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Application filed by Erba FarmitaliafiledCriticalErba Farmitalia
Priority to DK173382ApriorityCriticalpatent/DK147262C/da
Priority to DK400283Aprioritypatent/DK147974C/da
Publication of DK173382ApublicationCriticalpatent/DK173382A/da
Publication of DK147262BpublicationCriticalpatent/DK147262B/da
Application grantedgrantedCritical
Publication of DK147262CpublicationCriticalpatent/DK147262C/da
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Saccharide Compounds
(AREA)
Description
hvor R er H eller OH, fremstilles ved mild alkalisk hydrolyse af 4*-deoxy-4'-iod-N-trifluoracetyldaunorubicin
for at fremstille 4'-deoxy-4’-ioddaunorubicin med formlen I, hvori R er H, og eventuelt omsætning af forbindelsen med brom til dannelse af 14-bromderivatet (hvor R er erstattet med Br) og behandling af dette derivat med vandig opløsning af natriumformiat til fremstilling af forbindelsen med formlen I, hvor R er OH.
Forbindelserne er lægemidler med kraftig antitumoral virkning.
DK173382A1982-04-191982-04-19Analogifremgangsmaade til fremstilling af 4'-deoxy-4'-ioddaunorubicin
DK147262C
(da)
