DK1740197T3 - Prolyl-endopeptidease (PEP) og glutamin-endoprotease til behandlingen af cøliaki - Google Patents

Prolyl-endopeptidease (PEP) og glutamin-endoprotease til behandlingen af cøliaki

Info

Publication number
DK1740197T3
DK1740197T3 DK05714080.8T DK05714080T DK1740197T3 DK 1740197 T3 DK1740197 T3 DK 1740197T3 DK 05714080 T DK05714080 T DK 05714080T DK 1740197 T3 DK1740197 T3 DK 1740197T3
Authority
DK
Denmark
Prior art keywords
endopeptidease
prolyl
pep
treatment
celiac disease
Prior art date
Application number
DK05714080.8T
Other languages
English (en)
Inventor
Lu Shan
Michael Bethune
Chaitan Khosla
Jonathan Gass
Original Assignee
Alvine Pharmaceuticals Inc
Univ Leland Stanford Junior
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alvine Pharmaceuticals Inc, Univ Leland Stanford Junior filed Critical Alvine Pharmaceuticals Inc
Application granted granted Critical
Publication of DK1740197T3 publication Critical patent/DK1740197T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4813Exopeptidases (3.4.11. to 3.4.19)
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L29/00Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/06Enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482Serine endopeptidases (3.4.21)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Microbiology (AREA)
  • Transplantation (AREA)
  • Pulmonology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK05714080.8T 2004-04-26 2005-02-23 Prolyl-endopeptidease (PEP) og glutamin-endoprotease til behandlingen af cøliaki DK1740197T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US56566804P 2004-04-26 2004-04-26
US10/969,314 US7320788B2 (en) 2002-02-14 2004-10-19 Enzyme treatment of foodstuffs for Celiac Sprue
PCT/US2005/006129 WO2005107786A1 (en) 2004-04-26 2005-02-23 Therapeutic enzyme formulations and uses thereof

Publications (1)

Publication Number Publication Date
DK1740197T3 true DK1740197T3 (da) 2013-11-11

Family

ID=35320040

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05714080.8T DK1740197T3 (da) 2004-04-26 2005-02-23 Prolyl-endopeptidease (PEP) og glutamin-endoprotease til behandlingen af cøliaki

Country Status (11)

Country Link
US (1) US7320788B2 (da)
EP (1) EP1740197B1 (da)
JP (3) JP2007534752A (da)
AU (1) AU2005239985B2 (da)
CA (1) CA2563505C (da)
DK (1) DK1740197T3 (da)
ES (1) ES2437569T3 (da)
NO (1) NO340598B1 (da)
PL (1) PL1740197T3 (da)
PT (1) PT1740197E (da)
WO (1) WO2005107786A1 (da)

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US7462688B2 (en) * 2002-05-14 2008-12-09 The Board Of Trustees Of The Leland Stanford Junior University Peptides for diagnostic and therapeutic methods for celiac sprue
US7265093B2 (en) * 2002-05-14 2007-09-04 The Board Of Trustees Of The Leland Stanford Junior University Drug therapy for Celiac Sprue
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WO2008115428A2 (en) * 2007-03-16 2008-09-25 The Board Of Trustees Of The Leland Stanford Junior University A scaleable manufacturing process for cysteine endoprotease b, isoform 2
WO2008115411A1 (en) * 2007-03-16 2008-09-25 The Board Of Trustees Of The Leland Stanford Junior University Combination enzyme therapy for digestion of dietary gluten
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US8685392B2 (en) 2009-10-07 2014-04-01 Trustees Of Boston University Rothia species glutamine endopeptidases and use thereof
EP2531521B1 (en) * 2010-02-02 2017-09-06 Amano Enzyme USA., Ltd. Use of proteases for gluten intolerance
CN103097513B (zh) * 2010-03-12 2018-01-30 热尔韦·达诺尼公司 用于乳糜泻的乳酸菌
US9598684B2 (en) 2010-07-07 2017-03-21 Trustees Of Boston University Rothia species gluten-degrading enzymes and uses thereof
CN107831318B (zh) * 2011-01-20 2021-06-18 西瑞斯实验室有限公司 检测谷蛋白敏感性和其区分于乳糜泻的方法和装置
WO2012135646A2 (en) * 2011-03-30 2012-10-04 Alvine Pharmaceuticals, Inc. Proteases for degrading gluten
WO2013016427A1 (en) 2011-07-25 2013-01-31 Alvine Pharmaceuticals, Inc. Methods and pharmaceutical compositions for treating celiac disease and gluten intolerance
CA2882502A1 (en) 2011-08-10 2013-02-14 University Of Washington Through Its Center For Commercialization Compositions and methods for treating celiac sprue disease
US20140219982A1 (en) * 2011-09-29 2014-08-07 Amano Enzyme Inc. Exogenous opioid peptide-degrading enzyme
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WO2014011662A2 (en) * 2012-07-09 2014-01-16 Alvine Pharmaceuticals, Inc. Acid stable prolyl endopeptidases for degrading gluten
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US10857214B2 (en) 2015-12-16 2020-12-08 Codexis, Inc. Compositions and methods for treating gluten intolerance and disorders arising therefrom
US20190307860A1 (en) 2016-11-23 2019-10-10 Immunogenics Llc Latiglutenase (alv003) for use in the treatment of symptomatic celiac disease, gluten intolerance or gluten sensitivity
WO2020087017A1 (en) * 2018-10-26 2020-04-30 The Regents Of The University Of California Use of proteolytic enzymes to enhance protein bioavailability
KR102184812B1 (ko) * 2018-12-13 2020-11-30 대한민국 새찰쌀보리 추출물을 포함하는 골다공증 예방 또는 치료용 조성물
JP7390398B2 (ja) * 2019-04-02 2023-12-01 サミ-サビンサ グループ リミテッド グルテン不耐性の治療管理のための方法および組成物
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IT201900012942A1 (it) 2019-07-25 2021-01-25 Nemysis Ltd Metodo per la produzione di una composizione enzimatica comprendente una endopeptidasi ricombinante
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Also Published As

Publication number Publication date
AU2005239985A1 (en) 2005-11-17
EP1740197A1 (en) 2007-01-10
NO340598B1 (no) 2017-05-15
EP1740197A4 (en) 2009-09-16
CA2563505A1 (en) 2005-11-17
JP2015063554A (ja) 2015-04-09
ES2437569T3 (es) 2014-01-13
EP1740197B1 (en) 2013-10-16
US20050249719A1 (en) 2005-11-10
WO2005107786A1 (en) 2005-11-17
JP2012092125A (ja) 2012-05-17
US7320788B2 (en) 2008-01-22
JP2007534752A (ja) 2007-11-29
AU2005239985B2 (en) 2010-08-12
PT1740197E (pt) 2013-12-02
PL1740197T3 (pl) 2014-03-31
CA2563505C (en) 2020-09-08
NO20065195L (no) 2007-01-18

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