DK2032712T3 - Regulering af syremetabolitproduktion - Google Patents

Regulering af syremetabolitproduktion

Info

Publication number: DK2032712T3
Authority: DK; Denmark
Prior art keywords: regulation; acid metabolite; metabolite production; acid; mycophenolic acid
Prior art date: 2006-06-29

Application number

DK07796600.0T

Other languages

English (en)

Inventor

Zdenek Pokluda

Josef Satke

Josef Valik

Vladimir Vala

Original Assignee

Ivax Pharmaceuticals Sro

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-06-29

Filing date

2007-06-29

Publication date

2010-05-25

2007-06-29 Application filed by Ivax Pharmaceuticals Sro filed Critical Ivax Pharmaceuticals Sro

2010-05-25 Application granted granted Critical

2010-05-25 Publication of DK2032712T3 publication Critical patent/DK2032712T3/da

Links

239000002253 acid Substances 0.000 title abstract 2
239000002207 metabolite Substances 0.000 title abstract 2
HPNSFSBZBAHARI-UHFFFAOYSA-N micophenolic acid Natural products OC1=C(CC=C(C)CCC(O)=O)C(OC)=C(C)C2=C1C(=O)OC2 HPNSFSBZBAHARI-UHFFFAOYSA-N 0.000 abstract 2
HPNSFSBZBAHARI-RUDMXATFSA-N mycophenolic acid Chemical compound OC1=C(C\C=C(/C)CCC(O)=O)C(OC)=C(C)C2=C1C(=O)OC2 HPNSFSBZBAHARI-RUDMXATFSA-N 0.000 abstract 2
229960000951 mycophenolic acid Drugs 0.000 abstract 2
241000228168 Penicillium sp. Species 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
- C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Bioinformatics & Cheminformatics (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
Microbiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Biomedical Technology (AREA)
Cell Biology (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DK07796600.0T 2006-06-29 2007-06-29 Regulering af syremetabolitproduktion DK2032712T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US81814506P	2006-06-29	2006-06-29
US84734406P	2006-09-25	2006-09-25
PCT/US2007/015234 WO2008002665A1 (en)	2006-06-29	2007-06-29	Regulation of acid metabolite production

Publications (1)

Publication Number	Publication Date
DK2032712T3 true DK2032712T3 (da)	2010-05-25

Family

ID=38626338

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK07796600.0T DK2032712T3 (da)	2006-06-29	2007-06-29	Regulering af syremetabolitproduktion

Country Status (12)

Country	Link
US (1)	US20080009050A1 (da)
EP (1)	EP2032712B1 (da)
JP (1)	JP2009505681A (da)
KR (1)	KR20080069571A (da)
AT (1)	ATE457358T1 (da)
BR (1)	BRPI0702901A2 (da)
DE (1)	DE602007004728D1 (da)
DK (1)	DK2032712T3 (da)
ES (1)	ES2339297T3 (da)
PL (1)	PL2032712T3 (da)
SI (1)	SI2032712T1 (da)
WO (1)	WO2008002665A1 (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP2024506A1 (en) *	2007-04-11	2009-02-18	Teva Gyógyszergyár Zártköruen Muködo Részvénytársaság	Method for reducing impurity level in mycophenolic acid fermentation
CN109929890B (zh) *	2019-05-08	2020-12-04	广东蓝宝制药有限公司	一种麦考酚酸的发酵工艺

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4115197A (en) *	1977-03-21	1978-09-19	Eli Lilly And Company	Procedure for obtaining penicillium species mutants with improved ability to synthesize mycophenolic acid
DE4407441C2 (de) *	1993-03-10	1996-02-29	Forschungszentrum Juelich Gmbh	Fermentationsverfahren zur kontinuierlichen Citronensäuregewinnung
US6225073B1 (en) *	1994-07-07	2001-05-01	Dade Behring Marburg Gmbh	Immunoassay for mycophenolic acid
ID18663A (id) *	1996-04-12	1998-04-30	Novartis Ag	Komposisi farmasi berlapis enterik
US6083728A (en) *	1997-10-17	2000-07-04	Regents Of The University Of Minnesota	Production of glutamate using wild type Bacillus methanolicus
GB9812413D0 (en) *	1998-06-10	1998-08-05	Glaxo Group Ltd	Compound and its use
US6107052A (en) *	1999-06-09	2000-08-22	Roche Diagnostics Corporation	Enzymatic measurement of mycophenolic acid
WO2001064931A1 (en) *	2000-02-29	2001-09-07	Biocon India Limited	Manufacture and purification of mycophenolic acid
CZ292123B6 (cs) *	2001-06-08	2003-08-13	Ivax Pharmaceuticals S.R.O.	Způsob přípravy mykofenolátu mofetilu
BR0214971A (pt) *	2002-08-29	2004-12-14	Biocon Ltd	Processo para a produção de um imunossupressor
US6955892B2 (en) *	2002-11-12	2005-10-18	Akzo Nobel N.V.	Feeding processes for fermentation
DE602004015310D1 (de) *	2003-09-11	2008-09-04	Sandoz Ag	Verfahren zur herstellung von mycophenolatmofetil
US20070135638A1 (en) *	2004-02-20	2007-06-14	Ivax Pharmaceuticals S.R.O.	Process for the manufacture of lysergic acid
MXPA06005659A (es) *	2004-04-26	2007-04-10	Teva Gyogyszergyar Zartkoruen	Proceso para preparacion de acido micofenolico y derivados de ester del mismo.
EP1740563A2 (en) *	2004-04-27	2007-01-10	Teva Gyógyszergyár Zártköruen Muködo Részvenytarsaság	Mycophenolate mofetil impurity
US7439373B2 (en) *	2004-07-20	2008-10-21	TEVA Gyógyszergyár Zártkörúen Múködö Részvénytársaság	Crystalline mycophenolate sodium
EP1624070A1 (en) *	2004-08-05	2006-02-08	Tecnimede-Sociedade Tecnico-Medicinal, S.A.	Process for the production of mycophenolic acid
US7138504B2 (en) *	2004-08-12	2006-11-21	Microgenics Corporation	Reagents and methods for mycophenolic acid immunoassay

2007
- 2007-06-29 SI SI200730216T patent/SI2032712T1/sl unknown
- 2007-06-29 US US11/823,905 patent/US20080009050A1/en not_active Abandoned
- 2007-06-29 ES ES07796600T patent/ES2339297T3/es active Active
- 2007-06-29 PL PL07796600T patent/PL2032712T3/pl unknown
- 2007-06-29 EP EP07796600A patent/EP2032712B1/en not_active Not-in-force
- 2007-06-29 BR BRPI0702901-2A patent/BRPI0702901A2/pt not_active IP Right Cessation
- 2007-06-29 DK DK07796600.0T patent/DK2032712T3/da active
- 2007-06-29 KR KR1020087005089A patent/KR20080069571A/ko not_active Ceased
- 2007-06-29 AT AT07796600T patent/ATE457358T1/de not_active IP Right Cessation
- 2007-06-29 JP JP2008529382A patent/JP2009505681A/ja active Pending
- 2007-06-29 DE DE602007004728T patent/DE602007004728D1/de active Active
- 2007-06-29 WO PCT/US2007/015234 patent/WO2008002665A1/en not_active Ceased

Also Published As

Publication number	Publication date
JP2009505681A (ja)	2009-02-12
EP2032712A1 (en)	2009-03-11
BRPI0702901A2 (pt)	2011-03-15
KR20080069571A (ko)	2008-07-28
ATE457358T1 (de)	2010-02-15
PL2032712T3 (pl)	2010-07-30
DE602007004728D1 (de)	2010-03-25
WO2008002665A1 (en)	2008-01-03
ES2339297T3 (es)	2010-05-18
SI2032712T1 (sl)	2010-06-30
EP2032712B1 (en)	2010-02-10
US20080009050A1 (en)	2008-01-10

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