DK1991697T3 - DNA-konformation (LOOP-strukturer) ved normal og anormal genekspression - Google Patents

DNA-konformation (LOOP-strukturer) ved normal og anormal genekspression

Info

Publication number
DK1991697T3
DK1991697T3 DK07712741.3T DK07712741T DK1991697T3 DK 1991697 T3 DK1991697 T3 DK 1991697T3 DK 07712741 T DK07712741 T DK 07712741T DK 1991697 T3 DK1991697 T3 DK 1991697T3
Authority
DK
Denmark
Prior art keywords
gene expression
normal
abnormal gene
loop structures
dna conformation
Prior art date
Application number
DK07712741.3T
Other languages
English (en)
Inventor
Leonid Leonidovich Nikitenko
Alexandre Akoulitchev
Aroul Selvam Ramadass
Original Assignee
Isis Innovation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Isis Innovation filed Critical Isis Innovation
Application granted granted Critical
Publication of DK1991697T3 publication Critical patent/DK1991697T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Saccharide Compounds (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK07712741.3T 2006-02-17 2007-02-19 DNA-konformation (LOOP-strukturer) ved normal og anormal genekspression DK1991697T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0603251.0A GB0603251D0 (en) 2006-02-17 2006-02-17 DNA conformation
PCT/GB2007/000564 WO2007093819A2 (en) 2006-02-17 2007-02-19 Dna conformation (loop structures) in normal and abnormal gene expression

Publications (1)

Publication Number Publication Date
DK1991697T3 true DK1991697T3 (da) 2011-09-19

Family

ID=36142050

Family Applications (1)

Application Number Title Priority Date Filing Date
DK07712741.3T DK1991697T3 (da) 2006-02-17 2007-02-19 DNA-konformation (LOOP-strukturer) ved normal og anormal genekspression

Country Status (15)

Country Link
US (2) US9777327B2 (da)
EP (1) EP1991697B1 (da)
JP (1) JP5345857B2 (da)
CN (1) CN101384734B (da)
AT (1) ATE519864T1 (da)
AU (1) AU2007216315B2 (da)
CA (1) CA2642331C (da)
DK (1) DK1991697T3 (da)
ES (1) ES2368767T3 (da)
GB (1) GB0603251D0 (da)
MY (1) MY182608A (da)
NO (1) NO343718B1 (da)
NZ (1) NZ571201A (da)
WO (1) WO2007093819A2 (da)
ZA (1) ZA200807948B (da)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114841294A (zh) * 2022-07-04 2022-08-02 杭州德适生物科技有限公司 一种检测染色体结构异常的分类器模型训练方法及装置

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0603251D0 (en) 2006-02-17 2006-03-29 Isis Innovation DNA conformation
EP2245459A1 (en) 2008-01-23 2010-11-03 Herlev Hospital Ykl-40 as a general marker for non-specific disease
GB0810051D0 (en) * 2008-06-02 2008-07-09 Oxford Biodynamics Ltd Method of diagnosis
AU2009291312A1 (en) 2008-09-15 2010-03-18 Herlev Hospital YKL-40 as a marker for gastrointestinal cancers
AU2011274642B2 (en) * 2010-07-09 2015-05-21 Cergentis B.V. 3-d genomic region of interest sequencing strategies
US10323279B2 (en) 2012-08-14 2019-06-18 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10584381B2 (en) 2012-08-14 2020-03-10 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10273541B2 (en) 2012-08-14 2019-04-30 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10221442B2 (en) 2012-08-14 2019-03-05 10X Genomics, Inc. Compositions and methods for sample processing
US11591637B2 (en) 2012-08-14 2023-02-28 10X Genomics, Inc. Compositions and methods for sample processing
US10752949B2 (en) 2012-08-14 2020-08-25 10X Genomics, Inc. Methods and systems for processing polynucleotides
CN114891871A (zh) 2012-08-14 2022-08-12 10X基因组学有限公司 微胶囊组合物及方法
US9701998B2 (en) 2012-12-14 2017-07-11 10X Genomics, Inc. Methods and systems for processing polynucleotides
US9951386B2 (en) 2014-06-26 2018-04-24 10X Genomics, Inc. Methods and systems for processing polynucleotides
EP3567116A1 (en) 2012-12-14 2019-11-13 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10533221B2 (en) 2012-12-14 2020-01-14 10X Genomics, Inc. Methods and systems for processing polynucleotides
US9411930B2 (en) * 2013-02-01 2016-08-09 The Regents Of The University Of California Methods for genome assembly and haplotype phasing
KR20230003659A (ko) 2013-02-08 2023-01-06 10엑스 제노믹스, 인크. 폴리뉴클레오티드 바코드 생성
US10059989B2 (en) 2013-05-23 2018-08-28 The Board Of Trustees Of The Leland Stanford Junior University Transposition of native chromatin for personal epigenomics
US9694361B2 (en) 2014-04-10 2017-07-04 10X Genomics, Inc. Fluidic devices, systems, and methods for encapsulating and partitioning reagents, and applications of same
KR20170026383A (ko) 2014-06-26 2017-03-08 10엑스 제노믹스, 인크. 핵산 서열의 분석
EP4574974A3 (en) 2014-06-26 2025-10-08 10x Genomics, Inc. Methods of analyzing nucleic acids from individual cells or cell populations
US12312640B2 (en) 2014-06-26 2025-05-27 10X Genomics, Inc. Analysis of nucleic acid sequences
AU2015296029B2 (en) 2014-08-01 2022-01-27 Dovetail Genomics, Llc Tagging nucleic acids for sequence assembly
JP2017532042A (ja) 2014-10-29 2017-11-02 10エックス ゲノミクス,インコーポレイテッド 標的化核酸配列決定のための方法及び組成物
US9975122B2 (en) 2014-11-05 2018-05-22 10X Genomics, Inc. Instrument systems for integrated sample processing
AU2016207023B2 (en) 2015-01-12 2019-12-05 10X Genomics, Inc. Processes and systems for preparing nucleic acid sequencing libraries and libraries prepared using same
JP6777966B2 (ja) 2015-02-17 2020-10-28 ダブテイル ゲノミクス エルエルシー 核酸配列アセンブリ
EP4286516A3 (en) 2015-02-24 2024-03-06 10X Genomics, Inc. Partition processing methods and systems
AU2016222719B2 (en) 2015-02-24 2022-03-31 10X Genomics, Inc. Methods for targeted nucleic acid sequence coverage
WO2016154540A1 (en) 2015-03-26 2016-09-29 Dovetail Genomics Llc Physical linkage preservation in dna storage
JP2018527016A (ja) * 2015-06-24 2018-09-20 オックスフォード バイオダイナミックス リミテッド 染色体相互作用の検出
SG11201803289VA (en) 2015-10-19 2018-05-30 Dovetail Genomics Llc Methods for genome assembly, haplotype phasing, and target independent nucleic acid detection
KR102723865B1 (ko) 2015-12-04 2024-10-29 10엑스 제노믹스, 인크. 핵산 분석을 위한 방법 및 조성물
US10975417B2 (en) 2016-02-23 2021-04-13 Dovetail Genomics, Llc Generation of phased read-sets for genome assembly and haplotype phasing
GB201608000D0 (en) 2016-05-06 2016-06-22 Oxford Biodynamics Ltd Chromosome detection
WO2017197343A2 (en) 2016-05-12 2017-11-16 10X Genomics, Inc. Microfluidic on-chip filters
WO2017197300A1 (en) 2016-05-13 2017-11-16 Dovetail Genomics Llc Recovering long-range linkage information from preserved samples
WO2017197338A1 (en) 2016-05-13 2017-11-16 10X Genomics, Inc. Microfluidic systems and methods of use
ES2971286T3 (es) * 2016-12-01 2024-06-04 Oxford BioDynamics PLC Aplicación de interacciones cromosómicas epigenéticas en diagnóstico de cáncer
US10011872B1 (en) 2016-12-22 2018-07-03 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10815525B2 (en) 2016-12-22 2020-10-27 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10550429B2 (en) 2016-12-22 2020-02-04 10X Genomics, Inc. Methods and systems for processing polynucleotides
CA3047888C (en) * 2016-12-23 2025-05-27 Oxford BioDynamics PLC Method for typing epigenetic chromosome interactions
US12264411B2 (en) 2017-01-30 2025-04-01 10X Genomics, Inc. Methods and systems for analysis
EP4310183B1 (en) 2017-01-30 2025-07-09 10X Genomics, Inc. Methods and systems for droplet-based single cell barcoding
CN116064732A (zh) 2017-05-26 2023-05-05 10X基因组学有限公司 转座酶可接近性染色质的单细胞分析
US10844372B2 (en) 2017-05-26 2020-11-24 10X Genomics, Inc. Single cell analysis of transposase accessible chromatin
CN111511930B (zh) 2017-11-03 2024-11-22 牛津生物动力有限责任公司 通过染色体相互作用遗传调节免疫响应
EP3625361A1 (en) 2017-11-15 2020-03-25 10X Genomics, Inc. Functionalized gel beads
WO2019099908A1 (en) 2017-11-17 2019-05-23 10X Genomics, Inc. Methods and systems for associating physical and genetic properties of biological particles
WO2019152543A1 (en) 2018-01-31 2019-08-08 Dovetail Genomics, Llc Sample prep for dna linkage recovery
WO2019152108A1 (en) 2018-02-05 2019-08-08 The Board Of Trustees Of The Leland Stanford Junior University Systems and methods for multiplexed measurements in single and ensemble cells
EP3775271B1 (en) 2018-04-06 2025-03-12 10X Genomics, Inc. Systems and methods for quality control in single cell processing
JP2022523564A (ja) 2019-03-04 2022-04-25 アイオーカレンツ, インコーポレイテッド 機械学習を使用するデータ圧縮および通信
AU2020381516A1 (en) * 2019-11-15 2022-06-02 Phase Genomics Inc. Chromosome conformation capture from tissue samples
CN114550817B (zh) * 2022-01-25 2022-12-23 云南大学 基于多特征的ctcf介导染色质环预测方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002220521A1 (en) 2000-11-29 2002-06-11 Statens Seruminstitut A screening assay for detecting chromosome rearrangements or recombinations
CN1231596C (zh) * 2001-12-27 2005-12-14 赵兴波 利用线粒体dna指纹进行动物遗传信息鉴定的方法
CN1515692A (zh) * 2003-01-02 2004-07-28 缪金明 “锚定点灯”式寡核苷酸芯片的检测技术
EP1713938A2 (en) 2004-02-09 2006-10-25 Thomas Jefferson University DIAGNOSIS AND TREATMENT OF CANCERS WITH MicroRNA LOCATED IN OR NEAR CANCER-ASSOCIATED CHROMOSOMAL FEATURES
US20060015264A1 (en) 2004-06-02 2006-01-19 Mcshea Andrew Interfering stem-loop sequences and method for identifying
AU2006264564B2 (en) 2005-07-04 2012-04-19 Erasmus University Medical Center Chromosome conformation capture-on-chip (4c) assay
GB0603251D0 (en) 2006-02-17 2006-03-29 Isis Innovation DNA conformation

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114841294A (zh) * 2022-07-04 2022-08-02 杭州德适生物科技有限公司 一种检测染色体结构异常的分类器模型训练方法及装置

Also Published As

Publication number Publication date
WO2007093819A2 (en) 2007-08-23
JP5345857B2 (ja) 2013-11-20
US11384396B2 (en) 2022-07-12
EP1991697A2 (en) 2008-11-19
NO20083957L (no) 2008-11-14
ATE519864T1 (de) 2011-08-15
US20180080081A1 (en) 2018-03-22
MY182608A (en) 2021-01-26
CN101384734B (zh) 2013-10-30
US9777327B2 (en) 2017-10-03
CN101384734A (zh) 2009-03-11
HK1125416A1 (en) 2009-08-07
CA2642331A1 (en) 2007-08-23
JP2009526543A (ja) 2009-07-23
US20090186352A1 (en) 2009-07-23
ZA200807948B (en) 2009-11-25
WO2007093819A3 (en) 2007-10-04
GB0603251D0 (en) 2006-03-29
EP1991697B1 (en) 2011-08-10
NZ571201A (en) 2011-07-29
ES2368767T3 (es) 2011-11-22
AU2007216315A1 (en) 2007-08-23
AU2007216315B2 (en) 2012-10-04
CA2642331C (en) 2018-06-19
NO343718B1 (no) 2019-05-20

Similar Documents

Publication Publication Date Title
ZA200807948B (en) DNA Conformation (loop structures) in normal and abnormal gene expression
AR088827A1 (es) Metodos para tratar, diagnosticar, y monitorear la enfermedad de alzheimer
ATE493290T1 (de) Alcotestgerät
MX361882B (es) Deteccion en tiempo real de virus de influenza.
WO2008122670A3 (en) Human diabetes susceptibility tnfrsf10b gene
WO2009085234A3 (en) Use of micro-rna as a biomarker of immunomodulatory drug activity
EP4303584A3 (en) Methods for detecting signatures of disease or conditions in bodily fluids
WO2009048673A3 (en) Stochastic confinement to detect, manipulate, and utilize molecules and organisms
MX2010009766A (es) Ensayo de proteasa.
GB2467704A (en) Methods of monitoring conditions by sequence analysis
WO2008027098A3 (en) Biosensor for measurement of species in a body fluid
BRPI0714563B8 (pt) métodos para detectar a pré-disposição à ou estágio de um câncer em um indivíduo mamífero, para triagem, identificação ou otimização de um medicamento anti-câncer, para modificação de um gene de mamífero in vitro e para avaliação da eficácia de um medicamento anti-câncer ou medicamento candidato
EP2518158A4 (en) MARKERS FOR PANCREATIC CARCINOMA, PROOF PROCESSES, KITS AND BIOCHIPS THEREOF
WO2009149319A3 (en) Gene expression profiles associated with asthma exacerbation attacks
WO2013090386A3 (en) Methods and kits for room temperature in situ detection of a target nucleic acid in a biological sample
EP2075341A4 (en) METHOD FOR THE INVESTIGATION, DETERMINATION OR EVALUATION BY MEANS OF GENE EXPRESSION ANALYSIS
WO2010090834A3 (en) Netrin-1 as a biomarker of injury and disease
EP1988178A3 (en) Nucleotide primer set and nucleotide probe for detecting genotype of serum amyloid A1(SAA1)
BRPI1008936B8 (pt) método in vitro para detectar pré-disposição para ou diagnóstico e/ou prognóstico de fibrose hepática ou cirrose ocorrendo em um indivíduo humano
MX381530B (es) Método in vitro para el diagnóstico de la enfermedad de niemann-pick.
WO2010144553A3 (en) Methods for diagnosing blood vessel reocclusion
WO2008115517A3 (en) Methods for identifying stem cells by detecting autofluorescence of cells and syncytia
DE602007007697D1 (de) Verfahren zur Ermittlung von Arzneimittelempfindlichkeit durch Analyse von GIRK-Kanal-Genen
WO2008145701A9 (en) Method for predicting the outcome of a critically ill patient
WO2012135146A3 (en) Role of ifng methylation in inflammatory bowel disease