DK185689A - Avermectin-derivater, deres anvendelse til fremstilling af ectoparasiticide, insecticide, acaricide eller anthelmintiske laegemidler, praeparater indeholdende forbindelserne og fremgangsmaade til bekaempelse af skadedyr i afgroeder - Google Patents

Avermectin-derivater, deres anvendelse til fremstilling af ectoparasiticide, insecticide, acaricide eller anthelmintiske laegemidler, praeparater indeholdende forbindelserne og fremgangsmaade til bekaempelse af skadedyr i afgroeder

Info

Publication number: DK185689A
Authority: DK; Denmark
Prior art keywords: ectoparasiticide; medicinals; acaricide; anthelmintic; insecticide
Prior art date: 1988-04-19

Application number

DK185689A

Other languages

English (en)

Other versions

DK168766B1 (da

DK185689D0 (da

Inventor

Bernard Joseph Banks

Michael John Witty

Original Assignee

Pfizer Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-04-19

Filing date

1989-04-18

Publication date

1989-12-27

1989-04-18 Application filed by Pfizer Ltd filed Critical Pfizer Ltd

1989-04-18 Publication of DK185689D0 publication Critical patent/DK185689D0/da

1989-12-27 Publication of DK185689A publication Critical patent/DK185689A/da

1994-06-06 Application granted granted Critical

1994-06-06 Publication of DK168766B1 publication Critical patent/DK168766B1/da

Links

RRZXIRBKKLTSOM-XPNPUAGNSA-N avermectin B1a Chemical class C1=C[C@H](C)[C@@H]([C@@H](C)CC)O[C@]11O[C@H](C\C=C(C)\[C@@H](O[C@@H]2O[C@@H](C)[C@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](OC)C3)[C@@H](OC)C2)[C@@H](C)\C=C\C=C/2[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\2)O)C[C@H]4C1 RRZXIRBKKLTSOM-XPNPUAGNSA-N 0.000 title abstract 2
238000002360 preparation method Methods 0.000 title 2
RFEJUZJILGIRHQ-XRIOVQLTSA-N 2,3-dihydroxybutanedioic acid;3-[(2s)-1-methylpyrrolidin-2-yl]pyridine Chemical compound OC(=O)C(O)C(O)C(O)=O.OC(=O)C(O)C(O)C(O)=O.CN1CCC[C@H]1C1=CC=CN=C1 RFEJUZJILGIRHQ-XRIOVQLTSA-N 0.000 title 1
230000000895 acaricidal effect Effects 0.000 title 1
239000000642 acaricide Substances 0.000 title 1
230000000507 anthelmentic effect Effects 0.000 title 1
150000001875 compounds Chemical class 0.000 title 1
239000013057 ectoparasiticide Substances 0.000 title 1
239000002917 insecticide Substances 0.000 title 1
238000000034 method Methods 0.000 title 1
125000004432 carbon atom Chemical group C* 0.000 abstract 4
229910052799 carbon Inorganic materials 0.000 abstract 3
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
125000006527 (C1-C5) alkyl group Chemical group 0.000 abstract 1
125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 1
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
DHKHKXVYLBGOIT-UHFFFAOYSA-N acetaldehyde Diethyl Acetal Natural products CCOC(C)OCC DHKHKXVYLBGOIT-UHFFFAOYSA-N 0.000 abstract 1
150000001241 acetals Chemical class 0.000 abstract 1
230000002141 anti-parasite Effects 0.000 abstract 1
239000003096 antiparasitic agent Substances 0.000 abstract 1
229940125687 antiparasitic agent Drugs 0.000 abstract 1
125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
125000000466 oxiranyl group Chemical group 0.000 abstract 1
125000004430 oxygen atom Chemical group O* 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics

Landscapes

Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Plant Pathology (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Environmental Sciences (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Agronomy & Crop Science (AREA)
Pest Control & Pesticides (AREA)
Veterinary Medicine (AREA)
Dentistry (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Tropical Medicine & Parasitology (AREA)
Public Health (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Cephalosporin Compounds (AREA)

DK185689A 1988-04-19 1989-04-18 Avermectin-derivater, forbindelserne til anvendelse inden for veterinær medicin, præparater indeholdende forbindelserne, deres anvendelse til fremstilling af ectoparasitcide, insecticide, acaricide eller anthelmintiske lægemidler, og ikke-terapeutisk fremgangsmåde til bekæmpelse af skadedyr i afgrøder DK168766B1 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB888809232A GB8809232D0 (en)	1988-04-19	1988-04-19	Antiparasitic agents
GB8809232		1988-04-19

Publications (3)

Publication Number	Publication Date
DK185689D0 DK185689D0 (da)	1989-04-18
DK185689A true DK185689A (da)	1989-12-27
DK168766B1 DK168766B1 (da)	1994-06-06

Family

ID=10635447

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK185689A DK168766B1 (da)	1988-04-19	1989-04-18	Avermectin-derivater, forbindelserne til anvendelse inden for veterinær medicin, præparater indeholdende forbindelserne, deres anvendelse til fremstilling af ectoparasitcide, insecticide, acaricide eller anthelmintiske lægemidler, og ikke-terapeutisk fremgangsmåde til bekæmpelse af skadedyr i afgrøder

Country Status (12)

Country	Link
US (1)	US4927918A (da)
EP (1)	EP0340932B1 (da)
JP (1)	JPH0684395B2 (da)
AT (1)	ATE117312T1 (da)
CA (1)	CA1330795C (da)
DE (1)	DE68920623T2 (da)
DK (1)	DK168766B1 (da)
ES (1)	ES2066846T3 (da)
GB (1)	GB8809232D0 (da)
GR (1)	GR3015306T3 (da)
IE (1)	IE65954B1 (da)
PT (1)	PT90291B (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ233680A (en) *	1989-05-17	1995-02-24	Beecham Group Plc	Avermectins and milbemycins and compositions thereof
US5055454A (en) *	1989-10-30	1991-10-08	Merck & Co., Inc.	13-epi-avermectin derivatives useful as antiparasitic agents
GB9205007D0 (en) *	1992-03-07	1992-04-22	Pfizer Ltd	Antiparasitic agents
US6265571B1 (en)	1999-07-12	2001-07-24	Magellan Laboratories, Inc.	Purification process for anti-parasitic fermentation product

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4666937A (en) *	1985-03-04	1987-05-19	Merck & Co., Inc.	Avermectin bioconversion products
ES8800986A1 (es) *	1985-07-27	1987-12-01	Pfizer	Un procedimiento para la produccion de un nuevo derivado de avermectina
NZ216908A (en) *	1985-07-29	1989-06-28	Merck & Co Inc	Avermectin derivatives
GB8606108D0 (en) *	1986-03-12	1986-04-16	Glaxo Group Ltd	Chemical compounds
EP0284176B1 (en) *	1987-01-23	1993-08-25	Pfizer Inc.	Process for production of avermectins and cultures therefor

1988
- 1988-04-19 GB GB888809232A patent/GB8809232D0/en active Pending
1989
- 1989-04-11 US US07/336,400 patent/US4927918A/en not_active Expired - Lifetime
- 1989-04-14 DE DE68920623T patent/DE68920623T2/de not_active Expired - Fee Related
- 1989-04-14 AT AT89303723T patent/ATE117312T1/de not_active IP Right Cessation
- 1989-04-14 ES ES89303723T patent/ES2066846T3/es not_active Expired - Lifetime
- 1989-04-14 EP EP89303723A patent/EP0340932B1/en not_active Expired - Lifetime
- 1989-04-17 PT PT90291A patent/PT90291B/pt not_active IP Right Cessation
- 1989-04-17 CA CA000596834A patent/CA1330795C/en not_active Expired - Fee Related
- 1989-04-18 IE IE124189A patent/IE65954B1/en not_active IP Right Cessation
- 1989-04-18 DK DK185689A patent/DK168766B1/da not_active IP Right Cessation
- 1989-04-19 JP JP1099920A patent/JPH0684395B2/ja not_active Expired - Fee Related
1995
- 1995-03-03 GR GR950400484T patent/GR3015306T3/el unknown

Also Published As

Publication number	Publication date
DK168766B1 (da)	1994-06-06
PT90291A (pt)	1989-11-10
EP0340932A3 (en)	1991-03-13
ES2066846T3 (es)	1995-03-16
DE68920623T2 (de)	1995-05-18
GR3015306T3 (en)	1995-06-30
PT90291B (pt)	1994-07-29
ATE117312T1 (de)	1995-02-15
EP0340932A2 (en)	1989-11-08
JPH01311097A (ja)	1989-12-15
IE891241L (en)	1989-10-19
DK185689D0 (da)	1989-04-18
GB8809232D0 (en)	1988-05-25
IE65954B1 (en)	1995-11-29
DE68920623D1 (de)	1995-03-02
US4927918A (en)	1990-05-22
JPH0684395B2 (ja)	1994-10-26
CA1330795C (en)	1994-07-19
EP0340932B1 (en)	1995-01-18

Legal Events

Date	Code	Title	Description
1994-06-06	B1	Patent granted (law 1993)
2004-11-29	PBP	Patent lapsed	Country of ref document: DK

Publication	Publication Date	Title
AU532187B2 (en)	1983-09-22	Sugar derivatives of c-076 compounds
DK328579A (da)	1980-02-05	Alkylderivater af c-076 forbindelser og fremgangsmaade til fremstilling deraf
UA6345A1 (uk)	1994-12-29	Спосіб одержання похідного авермектіна
IE781964L (en)	1979-04-03	Derivatives of c-076 compounds
AU1157792A (en)	1992-08-17	Bridged cyclic ketal derivatives
DK185689D0 (da)	1989-04-18	Avermectin-derivater, deres anvendelse til fremstilling af ectoparasiticide, insecticide, acaricide eller anthelmintiske laegemidler, praeparater indeholdende forbindelserne og fremgangsmaade til bekaempelse af skadedyr i afgroeder
DE3853804D1 (de)	1995-06-22	Zearalanol-Derivate mit anabolytischer Wirkung.
DE68928745D1 (de)	1998-08-27	Makrolid-Derivate
ATE71105T1 (de)	1992-01-15	4-substituierte anthracyclinone und anthracyclinonglycoside und ihre herstellung.
DK75291A (da)	1991-06-20	Hidtil ukendte 4-substituerede anthracyclinoner og anthracyclinglycosider samt fremgangsmaade til fremstilling deraf
ES8506011A1 (es)	1985-06-16	Procedimiento para la obtencion de un derivado de tetrahidrobenzotiazol
DK311585A (da)	1986-01-10	Monobasiske disobutamidderivater og farmaceutisk acceptable syreadditionssalte deraf samt fremgangsmaade til deres fremstilling
DE3787986D1 (de)	1993-12-09	Macrolid-Derivate.
DE3851189D1 (de)	1994-09-29	Makrolid-Derivate.
PT81255A (en)	1985-11-01	Process for the preparation of 2-pyridine-thiol derivatives and pharmaceutical compositions containing them
SE8200679L (sv)	1982-09-22	1-bensyl-4-(4-(2-pyrimidinylamino) bensyl 1-2,3-dioxopiperazinderivat, salter derav, forfarande for framstellning derav och karcinostatiska medel der de ingar
DK0485894T3 (da)	1999-09-20	Fremgangsmåde til fremstilling af semisyntetiske diastereomerrene N-glycidyl-anthracycliner