NO20084253L - Tetrahydroisokinolinderivater for a forbedre hukommelsesfunksjon - Google Patents

Tetrahydroisokinolinderivater for a forbedre hukommelsesfunksjon

Info

Publication number
NO20084253L
NO20084253L NO20084253A NO20084253A NO20084253L NO 20084253 L NO20084253 L NO 20084253L NO 20084253 A NO20084253 A NO 20084253A NO 20084253 A NO20084253 A NO 20084253A NO 20084253 L NO20084253 L NO 20084253L
Authority
NO
Norway
Prior art keywords
memory function
tetrahydroisoquinoline derivatives
improve memory
tetrahydroisoquinoline
derivatives
Prior art date
Application number
NO20084253A
Other languages
English (en)
Inventor
Francois Jenck
Original Assignee
Actelion Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Actelion Pharmaceuticals Ltd filed Critical Actelion Pharmaceuticals Ltd
Publication of NO20084253L publication Critical patent/NO20084253L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Oppfinnelsen vedrører anvendelsen av tetrahydroisokinolinderivater for fremstilling av et medikament for å forbedre, opprettholde de og/eller gjenopprette alle stadier og/eller typer av kort-, mellomlang- og/eller langtidshukommelse.
NO20084253A 2006-03-15 2008-10-10 Tetrahydroisokinolinderivater for a forbedre hukommelsesfunksjon NO20084253L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IB2006050812 2006-03-15
PCT/IB2007/050868 WO2007105177A1 (en) 2006-03-15 2007-03-14 Tetrahydroisoquinoline derivatives to enhance memory function

Publications (1)

Publication Number Publication Date
NO20084253L true NO20084253L (no) 2008-10-10

Family

ID=38181192

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20084253A NO20084253L (no) 2006-03-15 2008-10-10 Tetrahydroisokinolinderivater for a forbedre hukommelsesfunksjon

Country Status (16)

Country Link
US (1) US20090082394A1 (no)
EP (1) EP1998774A1 (no)
JP (3) JP4582722B2 (no)
KR (1) KR101065239B1 (no)
CN (1) CN101400348A (no)
AU (1) AU2007226203A1 (no)
BR (1) BRPI0708913A2 (no)
CA (1) CA2644010A1 (no)
CR (1) CR10260A (no)
EA (1) EA015256B1 (no)
IL (1) IL194044A0 (no)
MA (1) MA30327B1 (no)
MX (1) MX2008011647A (no)
NO (1) NO20084253L (no)
UA (1) UA93903C2 (no)
WO (1) WO2007105177A1 (no)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2557163C (en) 2004-03-01 2011-08-16 Idorsia Pharmaceuticals Ltd Substituted 1,2,3,4-tetrahydroisoquinoline derivatives
AU2007226203A1 (en) * 2006-03-15 2007-09-20 Actelion Pharmaceuticals Ltd Tetrahydroisoquinoline derivatives to enhance memory function
DE602007012072D1 (de) * 2006-04-26 2011-03-03 Actelion Pharmaceuticals Ltd Orantagonisten
WO2008078291A1 (en) 2006-12-22 2008-07-03 Actelion Pharmaceuticals Ltd 5,6,7,8-tetrahydro-imidazo[1,5-a]pyrazine derivatives
MX2009010727A (es) * 2007-04-04 2009-10-26 Hoffmann La Roche Heterociclos como antagonistas de orexina.
PE20091010A1 (es) * 2007-10-10 2009-08-08 Actelion Pharmaceuticals Ltd Derivados de tetrahidroquinolina
EP2231155A4 (en) 2007-12-18 2011-09-14 Concert Pharmaceuticals Inc Tetrahydroisoquinoline DERIVATIVES
WO2009083903A1 (en) 2007-12-28 2009-07-09 Actelion Pharmaceuticals Ltd Trisubstituted 3,4-dihydro-1h-isoquinolin compound, process for its preparation, and its use
CN102076694A (zh) 2008-06-25 2011-05-25 埃科特莱茵药品有限公司 5，6，7，8-四氢-咪唑并[1，5-a]吡嗪化合物
WO2010095106A1 (en) 2009-02-20 2010-08-26 Actelion Pharmaceuticals Ltd Solid forms of ( 2r) -2- { ( is ) -6, 7 -dimethoxy- 1- [2- (4-triflu0r0methyl-phenyl) -ethyl] -3, 4-dihydr0-1h -isoquinolin-2-yl} -n-methyl-2-phenyl-acetamide hydrochloride
EP2608787B1 (en) 2010-08-24 2019-11-20 Idorsia Pharmaceuticals Ltd Proline sulfonamide derivatives as orexin receptor antagonists
AU2011304285B2 (en) 2010-09-22 2015-01-29 Eisai R&D Management Co., Ltd. Cyclopropane compound
CA2815179A1 (en) 2010-11-10 2012-05-18 Actelion Pharmaceuticals Ltd Lactam derivatives useful as orexin receptor antagonists
WO2012085857A1 (en) 2010-12-22 2012-06-28 Actelion Pharmaceuticals Ltd 3,8-diaza-bicyclo[4.2.0]oct-3-yl amides
CA2823877C (en) 2011-02-18 2020-01-07 Idorsia Pharmaceuticals Ltd Novel pyrazole and imidazole derivatives useful as orexin antagonists
WO2012114252A1 (en) 2011-02-21 2012-08-30 Actelion Pharmaceuticals Ltd Novel indole and pyrrolopyridine amides
WO2013050938A1 (en) 2011-10-04 2013-04-11 Actelion Pharmaceuticals Ltd 3,7-diazabicyclo[3.3.1]nonane and 9-oxa-3,7-diazabicyclo[3.3.1]nonane derivatives
ES2572703T3 (es) 2011-11-08 2016-06-01 Actelion Pharmaceuticals Ltd. Derivados de 2-(1,2,3-triazol-2-il)benzamida y 3-(1,2,3-triazol-2-il)picolinamida como antagonistas del receptor de orexina
ES2617863T3 (es) 2012-06-04 2017-06-20 Actelion Pharmaceuticals Ltd. Derivados de bencimidazol-prolina
EA201500399A1 (ru) 2012-10-10 2015-09-30 Актелион Фармасьютиклз Лтд. Антагонисты рецептора орексина, которые представляют собой производные [орто-би-(гетеро)арил]-[2-(мета-би-(гетеро)арил)пирролидин-1-ил]метанона
CA2902135A1 (en) 2013-03-12 2014-09-18 Actelion Pharmaceuticals Ltd Azetidine amide derivatives as orexin receptor antagonists
MY179862A (en) 2013-12-03 2020-11-18 Idorsia Pharmaceuticals Ltd Crystalline form of (s)-(2-(6-chloro-7-methyl-1h-benzo[d]imidazol-2-yl)-2-methylpyrrolidin-1 -yl)(5-methoxy-2-(2h-1,2,3-triazol-2-yl)phenyl)methanone and its use as orexin receptor antagonists
UA119151C2 (uk) 2013-12-03 2019-05-10 Ідорсія Фармасьютікалз Лтд КРИСТАЛІЧНА СОЛЬОВА ФОРМА (S)-(2-(6-ХЛОР-7-МЕТИЛ-1H-БЕНЗО[d]ІМІДАЗОЛ-2-ІЛ)-2-МЕТИЛПІРОЛІДИН-1-ІЛ)(5-МЕТОКСИ-2-(2H-1,2,3-ТРИАЗОЛ-2-ІЛ)ФЕНІЛ)МЕТАНОНУ ЯК АНТАГОНІСТ ОРЕКСИНОВОГО РЕЦЕПТОРА
SI3077391T1 (sl) 2013-12-04 2018-11-30 Idorsia Pharmaceuticals Ltd Uporaba benzimidazol-prolinskih derivatov
ES2843952T3 (es) 2014-10-23 2021-07-21 Eisai R&D Man Co Ltd Composiciones para tratar el insomnio
WO2020007964A1 (en) 2018-07-05 2020-01-09 Idorsia Pharmaceuticals Ltd 2-(2-azabicyclo[3.1.0]hexan-1-yl)-1h-benzimidazole derivatives
WO2020007977A1 (en) 2018-07-06 2020-01-09 Idorsia Pharmaceuticals Ltd 7-trifluoromethyl-[1,4]diazepan derivatives
WO2020099511A1 (en) 2018-11-14 2020-05-22 Idorsia Pharmaceuticals Ltd Benzimidazole-2-methyl-morpholine derivatives
AR129309A1 (es) 2022-05-13 2024-08-07 Idorsia Pharmaceuticals Ltd Derivados de hidrazina-n-carboxamida cíclica sustituida con tiazoloaril-metilo

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2703050B1 (fr) * 1993-03-24 1995-04-28 Adir Nouveaux dérivés bicycliques azotés, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
GB9319732D0 (en) * 1993-09-24 1993-11-10 Ucb Sa Use of (s)-alpha-ethyl-2-oxo-l-pyrrolidineacetamide for the treatment of anxiety
JP3942207B2 (ja) * 1995-02-17 2007-07-11 武田薬品工業株式会社 うつ性症状改善剤
BRPI0109200B8 (pt) * 2000-03-14 2021-05-25 Actelion Pharmaceuticals Ltd compostos e composições farmacêuticas
EP1288202A4 (en) * 2000-05-11 2003-07-02 Banyu Pharma Co Ltd N-acyltetrahydroisoquinoline derivatives
WO2002051232A2 (en) * 2000-12-27 2002-07-04 Actelion Pharmaceuticals Ltd. Novel benzazepines and related heterocyclic derivatives
DK1501804T3 (da) * 2002-04-26 2009-10-12 Hoffmann La Roche Isoquinolinderivat MAO-B-inhibitorer
ES2327737T3 (es) * 2003-03-26 2009-11-03 Actelion Pharmaceuticals Ltd. Derivados de tetrahidroisoquinolil acetamida para uso como antagonistas de receptores de orexina.
CA2557163C (en) * 2004-03-01 2011-08-16 Idorsia Pharmaceuticals Ltd Substituted 1,2,3,4-tetrahydroisoquinoline derivatives
FR2874011B1 (fr) * 2004-08-03 2007-06-15 Sanofi Synthelabo Derives de sulfonamides, leur preparation et leur application en therapeutique
AU2007226203A1 (en) * 2006-03-15 2007-09-20 Actelion Pharmaceuticals Ltd Tetrahydroisoquinoline derivatives to enhance memory function

Also Published As

Publication number Publication date
CA2644010A1 (en) 2007-09-20
WO2007105177A1 (en) 2007-09-20
KR101065239B1 (ko) 2011-09-16
EP1998774A1 (en) 2008-12-10
BRPI0708913A2 (pt) 2011-06-14
EA015256B1 (ru) 2011-06-30
CN101400348A (zh) 2009-04-01
MA30327B1 (fr) 2009-04-01
JP2010248237A (ja) 2010-11-04
MX2008011647A (es) 2008-09-22
IL194044A0 (en) 2009-09-22
KR20080103597A (ko) 2008-11-27
JP2010270127A (ja) 2010-12-02
UA93903C2 (ru) 2011-03-25
JP4582722B2 (ja) 2010-11-17
CR10260A (no) 2008-10-03
US20090082394A1 (en) 2009-03-26
EA200870357A1 (ru) 2009-02-27
AU2007226203A1 (en) 2007-09-20
JP2009530265A (ja) 2009-08-27

Similar Documents

Publication Publication Date Title
NO20084253L (no) Tetrahydroisokinolinderivater for a forbedre hukommelsesfunksjon
NO20082793L (no) Nye tiofenderivater
EA200801758A1 (ru) Лекарственные формы, устойчивые к самовольному изменению
TNSN08178A1 (en) Triazolopyridine derivatives as inhibitors of lipases and phospholipases
ATE447568T1 (de) Neue pyrinderivate
NO20052887D0 (no) Pyridazinonderivater som GSK-3Beta inhibitorer.
NO20090596L (no) Antivirale fosfinatforbindelser
WO2008070268A3 (en) Pharmaceutical compositions
WO2007106436A3 (en) Photoactive compounds and compositions and uses thereof
NO20082298L (no) Kaliumkanalinhibitorer
WO2009071689A3 (de) 5-halogen-substituierte oxindol-derivate und ihre verwendung zur behandlung von vasopressin-abhängigen erkrankungen
BRPI0717369A2 (pt) Composto, medicamento, composição farmacêutica que o contém e uso do composto.
UA91848C2 (ru) Применение соединений диосметина в лечении и предотвращении тромботическим патологиям
AR054507A1 (es) Sistema transdermico de vareniclina
NO20075140L (no) Fremgangsmater og preparater for modulering av vaskulaer integritet
CL2010001421A1 (es) Uso de dronedarona en la preparacion de medicamentos utiles para la prevencion de fibrilacion o aleteo auricular persistentes.
NO20091386L (no) Fenyloksyanilinderivater
WO2007130902A3 (en) Therapeutic cyclopentane derivatives
CY1110787T1 (el) Νεα μορφινικα παραγωγα
MY139425A (en) Pharmaceutical composition comprising 2,4-dichlorobenzyl alcohol and amylmetacresol
WO2007089743A3 (en) Potassium channel inhibitors
NO20085267L (no) Derivater av 2-alkoksy -3,4,5-trihydroksy-alkyl amider, fremstilling og anvendelse derav, samt sammensetninger inneholdende samme
ATE526972T1 (de) Kaliumkanalhemmer
WO2007014671A3 (de) KOMBINATIONEN MIT IKK-ß INHIBITOREN
CN300800506S (zh) 药品包装盒(抗宫炎片40片otc)

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application