ES2066846T3 - Agentes antiparasitarios relacionados con las avermectinas. - Google Patents

Agentes antiparasitarios relacionados con las avermectinas.

Info

Publication number
ES2066846T3
ES2066846T3 ES89303723T ES89303723T ES2066846T3 ES 2066846 T3 ES2066846 T3 ES 2066846T3 ES 89303723 T ES89303723 T ES 89303723T ES 89303723 T ES89303723 T ES 89303723T ES 2066846 T3 ES2066846 T3 ES 2066846T3
Authority
ES
Spain
Prior art keywords
double bond
carbon atom
oxo
absent
avermectins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89303723T
Other languages
English (en)
Inventor
Bernard Joseph Dr Banks
Michael John Dr Witty
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Ltd Great Britain
Pfizer Inc
Original Assignee
Pfizer Ltd Great Britain
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Ltd Great Britain, Pfizer Inc filed Critical Pfizer Ltd Great Britain
Application granted granted Critical
Publication of ES2066846T3 publication Critical patent/ES2066846T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Public Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Cephalosporin Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

LA INVENCION SE REFIERE A AGENTES ANTIPARASITARIOS QUE COMPRENDEN DERIVADOS DE AVERMECTINA DE FORMULA(I) EN LA QUE LA LINEA DISCONTINUA ENTRE LAS POSICIONES 22 Y 23 ES UN DOBLE ENLACE OPCIONAL Y EN LA QUE R1 ES H O OH Y EL DOBLE ENLACE ESTA AUSENTE, O BIEN EL DOBLE ENLACE ESTA PRESENTE Y R1 ESTA AUSENTE; R2 ES UN GRUPO ALQUILO DE 1 A 6 C SUSTITUIDO POR UN GRUPO OXO O UNO O MAS GRUPOS OH O POR UN SOLO ATOMO DE O SOBRE DOS ATOMOS DE C ADYACENTES PARA FORMAR UN ANILLO OXIRANO, O R2 ES UN GRUPO ALQUILO DE 1 A 5 C SUSTITUIDO POR UN GRUPO (ALCOXI DE 1 A 6 C) - CARBONILO, ESTANDO LOS SUSTITUYENTES SOBRE R2 UNIDOS A UN ATOMO DE C TERMINAL, A UN ATOMO DE C ADYACENTE A ESTE O A AMBOS; Y R3 ES H O CH3; O CUANDO R2 ESTA SUSTITUIDO POR UN GRUPO OXO) A UN DERIVADO (ALQUIL DE 1 A 4 C) - ACETAL O CETAL DE LOS INDICADOS COMPUESTOS.
ES89303723T 1988-04-19 1989-04-14 Agentes antiparasitarios relacionados con las avermectinas. Expired - Lifetime ES2066846T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888809232A GB8809232D0 (en) 1988-04-19 1988-04-19 Antiparasitic agents

Publications (1)

Publication Number Publication Date
ES2066846T3 true ES2066846T3 (es) 1995-03-16

Family

ID=10635447

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89303723T Expired - Lifetime ES2066846T3 (es) 1988-04-19 1989-04-14 Agentes antiparasitarios relacionados con las avermectinas.

Country Status (12)

Country Link
US (1) US4927918A (es)
EP (1) EP0340932B1 (es)
JP (1) JPH0684395B2 (es)
AT (1) ATE117312T1 (es)
CA (1) CA1330795C (es)
DE (1) DE68920623T2 (es)
DK (1) DK168766B1 (es)
ES (1) ES2066846T3 (es)
GB (1) GB8809232D0 (es)
GR (1) GR3015306T3 (es)
IE (1) IE65954B1 (es)
PT (1) PT90291B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ233680A (en) * 1989-05-17 1995-02-24 Beecham Group Plc Avermectins and milbemycins and compositions thereof
US5055454A (en) * 1989-10-30 1991-10-08 Merck & Co., Inc. 13-epi-avermectin derivatives useful as antiparasitic agents
GB9205007D0 (en) * 1992-03-07 1992-04-22 Pfizer Ltd Antiparasitic agents
US6265571B1 (en) 1999-07-12 2001-07-24 Magellan Laboratories, Inc. Purification process for anti-parasitic fermentation product

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4666937A (en) * 1985-03-04 1987-05-19 Merck & Co., Inc. Avermectin bioconversion products
ES8800986A1 (es) * 1985-07-27 1987-12-01 Pfizer Un procedimiento para la produccion de un nuevo derivado de avermectina
NZ216908A (en) * 1985-07-29 1989-06-28 Merck & Co Inc Avermectin derivatives
GB8606108D0 (en) * 1986-03-12 1986-04-16 Glaxo Group Ltd Chemical compounds
DE3883408T2 (de) * 1987-01-23 1993-12-09 Pfizer Verfahren zur Herstellung von Avermectinen und die verwendeten Kulturen.

Also Published As

Publication number Publication date
DK185689A (da) 1989-12-27
IE891241L (en) 1989-10-19
GB8809232D0 (en) 1988-05-25
ATE117312T1 (de) 1995-02-15
GR3015306T3 (en) 1995-06-30
EP0340932A2 (en) 1989-11-08
IE65954B1 (en) 1995-11-29
JPH0684395B2 (ja) 1994-10-26
DE68920623T2 (de) 1995-05-18
DE68920623D1 (de) 1995-03-02
PT90291A (pt) 1989-11-10
EP0340932B1 (en) 1995-01-18
JPH01311097A (ja) 1989-12-15
DK168766B1 (da) 1994-06-06
US4927918A (en) 1990-05-22
CA1330795C (en) 1994-07-19
DK185689D0 (da) 1989-04-18
EP0340932A3 (en) 1991-03-13
PT90291B (pt) 1994-07-29

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