DK1903105T3 - Fremgangsmåde til fermentativ fremstilling af proteiner - Google Patents

Fremgangsmåde til fermentativ fremstilling af proteiner

Info

Publication number
DK1903105T3
DK1903105T3 DK06121090.2T DK06121090T DK1903105T3 DK 1903105 T3 DK1903105 T3 DK 1903105T3 DK 06121090 T DK06121090 T DK 06121090T DK 1903105 T3 DK1903105 T3 DK 1903105T3
Authority
DK
Denmark
Prior art keywords
protein production
medium
fermentative
colistrain
escherichia
Prior art date
Application number
DK06121090.2T
Other languages
English (en)
Inventor
Tobias Dassler
Guenter Wich
Gerhard Schmid
Original Assignee
Wacker Chemie Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37467448&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1903105(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wacker Chemie Ag filed Critical Wacker Chemie Ag
Application granted granted Critical
Publication of DK1903105T3 publication Critical patent/DK1903105T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK06121090.2T 2006-09-22 2006-09-22 Fremgangsmåde til fermentativ fremstilling af proteiner DK1903105T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP06121090A EP1903105B1 (de) 2006-09-22 2006-09-22 Verfahren zur fermentativen Herstellung von Proteinen

Publications (1)

Publication Number Publication Date
DK1903105T3 true DK1903105T3 (da) 2010-06-28

Family

ID=37467448

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06121090.2T DK1903105T3 (da) 2006-09-22 2006-09-22 Fremgangsmåde til fermentativ fremstilling af proteiner

Country Status (6)

Country Link
US (1) US20080254511A1 (da)
EP (1) EP1903105B1 (da)
JP (1) JP4751374B2 (da)
AT (1) ATE465241T1 (da)
DE (1) DE502006006800D1 (da)
DK (1) DK1903105T3 (da)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006004871A1 (de) 2006-02-02 2007-08-09 Wacker Chemie Ag Mikroorganismenstamm zur Produktion von rekombinanten Proteinen
EP1905839B2 (de) * 2006-09-22 2019-07-10 Wacker Chemie AG Verfahren zur fermentativen Herstellung von Proteinen
DK1903115T3 (da) * 2006-09-22 2011-05-23 Wacker Chemie Ag Fremgangsmåde til fermentativ fremstilling af antistoffer
DE102008063900A1 (de) 2008-12-19 2010-06-24 Wacker Chemie Ag Verfahren zur fermentativen Herstellung von heterologen Proteinen mittels Escherichia coli
WO2012106615A1 (en) * 2011-02-03 2012-08-09 Xoma Technology Ltd. Methods and materials for enhancing functional protein expression in bacteria
SG11201404991YA (en) 2012-02-23 2014-09-26 Stage Cell Therapeutics Gmbh Chromatographic isolation of cells and other complex biological materials
CN102827904B (zh) * 2012-08-13 2014-06-04 安徽大学 一种大肠杆菌胞外生产外源蛋白的集成化方法
US9616114B1 (en) 2014-09-18 2017-04-11 David Gordon Bermudes Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity
US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
MA45489A (fr) 2015-10-22 2018-08-29 Juno Therapeutics Gmbh Procédés de culture de cellules, kits et appareil associés
RU2761555C2 (ru) 2015-10-22 2021-12-09 Джуно Терапьютикс Гмбх Способы, наборы, средства и устройства для трансдукции
JP6828038B2 (ja) 2015-12-11 2021-02-10 ワッカー ケミー アクチエンゲゼルシャフトＷａｃｋｅｒ Ｃｈｅｍｉｅ ＡＧ 低分子量物質およびタンパク質の抗生物質を含まない発酵製造のための微生物株および方法
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
AU2018260380B2 (en) 2017-04-27 2025-02-13 Juno Therapeutics Gmbh Oligomeric particle reagents and methods of use thereof
US12139736B2 (en) 2018-07-06 2024-11-12 Wacker Chemie Ag Bacterial strain for releasing a recombinant protein in a fermentation method
WO2020020438A1 (de) 2018-07-24 2020-01-30 Wacker Chemie Ag Neue bakterielle lpp-mutante und deren verwendung zur sekretorischen herstellung von rekombinanten proteinen
WO2020089343A1 (en) 2018-10-31 2020-05-07 Juno Therapeutics Gmbh Methods for selection and stimulation of cells and apparatus for same
US11471497B1 (en) 2019-03-13 2022-10-18 David Gordon Bermudes Copper chelation therapeutics
ES3026707T3 (en) 2019-08-05 2025-06-12 Wacker Chemie Ag Bacterial strain for releasing a recombinant protein in a fermentation method
US10973908B1 (en) 2020-05-14 2021-04-13 David Gordon Bermudes Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine
US12537071B1 (en) 2020-07-22 2026-01-27 David Gordon Bermudes Bacteria having boolean control pathways expressing therapeutic proteins including immunotherapeutic cytotoxins
CN115029404B (zh) * 2021-03-04 2024-05-14 珠海联邦制药股份有限公司 用于lpp单基因敲除或突变的大肠杆菌分泌表达短肽类蛋白的发酵培养基及应用
WO2024261777A1 (en) * 2023-06-19 2024-12-26 Biological E Limited Expression cassettes for protein expression, method(s) and application(s) thereof
WO2026130658A1 (de) 2024-12-16 2026-06-25 Wacker Chemie Ag Sekretorische herstellung von rekombinanten proteinen unter verwendung von bakteriellen fnr-mutanten der familie der enterobacteriaceae

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3891508A (en) * 1973-06-01 1975-06-24 Joseph M Merrick Method of rapid identification of gram-negative bacteria
US4643969A (en) * 1983-07-25 1987-02-17 The Research Foundation Of State University Of New York Novel cloning vehicles for polypeptide expression in microbial hosts
DE3538433A1 (de) * 1985-10-29 1987-05-14 Consortium Elektrochem Ind Dna-fragment mit dem cyclodextrin-glycosyl-transferase-strukturgen, expressionsvektor, mikroorganismen zur expression und herstellungsverfahren
US5618920A (en) * 1985-11-01 1997-04-08 Xoma Corporation Modular assembly of antibody genes, antibodies prepared thereby and use
US5223482A (en) * 1986-11-17 1993-06-29 Scios Nova Inc. Recombinant Alzheimer's protease inhibitory amyloid protein and method of use
DE3813107A1 (de) * 1988-04-19 1989-11-02 Consortium Elektrochem Ind Sekretormutante von escherichia coli
DE4009268A1 (de) * 1990-03-22 1991-09-26 Consortium Elektrochem Ind Sekretion von hirudinderivaten
US5521084A (en) * 1992-11-10 1996-05-28 Biostar, Inc. Bovine heat shock promoter and uses thereof
EP1356052B1 (en) * 2000-12-14 2008-08-20 Genentech, Inc. Production of full antibodies in procaryotic cells
EP1905839B2 (de) * 2006-09-22 2019-07-10 Wacker Chemie AG Verfahren zur fermentativen Herstellung von Proteinen
DK1903115T3 (da) * 2006-09-22 2011-05-23 Wacker Chemie Ag Fremgangsmåde til fermentativ fremstilling af antistoffer

Also Published As

Publication number Publication date
JP2008073046A (ja) 2008-04-03
EP1903105A1 (de) 2008-03-26
ATE465241T1 (de) 2010-05-15
JP4751374B2 (ja) 2011-08-17
US20080254511A1 (en) 2008-10-16
EP1903105B1 (de) 2010-04-21
DE502006006800D1 (de) 2010-06-02

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