DK178487D0 - Fremgangsmaade til fremstilling af human plasminogenaktivator - Google Patents

Fremgangsmaade til fremstilling af human plasminogenaktivator

Info

Publication number: DK178487D0
Authority: DK; Denmark
Prior art keywords: plasminogen activator; human plasminogen; manufacturing human; manufacturing; activator
Prior art date: 1986-04-09

Application number

DK178487A

Other languages

English (en)

Other versions

DK178487A (da

Inventor

Daniel Thomas Connolly

Joseph Feder

Nicholaos Konstantinos Harakas

Jon Peter Schaumann

Arthur John Wittwer

Original Assignee

Monsanto Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-04-09

Filing date

1987-04-08

Publication date

1987-04-08

1987-04-08 Application filed by Monsanto Co filed Critical Monsanto Co

1987-04-08 Publication of DK178487D0 publication Critical patent/DK178487D0/da

1987-10-10 Publication of DK178487A publication Critical patent/DK178487A/da

Links

101000605403 Homo sapiens Plasminogen Proteins 0.000 title 1
102000001938 Plasminogen Activators Human genes 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
238000000034 method Methods 0.000 title 1
229940127126 plasminogen activator Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6456—Plasminogen activators
- C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21069—Protein C activated (3.4.21.69)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Biomedical Technology (AREA)
Medicinal Chemistry (AREA)
General Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Biotechnology (AREA)
Microbiology (AREA)
Materials Engineering (AREA)
Polymers & Plastics (AREA)
Chemical Kinetics & Catalysis (AREA)
Analytical Chemistry (AREA)
Biophysics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Cell Biology (AREA)
Enzymes And Modification Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Peptides Or Proteins (AREA)

DK178487A 1986-04-09 1987-04-08 Fremgangsmaade til fremstilling af human plasminogenaktivator DK178487A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/849,933 US5132214A (en)	1986-04-09	1986-04-09	Large scale production of plasminogen activator from normal human colon cells

Publications (2)

Publication Number	Publication Date
DK178487D0 true DK178487D0 (da)	1987-04-08
DK178487A DK178487A (da)	1987-10-10

Family

ID=25306874

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK178487A DK178487A (da)	1986-04-09	1987-04-08	Fremgangsmaade til fremstilling af human plasminogenaktivator

Country Status (13)

Country	Link
US (1)	US5132214A (da)
EP (1)	EP0241448A3 (da)
JP (1)	JPS6322187A (da)
KR (1)	KR900002345B1 (da)
AU (1)	AU590918B2 (da)
CA (1)	CA1282726C (da)
DK (1)	DK178487A (da)
ES (1)	ES2002685A4 (da)
FI (1)	FI871536L (da)
NO (1)	NO168055C (da)
NZ (1)	NZ219920A (da)
PT (1)	PT84637B (da)
ZA (1)	ZA872530B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4960702A (en) *	1985-09-06	1990-10-02	Codon	Methods for recovery of tissue plasminogen activator
AU2921289A (en) *	1987-12-09	1989-07-19	Invitron Corporation	Human cell life extension
US4957863A (en) *	1988-01-26	1990-09-18	Monsanto Company	Method of increasing yield of t-PA in cell culture
US5089409A (en) *	1989-09-28	1992-02-18	Monsanto Company	Method of increasing specific activity of t-pa
DE3942142A1 (de) *	1989-12-20	1991-06-27	Boehringer Mannheim Gmbh	Stabilisierung von glykosyliertem t-pa
TW200821026A (en) *	2006-09-08	2008-05-16	Wyeth Corp	Arginine wash in protein purification using affinity chromatography

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3904480A (en) *	1972-10-24	1975-09-09	Lilly Co Eli	Enhanced production of plasminogen activator
US4190708A (en) *	1978-05-24	1980-02-26	Monsanto Company	Production of urokinase
DE3015699C2 (de) *	1979-04-26	1982-07-15	Asahi Kasei Kogyo K.K., Osaka	Herstellung eines Plasminogen-Aktivators
NL8003402A (nl) *	1980-06-11	1982-01-04	Leuven Res & Dev Vzw	Nieuwe plasminogeen-activator en farmaceutisch preparaat met trombolytische werking.
US4335215A (en) *	1980-08-27	1982-06-15	Monsanto Company	Method of growing anchorage-dependent cells
IL68561A (en) *	1982-05-05	1991-01-31	Genentech Inc	Preparation of polypeptide with human tissue plasminogen activator function,processes for making it,and dna and transformed cell intermediates thereof
JPS5951220A (ja) *	1982-08-02	1984-03-24	Asahi Chem Ind Co Ltd	新規なプラスミノ−ゲン・アクチベ−タ−およびその製法ならびにこれを含有する薬剤
US4537860A (en) *	1982-12-08	1985-08-27	Monsanto Company	Static cell culture maintenance system
IE56716B1 (en) *	1983-01-19	1991-11-20	Genentech Inc	Method for producing human tpa and expression vectors therefor
JPS59187779A (ja) *	1983-04-08	1984-10-24	Wakamoto Pharmaceut Co Ltd	ウロキナ−ゼ精製用吸着体
US4550080A (en) *	1984-06-05	1985-10-29	Asahi Kasei Kogyo Kabushiki Kaisha	Process for the preparation of a plasminogen activator
US4661453A (en) *	1984-06-19	1987-04-28	American Biogenetic Sciences, Inc.	Production of tissue plasminogen activator factor
US4751084A (en) *	1986-02-26	1988-06-14	Monsanto Company	Tissue plasminogen activator from normal human colon cells

1986
- 1986-04-09 US US06/849,933 patent/US5132214A/en not_active Expired - Lifetime
1987
- 1987-04-08 NZ NZ219920A patent/NZ219920A/xx unknown
- 1987-04-08 DK DK178487A patent/DK178487A/da not_active Application Discontinuation
- 1987-04-08 AU AU71302/87A patent/AU590918B2/en not_active Ceased
- 1987-04-08 CA CA000534196A patent/CA1282726C/en not_active Expired - Lifetime
- 1987-04-08 PT PT84637A patent/PT84637B/pt not_active IP Right Cessation
- 1987-04-08 KR KR1019870003340A patent/KR900002345B1/ko not_active Expired
- 1987-04-08 ZA ZA872530A patent/ZA872530B/xx unknown
- 1987-04-08 ES ES87870047T patent/ES2002685A4/es active Pending
- 1987-04-08 EP EP87870047A patent/EP0241448A3/en not_active Withdrawn
- 1987-04-08 JP JP62086751A patent/JPS6322187A/ja active Pending
- 1987-04-08 FI FI871536A patent/FI871536L/fi not_active Application Discontinuation
- 1987-04-08 NO NO871477A patent/NO168055C/no unknown

Also Published As

Publication number	Publication date
PT84637A (en)	1987-05-01
NO168055B (no)	1991-09-30
FI871536A7 (fi)	1987-10-10
NO168055C (no)	1992-01-08
ZA872530B (en)	1988-01-27
FI871536A0 (fi)	1987-04-08
AU590918B2 (en)	1989-11-23
EP0241448A2 (en)	1987-10-14
PT84637B (pt)	1989-11-30
NO871477D0 (no)	1987-04-08
DK178487A (da)	1987-10-10
US5132214A (en)	1992-07-21
KR900002345B1 (ko)	1990-04-12
AU7130287A (en)	1987-10-15
NO871477L (no)	1987-10-12
KR870010182A (ko)	1987-11-30
JPS6322187A (ja)	1988-01-29
ES2002685A4 (es)	1988-10-01
CA1282726C (en)	1991-04-09
NZ219920A (en)	1989-08-29
EP0241448A3 (en)	1988-01-07
FI871536L (fi)	1987-10-10

Legal Events

Date	Code	Title	Description
1993-12-27	AHB	Application shelved due to non-payment

Publication	Publication Date	Title
DK618387D0 (da)	1987-11-25	Fremgangsmaade til sterilisering
DK238988D0 (da)	1988-05-03	Fremgangsmaade til fremstilling af 4-acyloxy-3-hydroxyethyl-azetidinoner
FI874593L (fi)	1988-04-21	Menetelmä kinapriilin stabiloimiseksi
FI872526L (fi)	1987-12-07	Menetelmä biologisesti aktiivisen plasminogeeniaktivaattorin tuottamiseksi
DK96787D0 (da)	1987-02-25	Human vaevs-plasminogenaktivator
DK559387D0 (da)	1987-10-26	Fremgangsmaade og mellemprodukt til fremstilling af 3-pyrrolidinoler
DK418487D0 (da)	1987-08-11	Fremgangsmaade til oprensning af vaevsplasminogenaktivator
DK223587A (da)	1987-11-04	Fremgangsmaade til fremstilling af azopigmenter
KR880004732A (ko)	1988-06-07	본딩방법
DK14589A (da)	1989-07-16	Fremgangsmaade til fremstilling af 1-alkyl-5-nitroimidazoler
DK178487A (da)	1987-10-10	Fremgangsmaade til fremstilling af human plasminogenaktivator
DK223487A (da)	1987-11-04	Fremgangsmaade til fremstilling af azopigmenter
DK369686D0 (da)	1986-08-01	Fremgangsmaade til oprensning af vaevsplasminogenaktivator
DK78388D0 (da)	1988-02-16	Fremgangsmaade til fremstilling af 4-acetoxy-3-hydroxyethyl-azetidinon
DK443487A (da)	1988-02-29	Multistik og fremgangsmaade og maskine til fremstilling af samme
DK140288D0 (da)	1988-03-15	Fremgangsmaade til oprensning af plasminogenaktivator
DK190187D0 (da)	1987-04-13	Fremgangsmaade til fremstilling af n-aminophthalimid
DK94487D0 (da)	1987-02-24	Fremgangsmaade til fremstilling af encainid
KR870019230U (ko)	1987-12-28	포커스 블럭
DK143389D0 (da)	1989-03-22	Fremgangsmaade til fremstilling af 20-deoxotylosin
DK38884D0 (da)	1984-01-27	Fremgangsmade til fremstilling af humant insulin
DK500688D0 (da)	1988-09-09	Fremgangsmaade til fremstilling af masolin
DK319289D0 (da)	1989-06-27	Fremgangsmaade til fremstilling af raastaal
DK481184A (da)	1984-10-08	Fremgangsmaade til fremstilling af humant insulin
DK55183D0 (da)	1983-02-09	Fremgangsmade til fremstilling af human insulin