PL1740197T3 - Endopeptydaza prolilowa (PEP) i endoproteaza glutaminowa w leczeniu celiakii - Google Patents

Endopeptydaza prolilowa (PEP) i endoproteaza glutaminowa w leczeniu celiakii

Info

Publication number
PL1740197T3
PL1740197T3 PL05714080T PL05714080T PL1740197T3 PL 1740197 T3 PL1740197 T3 PL 1740197T3 PL 05714080 T PL05714080 T PL 05714080T PL 05714080 T PL05714080 T PL 05714080T PL 1740197 T3 PL1740197 T3 PL 1740197T3
Authority
PL
Poland
Prior art keywords
endopeptidease
prolyl
pep
treatment
celiac sprue
Prior art date
Application number
PL05714080T
Other languages
English (en)
Inventor
Lu Shan
Michael Bethune
Chaitan Khosla
Jonathan Gass
Original Assignee
Alvine Pharmaceuticals Inc
Univ Leland Stanford Junior
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alvine Pharmaceuticals Inc, Univ Leland Stanford Junior filed Critical Alvine Pharmaceuticals Inc
Publication of PL1740197T3 publication Critical patent/PL1740197T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4813—Exopeptidases (3.4.11. to 3.4.19)
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/06—Enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Microbiology (AREA)
  • Transplantation (AREA)
  • Pulmonology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PL05714080T 2004-04-26 2005-02-23 Endopeptydaza prolilowa (PEP) i endoproteaza glutaminowa w leczeniu celiakii PL1740197T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US56566804P 2004-04-26 2004-04-26
US10/969,314 US7320788B2 (en) 2002-02-14 2004-10-19 Enzyme treatment of foodstuffs for Celiac Sprue
PCT/US2005/006129 WO2005107786A1 (en) 2004-04-26 2005-02-23 Therapeutic enzyme formulations and uses thereof
EP05714080.8A EP1740197B1 (en) 2004-04-26 2005-02-23 Prolyl endopeptidease (PEP) and glutamine endoprotease for the treatment of Celiac Sprue

Publications (1)

Publication Number Publication Date
PL1740197T3 true PL1740197T3 (pl) 2014-03-31

Family

ID=35320040

Family Applications (1)

Application Number Title Priority Date Filing Date
PL05714080T PL1740197T3 (pl) 2004-04-26 2005-02-23 Endopeptydaza prolilowa (PEP) i endoproteaza glutaminowa w leczeniu celiakii

Country Status (11)

Country Link
US (1) US7320788B2 (pl)
EP (1) EP1740197B1 (pl)
JP (3) JP2007534752A (pl)
AU (1) AU2005239985B2 (pl)
CA (1) CA2563505C (pl)
DK (1) DK1740197T3 (pl)
ES (1) ES2437569T3 (pl)
NO (1) NO340598B1 (pl)
PL (1) PL1740197T3 (pl)
PT (1) PT1740197E (pl)
WO (1) WO2005107786A1 (pl)

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AU2003215272B2 (en) * 2002-02-14 2008-04-03 The Board Of Trustees Of The Leland Stanford Junior University Enzyme treatment of foodstuffs for celiac sprue
US8143210B2 (en) * 2002-02-14 2012-03-27 The Board Of Trustees Of The Leland Stanford Junior University Enzyme treatment of foodstuffs for celiac sprue
US7462688B2 (en) * 2002-05-14 2008-12-09 The Board Of Trustees Of The Leland Stanford Junior University Peptides for diagnostic and therapeutic methods for celiac sprue
US7265093B2 (en) * 2002-05-14 2007-09-04 The Board Of Trustees Of The Leland Stanford Junior University Drug therapy for Celiac Sprue
AU2003234634A1 (en) * 2002-05-14 2003-12-02 Felix Hausch Drug therapy for celiac sprue
US7776545B2 (en) * 2002-11-20 2010-08-17 The Board Of Trustees Of The Leland Stanford Junior University Diagnostic method for Celiac Sprue
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US7579313B2 (en) * 2003-11-18 2009-08-25 The Board Of Trustees Of The Leland Stanford Junior University Transglutaminase inhibitors and methods of use thereof
US10105437B2 (en) 2004-04-28 2018-10-23 Btg International Limited Epitopes related to coeliac disease
AU2005237287B2 (en) 2004-04-28 2011-08-11 Btg International Limited Epitopes related to coeliac disease
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EP1949093A2 (en) * 2005-10-11 2008-07-30 Alvine Pharmaceuticals, Inc. Compositions and methods for enhanced gastrointestinal stability of oligopeptides and polypeptides
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WO2008115428A2 (en) * 2007-03-16 2008-09-25 The Board Of Trustees Of The Leland Stanford Junior University A scaleable manufacturing process for cysteine endoprotease b, isoform 2
WO2008115411A1 (en) * 2007-03-16 2008-09-25 The Board Of Trustees Of The Leland Stanford Junior University Combination enzyme therapy for digestion of dietary gluten
EP2229404A4 (en) * 2007-12-10 2011-03-09 Univ Leland Stanford Junior ENZYMATIC POLYTHERAPY FOR GASTRIC DIGESTION OF FOOD GLUTEN IN PATIENTS WITH CELIAC DISEASE
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HUE027237T2 (en) 2008-11-30 2016-10-28 Immusant Inc Compositions and methods for treatment of celiac disease
AU2010205890B2 (en) * 2009-01-15 2015-01-15 Glutagen Pty Ltd Compositions for the treatment of gluten intolerance and uses thereof
DE102009045268A1 (de) 2009-10-01 2011-04-07 Charité - Universitätsmedizin Berlin Neue Marker für die Diagnose von Zöliakie
US8685392B2 (en) 2009-10-07 2014-04-01 Trustees Of Boston University Rothia species glutamine endopeptidases and use thereof
EP2531521B1 (en) * 2010-02-02 2017-09-06 Amano Enzyme USA., Ltd. Use of proteases for gluten intolerance
CN103097513B (zh) * 2010-03-12 2018-01-30 热尔韦·达诺尼公司 用于乳糜泻的乳酸菌
US9598684B2 (en) 2010-07-07 2017-03-21 Trustees Of Boston University Rothia species gluten-degrading enzymes and uses thereof
CN107831318B (zh) * 2011-01-20 2021-06-18 西瑞斯实验室有限公司 检测谷蛋白敏感性和其区分于乳糜泻的方法和装置
WO2012135646A2 (en) * 2011-03-30 2012-10-04 Alvine Pharmaceuticals, Inc. Proteases for degrading gluten
WO2013016427A1 (en) 2011-07-25 2013-01-31 Alvine Pharmaceuticals, Inc. Methods and pharmaceutical compositions for treating celiac disease and gluten intolerance
CA2882502A1 (en) 2011-08-10 2013-02-14 University Of Washington Through Its Center For Commercialization Compositions and methods for treating celiac sprue disease
US20140219982A1 (en) * 2011-09-29 2014-08-07 Amano Enzyme Inc. Exogenous opioid peptide-degrading enzyme
ES2595500T3 (es) 2011-12-06 2016-12-30 Fondazione Istituto Insubrico Di Ricerca Per La Vita Nuevas proteasas que pueden hidrolizar péptidos y proteínas de gluten a un pH ácido, procedentes del actinomiceto Actinoallomurus
WO2014011662A2 (en) * 2012-07-09 2014-01-16 Alvine Pharmaceuticals, Inc. Acid stable prolyl endopeptidases for degrading gluten
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WO2015192211A1 (en) 2014-06-16 2015-12-23 Nepetx, Llc Compositions and methods for treating gluten intolerance and disorders arising therefrom
CA2962933A1 (en) 2014-09-29 2016-04-07 Immusant, Inc. Use of hla genetic status to assess or select treatment of celiac disease
FR3034307B1 (fr) 2015-04-03 2021-10-22 Univ Grenoble 1 Reacteur intestinal implantable
NZ737500A (en) 2015-06-08 2025-02-28 Univ Washington Compositions and methods for treating celiac sprue disease
US10857214B2 (en) 2015-12-16 2020-12-08 Codexis, Inc. Compositions and methods for treating gluten intolerance and disorders arising therefrom
US20190307860A1 (en) 2016-11-23 2019-10-10 Immunogenics Llc Latiglutenase (alv003) for use in the treatment of symptomatic celiac disease, gluten intolerance or gluten sensitivity
WO2020087017A1 (en) * 2018-10-26 2020-04-30 The Regents Of The University Of California Use of proteolytic enzymes to enhance protein bioavailability
KR102184812B1 (ko) * 2018-12-13 2020-11-30 대한민국 새찰쌀보리 추출물을 포함하는 골다공증 예방 또는 치료용 조성물
JP7390398B2 (ja) * 2019-04-02 2023-12-01 サミ－サビンサ グループ リミテッド グルテン不耐性の治療管理のための方法および組成物
JP2022542835A (ja) 2019-07-25 2022-10-07 ネミシス リミテッド 組換えエンドペプチダーゼを含む酵素組成物の製造方法
IT201900012942A1 (it) 2019-07-25 2021-01-25 Nemysis Ltd Metodo per la produzione di una composizione enzimatica comprendente una endopeptidasi ricombinante
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CN116004751B (zh) * 2022-12-13 2026-02-10 江南大学 一种利用生姜提取液和谷朊粉制备功能性肽的方法

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Also Published As

Publication number Publication date
AU2005239985A1 (en) 2005-11-17
EP1740197A1 (en) 2007-01-10
NO340598B1 (no) 2017-05-15
EP1740197A4 (en) 2009-09-16
CA2563505A1 (en) 2005-11-17
JP2015063554A (ja) 2015-04-09
DK1740197T3 (da) 2013-11-11
ES2437569T3 (es) 2014-01-13
EP1740197B1 (en) 2013-10-16
US20050249719A1 (en) 2005-11-10
WO2005107786A1 (en) 2005-11-17
JP2012092125A (ja) 2012-05-17
US7320788B2 (en) 2008-01-22
JP2007534752A (ja) 2007-11-29
AU2005239985B2 (en) 2010-08-12
PT1740197E (pt) 2013-12-02
CA2563505C (en) 2020-09-08
NO20065195L (no) 2007-01-18

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