DK1740197T3 - Prolyl-endopeptidease (PEP) og glutamin-endoprotease til behandlingen af cøliaki - Google Patents

Prolyl-endopeptidease (PEP) og glutamin-endoprotease til behandlingen af cøliaki

Info

Publication number
DK1740197T3
DK1740197T3 DK05714080.8T DK05714080T DK1740197T3 DK 1740197 T3 DK1740197 T3 DK 1740197T3 DK 05714080 T DK05714080 T DK 05714080T DK 1740197 T3 DK1740197 T3 DK 1740197T3
Authority
DK
Denmark
Prior art keywords
endopeptidease
prolyl
pep
treatment
celiac disease
Prior art date
Application number
DK05714080.8T
Other languages
English (en)
Inventor
Lu Shan
Michael Bethune
Chaitan Khosla
Jonathan Gass
Original Assignee
Alvine Pharmaceuticals Inc
Univ Leland Stanford Junior
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alvine Pharmaceuticals Inc, Univ Leland Stanford Junior filed Critical Alvine Pharmaceuticals Inc
Application granted granted Critical
Publication of DK1740197T3 publication Critical patent/DK1740197T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4813—Exopeptidases (3.4.11. to 3.4.19)
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/06—Enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Microbiology (AREA)
  • Pulmonology (AREA)
  • Transplantation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
DK05714080.8T 2004-04-26 2005-02-23 Prolyl-endopeptidease (PEP) og glutamin-endoprotease til behandlingen af cøliaki DK1740197T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US56566804P 2004-04-26 2004-04-26
US10/969,314 US7320788B2 (en) 2002-02-14 2004-10-19 Enzyme treatment of foodstuffs for Celiac Sprue
PCT/US2005/006129 WO2005107786A1 (en) 2004-04-26 2005-02-23 Therapeutic enzyme formulations and uses thereof

Publications (1)

Publication Number Publication Date
DK1740197T3 true DK1740197T3 (da) 2013-11-11

Family

ID=35320040

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05714080.8T DK1740197T3 (da) 2004-04-26 2005-02-23 Prolyl-endopeptidease (PEP) og glutamin-endoprotease til behandlingen af cøliaki

Country Status (11)

Country Link
US (1) US7320788B2 (da)
EP (1) EP1740197B1 (da)
JP (3) JP2007534752A (da)
AU (1) AU2005239985B2 (da)
CA (1) CA2563505C (da)
DK (1) DK1740197T3 (da)
ES (1) ES2437569T3 (da)
NO (1) NO340598B1 (da)
PL (1) PL1740197T3 (da)
PT (1) PT1740197E (da)
WO (1) WO2005107786A1 (da)

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US8143210B2 (en) * 2002-02-14 2012-03-27 The Board Of Trustees Of The Leland Stanford Junior University Enzyme treatment of foodstuffs for celiac sprue
US7605150B2 (en) * 2002-05-14 2009-10-20 The Board Of Trustees Of The Leland Stanford Junior University Drug therapy for Celiac Sprue
US7462688B2 (en) * 2002-05-14 2008-12-09 The Board Of Trustees Of The Leland Stanford Junior University Peptides for diagnostic and therapeutic methods for celiac sprue
US7265093B2 (en) * 2002-05-14 2007-09-04 The Board Of Trustees Of The Leland Stanford Junior University Drug therapy for Celiac Sprue
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US7579313B2 (en) * 2003-11-18 2009-08-25 The Board Of Trustees Of The Leland Stanford Junior University Transglutaminase inhibitors and methods of use thereof
US10105437B2 (en) 2004-04-28 2018-10-23 Btg International Limited Epitopes related to coeliac disease
EP2486935B1 (en) 2004-04-28 2021-04-07 BTG International Limited Epitopes related to Coeliac Disease
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WO2006097949A1 (en) * 2005-03-16 2006-09-21 Actial Farmacêutica, Lda. Mixture of at least 6 species of lactic acid bacteria and/or bifidobacteria in the manufacture of sourdough
EP1949093A2 (en) * 2005-10-11 2008-07-30 Alvine Pharmaceuticals, Inc. Compositions and methods for enhanced gastrointestinal stability of oligopeptides and polypeptides
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CA2680590C (en) * 2007-03-16 2017-10-17 Jonathan David Gass Combination enzyme therapy for digestion of dietary gluten
US8148105B2 (en) * 2007-03-16 2012-04-03 The Board Of Trustees Of The Leland Stanford Junior University Scaleable manufacturing process for cysteine endoprotease B, isoform 2
WO2009075816A1 (en) * 2007-12-10 2009-06-18 The Board Of Trustees Of The Leland Stanford Junior University Combination enzyme therapy for gastric digestion of dietary gluten in celiac sprue patients
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US8685392B2 (en) 2009-10-07 2014-04-01 Trustees Of Boston University Rothia species glutamine endopeptidases and use thereof
JP2013518589A (ja) * 2010-02-02 2013-05-23 アマノ エンザイム ユーエスエー，リミテッド グルテン不耐性に対するプロテアーゼの使用
US20130121976A1 (en) * 2010-03-12 2013-05-16 Agusti Montserrat Carreras Lactic Acid Bacteria for Coeliac Disease
WO2012006384A2 (en) 2010-07-07 2012-01-12 Trustees Of Boston University Rothia species gluten-degrading enzymes and uses thereof
JP5937106B2 (ja) * 2011-01-20 2016-06-22 サイレックス ラボラトリーズ，エルエルシー グルテン感受性の検出およびグルテン感受性とセリアック病を鑑別するための方法ならびに装置
WO2012135646A2 (en) * 2011-03-30 2012-10-04 Alvine Pharmaceuticals, Inc. Proteases for degrading gluten
US20140248251A1 (en) 2011-07-25 2014-09-04 Daniel C. Adelman Methods and Pharmaceutical Compositions for Treating Celiac Disease and Gluten Intolerance
JP6342802B2 (ja) * 2011-08-10 2018-06-13 ザ ユニバーシティ オブ ワシントン スルー イッツ センター フォー コマーシャライゼーションＴｈｅ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｗａｓｈｉｎｇｔｏｎ Ｔｈｒｏｕｇｈ Ｉｔｓ Ｃｅｎｔｅｒ Ｆｏｒ Ｃｏｍｍｅｒｃｉａｌｉｚａｔｉｏｎ セリアックスプルー病を治療するための組成物および方法
JPWO2013047082A1 (ja) * 2011-09-29 2015-03-26 天野エンザイム株式会社 外因性オピオイドペプチド分解酵素剤
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WO2016054038A1 (en) 2014-09-29 2016-04-07 Immusant, Inc. Use of hla genetic status to assess or select treatment of celiac disease
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US10857214B2 (en) 2015-12-16 2020-12-08 Codexis, Inc. Compositions and methods for treating gluten intolerance and disorders arising therefrom
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WO2020087017A1 (en) * 2018-10-26 2020-04-30 The Regents Of The University Of California Use of proteolytic enzymes to enhance protein bioavailability
KR102184812B1 (ko) * 2018-12-13 2020-11-30 대한민국 새찰쌀보리 추출물을 포함하는 골다공증 예방 또는 치료용 조성물
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Also Published As

Publication number Publication date
JP2007534752A (ja) 2007-11-29
JP2015063554A (ja) 2015-04-09
EP1740197B1 (en) 2013-10-16
NO20065195L (no) 2007-01-18
PT1740197E (pt) 2013-12-02
CA2563505A1 (en) 2005-11-17
US7320788B2 (en) 2008-01-22
EP1740197A1 (en) 2007-01-10
AU2005239985A1 (en) 2005-11-17
PL1740197T3 (pl) 2014-03-31
ES2437569T3 (es) 2014-01-13
US20050249719A1 (en) 2005-11-10
AU2005239985B2 (en) 2010-08-12
EP1740197A4 (en) 2009-09-16
NO340598B1 (no) 2017-05-15
CA2563505C (en) 2020-09-08
JP2012092125A (ja) 2012-05-17
WO2005107786A1 (en) 2005-11-17

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