DK200401111A - Fremgangsmåde til fremstilling af et humant pluripotent granulocyt kolonistimulerende faktorprodukt - Google Patents
Fremgangsmåde til fremstilling af et humant pluripotent granulocyt kolonistimulerende faktorprodukt Download PDFInfo
- Publication number
- DK200401111A DK200401111A DK200401111A DKPA200401111A DK200401111A DK 200401111 A DK200401111 A DK 200401111A DK 200401111 A DK200401111 A DK 200401111A DK PA200401111 A DKPA200401111 A DK PA200401111A DK 200401111 A DK200401111 A DK 200401111A
- Authority
- DK
- Denmark
- Prior art keywords
- stimulating factor
- colony stimulating
- granulocyte colony
- obtd
- peptide
- Prior art date
Links
- 102000004269 Granulocyte Colony-Stimulating Factor Human genes 0.000 title abstract description 3
- 108010017080 Granulocyte Colony-Stimulating Factor Proteins 0.000 title abstract description 3
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract description 3
- 238000000034 method Methods 0.000 title description 6
- 108020004511 Recombinant DNA Proteins 0.000 title 1
- 230000000694 effects Effects 0.000 title 1
- 230000003394 haemopoietic effect Effects 0.000 title 1
- 210000004027 cell Anatomy 0.000 abstract description 6
- 230000004071 biological effect Effects 0.000 abstract description 2
- 229920001184 polypeptide Polymers 0.000 abstract description 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract description 2
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 2
- 108091029865 Exogenous DNA Proteins 0.000 abstract 1
- 230000000295 complement effect Effects 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 230000002068 genetic effect Effects 0.000 abstract 1
- 241000288906 Primates Species 0.000 description 2
- 125000003275 alpha amino acid group Chemical group 0.000 description 1
- 230000001377 granulocytopoietic effect Effects 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 210000004962 mammalian cell Anatomy 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
Landscapes
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Description
PATENTKRAV 1. Fremgangsmåde til fremstilling af et humant pluripotent granulocyt kolonistimulerende faktor{hpG-CSF)produkt med in vivo granulocytopoietiske, biologiske egenskaber som naturligt forekommende hpG-CSF, kendetegnet ved, at fremgangsmåden omfatter følgende trin: (a) under hensigtsmæssige næringsbetingelser at dyrke pattedyrsceller omfattende andet promotor DNA end hpG-CSF promotor DNA og operativt forbundet med DNA kodende for et hpg-CSF polypeptid med den modne aminosyresekvens ifølge figur Vil; og (b) isolere det af cellerne eksprimerede hpg-CSF produkt . 2. Fremgangsmåde ifølge krav 1, kende tegnet ved, at promotor DNA er viral promotor DNA. 3. Fremgangsmåde ifølge krav 1, kende tegnet ved, at cellerne er primat-celler. 4. Fremgangsmåde ifølge krav 3, kende tegnet ved, at primat-cellerne er COS celler.
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US76895985A | 1985-08-23 | 1985-08-23 | |
| US76895985 | 1985-08-23 | ||
| US83554886 | 1986-03-03 | ||
| US06/835,548 US4810643A (en) | 1985-08-23 | 1986-03-03 | Production of pluripotent granulocyte colony-stimulating factor |
| DK200301685 | 2003-11-12 | ||
| DK200301685A DK175551B1 (da) | 1985-08-23 | 2003-11-12 | Isoleret polypeptid med hæmatopoietiske biologiske egenskaber som naturligt forekommende hpG-CSF, DNA-sekvens kodende for denne, plasmider indeholdende sekvensen, hermed transformerede/transficerede..... |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK200401111A true DK200401111A (da) | 2004-07-15 |
| DK176002B1 DK176002B1 (da) | 2005-11-21 |
Family
ID=32872384
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK200401111A DK176002B1 (da) | 1985-08-23 | 2004-07-15 | Fremgangsmåde til fremstilling af et humant pluripotent granulocyt kolonistimulerende faktorprodukt |
Country Status (1)
| Country | Link |
|---|---|
| DK (1) | DK176002B1 (da) |
-
2004
- 2004-07-15 DK DK200401111A patent/DK176002B1/da not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DK176002B1 (da) | 2005-11-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUP | Patent expired |