DK171886D0 - Fremgangsmaade til bestemmelse af digoxinindhold i en biologisk proeve - Google Patents

Fremgangsmaade til bestemmelse af digoxinindhold i en biologisk proeve

Info

Publication number: DK171886D0
Authority: DK; Denmark
Prior art keywords: digoxin; sample solution; determining; protein complex; biological test
Prior art date: 1985-04-22

Application number

DK171886A

Other languages

English (en)

Other versions

DK164466B (da

DK164466C (da

DK171886A (da

Inventor

Bruce C Farrenkopf

Richard A Kaufman

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-04-22

Filing date

1986-04-15

Publication date

1986-04-15

1986-04-15 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1986-04-15 Publication of DK171886D0 publication Critical patent/DK171886D0/da

1986-10-23 Publication of DK171886A publication Critical patent/DK171886A/da

1992-06-29 Publication of DK164466B publication Critical patent/DK164466B/da

1992-11-16 Application granted granted Critical

1992-11-16 Publication of DK164466C publication Critical patent/DK164466C/da

Links

LTMHDMANZUZIPE-AMTYYWEZSA-N Digoxin Natural products O([C@H]1[C@H](C)O[C@H](O[C@@H]2C[C@@H]3[C@@](C)([C@@H]4[C@H]([C@]5(O)[C@](C)([C@H](O)C4)[C@H](C4=CC(=O)OC4)CC5)CC3)CC2)C[C@@H]1O)[C@H]1O[C@H](C)[C@@H](O[C@H]2O[C@@H](C)[C@H](O)[C@@H](O)C2)[C@@H](O)C1 LTMHDMANZUZIPE-AMTYYWEZSA-N 0.000 title abstract 5
LTMHDMANZUZIPE-PUGKRICDSA-N digoxin Chemical compound C1[C@H](O)[C@H](O)[C@@H](C)O[C@H]1O[C@@H]1[C@@H](C)O[C@@H](O[C@@H]2[C@H](O[C@@H](O[C@@H]3C[C@@H]4[C@]([C@@H]5[C@H]([C@]6(CC[C@@H]([C@@]6(C)[C@H](O)C5)C=5COC(=O)C=5)O)CC4)(C)CC3)C[C@@H]2O)C)C[C@@H]1O LTMHDMANZUZIPE-PUGKRICDSA-N 0.000 title abstract 5
229960005156 digoxin Drugs 0.000 title abstract 5
LTMHDMANZUZIPE-UHFFFAOYSA-N digoxine Natural products C1C(O)C(O)C(C)OC1OC1C(C)OC(OC2C(OC(OC3CC4C(C5C(C6(CCC(C6(C)C(O)C5)C=5COC(=O)C=5)O)CC4)(C)CC3)CC2O)C)CC1O LTMHDMANZUZIPE-UHFFFAOYSA-N 0.000 title abstract 5
238000000034 method Methods 0.000 title abstract 4
239000012488 sample solution Substances 0.000 abstract 4
102000004506 Blood Proteins Human genes 0.000 abstract 2
108010017384 Blood Proteins Proteins 0.000 abstract 2
LOUPRKONTZGTKE-LHHVKLHASA-N quinidine Chemical compound C([C@H]([C@H](C1)C=C)C2)C[N@@]1[C@H]2[C@@H](O)C1=CC=NC2=CC=C(OC)C=C21 LOUPRKONTZGTKE-LHHVKLHASA-N 0.000 abstract 2
GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 abstract 2
229940087168 alpha tocopherol Drugs 0.000 abstract 1
239000013060 biological fluid Substances 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
LOUPRKONTZGTKE-UHFFFAOYSA-N cinchonine Natural products C1C(C(C2)C=C)CCN2C1C(O)C1=CC=NC2=CC=C(OC)C=C21 LOUPRKONTZGTKE-UHFFFAOYSA-N 0.000 abstract 1
238000010494 dissociation reaction Methods 0.000 abstract 1
230000005593 dissociations Effects 0.000 abstract 1
238000002875 fluorescence polarization Methods 0.000 abstract 1
229960001404 quinidine Drugs 0.000 abstract 1
239000000523 sample Substances 0.000 abstract 1
229920006395 saturated elastomer Polymers 0.000 abstract 1
150000004671 saturated fatty acids Chemical class 0.000 abstract 1
229960000984 tocofersolan Drugs 0.000 abstract 1
235000021122 unsaturated fatty acids Nutrition 0.000 abstract 1
150000004670 unsaturated fatty acids Chemical class 0.000 abstract 1
239000002076 α-tocopherol Substances 0.000 abstract 1
235000004835 α-tocopherol Nutrition 0.000 abstract 1

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
- G01N33/9453—Cardioregulators, e.g. antihypotensives, antiarrhythmics
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/807—Apparatus included in process claim, e.g. physical support structures
- Y10S436/808—Automated or kit
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/815—Test for named compound or class of compounds
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/825—Pretreatment for removal of interfering factors from sample
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Urology & Nephrology (AREA)
Hematology (AREA)
Chemical & Material Sciences (AREA)
Immunology (AREA)
Biomedical Technology (AREA)
Medicinal Chemistry (AREA)
Physics & Mathematics (AREA)
Biotechnology (AREA)
Heart & Thoracic Surgery (AREA)
Microbiology (AREA)
Cardiology (AREA)
Pharmacology & Pharmacy (AREA)
Food Science & Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Cell Biology (AREA)
Analytical Chemistry (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Investigating Or Analysing Biological Materials (AREA)
Steroid Compounds (AREA)
Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

DK171886A 1985-04-22 1986-04-15 Fremgangsmaade og reagenssaet til bestemmelse af digoxinindhold i en biologisk proeve DK164466C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US72625585		1985-04-22
US06/726,255 US4698315A (en)	1985-04-22	1985-04-22	Method and kit for determining total digoxin levels involving agent to dissociate digoxin-protein complex

Publications (4)

Publication Number	Publication Date
DK171886D0 true DK171886D0 (da)	1986-04-15
DK171886A DK171886A (da)	1986-10-23
DK164466B DK164466B (da)	1992-06-29
DK164466C DK164466C (da)	1992-11-16

Family

ID=24917828

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK171886A DK164466C (da)	1985-04-22	1986-04-15	Fremgangsmaade og reagenssaet til bestemmelse af digoxinindhold i en biologisk proeve

Country Status (12)

Country	Link
US (1)	US4698315A (da)
EP (1)	EP0199254B1 (da)
JP (1)	JPH0718872B2 (da)
AT (1)	ATE55651T1 (da)
AU (1)	AU599025B2 (da)
CA (1)	CA1268705A (da)
DE (1)	DE3673444D1 (da)
DK (1)	DK164466C (da)
ES (1)	ES8706261A1 (da)
FI (1)	FI84106C (da)
NO (1)	NO166149C (da)
NZ (1)	NZ215813A (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4734378A (en) *	1985-06-26	1988-03-29	Abbott Laboratories	Precipitation of interfering proteins in fluorescence polarization immunoassay for digoxin
US5501949A (en)	1985-12-10	1996-03-26	Murex Diagnostics Corporation	Particle bound binding component immunoassay
US4798804A (en) *	1987-02-05	1989-01-17	Syntex (U.S.A.) Inc.	Serum pretreatment in digoxin immunoassay
RU2132553C1 (ru) *	1996-05-30	1999-06-27	Ивановская Елена Алексеевна	Количественное определение дигоксина в сыворотке крови методом инверсионной вольтамперометрии
CN114964939B (zh) *	2021-12-20	2024-09-13	上海云泽生物科技有限公司	一种药物-蛋白解离组合物、含其的环孢霉素检测试剂盒及应用
CN220694891U (zh)	2023-06-20	2024-04-02	中山市特凯斯婴童用品有限公司	一种具有高度调节装置的婴儿提篮

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2410033C2 (de) *	1974-03-02	1975-09-11	Merck Patent Gmbh, 6100 Darmstadt	Isolierung von in lipophilen Lösungsmitteln löslichen Inhaltstoffen wäßriger Lösungen
AU555213B2 (en) *	1981-02-17	1986-09-18	Abbott Laboratories	N-substituted-amido-fluoresein derivatives
NZ199629A (en) *	1981-02-17	1984-11-09	Abbott Lab	Fluorescent polarisation immunoassay and certain substituted carboxy fluoresceins
US4492762A (en) *	1981-12-11	1985-01-08	Abbott Laboratories	Fluorescent polarization immunoassays
DE3230527A1 (de) *	1982-08-17	1984-02-23	A. Nattermann & Cie GmbH, 5000 Köln	Screening methode
CA1195995A (en) *	1982-11-08	1985-10-29	Curtis L. Kirkemo	Substituted carboxyfluoresceins
US4489165A (en) *	1983-01-24	1984-12-18	Becton Dickinson And Company	Chromogenic tracers for use in an assay
US4670406A (en) *	1984-01-06	1987-06-02	Becton Dickinson And Company	Tracers for use in assays

1985
- 1985-04-22 US US06/726,255 patent/US4698315A/en not_active Expired - Fee Related
1986
- 1986-04-14 NZ NZ215813A patent/NZ215813A/xx unknown
- 1986-04-14 FI FI861568A patent/FI84106C/fi not_active IP Right Cessation
- 1986-04-15 EP EP86105158A patent/EP0199254B1/de not_active Expired - Lifetime
- 1986-04-15 DK DK171886A patent/DK164466C/da not_active IP Right Cessation
- 1986-04-15 AT AT86105158T patent/ATE55651T1/de not_active IP Right Cessation
- 1986-04-15 DE DE8686105158T patent/DE3673444D1/de not_active Expired - Lifetime
- 1986-04-17 CA CA000506966A patent/CA1268705A/en not_active Expired - Lifetime
- 1986-04-21 NO NO861564A patent/NO166149C/no unknown
- 1986-04-21 ES ES554179A patent/ES8706261A1/es not_active Expired
- 1986-04-21 JP JP61091962A patent/JPH0718872B2/ja not_active Expired - Lifetime
- 1986-04-22 AU AU56464/86A patent/AU599025B2/en not_active Ceased

Also Published As

Publication number	Publication date
AU599025B2 (en)	1990-07-12
NO166149B (no)	1991-02-25
AU5646486A (en)	1986-10-30
FI861568A7 (fi)	1986-10-23
DK164466B (da)	1992-06-29
US4698315A (en)	1987-10-06
ES554179A0 (es)	1987-06-01
FI84106C (fi)	1991-10-10
NO166149C (no)	1991-06-05
FI861568A0 (fi)	1986-04-14
JPS61245059A (ja)	1986-10-31
CA1268705A (en)	1990-05-08
EP0199254B1 (de)	1990-08-16
EP0199254A1 (de)	1986-10-29
JPH0718872B2 (ja)	1995-03-06
DK164466C (da)	1992-11-16
FI84106B (fi)	1991-06-28
ATE55651T1 (de)	1990-09-15
NO861564L (no)	1986-10-23
NZ215813A (en)	1989-10-27
ES8706261A1 (es)	1987-06-01
DK171886A (da)	1986-10-23
DE3673444D1 (de)	1990-09-20

Legal Events

Date	Code	Title
1995-12-27	PBP	Patent lapsed
1997-08-04	B1	Patent granted (law 1993)
2001-12-31	PBP	Patent lapsed

Publication	Publication Date	Title
SE8600454D0 (sv)	1986-02-03	Test kit for determining the presence of organic materials and method of utilizing same
NO930770L (no)	1993-09-06	Immunologisk fremgangsmaate for bestemmelse av et hemoglobinderivat
DE3851967D1 (de)	1994-12-08	Verfahren zur Bestimmung von Antikörpern.
LV10538A (lv)	1995-02-20	Imunologiski saistamas vielas noteiksanas panemiens biologiska skidruma un diagnostikas lidzeklis
DE69429192D1 (de)	2002-01-03	Ein verfahren zur bestimmung von kollagenfragmenten in körperflüssigkeiten, ein testkit und mittel zur durchführung des verfahrens, und seine verwendung zur feststellung von mit dem kollagenmetabolismus assoziierten störungen
ES2033266T3 (es)	1993-03-16	Procedimiento y estuche de ensayo para la determinacion de sustancias activas libres en liquidos biologicos.
DK314987D0 (da)	1987-06-19	Fremgangsmaade til specifik bestemmelse af serumfructosaminindhold samt hertil egnet reagensblanding
US5922186A (en)	1999-07-13	Staining, de-staining and quantification of proteins by coomassie-blue and related dyes
DK171886A (da)	1986-10-23	Fremgangsmaade til bestemmelse af digoxinindhold i en biologisk proeve
DK0385452T3 (da)	1994-06-20	Carboxylsyreamider, som danner lipofile komplekser med magnesiumioner, fremgangsmåde til fremstilling af de lipofile magnesiumkoplekser og ionselektive dele
DK149830C (da)	1987-02-16	Fremgangsmaade ved bestemmelse af koncentrationen af en ion i en praeve af blod eller blodvaeske
ATE5749T1 (de)	1984-01-15	Verfahren und diagnostisches mittel zur direkten bestimmung des lipidgehaltes der betalipoproteine des blutes.
ATE81800T1 (de)	1992-11-15	Mikrotitrationsplatte und verfahren zur quantitativen bestimmung des zustandes oder von zustandsaenderungen von inhomogenen proben.
DK173884D0 (da)	1984-03-30	Fremgangsmaade til kvantitativ bestemmelse af haemoglobinkoncentrationen i en biologisk proeve
SE8203564L (sv)	1983-12-10	Forfarande for forbehandling av prover som forutom mikroorganismer even innehaller annat biologiskt material
ATE154846T1 (de)	1997-07-15	Satz zur schnellen aufzählung von granulocyten und verfahren das diesen satz verwendet
Benson et al.	1986	Assessing the specificity of anti-canine-factor VIII-related antigen
DE3786351D1 (de)	1993-07-29	Festphasenimmunoassayverfahren.
GB2011070A (en)	1979-07-04	Assay of vitamin B12
JPS57125352A (en)	1982-08-04	Method and kit for preparing sample used for testing endotoxin with water-insoluble antihomo alpha2-macroglobulin antibody
DE3765223D1 (de)	1990-10-31	Verfahren zur bestimmung von parathormon.
Lockyer	1970	Syphilis screening using the multi-channel blood-grouping machine
Roy	1991	Haptoglobin typing from fatty tissues after extraction with non-ionic detergents
FR2343250A1 (fr)	1977-09-30	Procede pour la mise en evidence d'antigenes t, notamment de ceux des lymphocytes t dans un milieu biologique