DK1851322T3 - Fremgangsmåde til enantioselektiv enzymatisk reduktion af ketoforbindelser - Google Patents

Fremgangsmåde til enantioselektiv enzymatisk reduktion af ketoforbindelser

Info

Publication number
DK1851322T3
DK1851322T3 DK06723073.0T DK06723073T DK1851322T3 DK 1851322 T3 DK1851322 T3 DK 1851322T3 DK 06723073 T DK06723073 T DK 06723073T DK 1851322 T3 DK1851322 T3 DK 1851322T3
Authority
DK
Denmark
Prior art keywords
enzymatic reduction
keto compounds
enantioselective enzymatic
halo
acid esters
Prior art date
Application number
DK06723073.0T
Other languages
English (en)
Inventor
Anke Tschentscher
Antje Gupta
Maria Bobkova
Original Assignee
Iep Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36293601&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1851322(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Iep Gmbh filed Critical Iep Gmbh
Application granted granted Critical
Publication of DK1851322T3 publication Critical patent/DK1851322T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
DK06723073.0T 2005-02-21 2006-02-21 Fremgangsmåde til enantioselektiv enzymatisk reduktion af ketoforbindelser DK1851322T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT0028505A AT501496B1 (de) 2005-02-21 2005-02-21 Verfahren zur enantioselektiven enzymatischen reduktion von ketoverbindungen
PCT/EP2006/001562 WO2006087235A1 (de) 2005-02-21 2006-02-21 Verfahren zur enantioselektiven enzymatischen reduktion von ketoverbindungen

Publications (1)

Publication Number Publication Date
DK1851322T3 true DK1851322T3 (da) 2010-02-08

Family

ID=36293601

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06723073.0T DK1851322T3 (da) 2005-02-21 2006-02-21 Fremgangsmåde til enantioselektiv enzymatisk reduktion af ketoforbindelser

Country Status (13)

Country Link
US (1) US8158406B2 (da)
EP (1) EP1851322B1 (da)
JP (1) JP2008529542A (da)
KR (1) KR101275061B1 (da)
CN (1) CN101128594B (da)
AT (2) AT501496B1 (da)
CA (1) CA2597648C (da)
DE (1) DE502006005179D1 (da)
DK (1) DK1851322T3 (da)
ES (1) ES2335229T3 (da)
PL (1) PL1851322T3 (da)
PT (1) PT1851322E (da)
WO (1) WO2006087235A1 (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT501928B1 (de) * 2004-10-27 2010-09-15 Iep Gmbh Verfahren zur herstellung von chiralen alkoholen
DE102005038606A1 (de) * 2005-08-16 2007-03-01 Consortium für elektrochemische Industrie GmbH Verfahren zur enzymatischen Herstellung von chiralen 1-acylierten 1,2-Diolen
WO2008042876A2 (en) 2006-10-02 2008-04-10 Codexis, Inc. Compositions and methods for producing stereoisomerically pure statins and synthetic intermediates therefor
US9273332B2 (en) * 2006-10-12 2016-03-01 Kaneka Corporation Method for production of L-amino acid
AT504542B1 (de) 2006-12-07 2008-09-15 Iep Gmbh Verfahren zur enantioselektiven enzymatischen reduktion von secodionderivaten
EP2198018B1 (en) 2007-09-13 2013-11-20 Codexis, Inc. Ketoreductase polypeptides for the reduction of acetophenones
TWI601825B (zh) * 2007-09-27 2017-10-11 Ｉｅｐ有限公司 對映異構選擇性酶催化還原中間產物之方法
EP2226386A1 (de) * 2009-03-05 2010-09-08 IEP GmbH Verfahren zur stereoselektiven enzymatischen Reduktion von Ketoverbindungen
PL2445890T3 (pl) * 2009-06-22 2016-02-29 Sk Biopharmaceuticals Co Ltd Sposób wytwarzania estru (R)-1-arylo-2-tetrazoliloetylowego kwasu karbaminowego
US8404461B2 (en) 2009-10-15 2013-03-26 SK Biopharmaceutical Co. Ltd. Method for preparation of carbamic acid (R)-1-aryl-2-tetrazolyl-ethyl ester
CN113528588A (zh) * 2021-06-15 2021-10-22 海南卓科制药有限公司 一种左卡尼汀的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2536075B1 (fr) * 1982-11-17 1985-07-05 Adir Nouveaux derives de la nitrosouree, leur procede de preparation et les compositions pharmaceutiques les renfermant
EP0349204A3 (en) * 1988-06-28 1991-08-07 Bend Research, Inc. Use and regeneration of reagents using coupled reactions and permselective barriers
US5385833A (en) * 1992-02-26 1995-01-31 The Scripps Research Institute Pseudomonas sp. ATCC No. 49794 alcohol dehydrogenase
DE19610984A1 (de) 1996-03-21 1997-09-25 Boehringer Mannheim Gmbh Alkohol-Dehydrogenase und deren Verwendung zur enzymatischen Herstellung chiraler Hydroxyverbindungen
TWI275645B (en) * 2000-02-16 2007-03-11 Daicel Chemical Industries Ltd. (R)-2-octanol dehydrogenases, methods for producing the enzymes, DNA encoding the enzymes, and methods for producing alcohols using the enzymes
DE10119274A1 (de) * 2001-04-20 2002-10-31 Juelich Enzyme Products Gmbh Enzymatisches Verfahren zur enantioselektiven Reduktion von Ketoverbindungen
JP2005520517A (ja) 2002-03-18 2005-07-14 チバ　スペシャルティ　ケミカルズ　ホールディング　インコーポレーテッド 高い溶媒および温度安定性を有するアルコールデヒドロゲナーゼ
DE10327454A1 (de) * 2003-06-18 2005-01-20 Juelich Enzyme Products Gmbh Oxidoreduktase aus Pichia capsulata

Also Published As

Publication number Publication date
CN101128594A (zh) 2008-02-20
PL1851322T3 (pl) 2010-03-31
CA2597648A1 (en) 2006-08-24
US8158406B2 (en) 2012-04-17
EP1851322A1 (de) 2007-11-07
WO2006087235A1 (de) 2006-08-24
KR101275061B1 (ko) 2013-06-14
KR20070115984A (ko) 2007-12-06
CN101128594B (zh) 2012-12-26
JP2008529542A (ja) 2008-08-07
PT1851322E (pt) 2010-01-20
ES2335229T3 (es) 2010-03-23
US20080153140A1 (en) 2008-06-26
EP1851322B1 (de) 2009-10-21
ATE446374T1 (de) 2009-11-15
AT501496A1 (de) 2006-09-15
CA2597648C (en) 2014-09-09
AT501496B1 (de) 2007-03-15
DE502006005179D1 (de) 2009-12-03

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