DK1907561T3 - Cellelinjer til ekspression af enzym, der er anvendeligt i fremstillingen af amiderede produkter - Google Patents

Cellelinjer til ekspression af enzym, der er anvendeligt i fremstillingen af amiderede produkter

Info

Publication number
DK1907561T3
DK1907561T3 DK06785535.3T DK06785535T DK1907561T3 DK 1907561 T3 DK1907561 T3 DK 1907561T3 DK 06785535 T DK06785535 T DK 06785535T DK 1907561 T3 DK1907561 T3 DK 1907561T3
Authority
DK
Denmark
Prior art keywords
amided
enzym
expression
manufacture
products
Prior art date
Application number
DK06785535.3T
Other languages
English (en)
Inventor
Duncan A Miller
Nozer M Mehta
Angelo P Consalvo
Original Assignee
Enteris Biopharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Enteris Biopharma Inc filed Critical Enteris Biopharma Inc
Application granted granted Critical
Publication of DK1907561T3 publication Critical patent/DK1907561T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK06785535.3T 2005-06-24 2006-06-23 Cellelinjer til ekspression af enzym, der er anvendeligt i fremstillingen af amiderede produkter DK1907561T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69361205P 2005-06-24 2005-06-24
PCT/US2006/024687 WO2007002532A2 (en) 2005-06-24 2006-06-23 Cell lines for expressing enzyme useful in the preparation of amidated products

Publications (1)

Publication Number Publication Date
DK1907561T3 true DK1907561T3 (da) 2013-12-02

Family

ID=37595928

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06785535.3T DK1907561T3 (da) 2005-06-24 2006-06-23 Cellelinjer til ekspression af enzym, der er anvendeligt i fremstillingen af amiderede produkter

Country Status (9)

Country Link
US (1) US8815583B2 (da)
EP (1) EP1907561B1 (da)
JP (3) JP4856177B2 (da)
CN (1) CN101287840B (da)
AU (1) AU2006261909B2 (da)
CA (1) CA2613471C (da)
DK (1) DK1907561T3 (da)
ES (1) ES2437068T3 (da)
WO (1) WO2007002532A2 (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8377863B2 (en) 2007-05-29 2013-02-19 Unigene Laboratories Inc. Peptide pharmaceutical for oral delivery
ES2622877T3 (es) 2009-01-22 2017-07-07 Keybioscience Ag Tratamiento para la obesidad
WO2011067283A1 (en) 2009-12-01 2011-06-09 Novo Nordisk A/S Novel peptidyl alpha-hydroxyglycine alpha-amidating lyases
US9102753B2 (en) 2011-06-15 2015-08-11 Ugp Therapeutics, Inc. Anti-inflammatory pharmaceutical products
US9006172B2 (en) 2011-11-02 2015-04-14 Keybioscience Ag Peptide analogs for treating diseases and disorders
EP3357540A1 (en) 2011-11-02 2018-08-08 KeyBioscience AG Combination of calcitonin mimetic and insulin sensitizer
US9457086B2 (en) 2013-03-05 2016-10-04 Enteris Biopharma, Inc. Pharmaceuticals for oral delivery
CN105722854B (zh) 2013-11-14 2020-08-04 关键生物科学有限公司 用于治疗疾病和病症的降钙素模拟物
WO2015195453A2 (en) * 2014-06-16 2015-12-23 Emd Millipore Corporation Methods for increasing the capacity of flow-through processes
ES2742704T3 (es) 2014-06-25 2020-02-17 Emd Millipore Corp Elementos, módulos y sistemas de filtro compactos, enrollados en espiral
CN108325391B (zh) 2014-08-29 2021-05-18 Emd 密理博公司 过滤液体进料的方法
GB201500263D0 (en) 2015-01-08 2015-02-25 Keybioscience Ag Calcitonin analogues for treating diseases and disorders
DK3244878T3 (da) 2015-01-12 2022-10-17 Enteris Biopharma Inc Faste orale sammensætningsformer
CA3023486C (en) 2016-06-09 2022-03-29 Emd Millipore Corporation Radial-path filter elements, systems and methods of using same
GB201704429D0 (en) 2017-03-21 2017-05-03 Keybioscience Ag Calcitonin mimetics for treating diseases and disorders
GB201707955D0 (en) 2017-05-18 2017-07-05 Keybioscience Ag Dual amylin and calcitonin receptor agonists for treating diseases and disorders
WO2019078095A1 (en) 2017-10-16 2019-04-25 Ajinomoto Co., Inc. PROCESS FOR PRODUCTION OF PROTEIN HAVING ALPHA-HYDROXYLANTIC PEPTIDYLGLYCIN MONOOXYGENASE ACTIVITY
GB201813677D0 (en) 2018-08-22 2018-10-03 Keybioscience Ag Calcitonin mimetics for treating diseases and disorders
GB201813678D0 (en) 2018-08-22 2018-10-03 Keybioscience Ag Acylated calcitonin mimetics
GB202001024D0 (en) 2020-01-24 2020-03-11 Key Bioscience Ag Oxyntomodulin mimetics
WO2025133225A1 (en) * 2023-12-22 2025-06-26 Pam Theragnostics Gmbh Pharmaceutical combination of peptide-gly and peptidylglycine alpha-amidating monooxygenase (pam)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4708934A (en) * 1984-09-27 1987-11-24 Unigene Laboratories, Inc. α-amidation enzyme
AU580145B2 (en) * 1985-02-13 1989-01-05 Scios Nova Inc. Human metallothionein-ii promoter in mammalian expression system
US5789234A (en) * 1987-08-14 1998-08-04 Unigene Laboratories, Inc. Expression systems for amidating enzyme
US6087129A (en) * 1996-01-19 2000-07-11 Betagene, Inc. Recombinant expression of proteins from secretory cell lines
WO1998046722A1 (en) 1997-04-16 1998-10-22 Unigene Laboratories Inc. Direct expression of peptides into culture media
WO2000049162A2 (en) 1999-02-19 2000-08-24 Athersys, Inc. Compositions and methods for non-targeted activation of endogenous genes
SI1583830T1 (sl) 2003-01-07 2006-12-31 Symphogen As Postopek za pripravo rekombinantnih poliklonskih proteinov
US8227241B2 (en) 2004-03-12 2012-07-24 Unigene Laboratories, Inc. Bacterial host cell for the direct expression of peptides
US7445911B2 (en) * 2004-11-24 2008-11-04 Unigene Laboratories Inc. Enzymatic reactions in the presence of keto acids

Also Published As

Publication number Publication date
US8815583B2 (en) 2014-08-26
EP1907561A2 (en) 2008-04-09
CN101287840A (zh) 2008-10-15
JP5677918B2 (ja) 2015-02-25
JP5568703B2 (ja) 2014-08-13
JP2012016354A (ja) 2012-01-26
AU2006261909A1 (en) 2007-01-04
JP4856177B2 (ja) 2012-01-18
CA2613471C (en) 2016-09-06
CN101287840B (zh) 2013-04-10
JP2011139714A (ja) 2011-07-21
WO2007002532A3 (en) 2007-09-13
ES2437068T3 (es) 2014-01-08
AU2006261909B2 (en) 2011-08-11
JP2008543344A (ja) 2008-12-04
US20060292672A1 (en) 2006-12-28
CA2613471A1 (en) 2007-01-04
WO2007002532A2 (en) 2007-01-04
EP1907561B1 (en) 2013-08-28
EP1907561A4 (en) 2009-07-15

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