DK1978925T3 - Termohærdende neutraliseret chitosansammensætning, der danner en hydrogel, lyofilisat og fremgangsmåder til fremstilling deraf - Google Patents

Termohærdende neutraliseret chitosansammensætning, der danner en hydrogel, lyofilisat og fremgangsmåder til fremstilling deraf

Info

Publication number
DK1978925T3
DK1978925T3 DK05824526T DK05824526T DK1978925T3 DK 1978925 T3 DK1978925 T3 DK 1978925T3 DK 05824526 T DK05824526 T DK 05824526T DK 05824526 T DK05824526 T DK 05824526T DK 1978925 T3 DK1978925 T3 DK 1978925T3
Authority
DK
Denmark
Prior art keywords
hydrogel
lyophilizate
processes
making
composition forming
Prior art date
Application number
DK05824526T
Other languages
English (en)
Inventor
Yannic Schuetz
Virginie Caratti-Besson
Olivier Jordan
Robert Gurny
Original Assignee
Medidom Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medidom Lab filed Critical Medidom Lab
Application granted granted Critical
Publication of DK1978925T3 publication Critical patent/DK1978925T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/20—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/042—Polysaccharides
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
    • C08B37/0027—2-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
    • C08B37/003—Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials Engineering (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Inorganic Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK05824526T 2005-12-23 2005-12-23 Termohærdende neutraliseret chitosansammensætning, der danner en hydrogel, lyofilisat og fremgangsmåder til fremstilling deraf DK1978925T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2005/013980 WO2007073749A1 (en) 2005-12-23 2005-12-23 Thermosetting neutralized chitosan composition forming a hydrogel, lyophilizate, and processes for producing the same

Publications (1)

Publication Number Publication Date
DK1978925T3 true DK1978925T3 (da) 2009-12-14

Family

ID=36686051

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05824526T DK1978925T3 (da) 2005-12-23 2005-12-23 Termohærdende neutraliseret chitosansammensætning, der danner en hydrogel, lyofilisat og fremgangsmåder til fremstilling deraf

Country Status (16)

Country Link
US (1) US8945609B2 (da)
EP (1) EP1978925B1 (da)
JP (1) JP5474353B2 (da)
CN (1) CN101360479B (da)
AT (1) ATE439122T1 (da)
BR (1) BRPI0520742A2 (da)
CA (1) CA2634479C (da)
CY (1) CY1109620T1 (da)
DE (1) DE602005016030D1 (da)
DK (1) DK1978925T3 (da)
ES (1) ES2331620T3 (da)
MX (1) MX2008007820A (da)
PL (1) PL1978925T3 (da)
PT (1) PT1978925E (da)
SI (1) SI1978925T1 (da)
WO (1) WO2007073749A1 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5725862B2 (ja) * 2007-10-30 2015-05-27 ヴィスコゲル アーベーＶｉｓｃｏｇｅｌ Ａｂ キトサン組成物
BRPI0921625A2 (pt) 2008-11-04 2016-01-05 Univ Kentucky Res Foundation Inc composicoes baseadas em d-tagatose e metodos para previnir e tratar aterosclerose, sindrome metabolica, e sintomas dos mesmos
JP5804453B2 (ja) * 2009-05-14 2015-11-04 国立大学法人 東京大学 結晶性ポリオール微粒子及びその調製方法
US9547011B2 (en) 2013-03-14 2017-01-17 Tricol Biomedical, Inc. Biocompatible and bioabsorbable derivatized chitosan compositions
FR3016882A1 (fr) 2014-01-30 2015-07-31 Sofradim Production Procede de preparation de chitosane a haut degre d’acetylation
ES2904359T3 (es) * 2014-02-20 2022-04-04 Ortho Regenerative Tech Inc Composiciones poliméricas liofilizadas para mezclar con plasma rico en plaquetas para formar implantes para la reparación de tejidos y/o composiciones para inyecciones terapéuticas intraarticulares
AU2015221390B2 (en) 2014-02-20 2019-03-07 Ortho Regenerative Technologies Inc. Lyophilized polymer scaffold compositions, processes for preparation and use in anabolic wound repair
WO2016066195A1 (en) * 2014-10-29 2016-05-06 Laboratoire Medidom Sa Heat-sterilized formulation comprising chitosan and process of preparation thereof
CN113336870B (zh) * 2021-05-21 2023-04-25 珠海市自然之旅生物技术有限公司 一种托酚酮-壳聚糖衍生物及其制备方法和应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5550187A (en) * 1988-11-21 1996-08-27 Collagen Corporation Method of preparing crosslinked biomaterial compositions for use in tissue augmentation
US5541304A (en) * 1994-05-02 1996-07-30 Hercules Incorporated Crosslinked hydrogel compositions with improved mechanical performance
TW389694B (en) * 1995-08-17 2000-05-11 Novartis Ag Compositions including o-carboxyalkyl chitosan and methods of use in ophthalmics
US5955096A (en) * 1996-06-25 1999-09-21 Brown University Research Foundation Methods and compositions for enhancing the bioadhesive properties of polymers using organic excipients
CA2212300A1 (en) * 1997-08-04 1999-02-04 Abdellatif Chenite In vitro or in vivo gelfying chitosan and therapeutic uses thereof
DE69939959D1 (de) * 1998-09-02 2009-01-02 Kaneka Corp Polymer, Verfahren zu seiner Herstellung und Zusammensetzung
AU1375301A (en) 1999-11-15 2001-05-30 Bio Syntech Canada Inc Temperature-controlled and ph-dependant self-gelling biopolymeric aqueous solution
US20040047892A1 (en) * 2000-11-15 2004-03-11 Desrosiers Eric Andre Filler composition for soft tissue augmentation and reconstructive surgery
FR2822842B1 (fr) * 2001-03-30 2004-11-19 Genevrier Lab Procede de preparation d'un neo-tissu cartilagineux
JP4321007B2 (ja) * 2002-04-25 2009-08-26 凸版印刷株式会社 多糖類複合体及びその製造方法
EP1730216A1 (en) * 2004-03-22 2006-12-13 Universite De Geneve Pseudo-thermosetting neutralized chitosan composition forming a hydrogel and a process for producing the same

Also Published As

Publication number Publication date
CN101360479B (zh) 2012-03-21
CY1109620T1 (el) 2014-08-13
JP2009520705A (ja) 2009-05-28
US20090004230A1 (en) 2009-01-01
PT1978925E (pt) 2009-11-19
SI1978925T1 (sl) 2010-01-29
CA2634479A1 (en) 2007-07-05
PL1978925T3 (pl) 2010-01-29
HK1125867A1 (en) 2009-08-21
DE602005016030D1 (de) 2009-09-24
ATE439122T1 (de) 2009-08-15
MX2008007820A (es) 2008-09-11
BRPI0520742A2 (pt) 2010-01-12
US8945609B2 (en) 2015-02-03
CN101360479A (zh) 2009-02-04
CA2634479C (en) 2013-02-05
WO2007073749A1 (en) 2007-07-05
EP1978925A1 (en) 2008-10-15
EP1978925B1 (en) 2009-08-12
JP5474353B2 (ja) 2014-04-16
ES2331620T3 (es) 2010-01-11

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