DK2069517T3 - Fremgangsmåde til fremstilling af optisk aktiv 2-benzyloxycyclohexylamin - Google Patents
Fremgangsmåde til fremstilling af optisk aktiv 2-benzyloxycyclohexylaminInfo
- Publication number
- DK2069517T3 DK2069517T3 DK07803441.0T DK07803441T DK2069517T3 DK 2069517 T3 DK2069517 T3 DK 2069517T3 DK 07803441 T DK07803441 T DK 07803441T DK 2069517 T3 DK2069517 T3 DK 2069517T3
- Authority
- DK
- Denmark
- Prior art keywords
- benzyloxycyclohexylamine
- optically active
- preparation
- relates
- trans
- Prior art date
Links
- NTHNRYLIXJZHRZ-UHFFFAOYSA-N 2-phenylmethoxycyclohexan-1-amine Chemical compound NC1CCCCC1OCC1=CC=CC=C1 NTHNRYLIXJZHRZ-UHFFFAOYSA-N 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 230000010933 acylation Effects 0.000 abstract 2
- 238000005917 acylation reaction Methods 0.000 abstract 2
- NTHNRYLIXJZHRZ-CHWSQXEVSA-N (1r,2r)-2-phenylmethoxycyclohexan-1-amine Chemical compound N[C@@H]1CCCC[C@H]1OCC1=CC=CC=C1 NTHNRYLIXJZHRZ-CHWSQXEVSA-N 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/001—Amines; Imines
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
- C12P41/007—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures by reactions involving acyl derivatives of racemic amines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06120597 | 2006-09-13 | ||
| PCT/EP2007/059594 WO2008031852A1 (de) | 2006-09-13 | 2007-09-12 | Verfahren zur herstellung von optisch aktivem 2-benzyloxycyclohexylamin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2069517T3 true DK2069517T3 (da) | 2011-05-23 |
Family
ID=38947716
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK07803441.0T DK2069517T3 (da) | 2006-09-13 | 2007-09-12 | Fremgangsmåde til fremstilling af optisk aktiv 2-benzyloxycyclohexylamin |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20090280544A1 (da) |
| EP (1) | EP2069517B1 (da) |
| JP (1) | JP5039787B2 (da) |
| CN (1) | CN101517088B (da) |
| AT (1) | ATE499448T1 (da) |
| DE (1) | DE502007006556D1 (da) |
| DK (1) | DK2069517T3 (da) |
| ES (1) | ES2361065T3 (da) |
| SI (1) | SI2069517T1 (da) |
| WO (1) | WO2008031852A1 (da) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009023978A (ja) * | 2007-07-23 | 2009-02-05 | Kaneka Corp | トランス−２−ベンジロキシシクロヘキシルアミンの製造法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4332738A1 (de) * | 1993-09-25 | 1995-03-30 | Basf Ag | Racematspaltung primärer und sekundärer Amine durch Enzym-katalysierte Acylierung |
| US5442117A (en) * | 1993-12-13 | 1995-08-15 | Albemarle Corporation | Enantiomeric resolution |
| US6214608B1 (en) * | 1995-02-03 | 2001-04-10 | Basf Aktiengesellschaft | Resolution of racemates of primary and secondary heteroatom-substitued amines by enzyme-catalyzed acylation |
| DE19534208A1 (de) * | 1995-09-15 | 1997-03-20 | Basf Ag | Spaltung von optisch aktiven Amiden |
| DE19837745A1 (de) * | 1998-08-20 | 2000-02-24 | Basf Ag | Enzymkatalysierte Racematspaltung von primären Aminen |
| DE19931847A1 (de) * | 1999-07-09 | 2001-01-11 | Basf Ag | Immobilisierte Lipase |
| DE50213015D1 (de) * | 2001-10-22 | 2008-12-24 | Basf Se | Lipase-varianten |
| US20050164955A1 (en) * | 2003-11-06 | 2005-07-28 | Gross Richard A. | Antifungal properties of various forms of sophorolipids |
-
2007
- 2007-09-12 US US12/440,811 patent/US20090280544A1/en not_active Abandoned
- 2007-09-12 CN CN200780034051.4A patent/CN101517088B/zh not_active Expired - Fee Related
- 2007-09-12 JP JP2009527820A patent/JP5039787B2/ja not_active Expired - Fee Related
- 2007-09-12 DE DE502007006556T patent/DE502007006556D1/de active Active
- 2007-09-12 AT AT07803441T patent/ATE499448T1/de active
- 2007-09-12 SI SI200730555T patent/SI2069517T1/sl unknown
- 2007-09-12 EP EP07803441A patent/EP2069517B1/de not_active Not-in-force
- 2007-09-12 ES ES07803441T patent/ES2361065T3/es active Active
- 2007-09-12 DK DK07803441.0T patent/DK2069517T3/da active
- 2007-09-12 WO PCT/EP2007/059594 patent/WO2008031852A1/de not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| JP2010503393A (ja) | 2010-02-04 |
| EP2069517A1 (de) | 2009-06-17 |
| ES2361065T3 (es) | 2011-06-13 |
| WO2008031852A1 (de) | 2008-03-20 |
| DE502007006556D1 (de) | 2011-04-07 |
| CN101517088A (zh) | 2009-08-26 |
| US20090280544A1 (en) | 2009-11-12 |
| EP2069517B1 (de) | 2011-02-23 |
| CN101517088B (zh) | 2013-05-01 |
| SI2069517T1 (sl) | 2011-05-31 |
| ATE499448T1 (de) | 2011-03-15 |
| JP5039787B2 (ja) | 2012-10-03 |
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