carboxìlico substituìdo
WO2007133476A3 (en)	2007-12-27	Competitive substrate inhibition to increase drug bioavailability
EA200901085A1 (ru)	2010-02-26	Производные циклогексиламида арилкарбоновой кислоты
AP2277A (en)	2011-10-31	Process for production of 1,2,2,2-tertafluoro ethyl difluoro methyl ether.
DE602006014001D1 (de)	2010-06-10	Herstellung von 2-aminothiazol-5-carbonsäurederivaten
RU2004116385A (ru)	2005-11-10	Средство для коррекции уролого-андрологической патологии