DK1930002T3 - Brug af hydroxybenzosyreester forbindelser i fremstillingen af et medikament til forebyggelse og behandling af HPV infektion - Google Patents

Brug af hydroxybenzosyreester forbindelser i fremstillingen af et medikament til forebyggelse og behandling af HPV infektion Download PDF

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Publication number
DK1930002T3
DK1930002T3 DK06761527.8T DK06761527T DK1930002T3 DK 1930002 T3 DK1930002 T3 DK 1930002T3 DK 06761527 T DK06761527 T DK 06761527T DK 1930002 T3 DK1930002 T3 DK 1930002T3
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acid ester
hydroxybenzoic acid
manufacture
hpv
medicament according
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DK06761527.8T
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English (en)
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Weihua F 22 Northtower Qin
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Shenghua Guangzhou Pharmaceutical Science &
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/222Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007Effervescent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Emergency Medicine (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Biotechnology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Biophysics (AREA)
  • Gynecology & Obstetrics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dispersion Chemistry (AREA)
  • Cardiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Detergent Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Claims (9)

1. Brug af en hydroxybenzosyreester som angivet ved formlen (1) nedenfor i fremstillingen af et medikament til forebyggelse og behandling af human eller dyrisk HPV infektion, condyloma acuminata induceret af HPY, cervical erosion in HPV positive patienter, kronisk cervicitis in HPV positive patienter, eller støttende i behandlingen af cervical cancer, hvori R er en Ci-π alkylgruppe, RI, R2, R3, R4 og R5 uafhængigt er OH eller H; hvoraf mindst to er OH.
(0
2. Brug af en hydroxybenzosyreester i fremstillingen af et medikament i henhold til krav 1, hvori nævnte R er en C i-8 alkylgruppe.
3. Brug af en hydroxybenzosyreester i fremstillingen af et medikament i henhold til kravene 1 eller 2, hvori nævnte R er en C1-3 alkylgruppe.
4. Brug af en hydroxybenzosyreester i fremstillingen af et medikament i henhold til et hvilken som helst af kravene 1 til 3, hvori mindst tre af nævnte RI, R2, R3, R4 og R5 er OH.
5. Brug af en hydroxybenzosyreester i fremstillingen af et medikament i henhold til et hvilken som helst af kravene 1 til 3, hvori nævnte hydroxybenzosyreester er udvalgt fra gruppen bestående af 2,4-dihydroxybenzosyreester, 3,4-dihydroxybenzosyreester, 2,3,4-trihydroxybenzosyreester, 3,4,5-trihydroxybenzosyreester og 3,4,6-trihydroxybenzosyreester.
6. Brug af en hydroxybenzosyreester i fremstillingen af et medikament i henhold til et hvilken som helst af kravene 1 til 5, hvori nævnte hydroxybenzosyreester er udvalgt fra gruppen bestående af 2,3,4-trihydroxybenzosyreester, 3,4,5-trihydroxybenzosyreester og 3,4,6-trihydroxybenzosyreester.
7. Brug af en hydroxybenzosyreester i fremstillingen af et medikament i henhold til et hvilken som helst af kravene 1 til 6, hvori nævnte hydroxybenzosyreester er 3,4,5-trihydroxybenzosyreester.
8. Brug af en hydroxybenzosyreester i fremstillingen af et medikament i henhold til et hvilken som helst af kravene 1 til 7, hvori nævnte forbindelse og/eller en sammensætning omfattende en sådan forbindelse som en aktiv ingrediens fremstilles som pulver, opløsning, tablet, kapsel, granulat eller væske med diverse adjuvanter for injektion eller oral formulering eller fremstillet som salve, gel, lotion, suppositorie, diaphragma eller spray med diverse adjuvanter for en hudmucosaformulering, eller anden farmaceutisk acceptable formulering.
9. Brug af en hydroxybenzosyreester i fremstillingen af et medikament i henhold til et hvilken som helst af kravene 1 til 7, hvori nævnte forbindelse og/eller en sammensætning omfattende en sådan forbindelse som en aktiv ingrediens bruges i personlige hygiejneprodukter, hvori sådanne personlige hygiejneprodukter omfatter håndsæber, hånddesinfektionsmidler, body cleansers, body cleansing gels, body washing soaps, hygiejneservietter, ansigtsservietter, næsesprays eller kombinationer deraf.
DK06761527.8T 2005-08-02 2006-07-21 Brug af hydroxybenzosyreester forbindelser i fremstillingen af et medikament til forebyggelse og behandling af HPV infektion DK1930002T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CNB2005100122870A CN100427082C (zh) 2005-08-02 2005-08-02 羟基苯甲酸酯及其类似物在制备预防和治疗病毒性感染药物中的应用
PCT/CN2006/001792 WO2007014515A1 (en) 2005-08-02 2006-07-21 Use of hydroxybenzoic acid ester and analogues for the manufacture of a mendicament for the prevention and treatment of virus infection

Publications (1)

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DK1930002T3 true DK1930002T3 (da) 2016-04-11

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DK06761527.8T DK1930002T3 (da) 2005-08-02 2006-07-21 Brug af hydroxybenzosyreester forbindelser i fremstillingen af et medikament til forebyggelse og behandling af HPV infektion

Country Status (21)

Country Link
EP (1) EP1930002B1 (da)
JP (1) JP5473328B2 (da)
KR (1) KR100922605B1 (da)
CN (1) CN100427082C (da)
AP (1) AP2658A (da)
AU (1) AU2006275232B2 (da)
BR (1) BRPI0616536B8 (da)
CA (1) CA2617659C (da)
CY (1) CY1117480T1 (da)
DK (1) DK1930002T3 (da)
EA (1) EA016576B1 (da)
ES (1) ES2567130T3 (da)
HU (1) HUE027244T2 (da)
IL (1) IL189162A (da)
MX (1) MX2008001673A (da)
NZ (1) NZ566153A (da)
PL (1) PL1930002T3 (da)
SI (1) SI1930002T1 (da)
UA (1) UA90159C2 (da)
WO (1) WO2007014515A1 (da)
ZA (1) ZA200801635B (da)

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CN102603522B (zh) * 2011-01-23 2015-04-22 复旦大学 苯酚类衍生物及其在制备抗乙肝病毒药物中的用途
KR101401154B1 (ko) * 2011-02-22 2014-05-30 경희대학교 산학협력단 메틸 갈레이트를 포함하는 조절 t 세포 활성 억제용 약학적 조성물
PL404138A1 (pl) * 2013-05-31 2014-12-08 Warszawski Uniwersytet Medyczny Pochodne kwasu benzoesowego jako inhibitory receptora IL-15Rα
CN103599093B (zh) * 2013-11-18 2016-06-01 中国医学科学院生物医学工程研究所 一种抗hpv药物制剂及用途
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WO2017101873A1 (zh) 2015-12-18 2017-06-22 深圳瑞健生命科学研究院有限公司 一种预防或治疗放射性和化学性损伤的方法
WO2017101872A1 (zh) 2015-12-18 2017-06-22 深圳瑞健生命科学研究院有限公司 一种用于预防和治疗宫颈糜烂的方法
CN105748506B (zh) * 2016-03-03 2018-08-17 青岛海洋生物医药研究院股份有限公司 褐藻酸硫酸酯在制备预防和治疗由人乳头瘤状病毒引起的疾病的药物和保健品中的应用
WO2019087888A1 (ja) * 2017-10-31 2019-05-09 富士フイルム株式会社 組成物、抗菌組成物、抗ウイルス用組成物、抗ノロウイルス用組成物、スプレー、ワイパー
WO2019087881A1 (ja) * 2017-10-31 2019-05-09 富士フイルム株式会社 抗ウイルス用組成物、抗ノロウイルス用組成物、スプレー、ワイパー
WO2019087884A1 (ja) * 2017-10-31 2019-05-09 富士フイルム株式会社 組成物、抗菌組成物、抗ウイルス用組成物、抗ノロウイルス用組成物、スプレー、ワイパー
CN111419833B (zh) * 2020-06-02 2023-04-07 上海爱启医药技术有限公司 没食子酸的药物应用
CN114146082B (zh) * 2020-09-07 2025-09-05 盈科瑞(横琴)药物研究院有限公司 对羟基苯甲酸甲酯及其钠盐抗冠状病毒的用途
CN114146078B (zh) * 2020-09-07 2025-09-16 盈科瑞(横琴)药物研究院有限公司 对羟基苯甲酸乙酯抗冠状病毒感染的应用
CN112375803B (zh) * 2020-11-16 2024-05-07 石河子大学 五倍子中抗炎活性成分没食子酸乙酯的筛选方法及其用途
CN118489806A (zh) * 2024-05-13 2024-08-16 浙江大学 多酚在制备预防和/或缓解动物锌过载所致肠道免疫应激或肠道损伤制剂中的应用

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Also Published As

Publication number Publication date
EP1930002A4 (en) 2010-04-21
CN100427082C (zh) 2008-10-22
EP1930002B1 (en) 2016-01-06
KR20080036128A (ko) 2008-04-24
IL189162A0 (en) 2008-08-07
BRPI0616536A2 (pt) 2012-12-25
AU2006275232B2 (en) 2010-12-02
WO2007014515A1 (en) 2007-02-08
CA2617659C (en) 2013-02-26
EA016576B1 (ru) 2012-06-29
ES2567130T3 (es) 2016-04-20
CY1117480T1 (el) 2017-04-26
NZ566153A (en) 2011-07-29
JP5473328B2 (ja) 2014-04-16
KR100922605B1 (ko) 2009-10-21
BRPI0616536B1 (pt) 2020-05-26
JP2009502985A (ja) 2009-01-29
UA90159C2 (ru) 2010-04-12
HUE027244T2 (en) 2016-09-28
SI1930002T1 (sl) 2016-06-30
AU2006275232A1 (en) 2007-02-08
EP1930002A1 (en) 2008-06-11
HK1113747A1 (en) 2008-10-17
AP2658A (en) 2013-05-09
MX2008001673A (es) 2008-11-06
IL189162A (en) 2014-04-30
EA200800467A1 (ru) 2008-10-30
PL1930002T3 (pl) 2016-07-29
ZA200801635B (en) 2009-06-24
CA2617659A1 (en) 2007-02-08
BRPI0616536B8 (pt) 2021-05-25
CN1907276A (zh) 2007-02-07

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