DK1720823T3 - Ny fremgangsmåde til syntese af substituerede alpha-amino-indanderivater - Google Patents
Ny fremgangsmåde til syntese af substituerede alpha-amino-indanderivaterInfo
- Publication number
- DK1720823T3 DK1720823T3 DK05708645T DK05708645T DK1720823T3 DK 1720823 T3 DK1720823 T3 DK 1720823T3 DK 05708645 T DK05708645 T DK 05708645T DK 05708645 T DK05708645 T DK 05708645T DK 1720823 T3 DK1720823 T3 DK 1720823T3
- Authority
- DK
- Denmark
- Prior art keywords
- formula
- substituted alpha
- synthesis
- new method
- chem
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- 150000001408 amides Chemical class 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 238000009876 asymmetric hydrogenation reaction Methods 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/24—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
- C07C233/25—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Catalysts (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04290444A EP1574498A1 (fr) | 2004-02-19 | 2004-02-19 | Procédé de synthèse de derivés de alpha-aminoindane substitués |
| PCT/IB2005/000534 WO2005082838A1 (fr) | 2004-02-19 | 2005-02-21 | Nouveau procede de synthese de derives d'alpha-aminoindan substitues |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1720823T3 true DK1720823T3 (da) | 2009-11-09 |
Family
ID=34814414
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK05708645T DK1720823T3 (da) | 2004-02-19 | 2005-02-21 | Ny fremgangsmåde til syntese af substituerede alpha-amino-indanderivater |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7456320B2 (fr) |
| EP (2) | EP1574498A1 (fr) |
| JP (1) | JP4790636B2 (fr) |
| KR (1) | KR101239184B1 (fr) |
| CN (1) | CN1910134A (fr) |
| AT (1) | ATE440816T1 (fr) |
| DE (1) | DE602005016223D1 (fr) |
| DK (1) | DK1720823T3 (fr) |
| ES (1) | ES2331011T3 (fr) |
| IL (1) | IL177431A (fr) |
| WO (1) | WO2005082838A1 (fr) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1547997A1 (fr) * | 2003-12-22 | 2005-06-29 | Ppg - Sipsy | Procédé de préparation de dérivés d'enamides |
| WO2006029135A1 (fr) * | 2004-09-08 | 2006-03-16 | Teva Pharmaceutical Usa, Inc | Procede ameliore pour la synthese de derives d'indanylamine ou d'aminotetraline et nouveaux produits intermediaires |
| US20070238893A1 (en) * | 2005-11-04 | 2007-10-11 | Lee Boulton | Asymmetric hydrogenation of acyl enamides |
| JP5312743B2 (ja) * | 2006-02-01 | 2013-10-09 | 富士フイルム株式会社 | オキシム化合物及びそれを含む感光性組成物 |
| CN101421228B (zh) * | 2006-03-31 | 2014-05-21 | 塞普拉柯公司 | 手性酰胺和胺的制备 |
| JP2008249857A (ja) * | 2007-03-29 | 2008-10-16 | Fujifilm Corp | 感光性樹脂組成物、カラーフィルタ及びその製造方法、並びに液晶表示素子 |
| WO2008090640A1 (fr) * | 2007-01-23 | 2008-07-31 | Fujifilm Corporation | Composé d'oxime, composition photosensible, filtre coloré, procédé de fabrication du filtre coloré, et élément d'affichage à cristaux liquides |
| KR101692593B1 (ko) * | 2014-11-18 | 2017-01-03 | 포항공과대학교 산학협력단 | 유기 아자이드 및 아실 주개로부터 엔아마이드를 제조하는 방법 |
| CN105085285A (zh) * | 2015-08-26 | 2015-11-25 | 吴玲 | 一种制备r-6-甲氧基-1-氨基茚满的方法 |
| CN111777631A (zh) * | 2020-07-07 | 2020-10-16 | 上海体育学院 | 一种多取代茚化合物、茚醇类衍生物及其制备方法 |
| CN111978144A (zh) * | 2020-09-16 | 2020-11-24 | 河北凡克新材料有限公司 | 一种环己基多氟苯类液晶单体的制备方法 |
| CN113698319B (zh) * | 2021-04-27 | 2024-09-10 | 偶极医药科技(徐州)有限公司 | 一种奥扎莫德中间体的制备方法 |
| CN113801033B (zh) * | 2021-11-16 | 2022-02-08 | 苏州欣诺科生物科技有限公司 | 2-氨基茚满或其衍生物的合成方法 |
| CN118239990B (zh) * | 2024-05-28 | 2025-03-14 | 北京元延医药科技股份有限公司 | 不对称氢化催化合成药物的稀有贵金属和手性膦的配合物 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS54157551A (en) * | 1978-05-30 | 1979-12-12 | Hokuriku Pharmaceutical | Indanamine derivative |
| JPS635063A (ja) * | 1986-06-26 | 1988-01-11 | Taiyo Yakuhin Kogyo Kk | インダン類化合物 |
| JPH054950A (ja) * | 1991-07-02 | 1993-01-14 | Otsuka Pharmaceut Co Ltd | ２，３−ジヒドロ−１ｈ−インデン誘導体 |
| ES2241064T3 (es) * | 1996-12-18 | 2005-10-16 | Teva Pharmaceutical Industries, Ltd. | Derivados de aminoindano. |
| WO1999018065A1 (fr) * | 1997-10-03 | 1999-04-15 | Chirotech Technology Limited | Amines chirales |
| WO1999059721A1 (fr) * | 1998-05-18 | 1999-11-25 | The Penn State Research Foundation | Hydrogenation catalytique asymetrique, hydroformulation, et hydrovinylation via des catalyseurs a metaux de transition avec phosphines et phosphites |
| JP2001226333A (ja) * | 2000-02-09 | 2001-08-21 | Kemikurea:Kk | 光学活性アミノインダン誘導体の製造方法およびその中間体 |
| WO2006029135A1 (fr) * | 2004-09-08 | 2006-03-16 | Teva Pharmaceutical Usa, Inc | Procede ameliore pour la synthese de derives d'indanylamine ou d'aminotetraline et nouveaux produits intermediaires |
-
2004
- 2004-02-19 EP EP04290444A patent/EP1574498A1/fr not_active Withdrawn
-
2005
- 2005-02-21 EP EP05708645A patent/EP1720823B1/fr not_active Expired - Lifetime
- 2005-02-21 JP JP2006553705A patent/JP4790636B2/ja not_active Expired - Fee Related
- 2005-02-21 DK DK05708645T patent/DK1720823T3/da active
- 2005-02-21 WO PCT/IB2005/000534 patent/WO2005082838A1/fr not_active Ceased
- 2005-02-21 DE DE602005016223T patent/DE602005016223D1/de not_active Expired - Lifetime
- 2005-02-21 AT AT05708645T patent/ATE440816T1/de active
- 2005-02-21 US US10/589,529 patent/US7456320B2/en not_active Expired - Lifetime
- 2005-02-21 KR KR1020067016096A patent/KR101239184B1/ko not_active Expired - Fee Related
- 2005-02-21 ES ES05708645T patent/ES2331011T3/es not_active Expired - Lifetime
- 2005-02-21 CN CNA2005800026636A patent/CN1910134A/zh active Pending
-
2006
- 2006-08-10 IL IL177431A patent/IL177431A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| ES2331011T3 (es) | 2009-12-18 |
| IL177431A (en) | 2012-03-29 |
| IL177431A0 (en) | 2006-12-10 |
| US7456320B2 (en) | 2008-11-25 |
| CN1910134A (zh) | 2007-02-07 |
| JP4790636B2 (ja) | 2011-10-12 |
| JP2007523154A (ja) | 2007-08-16 |
| EP1720823A1 (fr) | 2006-11-15 |
| KR101239184B1 (ko) | 2013-03-05 |
| EP1574498A1 (fr) | 2005-09-14 |
| KR20060126767A (ko) | 2006-12-08 |
| WO2005082838A1 (fr) | 2005-09-09 |
| DE602005016223D1 (de) | 2009-10-08 |
| US20070191640A1 (en) | 2007-08-16 |
| ATE440816T1 (de) | 2009-09-15 |
| EP1720823B1 (fr) | 2009-08-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK1720823T3 (da) | Ny fremgangsmåde til syntese af substituerede alpha-amino-indanderivater | |
| DK1799635T3 (da) | Forbedret synteseskema for lacosamid | |
| EA200870262A1 (ru) | Способ получения оптических активных хиральных аминов | |
| DK1940348T3 (da) | Sammensætning omfattende et koblet enzymsystem | |
| EA201101015A1 (ru) | Способ получения бивалирудина | |
| EA200600621A1 (ru) | Производные тетрагидронафталина, способ их получения и их применение в качестве противовоспалительных средств | |
| UY32034A (es) | Nuevo procedimiento de resolución de enantiómeros de (3,4-dimetoxi-biciclo[4.2.0]octa-1,3,5-trien-7-il)nitrilo y aplicación en la sistesis de ivabradina | |
| DE602005008402D1 (de) | Stereoselektive synthese bestimmter trifluormethylsubstituierter alkohole | |
| ATE523480T1 (de) | Direkte einstufen-synthese von cf3-i | |
| CY1110688T1 (el) | Διεργασια για την παρασκευη καρβεδιλολης και εναντιομερων αυτης | |
| NO20081617L (no) | Metoder for fremstilling av Glutaminsyrederivater | |
| ATE399775T1 (de) | Triphenylethyleneverbindungen als selektive modulatoren des östrogenrezeptors | |
| DK2300606T3 (da) | Fremgangsmåde til fremstilling af et kaseinhydrolysat | |
| ATE411994T1 (de) | Herstellung eines substituierten chinoxalins von hoher reinheit | |
| EA200701738A1 (ru) | Способ получения транс-1-((1r,3s)-6-хлор-3-фенилиндан-1-ил)-3,3-диметилпиперазина | |
| DE602006010584D1 (de) | Stereoselektive synthese bestimmter trifluormethylsubstituierter alkohole | |
| EA200700766A1 (ru) | Способ получения производных [1,4,5]-оксадиазепина | |
| EA200602169A1 (ru) | Способ получения производных 2-оксо-1-пирролидина внутримолекулярным аллилированием | |
| DK1877370T3 (da) | Fremgangsmåde til fremstilling af hydrazon-derivater | |
| BR0308347A (pt) | Processo para fabricação de piperazinas 1,4-dissubstituìdas quirais | |
| TW200719889A (en) | Amino acid derivatives | |
| DK1765770T3 (da) | Fremgangsmåde til fremstilling af gabapentin | |
| EA200501125A1 (ru) | Способ получения метил-2-дифенилметилсульфинилацетата | |
| DE602006015465D1 (de) | Cycloalkylidinverbindungen als selektive modulatoren des östrogenrezeptors | |
| BRPI0500773A (pt) | método para secagem de neotame com um co-agente para proporcionar um produto sólido contendo neotame, e, produto sólido contendo neotame possuindo uniformidade melhorada e estabilidade melhorada |