DK1718322T3 - Synergistiske sammensætninger med FK-228 - Google Patents

Synergistiske sammensætninger med FK-228

Info

Publication number: DK1718322T3
Authority: DK; Denmark
Prior art keywords: antitumor agent; antitumor; synergistic compositions; agent; dna
Prior art date: 2004-02-25

Application number

DK05719967.1T

Other languages

English (en)

Inventor

Takeshi Inoue

Yoshinori Naoe

Yasuhiko Kano

Original Assignee

Astellas Pharma Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-02-25

Filing date

2005-02-25

Publication date

2011-08-29

2005-02-25 Application filed by Astellas Pharma Inc filed Critical Astellas Pharma Inc

2011-08-29 Application granted granted Critical

2011-08-29 Publication of DK1718322T3 publication Critical patent/DK1718322T3/da

Links

239000000203 mixture Substances 0.000 title 1
230000002195 synergetic effect Effects 0.000 title 1
239000002246 antineoplastic agent Substances 0.000 abstract 6
230000000259 anti-tumor effect Effects 0.000 abstract 2
229940123237 Taxane Drugs 0.000 abstract 1
230000000340 anti-metabolite Effects 0.000 abstract 1
229940100197 antimetabolite Drugs 0.000 abstract 1
239000002256 antimetabolite Substances 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
229940121372 histone deacetylase inhibitor Drugs 0.000 abstract 1
239000003276 histone deacetylase inhibitor Substances 0.000 abstract 1
DKPFODGZWDEEBT-QFIAKTPHSA-N taxane Chemical class C([C@]1(C)CCC[C@@H](C)[C@H]1C1)C[C@H]2[C@H](C)CC[C@@H]1C2(C)C DKPFODGZWDEEBT-QFIAKTPHSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Oncology (AREA)
Hematology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Compositions Of Macromolecular Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DK05719967.1T 2004-02-25 2005-02-25 Synergistiske sammensætninger med FK-228 DK1718322T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP2004050520		2004-02-25
US56607704P	2004-04-29	2004-04-29
PCT/JP2005/003689 WO2005079827A2 (en)	2004-02-25	2005-02-25	Antitumor agent

Publications (1)

Publication Number	Publication Date
DK1718322T3 true DK1718322T3 (da)	2011-08-29

Family

ID=34889383

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK05719967.1T DK1718322T3 (da)	2004-02-25	2005-02-25	Synergistiske sammensætninger med FK-228

Country Status (11)

Country	Link
US (2)	US7951780B2 (da)
EP (1)	EP1718322B1 (da)
JP (1)	JP4930055B2 (da)
AT (1)	ATE516041T1 (da)
CA (1)	CA2557540A1 (da)
CY (1)	CY1111926T1 (da)
DK (1)	DK1718322T3 (da)
PL (1)	PL1718322T3 (da)
PT (1)	PT1718322E (da)
SI (1)	SI1718322T1 (da)
WO (1)	WO2005079827A2 (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HU229521B1 (hu) *	2001-08-21	2014-01-28	Astellas Pharma Inc	A hiszton-dezacetiláz inhibitor gyógyászati alkalmazása, és eljárás tumorellenes hatásának kiértékelésére
MXPA04009761A (es) *	2002-04-05	2005-05-27	Fujisawa Pharmaceutical Co	Dipsipeptido para terapia de cancer renal.
US20080233562A1 (en) *	2003-02-19	2008-09-25	Astellas Pharma Inc.	Method of Estimating Antitumor Effect of Histone Deacetylase Inhibitor
PL1670514T3 (pl) *	2003-09-25	2010-11-30	Astellas Pharma Inc	Środek przeciwnowotworowy zawierający inhibitor deacetylazy histonowej i inhibitor topoizomerazy II
US7951780B2 (en)	2004-02-25	2011-05-31	Astellas Pharma Inc.	Antitumor agent
CA2636596A1 (en) *	2005-11-04	2007-05-18	James Pluda	Method of treating cancers with saha and pemetrexed
EP1965824A4 (en) *	2005-11-18	2011-10-19	Gloucester Pharmaceuticals Inc	METABOLITENE DERIVATIVES OF HDAC INHIBITOR FK228
WO2007145704A2 (en) *	2006-04-24	2007-12-21	Gloucester Pharmaceuticals	Gemcitabine combination therapy
US8957027B2 (en)	2006-06-08	2015-02-17	Celgene Corporation	Deacetylase inhibitor therapy
DK2073837T3 (da) *	2006-10-06	2014-09-29	Bavarian Nordic Inc	Rekombinant modificeret vaccinia-ankara-virus, der koder for et her-2-antigen, i kombination med en taxan til anvendelse til behandling af cancer
EP2450049A1 (en) *	2006-12-29	2012-05-09	Gloucester Pharmaceuticals, Inc.	Romidepsin-based treatments for cancer
WO2008083288A2 (en) *	2006-12-29	2008-07-10	Gloucester Pharmaceuticals	Purifiction of romidepsin
WO2010036404A2 (en) *	2008-05-09	2010-04-01	University Of Maryland, Baltimore	Novel retinamide retinoic acid metabolism blocking agents
EP2366398A1 (en) *	2010-03-17	2011-09-21	Deutsches Krebsforschungszentrum	Cancer therapy with a parvovirus combined with an HDAC inhibitor
WO2011156119A1 (en) *	2010-06-07	2011-12-15	Abraxis Bioscience, Llc	Combination therapy methods for treating proliferative diseases
SG10201505475XA (en)	2010-07-12	2015-09-29	Celgene Corp	Romidepsin solid forms and uses thereof
US8859502B2 (en)	2010-09-13	2014-10-14	Celgene Corporation	Therapy for MLL-rearranged leukemia
AU2013202506B2 (en)	2012-09-07	2015-06-18	Celgene Corporation	Resistance biomarkers for hdac inhibitors
AU2013202507B9 (en)	2012-11-14	2015-08-13	Celgene Corporation	Inhibition of drug resistant cancer cells
NZ630311A (en)	2013-12-27	2016-03-31	Celgene Corp	Romidepsin formulations and uses thereof
CN106860872B (zh) *	2017-01-18	2019-03-22	上海交通大学	用于逆转肿瘤对铂类抗癌药多药耐药性的两亲性药-药纳米颗粒药物及其制备方法与应用

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8817743D0 (en)	1988-07-26	1988-09-01	Fujisawa Pharmaceutical Co	Fr901228 substance & preparation thereof
JPH0315810A (ja) *	1989-06-13	1991-01-24	Minolta Camera Co Ltd	カメラ
AU734476B2 (en) *	1997-11-05	2001-06-14	Baylor College Of Medicine	Sequences for targeting metastatic cells
WO2001034131A2 (en) *	1999-11-10	2001-05-17	Warner-Lambert Company	Combination chemotherapy
EP1779859B1 (en) *	1999-12-08	2010-06-09	Cyclacel Pharmaceuticals, Inc.	Use of depsipeptide and congeners thereof as immunosuppressants in preventing or treating rejection following transplantation and for induction of apoptosis of activated CD4 or CD8 T-cells
ATE425177T1 (de)	2000-07-17	2009-03-15	Astellas Pharma Inc	Reduziertes fk228 und seine verwendung
US7396665B2 (en)	2000-09-01	2008-07-08	Astellas Pharma, Inc.	Method of producing FR901228
JP2004528278A (ja) *	2000-12-18	2004-09-16	ボードオブレジェンツ，ザユニバーシティーオブテキサスシステム	インサイチュヒドロゲルを用いた、局所領域の化学療法および放射線治療
US6905669B2 (en) *	2001-04-24	2005-06-14	Supergen, Inc.	Compositions and methods for reestablishing gene transcription through inhibition of DNA methylation and histone deacetylase
US6620816B2 (en) *	2001-04-26	2003-09-16	Bristol-Myers Squibb Company	Method for treating tumors by the administration of tegafur, uracil, folinic acid, and cyclophosphamide
HU229521B1 (hu)	2001-08-21	2014-01-28	Astellas Pharma Inc	A hiszton-dezacetiláz inhibitor gyógyászati alkalmazása, és eljárás tumorellenes hatásának kiértékelésére
SK1102004A3 (sk) *	2001-08-31	2005-05-05	Bristol-Myers Squibb Company	Liečivo na liečenie proliferačných ochorení a farmaceutická kompozícia na liečenie rakoviny
EP1293205A1 (en)	2001-09-18	2003-03-19	G2M Cancer Drugs AG	Valproic acid and derivatives thereof for the combination therapy of human cancers, for the treatment of tumour metastasis and minimal residual disease
MXPA04009761A (es)	2002-04-05	2005-05-27	Fujisawa Pharmaceutical Co	Dipsipeptido para terapia de cancer renal.
CN100566711C (zh)	2002-04-15	2009-12-09	斯隆-凯特林癌症研究院	治疗癌症的化合物及其用途
PA8578001A1 (es) *	2002-08-07	2004-05-07	Warner Lambert Co	Combinaciones terapeuticas de inhibidores de quinasa de erb b y terapias antineoplasicas
US20050222013A1 (en)	2003-01-16	2005-10-06	Georgetown University	Methods for the use of inhibitors of histone deacetylase as synergistic agents in cancer therapy
US20080233562A1 (en)	2003-02-19	2008-09-25	Astellas Pharma Inc.	Method of Estimating Antitumor Effect of Histone Deacetylase Inhibitor
DK2238982T3 (da)	2003-06-27	2013-01-28	Astellas Pharma Inc	Terapeutisk middel til blødt væv-sarcom
CA2472842C (en)	2003-07-22	2012-05-29	Honda Motor Co., Ltd.	Working machine
PL1670514T3 (pl)	2003-09-25	2010-11-30	Astellas Pharma Inc	Środek przeciwnowotworowy zawierający inhibitor deacetylazy histonowej i inhibitor topoizomerazy II
US20050187148A1 (en)	2004-02-25	2005-08-25	Yoshinori Naoe	Antitumor agent
US7951780B2 (en)	2004-02-25	2011-05-31	Astellas Pharma Inc.	Antitumor agent

2005
- 2005-02-24 US US11/064,292 patent/US7951780B2/en not_active Expired - Lifetime
- 2005-02-25 WO PCT/JP2005/003689 patent/WO2005079827A2/en not_active Ceased
- 2005-02-25 JP JP2006526473A patent/JP4930055B2/ja not_active Expired - Lifetime
- 2005-02-25 PL PL05719967T patent/PL1718322T3/pl unknown
- 2005-02-25 PT PT05719967T patent/PT1718322E/pt unknown
- 2005-02-25 SI SI200531350T patent/SI1718322T1/sl unknown
- 2005-02-25 AT AT05719967T patent/ATE516041T1/de active
- 2005-02-25 CA CA002557540A patent/CA2557540A1/en not_active Abandoned
- 2005-02-25 DK DK05719967.1T patent/DK1718322T3/da active
- 2005-02-25 EP EP05719967A patent/EP1718322B1/en not_active Expired - Lifetime
2011
- 2011-03-11 US US13/046,082 patent/US8822422B2/en active Active
- 2011-10-10 CY CY20111100965T patent/CY1111926T1/el unknown

Also Published As

Publication number	Publication date
US20050187149A1 (en)	2005-08-25
PT1718322E (pt)	2011-09-05
US7951780B2 (en)	2011-05-31
JP4930055B2 (ja)	2012-05-09
EP1718322B1 (en)	2011-07-13
WO2005079827A2 (en)	2005-09-01
US8822422B2 (en)	2014-09-02
WO2005079827A3 (en)	2005-12-08
EP1718322A2 (en)	2006-11-08
ATE516041T1 (de)	2011-07-15
PL1718322T3 (pl)	2011-12-30
CY1111926T1 (el)	2015-11-04
SI1718322T1 (sl)	2011-09-30
JP2007524650A (ja)	2007-08-30
US20110160295A1 (en)	2011-06-30
CA2557540A1 (en)	2005-09-01

Publication	Publication Date	Title
DK1718322T3 (da)	2011-08-29	Synergistiske sammensætninger med FK-228
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UA91848C2 (ru)	2010-09-10	Применение соединений диосметина в лечении и предотвращении тромботическим патологиям
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EP2357003A4 (en)	2013-01-23	COMPOSITION AGAINST CANCER WITH AN ANTI-TUMOR ACTIVE SUBSTANCE AND A SUBSTANCE CONDENSING THE L1CAM ACTIVITY AND EXPRESSION
DE602004014787D1 (de)	2008-08-14	Anti-tumorale formulierungen mit defibrotid allein oder in kombination mit anderen antitumoralen mitteln