DK189983D0 - Fremgangsmade til fremstilling af ergolinderivater - Google Patents

Fremgangsmade til fremstilling af ergolinderivater

Info

Publication number: DK189983D0
Authority: DK; Denmark
Prior art keywords: procedure; preparation; ergoline derivatives; ergoline; derivatives
Prior art date: 1982-04-30

Application number

DK1899/83A

Other languages

English (en)

Other versions

DK164058C (da

DK164058B (da

DK189983A (da

Inventor

Luigi Bernardi

Aldemio Temperilli

Sergio Mantegani

Gabriella Traquandi

Patricia Salvati

Original Assignee

Erba Farmitalia

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-04-30

Filing date

1983-04-28

Publication date

1983-04-28

1983-04-28 Application filed by Erba Farmitalia filed Critical Erba Farmitalia

1983-04-28 Publication of DK189983D0 publication Critical patent/DK189983D0/da

1983-10-31 Publication of DK189983A publication Critical patent/DK189983A/da

1992-05-04 Publication of DK164058B publication Critical patent/DK164058B/da

1992-10-12 Application granted granted Critical

1992-10-12 Publication of DK164058C publication Critical patent/DK164058C/da

Links

AWFDCTXCTHGORH-HGHGUNKESA-N 6-[4-[(6ar,9r,10ar)-5-bromo-7-methyl-6,6a,8,9,10,10a-hexahydro-4h-indolo[4,3-fg]quinoline-9-carbonyl]piperazin-1-yl]-1-methylpyridin-2-one Chemical class O=C([C@H]1CN([C@H]2[C@@H](C=3C=CC=C4NC(Br)=C(C=34)C2)C1)C)N(CC1)CCN1C1=CC=CC(=O)N1C AWFDCTXCTHGORH-HGHGUNKESA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Cardiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Heart & Thoracic Surgery (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

DK189983A 1982-04-30 1983-04-28 Analogifremgangsmaade til fremstilling af ergolinderivater DK164058C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB8212653		1982-04-30
GB8212653		1982-04-30

Publications (4)

Publication Number	Publication Date
DK189983D0 true DK189983D0 (da)	1983-04-28
DK189983A DK189983A (da)	1983-10-31
DK164058B DK164058B (da)	1992-05-04
DK164058C DK164058C (da)	1992-10-12

Family

ID=10530108

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK189983A DK164058C (da)	1982-04-30	1983-04-28	Analogifremgangsmaade til fremstilling af ergolinderivater

Country Status (21)

Country	Link
US (1)	US4657914A (da)
JP (1)	JPS58194884A (da)
AT (1)	AT385035B (da)
AU (1)	AU553851B2 (da)
BE (1)	BE896609A (da)
CA (1)	CA1210389A (da)
CH (1)	CH654305A5 (da)
CS (1)	CS236874B2 (da)
DE (1)	DE3314878A1 (da)
DK (1)	DK164058C (da)
FI (1)	FI73996C (da)
FR (1)	FR2526022B1 (da)
GB (1)	GB2120242A (da)
GR (1)	GR78842B (da)
HU (1)	HU193527B (da)
IE (1)	IE53950B1 (da)
IL (1)	IL68496A (da)
IT (1)	IT1215630B (da)
NL (1)	NL191709C (da)
SE (1)	SE460967B (da)
ZA (1)	ZA833008B (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8714767D0 (en) *	1987-06-24	1987-07-29	Erba Farmitalia	Egoline derivatives
HU190105B (en) *	1983-06-03	1986-08-28	Gyogyszerkutato Intezet	Process for production of pirazolyl-methyl-ergolin- derivatives and their acid additional salts
GB2173189B (en) *	1985-02-21	1988-04-27	Maruko Pharmaceutical Co	Ergoline derivatives and salts thereof and pharmaceutical compositions thereof
GB8702364D0 (en) *	1987-02-03	1987-03-11	Erba Farmitalia	Ergolinyl heterocycles
EP2566333A4 (en) *	2010-05-07	2014-04-02	Univ Leland Stanford Junior	IDENTIFICATION OF STABILIZERS OF MULTIMEDER PROTEINS
US20160045609A1 (en)	2014-08-14	2016-02-18	Mamoun M. Alhamadsheh	Conjugation of pharmaceutically active agents with transthyretin ligands through adjustable linkers to increase serum half-life
EP3582773A4 (en)	2017-02-17	2021-03-10	Eidos Therapeutics, Inc.	PROCESS FOR THE MANUFACTURING OF AG-10, ITS INTERMEDIATES AND SALTS THEREOF
WO2019183463A1 (en)	2018-03-23	2019-09-26	Eidos Therapeutics, Inc.	Methods of treating ttr amyloidosis using ag10
LT3836920T (lt)	2018-08-17	2026-01-26	Eidos Therapeutics, Inc.	Ag10 farmacinės formos

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3238211A (en) *		1966-03-01		Derhvatives of g-methyl and i,g-dimethyl ergolhne
US3296071A (en) *	1963-05-31	1967-01-03	Upjohn Co	Reducing blood sugar with 3-alkyl-5-alkoxymethylisoxazole
CH507248A (de) *	1967-03-16	1971-05-15	Spofa Vereinigte Pharma Werke	Verfahren zur Herstellung von D-6-Methylergolin(I)ylessigsäure
US3957785A (en) *	1971-12-02	1976-05-18	Societa' Farmaceutici Italia S.P.A.	Bβ-Pyrimidino-aminomethyl-10α-ergoline and 10α-methoxyergoline derivatives
CH563376A5 (da) *	1972-06-29	1975-06-30	Lonza Ag
US3996228A (en) *	1973-12-21	1976-12-07	Societa' Farmaceutici Italia S.P.A.	Pyrimidinoaminoethyl ergoline derivatives
NL7416120A (nl) *	1973-12-21	1975-06-24	Farmaceutici Italia	Werkwijze voor het bereiden van pyrimidinoami- nomethylergolinederivaten.
IE41533B1 (en) *	1974-03-14	1980-01-30	Sandoz Ltd	Thiomethyl ergolene derivatives
US4147789A (en) *	1974-03-14	1979-04-03	Sandoz Ltd.	6-Methyl-8-thiomethyl-ergolene derivatives
CS171480B1 (da) *	1974-03-19	1976-10-29
CS177530B1 (en) *	1974-07-19	1977-07-29	Miroslav Semonsky	New nbeta-substituted derivatives of b-beta-aminoethyl-ergoline-i their salts and methods for the production thereof
CH617452A5 (da) *	1974-10-25	1980-05-30	Hoffmann La Roche
CH615929A5 (en) *	1975-06-02	1980-02-29	Sandoz Ag	Process for the preparation of novel ergoline compounds
CH622518A5 (en) *	1976-12-14	1981-04-15	Sandoz Ag	Process for the preparation of novel ergoline compounds
AU526764B2 (en) *	1978-09-08	1983-01-27	Farmitalia Carlo Erba S.P.A.	Ergoline derivatives
GB2056437A (en) *	1979-08-07	1981-03-18	Erba Farmitalia	Secoergoline derivatives
US4382940A (en) *	1979-12-06	1983-05-10	Farmitalia Carlo Erba S.P.A.	Ercoline derivatives and therapeutic compositions having CNS affecting activity

1983
- 1983-04-21 GB GB08310843A patent/GB2120242A/en not_active Withdrawn
- 1983-04-25 CS CS832921A patent/CS236874B2/cs unknown
- 1983-04-25 US US06/488,168 patent/US4657914A/en not_active Expired - Fee Related
- 1983-04-25 FI FI831406A patent/FI73996C/fi not_active IP Right Cessation
- 1983-04-25 DE DE19833314878 patent/DE3314878A1/de active Granted
- 1983-04-25 GR GR71190A patent/GR78842B/el unknown
- 1983-04-25 IE IE932/83A patent/IE53950B1/en not_active IP Right Cessation
- 1983-04-26 JP JP58072295A patent/JPS58194884A/ja active Granted
- 1983-04-26 IL IL68496A patent/IL68496A/xx not_active IP Right Cessation
- 1983-04-26 CH CH2256/83A patent/CH654305A5/it not_active IP Right Cessation
- 1983-04-27 SE SE8302379A patent/SE460967B/sv not_active IP Right Cessation
- 1983-04-27 CA CA000426874A patent/CA1210389A/en not_active Expired
- 1983-04-27 IT IT8320807A patent/IT1215630B/it active
- 1983-04-27 HU HU851631A patent/HU193527B/hu not_active IP Right Cessation
- 1983-04-27 FR FR8306926A patent/FR2526022B1/fr not_active Expired
- 1983-04-28 DK DK189983A patent/DK164058C/da not_active IP Right Cessation
- 1983-04-28 ZA ZA833008A patent/ZA833008B/xx unknown
- 1983-04-28 AU AU14029/83A patent/AU553851B2/en not_active Ceased
- 1983-04-29 AT AT0156783A patent/AT385035B/de not_active IP Right Cessation
- 1983-04-29 NL NL8301529A patent/NL191709C/xx not_active IP Right Cessation
- 1983-04-29 BE BE0/210660A patent/BE896609A/fr not_active IP Right Cessation

Also Published As

Publication number	Publication date
SE460967B (sv)	1989-12-11
US4657914A (en)	1987-04-14
IT1215630B (it)	1990-02-22
GB8310843D0 (en)	1983-05-25
IL68496A (en)	1985-06-30
IE53950B1 (en)	1989-04-26
FR2526022B1 (fr)	1985-06-14
DK164058C (da)	1992-10-12
DK164058B (da)	1992-05-04
GB2120242A (en)	1983-11-30
IT8320807A0 (it)	1983-04-27
DE3314878C2 (da)	1993-09-23
SE8302379D0 (sv)	1983-04-27
FI73996C (fi)	1987-12-10
CH654305A5 (it)	1986-02-14
FI831406L (fi)	1983-10-31
IL68496A0 (en)	1983-07-31
DK189983A (da)	1983-10-31
GR78842B (da)	1984-10-02
ATA156783A (de)	1987-07-15
FI831406A0 (fi)	1983-04-25
SE8302379L (sv)	1983-10-31
DE3314878A1 (de)	1983-11-03
IE830932L (en)	1983-10-30
NL191709B (nl)	1995-12-01
NL8301529A (nl)	1983-11-16
BE896609A (fr)	1983-08-16
NL191709C (nl)	1996-04-02
FR2526022A1 (fr)	1983-11-04
JPS58194884A (ja)	1983-11-12
CA1210389A (en)	1986-08-26
AU1402983A (en)	1983-11-03
CS236874B2 (en)	1985-05-15
ZA833008B (en)	1984-01-25
AU553851B2 (en)	1986-07-31
HU193527B (en)	1987-10-28
AT385035B (de)	1988-02-10
JPH0354668B2 (da)	1991-08-20
FI73996B (fi)	1987-08-31

Legal Events

Date	Code	Title	Description
1999-03-15	PBP	Patent lapsed

Publication	Publication Date	Title
DK301383A (da)	1984-01-02	Fremgangsmaade til fremstilling af imidazolderivater
DK95483A (da)	1983-08-28	Fremgangsmaade til fremstilling af tetrahydropyranderivater
DK163243C (da)	1992-06-29	Fremgangsmaade til fremstilling af cephalosporinderivater
DK324182A (da)	1983-01-22	Fremgangsmaade til fremstilling af ergolinderivater
DK241883A (da)	1983-12-04	Fremgangsmaade til fremstilling af 1-sulfo-2-oxoazetidinderivater
DK372283A (da)	1984-02-18	Fremgangsmaade til fremstilling af desoxyuridinderivater
DK494882A (da)	1983-05-07	Fremgangsmaade til fremstilling af ergolinderivater
DK155984D0 (da)	1984-03-14	Fremgangsmade til fremstilling af thiadiazolderivater
DK63683D0 (da)	1983-02-14	Fremgangsmade til fremstilling af cephemderivater
DK323083D0 (da)	1983-07-13	Fremgangsmade til fremstilling af 19-thio-androstanderivater
DK312584D0 (da)	1984-06-26	Fremgangsmaade til fremstilling af quinonderivater
DK435483D0 (da)	1983-09-23	Fremgangsmade til fremstilling af fenylcyklobutylderivater
DK427083D0 (da)	1983-09-19	Fremgangsmade til fremstilling af cephemderivater
DK140584A (da)	1984-09-09	Fremgangsmaade til fremstilling af carbapenemderivater
DK261883A (da)	1983-12-11	Fremgangsmaade til fremstilling af prostaglandin-d-derivater
DK164058C (da)	1992-10-12	Analogifremgangsmaade til fremstilling af ergolinderivater
DK162230C (da)	1992-03-02	Fremgangsmaade til fremstilling af 2-thiacephemderivater
DK426683A (da)	1984-03-31	Fremgangsmaade til fremstilling af oxacephalosporinderivater
DK317283A (da)	1984-01-09	Fremgangsmaade til fremstilling af thiadiazolderivater
DK340483D0 (da)	1983-07-25	Fremgangsmade til fremstilling af fluoralkylerede carbapenemderivater
DK482983A (da)	1984-04-22	Fremgangsmaade til fremstilling af phenylderivater
DK165583A (da)	1983-10-17	Fremgangsmaade til fremstilling af furanderivater
DK150781A (da)	1981-10-04	Fremgangsmaade til fremstilling af ergolinderivater
DK77082A (da)	1982-08-25	Fremgangsmaade til fremstilling af ergolinderivater
DK542383D0 (da)	1983-11-25	Fremgangsmade til fremstilling af acridanonderivater