DK1903105T3 - Fremgangsmåde til fermentativ fremstilling af proteiner - Google Patents

Fremgangsmåde til fermentativ fremstilling af proteiner

Info

Publication number
DK1903105T3
DK1903105T3 DK06121090.2T DK06121090T DK1903105T3 DK 1903105 T3 DK1903105 T3 DK 1903105T3 DK 06121090 T DK06121090 T DK 06121090T DK 1903105 T3 DK1903105 T3 DK 1903105T3
Authority
DK
Denmark
Prior art keywords
protein production
medium
fermentative
colistrain
escherichia
Prior art date
Application number
DK06121090.2T
Other languages
English (en)
Inventor
Tobias Dassler
Guenter Wich
Gerhard Schmid
Original Assignee
Wacker Chemie Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37467448&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1903105(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wacker Chemie Ag filed Critical Wacker Chemie Ag
Application granted granted Critical
Publication of DK1903105T3 publication Critical patent/DK1903105T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK06121090.2T 2006-09-22 2006-09-22 Fremgangsmåde til fermentativ fremstilling af proteiner DK1903105T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP06121090A EP1903105B1 (de) 2006-09-22 2006-09-22 Verfahren zur fermentativen Herstellung von Proteinen

Publications (1)

Publication Number Publication Date
DK1903105T3 true DK1903105T3 (da) 2010-06-28

Family

ID=37467448

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06121090.2T DK1903105T3 (da) 2006-09-22 2006-09-22 Fremgangsmåde til fermentativ fremstilling af proteiner

Country Status (6)

Country Link
US (1) US20080254511A1 (da)
EP (1) EP1903105B1 (da)
JP (1) JP4751374B2 (da)
AT (1) ATE465241T1 (da)
DE (1) DE502006006800D1 (da)
DK (1) DK1903105T3 (da)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006004871A1 (de) 2006-02-02 2007-08-09 Wacker Chemie Ag Mikroorganismenstamm zur Produktion von rekombinanten Proteinen
DK1903115T3 (da) * 2006-09-22 2011-05-23 Wacker Chemie Ag Fremgangsmåde til fermentativ fremstilling af antistoffer
DK1905839T4 (da) * 2006-09-22 2019-10-07 Wacker Chemie Ag Fremgangsmåde til fermentativ fremstilling af proteiner
DE102008063900A1 (de) 2008-12-19 2010-06-24 Wacker Chemie Ag Verfahren zur fermentativen Herstellung von heterologen Proteinen mittels Escherichia coli
JP6161541B2 (ja) * 2011-02-03 2017-07-12 ゾーマ テクノロジー リミテッド 細菌中の機能的タンパク質発現を向上させるための方法および物質
JP6362543B2 (ja) 2012-02-23 2018-07-25 ジュノ セラピューティクス ゲーエムベーハー 細胞および他の複雑な生物学的材料のクロマトグラフィーによる単離
CN102827904B (zh) * 2012-08-13 2014-06-04 安徽大学 一种大肠杆菌胞外生产外源蛋白的集成化方法
US9616114B1 (en) 2014-09-18 2017-04-11 David Gordon Bermudes Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity
US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
HK1258932A1 (zh) 2015-10-22 2019-11-22 Juno Therapeutics Gmbh 用於转导的方法、反应剂盒、反应剂和设备
CN108474791B (zh) 2015-10-22 2022-07-08 朱诺治疗学有限公司 培养细胞的方法及用于该方法的试剂盒和设备
DK3387111T3 (da) 2015-12-11 2021-05-10 Wacker Chemie Ag Mikroorganismestamme og fremgangsmåde til antibiotikafri, fermentativ fremstilling af lavmolekylære substanser og proteiner
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
MA49288A (fr) 2017-04-27 2020-03-04 Juno Therapeutics Gmbh Reactifs particulaires oligomères et leurs méthodes d'utilisation
EP3818073B1 (de) 2018-07-06 2025-12-03 Wacker Chemie AG Bakterienstamm zur freisetzung eines rekombinanten proteins in einem fermentationsverfahren
KR102546461B1 (ko) * 2018-07-24 2023-06-21 와커 헤미 아게 신규한 박테리아 lpp 돌연변이체 및 재조합 단백질의 분비 생산을 위한 그의 용도
EP3874024A1 (en) 2018-10-31 2021-09-08 Juno Therapeutics GmbH Methods for selection and stimulation of cells and apparatus for same
US11471497B1 (en) 2019-03-13 2022-10-18 David Gordon Bermudes Copper chelation therapeutics
DK4010500T3 (da) 2019-08-05 2025-05-05 Wacker Chemie Ag Bakteriestamme til frigivelse af et rekombinant protein i en fermenteringsfremgangsmåde
US10973908B1 (en) 2020-05-14 2021-04-13 David Gordon Bermudes Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine
US12537071B1 (en) 2020-07-22 2026-01-27 David Gordon Bermudes Bacteria having boolean control pathways expressing therapeutic proteins including immunotherapeutic cytotoxins
CN115029404B (zh) * 2021-03-04 2024-05-14 珠海联邦制药股份有限公司 用于lpp单基因敲除或突变的大肠杆菌分泌表达短肽类蛋白的发酵培养基及应用
WO2024261777A1 (en) * 2023-06-19 2024-12-26 Biological E Limited Expression cassettes for protein expression, method(s) and application(s) thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3891508A (en) * 1973-06-01 1975-06-24 Joseph M Merrick Method of rapid identification of gram-negative bacteria
US4643969A (en) * 1983-07-25 1987-02-17 The Research Foundation Of State University Of New York Novel cloning vehicles for polypeptide expression in microbial hosts
DE3538433A1 (de) * 1985-10-29 1987-05-14 Consortium Elektrochem Ind Dna-fragment mit dem cyclodextrin-glycosyl-transferase-strukturgen, expressionsvektor, mikroorganismen zur expression und herstellungsverfahren
US5618920A (en) * 1985-11-01 1997-04-08 Xoma Corporation Modular assembly of antibody genes, antibodies prepared thereby and use
US5223482A (en) * 1986-11-17 1993-06-29 Scios Nova Inc. Recombinant Alzheimer's protease inhibitory amyloid protein and method of use
DE3813107A1 (de) * 1988-04-19 1989-11-02 Consortium Elektrochem Ind Sekretormutante von escherichia coli
DE4009268A1 (de) * 1990-03-22 1991-09-26 Consortium Elektrochem Ind Sekretion von hirudinderivaten
US5521084A (en) * 1992-11-10 1996-05-28 Biostar, Inc. Bovine heat shock promoter and uses thereof
AU2002245142B2 (en) * 2000-12-14 2007-07-05 Genentech, Inc. Prokaryotically produced antibodies and uses thereof
DK1905839T4 (da) * 2006-09-22 2019-10-07 Wacker Chemie Ag Fremgangsmåde til fermentativ fremstilling af proteiner
DK1903115T3 (da) * 2006-09-22 2011-05-23 Wacker Chemie Ag Fremgangsmåde til fermentativ fremstilling af antistoffer

Also Published As

Publication number Publication date
JP2008073046A (ja) 2008-04-03
ATE465241T1 (de) 2010-05-15
EP1903105A1 (de) 2008-03-26
JP4751374B2 (ja) 2011-08-17
DE502006006800D1 (de) 2010-06-02
EP1903105B1 (de) 2010-04-21
US20080254511A1 (en) 2008-10-16

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